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Dependence of dynamic contour and Goldmann applanation tonometries on peripheral corneal thickness

International Journal of Ophthalmology(English edition) 2017年第10期10卷 1521-1527页

作者： Federico Saenz-Frances Claudia Sanz-Pozo Lara Borrego-Sanz luis ja?ez Laura MoralesFernandez Jose Maria Martinez-de-la-Casa Julian Garcia-Sanchez Julian Garcia-Feijoo Enrique Santos-Bueso Ophthalmology Department Clinico Universitario San Carlos HospitalComplutense University Institute of Knowledge Technology Complutense University

AIM：To determine the effects of peripheral corneal thickness（PCT）on dynamic contour tonometry（DCT）and Goldmann applanation tonometry（GAT）.METHODS：A cross-sectional *** created a software which calculates the corneal contour（CC）as a function of the radius from the corneal apex to each pixel of the *** software generates a central circumference with a radius of 1 mm and the remainder of the cornea is segmented in 5 rings concentric with corneal apex being its diameter not constant around the corneal circumference as a consequence of the irregular CC but keeping constant the diameter of each ring in each direction of the *** was determined as the mean thickness of the most eccentric *** weighted scatterplot smoothing（LOWESS）regression was used to determine the pattern of the relationship between PCT and both DCT and GAT ***,two multivariable linear regression models were *** each of them,the dependant variable was intraocular pressure（IOP）as determined using GAT and DCT *** both of the models the predictive variable was PCT though LOWESS regression pattern was used to model the relationship between the dependant variables and the predictor *** and sex were also introduced control variables along with their first-degree interactions with *** outcome measures include amount of IOP variation explained through regression models（R2）and regression coefficients（B）.RESULTS：Subjects included 109 eyes of 109 healthy *** regression suggested that a 2nd-degree polynomial would be suitable to model the relationshipbetween both DCT and GAT with *** PCT was introduced in both models as a linear and quadratic *** age nor sex nor interactions were statistically significant in both *** GAT model,R2was 17.14%（F=9.02;P=0.0002）,PCT linear term B was-1.163（95%CI：-1.163,-0.617）.PCT quadratic term B was 0.00081（95%CI：0.00043,0.00118）.For DCT model R2was 14.28%（F=9.29;P=0.0002

关键词： Goldmann applanation tonometry dynamic contour tonometry peripheral corneal thickness corneal thickness

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Reconstruction after pancreatoduodenectomy:Pancreatojejunostomy vs pancreatogastrostomy

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World Journal of Gastrointestinal Oncology 2014年第9期6卷 369-376页

作者： Tatiana Gómez Ana Palomares Mario Serradilla luis Tejedor Department of Surgery Hospital Punta de Europa Division of Hepato-Pancreatic-Biliary Surgery Department of SurgeryComplejo Hospitalario de Jaén

Pancreatic surgeons try to find the best technique for reconstruction after pancreatoduodenectomy(PD) in order to decrease postoperative complications,mainly pancreatic fistulas(PF).In this work,we compare the two most frequent techniques of reconstruction after PD,pancreatojejunostomy(PJ) and pancreatogastrostomy(PG),in order to determine which of the two is better.A systematic review of the literature was performed,including major meta-analysis articles,clinical randomized trials,systematic reviews,and retrospective studies.A total of 64 articles were finally *** and PG are usually responsible for most of the postoperative morbidity,mainly due to the onset of PF,being considered a major trigger of life-threatening complications such as intra-abdominal abscess and *** included systematic reviews reported a significant difference only in the incidence of intraabdominal collections favouring ***,delayed gastric emptying and mortality were not *** there was heterogeneity between these studies,all were conducted in specialized centers by highly experienced surgeons,and the surgical care was likely to be similar for all the *** disadvantages of PG include an increased incidence of delayed gastric emptying and of main pancreatic duct obstruction due to overgrowth by the gastric *** function appears to be worse after PG than after PJ,resulting in severe atrophic changes in the remnant *** on the type of PJ or PG used,the PF rate and other complications can also be *** best method to deal with the pancreatic stump after PD remains *** choice of method of pancreatic anastomosis could be based on individual experience and on the surgeon's preference and adherence to basic principles such as good exposure and *** conclusion,up to now none of the techniques can be considered superior or be recommended as standard for reconstruction after PD.

关键词： Pancreatoduodenectomy Pancreatojeju-nostomy Pancreatogastrostomy Pancreatic fistula Pancreatic cancer Surgical technique

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Large-Scale Group Decision Making:A Systematic Review and a Critical Analysis

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IEEE/CAA Journal of Automatica Sinica 2022年第6期9卷 949-966页

作者： Diego García-Zamora Alvaro Labella Weiping Ding Rosa M.Rodríguez luis Martínez Department of Computer Science University of JaénJaén 23071Spain IEEE School of Information Science and Technology Nantong UniversityNantong 226019China

The society in the digital transformation era demands new decision schemes such as e-democracy or based on social *** novel decision schemes require the participation of many experts/decision makers/stakeholders in the decision *** a result,large-scale group decision making(LSGDM)has attracted the attention of many researchers in the last decade and many studies have been conducted in order to face the challenges associated with the ***,this paper aims at reviewing the most relevant studies about LSGDM,identifying the most profitable research trends and analyzing them from a critical point of *** do so,the Web of Science database has been consulted by using different *** these results a total of 241 contributions were found and a selection process regarding language,type of contribution and actual relation with the studied topic was then carried *** 87 contributions finally selected for this review have been analyzed from four points of view that have been highly remarked in the topic,such as the preference structure in which decision-makers’opinions are modeled,the group decision rules used to define the decision making process,the techniques applied to verify the quality of these models and their applications to real world problems ***,a critical analysis of the main limitations of the existing proposals is ***,taking into account these limitations,new research lines for LSGDM are proposed and the main challenges are stressed out.

关键词： Challenges large-scale consensus models large-scale group decision making(LSGDM) systematic review

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Anatomical characterization of central, apical and minimal corneal thickness

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International Journal of Ophthalmology(English edition) 2014年第4期7卷 668-672页

作者： Federico Saenz-Frances Martha Cecilia Bermúdez-Vallecilla Lara Borrego-Sanz luis jaez J osé Marìa Martinez-de-la-Casa Laura Morales-Fernandez Enrique Santos-Bueso Julián Garcia-Sanchez Julián Garcia-Feijoo Department of Ophthalmology Hospital Clínico San CarlosUniversidad Complutense de Madrid Instituto de Tecnologìa del Conocimiento Universidad Complutense de Madrid

·AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness(pupil center) in relation to the corneal apex.·METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex(AT),minimum corneal thickness(MT) and corneal thickness at the pupil center(PT) were determined using the pentacam. Distances from the corneal apex to MT(MD)and PT(PD) were calculated and their quadrant position(taking the corneal apex as the reference) determined:point of minimum thickness(MC) and point of central thickness(PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume(determined using the Pentacam)and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.·RESULTS: MT was located at a mean distance of 0.909 mm from the apex(79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume(B =-0.024; 95% CI:-0.043 to-0.004). No significant relations were identified in the linear regression model for PD or the multinomial logisticregressions for MC and PC.·CONCLUSION: MT was typically located at the inferiortemporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.

关键词： cornealthickness anatomy glaucoma

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The Yukawa and Exponential Potentials for a Galaxy’s Spherical Central Bulge*

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Journal of Modern Physics 2023年第S1期14卷 1755-1761页

作者： José luis Garrido Pestaña Departamento de Física Universidad de Jaén Campus Las Lagunillas Jaén Espa&#241a

By adding an extra term to the Newtonian potential, matter outside the orbit of a star adds to the gravitational acceleration acting on that star. In this work, we solve the Poisson equation for non-Newtonian potentials of a spherically symmetric distribution of mass. We derive equations for calculating the centripetal acceleration and velocity of galactic disk stars that are due to the Newtonian and exponential potentials of the galaxy’s central bulge.

关键词： Galaxies: Kinematics and Dynamics Gravitation General Physics (Physics Education)

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COVID‑19 and tourism sector stock price in Spain:medium‑term relationship through dynamic regression models

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Financial Innovation 2023年第1期9卷 257-280页

作者： Isabel Carrillo‑Hidalgo Juan Ignacio Pulido‑Fernández Joséluis Durán‑Román jairo Casado‑Montilla Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑13423071 JaénSpain Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑27323071 JaénSpain Laboratory of Analysis and Innovation in Tourism University of JaénParaje Las Lagunillas S/ND3‑21723071 JaénSpain

The global pandemic,coronavirus disease 2019(COVID-19),has significantly affected tourism,especially in Spain,as it was among the first countries to be affected by the pandemic and is among the world’s biggest tourist *** market values are responding to the evolution of the pandemic,especially in the case of tourist ***,being able to quantify this relationship allows us to predict the effect of the pandemic on shares in the tourism sector,thereby improving the response to the crisis by policymakers and ***,a dynamic regression model was developed to predict the behavior of shares in the Spanish tourism sector according to the evolution of the COVID-19 pandemic in the medium *** has been confirmed that both the number of deaths and cases are good predictors of abnormal stock prices in the tourism sector.

关键词： COVID-19 Stock exchange Tourism stock Dynamic regression models Spain

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Dark Future for Dark Matter

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Journal of Modern Physics 2020年第10期11卷 1589-1597页

作者： Donald H. Eckhardt José luis Garrido Pestañ a Canterbury NH USA Departamento de Física Universidad de Jaén Campus Las Lagunillas Jaén Espa&ntilde a

The prevailing cosmological constant and cold dark matter (ΛCDM) cosmic concordance model accounts for the radial expansion of the universe after the Big Bang. The model appears to be authoritative because it is based on the Einstein gravitational field equation. However, a thorough scrutiny of the underlying theory calls into question the suitability of the field equation, which states that the Einstein tensor Gμv is a constant multiple of the stress-energy tensor Tμv when they both are evaluated at the same 4D space-time point: Gμv = 8πkTμv, where k is the gravitational constant. Notwithstanding its venerable provenance, this equation is incorrect unless the cosmic pressure is p = 0;but then all that remains of the Einstein equation is the Poisson equation which models the Newtonian gravity field. This shortcoming is not resolved by adding the cosmological constant term to the field equation, Gμv +Λ gμv =8πkTμv

关键词： Classical General Relativity General Relativity and Gravitation: Fundamental Problems and General Formalism Fundamental Aspects of Astrophysics Relativity and Gravitation Dark Energy Mathematical and Relativistic Aspects of Cosmology

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Modifications of L-Glutamine and L-Leucine Transport in Proliferating Lymphocytes

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Journal of Biosciences and Medicines 2015年第3期3卷 104-109页

作者： Francisco Sanchez Jose luis Gil Macarena Perán Department of Biochemistry Molecular Biology and Immunology University of Málaga Málaga Spain Department of Health Sciences University of Jaén Jaén Spain

Lymphocytes respond to mitogens that stimulate proliferation by increasing theirs metabolic activity. In this study we investigate L-Glutamine and L-Leucine uptake as markers of cell response to Concavalina A (ConcaA) stimulation, using a high-resolution flow technique. We found that lymphocytes induced to blast transformation enhanced rate and efficiency of amino acid uptake during cell proliferation. Considering that increases in transport is the first quantifiable response of cells during malignant transformation, amino acid uptake could also be useful as an early marker of malignancy.

关键词： Cell Membrane Transport Lymphocytes L-Glutamine L-Leucine Malignancy Biomarkers

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A MULTI-GRANULAR LINGUISTIC EVALUATION MODEL FOR ENGINEERING SYSTEMS

A MULTI-GRANULAR LINGUISTIC EVALUATION MODEL FOR ENGINEERING...

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第11届国际模糊系统协会世界大会

作者： luis Martínez L.G.Pérez Dpto.de Informática Universidad de jaén JaénSpain

＜正＞ Before of implementing a design for an Engineering System different design proposals should be evaluated to choose the most suitable one. This evaluation process is carried out according to different criteria, the main problem is that the knowledge about these criteria is usually vague and incomplete. In this contribution, we use the fuzzy linguistic approach and the Dempster-Shafer theory of evidence to deal with it. We shall propose an evaluation model of different designs based on the Safety, Cost and Technical performance criteria. To develop this evaluation model we shall define a multi-granular linguistic evaluation framework and after propose a evaluation model based on a decision process.

关键词： Engineering systems decision making multi-granular linguistic information

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Prioritizing real estate enterprises based on credit risk assessment:an integrated multi‑criteria group decision support framework

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Financial Innovation 2023年第1期9卷 2939-2991页

作者： Zhen‑Song Chen Jia Zhou Chen‑Ye Zhu Zhu‑Jun Wang Sheng‑Hua Xiong Rosa M.Rodríguez luis Martínez Mirosław J.Skibniewski School of Civil Engineering Wuhan UniversityWuhan 430072China College of Civil Aviation Safety Engineering Civil Aviation Flight University of ChinaGuanghan 618307China School of Management Xi’an Jiaotong UniversityXi’an 710049China Department of Computer Science University of Jaén23071 JaénSpain Department of Civil and Environmental Engineering University of MarylandCollege ParkMD 20742‑3021USA Institute for Theoretical and Applied Informatics Polish Academy of SciencesGliwicePoland Chaoyang University of Technology TaizhongTaiwan

Credit risk assessment involves conducting a fair review and evaluation of an assessed subject’s solvency and *** the context of real estate enterprises,credit risk assessment provides a basis for banks and other financial institutions to choose suitable investment ***,it encourages real estate enterprises to abide by market norms and provide reliable information for the standardized management of the real estate ***,Chinese real estate companies are hesitant to disclose their actual operating data due to privacy concerns,making subjective evalu-ation approaches inevitable,occupying important roles in accomplishing Chinese real estate enterprise credit risk assessment *** improve the normative and reliability of credit risk assessment for Chinese real estate enterprises,this study proposes an integrated multi-criteria group decision-making ***,a credit risk assessment index for Chinese real estate enterprises is ***,the proposed framework combines proportional hesitant fuzzy linguistic term sets and preference ranking organization method for enrichment evaluation II *** approach is suitable for processing large amounts of data with high uncertainty,which is often the case in credit risk assessment tasks of Chinese real estate enterprises involving massive subjec-tive evaluation ***,the proposed model is validated through a case study accompanied by sensitivity and comparative analyses to verify its rationality and *** study contributes to the research on credit assessment for Chinese real estate enterprises and provides a revised paradigm for real estate enterprise credit risk assessment.

关键词： Real estate enterprise Credit risk assessment PROMETHEE II Best–worst method Proportional hesitant fuzzy linguistic term sets

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