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Substance use and inhalation injury in adult burn patients:retrospective study of the impact on outcomes

Burns & Trauma 2019年第1期7卷 132-138页

作者： Kevin M.Klifto luis quiroga C.Scott Hultman Department of Plastic and Reconstructive Surgery Johns Hopkins Burn CenterThe Johns Hopkins Hospital4940 Eastern AvenueBaltimore 21224USA

Background:Substance use,alcohol use,and smoking use have all been associated with burn *** studies have investigated associations with substances,alcohol,smoking,inhalational only burns,and patient *** purpose of the study was to identify risk factors for pulmonary failure in patients suffering inhalation injury,focusing on the impact of substance,alcohol,and cigarette ***:This is a single-center retrospective analysis of 115 patients admitted to the Johns Hopkins Bayview Burn Center with inhalational injury from January 1,2010,through September 30,*** were excluded if they were under the age of 18 years or had burn involvement of the skin>5%.Primary outcome variables measured were if patients were intubated,length of total time intubated,substance use,alcohol use,and smoking *** outcome variables measured were types of substances used(amphetamines,barbiturates,benzodiazepines,cannabinoids,cocaine,methadone,codeine/morphine),total number of substances used,intensive care unit(ICU)length of stay(LOS),hospital LOS,secondary complications,and patient *** was performed with Fisher’s exact test and the Mann-Whitney U test.A sub-group analysis for each substance,alcohol,smoking,and control subgroup was compared to its respective sub-group without substance,alcohol,smoking,and control within the no intubation and intubation group.A sub-group analysis of substance use,alcohol use,smoking use,and control was further analyzed with binomial logistic regression within the intubation ***:Following inhalation injury,50/115(43%)patients required ***-two of the 50(84%)patients intubated had substance use(p<0.001).Thirty-one of the 50(62%)patients intubated had history of smoking(p=0.038).Among the specific substances used,26/50(52%)patients intubated were using benzodiazepines(p<0.001)and 7/50(14%)patients were using cocaine(p=0.022).The lengths of intubation,ICU LOS,and hospital LOS with no substanc

关键词： Intubation Smoking Burn Risk factors Cocaine Benzodiazepines Morphine Inhalation

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Microbial oxidation of refractory gold sulfide concentrate by a native consortium

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Transactions of Nonferrous Metals Society of China 2017年第5期27卷 1143-1149页

作者： N. MARCHEVSKY M. M. BARROSO quiroga A. GIAVENO E. DONATI Centro de Investigación y Desarrollo en Fermentaciones Industriales (CINDEFI CCT LA PLATA-CONICETUNLP) Facultad de Ciencias Exactas Universidad Nacional de La Plata Calle 50 N° 227 1900 La Plata Argentina Departamento de Minería Facultad de Ciencias Físico-Matemáticas y Naturales Universidad Nacional de San Luis Chacabuco 917 5700 San Luis Argentina Instituto de Investigación y Desarrollo en Ingeniería de Procesos Biotecnología y Energías Alternativas (PROBIEN CONICET-UNCo) Departamento de Química Facultad de Ingeniería Universidad Nacional del Comahue Buenos Aires 1400 8300 Neuquén Argentina

A defined mesophilic consortium including an iron oxidizing bacterium and a sulfur oxidizing bacterium was constructed to evaluate its ability for bioleaching a flotation concentrate from Andacollo mine in Neuquén,*** were performed in shake flasks with a pulp density of10%(w/v),using a basal salt medium containing ferrous iron at *** leaching solutions were analyzed for pH,redox potential(using specifics electrodes),ferrous iron(by UV-Vis spectrophotometry)and metal concentrations(by atomic absorption spectroscopy).The results showed that the consortium was able to reduce the refractory behavior of the concentrate,allowing91.6%of gold recovery;at the same time,high dissolution of copper and zinc was *** dissolutions followed a shrinking core kinetic *** to this model,the copper solubilization was controlled by diffusion through a product layer(mainly jarosite),while zinc dissolution did not show a defined control *** designed consortium,composed of bacterial strains with specific physiological abilities,could be useful not only to optimize gold recovery but also to decrease the leachates metallic charge,which would be an environmental advantage.

关键词： biooxidation refractory gold concentrate native consortium kinetic analysis

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