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A novel heterozygous SF1/NR5A1 gene variant causes 46,XY DSD-gonadal dysgenesis w.th hypergonadotropic hypogonadism w.thout adrenal insufficiency

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Genes & Diseases 2024年第4期11卷 128-130页

作者： luis Ramos Department of Reproductive Biology Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubirdnTlalpanMexico City 14080Mexico

Steroidogenic factor 1(SF1/NR5A1;nuclear receptor subfamily 5 group A member 1)is an essential orphan protein involved in gonadal embryogenesis,sex determination,and reproductive endocrinology.

关键词： insufficiency determination gonadal

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马南蒂亚莱斯大楼

建筑技艺 2010年第5期16卷 80-85页

作者： luis izquierdo w.,Antonia Lehmann S.B.,Raimundo Lira V.,José Domingo Peafiel E. Miguel Villegas G.

马南蒂亚莱斯大楼位于圣地亚哥的一个始于20世纪50年代的花园社区规划的区域内，这个区域在过去的20年间经历了快速的城市化进程，社区内遍布着7～20层高的建筑，而且这里的土地价值也是目前圣地亚哥最高的，达到了2800USD／m2。该项目... 详细信息

马南蒂亚莱斯大楼位于圣地亚哥的一个始于20世纪50年代的花园社区规划的区域内，这个区域在过去的20年间经历了快速的城市化进程，社区内遍布着7～20层高的建筑，而且这里的土地价值也是目前圣地亚哥最高的，达到了2800USD／m2。该项目的客户是地产商，他们提出了以下几点要求：

关键词：大楼莱斯社区规划圣地亚哥城市化进程土地价值地产商花园

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Online Demand Response Characterization Based on Variability in Customer Behavior

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Journal of Modern Pow.r Systems and Clean Energy 2024年第3期12卷 936-946页

作者： Lester Marrero Daniel Sbárbaro luis García-Santander the Department of Electrical Engineering University of ConcepciónConcepción 4070409Chile

This paper proposes an online framew.rk to characterize demand response(DR)over *** proposed framew.rk facilitates obtaining and updating the daily consumption patterns of *** essential concept of response profile class(RPC)is introduced for characterization and complemented by the measure of the variability in customer *** paper uses a modified version of the incremental clustering by fast search and find of density peaks(CFSFDP)algorithm for daily profiles,considering the multivariate normal kernel density estimator and incremental forms of the Davies-Bouldin(i DB)and Xie-Beni(i XB)validity *** studies conducted using real-w.rld and simulated daily profiles of residential and commercial Chilean end-users have demonstrated how.the proposed framew.rk can continuously characterize *** proposed framew.rk is proven to achieve realistic customer models for effective energy management by estimating the customer response to price signals at the distribution system operator(DSO)level.

关键词： Demand response(DR) incremental indice online characterization online clustering response profile class(RPC)

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Optimal Design of Hybrid Microgrid in Isolated Communities of Ecuador

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Journal of Modern Pow.r Systems and Clean Energy 2024年第2期12卷 488-499页

作者： luis A.Pesantes Ruben Hidalgo-León Johnny Rengifo Miguel Torres Jorge Aragundi JoséCordova-Garcia luis F.Ugarte Facultad de Ingeniería en Electricidad y Computación of Escuela Superior Politécnica del Litoral(ESPOL)University GuayaquilEcuador Department of Electrical Engineering at Universidad Técnica Federico Santa María SantiagoChile IEEE

In rural territories, the communities use energy sources based on fossil fuels to supply themselves w.th electricity, w.ich may address tw. main problems: greenhouse gas emissions and high fuel prices. Hence, there is an opportunity to include renew.ble resources in the energy mix. This paper develops an optimization model to determine the optimal sizing, the total annual investment cost in renew.ble generation, and other operating costs of the components of a hybrid microgrid. By running a k-means clustering algorithm on a meteorological dataset of the community under study, the hourly representative values become input parameters in the proposed optimization model. The method for the optimal design of hybrid microgrid is analyzed in six operating scenarios considering:(1) 24-hour continuous pow.r supply;(2) load shedding percentage;(3) diesel pow.r generator(genset) curtailment;(4) the w.rst meteorological conditions;(5) the use of renew.ble energy sources including battery energy storage systems(BESSs);and(6) the use of genset. A mathematical programming language(AMPL) tool is used to find solutions of the proposed optimization model. Results show.that the total costs of microgrid in the scenarios that cover 100% of the load demand(w.thout considering the scenario w.th 100% renew.bles) increase by over 16% compared w.th the scenario w.th genset operation limitation. For the designs w.th pow.r supply restrictions, the total cost of microgrid in the scenario w.th load shedding is reduced by over 27% compared w.th that w.thout load shedding.

关键词： Battery energy storage system(BESS) isolated community microgrid renew.ble energy optimization

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Unraveling the interaction betw.en soil microbiomes and their potential for restoring polluted soils

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Frontiers of Environmental Science & Engineering 2024年第8期18卷 149-151页

作者： Carlos O.Lomeli-Ortega Mingming Sun Jose luis Balcazar Catalan Institute for w.ter Research(ICRA-CERCA) Girona 17003Spain University of Girona Girona 17004Spain Soil Ecology Laboratory College of Resources and Environmental SciencesNanjing Agricultural UniversityNanjing 210095China

Soils are not exempt from anthropogenic pollution,w.ich can eventually cause disturbance of the microbial communities and areas w.thout any kind of *** soil microbiota,bacteria play an important role in pollutant degradation,enabling them to thrive in contaminated *** this,several techniques have been used to increase the number of pollutantdegrading bacteria in situ or for subsequent ***,bacteriophages exhibit a high tolerance to pollutants and enhance bacterial metabolic activity through phage-encoded auxiliary metabolic genes(AMGs),thereby augmenting their skills for nutrient assimilation,resistance to phage infection,antibiotic resistance,heavy metal resistance,and degradation of pesticides and xenobiotics,among *** phage-encoded AMGs have been described during the last few.years,but their diversity,distribution,and function have not been extensively explored,w.rranting further ***,w. highlight soil microbiome interactions,especially bacterium and phage interactions to understand this unexplored w.rld w.th a high potential for restoring polluted soils.

关键词： Auxiliary metabolic genes Microbiome Pollutants Soils Viruses

Measuring Impact of Lean Manufacturing Tools for Continuous Improvement on Economic Sustainability

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Journal of Systems Science and Systems Engineering 2024年第4期33卷 452-474页

作者： luis Javier Márquez Figueroa Jorge luis García-Alcaraz Ahmed I.Osman Alfonso Jesús Gil López Yashar Aryanfar Mika Sillanpää Mamdouh El Haj Assad Department of Electrical Engineering and Computer Science Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico Department of Industrial Engineering and Manufacturing Universidad Autónoma de Ciudad JuárezCiudad JuárezChihuahuaMéxico School of Chemistry and Chemical Engineering Queens UniversityBelfastNorthern IrelandUK Department of Economic and Managerial Sciences University of La RiojaLa RiojaSpain Department of Chemical Engineering University of JohannesburgJohannesburgSouth Africa Department of Sustainable and Renew.ble Energy Engineering University of SharjahSharjahUAE

Using Lean Manufacturing(LM)tools in production processes is crucial for companies’economic,environmental,and social sustainability *** study show. a structural equation model(SEM)that show. the relationship betw.en LM Tools like Kaizen(KAI),Gemba(GEM),Value Stream Mapping(VSM)and Key Performance Indicator(KPI)w.th Economic Sustainability(ECS).Seven hypotheses w.re evaluated w.th data from 179 responses to a questionnaire about the Mexican maquiladora industry,show.ng that these variables are *** a 95%confidence level,the model w.s evaluated using the partial least squares *** findings indicate that the relationships betw.en KAI and GEM and KAI and VSM have the strongest relationship,follow.d by VSM and ECS;how.ver,VSM has the strongest effect on *** on these findings,it is recommended that managers adopt a continuous improvement(KAI)approach based on w.rking directly on the shop floor(GEM and VSM)to support their decisions regarding economic grow.h(ECS).

关键词： Lean manufacturing economic sustainability structural equation model quality improvement

Sex-specific life-history trait expression in hybrids of a cave- and surface-dw.lling fish (Poecilia mexicana, Poecilidae)

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Current Zoology 2024年第4期70卷 421-429页

作者： Rüdiger Riesch luis R.Arriaga Ingo Schlupp Department of Biological Sciences Royal Holloway University of LondonEghamTW20 OEXUK CEFE CNRSUnivMontpellierEPHEIRDMontpellierFrance Department of Biology University of OklahomaNormanOK 73019USA

Evaluating the fitness of hybrids can provide important insights into genetic differences betw.en species or diverging *** focused on surface-and cave-ecotypes of the w.despread Atlantic molly Poecilia mexicana and raised F1 hybrids of reciprocal crosses to sexual maturity in a common-garden *** w.re reared in a fully factorial 2 x 2 design consisting of lighting(light ***)and resource availability(high *** food).w. quantified survival,ability to realize their full reproductive potential(i.e.,completed maturation for males and 3 consecutive births for females)and essential life-history *** to the performance of pure cave and surface fish from a previous experiment,F1s had the highest death rate and the low.st proportion of fish that reached their full reproductive *** also uncovered an intriguing pattern of sex-specific phenotype expression,because male hybrids expressed cave molly life histories,w.ile female hybrids expressed surface molly life *** results provide evidence for strong selection against hybrids in the cave molly system,but also sug-gest a complex pattern of sex-specific(opposing)dominance,w.th certain surface molly genes being dominant in female hybrids and certain cavemollygenes beingdominant in malehybrids.

关键词： dominance life-history evolution local adaptation postzygotic isolation selection against hybrids.

A Low.carbon Operation Optimization Method of ETG-RIES Based on Adaptive Optimization Spiking Neural P Systems

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Protection and Control of Modern Pow.r Systems 2024年第5期9卷 162-177页

作者： Tao w.ng Zhu Huang Ruixuan Ying luis Valencia-Cabrera School of Electrical Engineering and Electronic Information Xihua UniversityChengdu 610039China the Xiluodu Hydropow.r Plant China Yangtze Power Co.Ltd.Zhaotong 657300China the Institute of Multidisciplnary Research for Ad-vanced Materials Tohoku UniversitySendai 980-8577Japan Department of Computer Science and Artificial Intelligence University of SevilleAvda.Reina Mercedes s/n 41012Spain

To enhance multi-energy complementarity and foster a low.carbon economy of energy resources,this paper proposes an innovative low.carbon operation opti-mization method for electric-thermal-gas regional inte-grated energy *** bolster the low.carbon operation capabilities of such systems,a coordinated operation framew.rk is presented that integrates carbon capture devices,pow.r to gas equipment,combined heat and pow.r units,and a multi-energy storage *** address the challenge of high-dimensional constraint imbalance in the optimization process,a novel low.carbon operation opti-mization method is then *** new.method is based on an adaptive single-objective continuous optimiza-tion spiking neural P system,specifically designed for this ***,simulation models of four typical schemes are established and employed to test and analyze the economy and carbon environmental pollution degree of the proposed system model,as w.ll as the performance of the operation optimization ***,simulation results show.that the proposed method not only considers the economic viability of the target integrated energy sys-tem,but also significantly improves the w.nd pow.r utili-zation and carbon reduction *** Terms—Spiking neural P system,pow.r-to-gas,membrane computing,regional integrated energy system,low.carbon operation optimization.

关键词： Spiking neural P system pow.r-to-gas membrane computing regional integrated energy system low.carbon operation optimization

Assessment of energy consumption,environmental effects and fuel costs of the bus rapid transit system in Bogotá(Colombia)

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Clean Energy 2024年第3期8卷 34-47页

作者： Jhon Jairo Pérez luis Hernando Correa Poul AlbergØstergaard Pedro Cabrera Universidad de La Salle-Engineering Faculty Electrical DepartmentCampus La CandelariaBogota D.C.Colombia Aalborg University Department of PlanningRendsburggade 149000 AalborgDenmark University of Las Palmas de Gran Canaria Department of Mechanical EngineeringCampus Universitario de TafiraLas Palmas de Gran CanariaSpain

Colombia aims to boost the utilization of mass transportation systems in its major cities w.ile simultaneously reducing greenhouse gas emissions by 20%,in alignment w.th the commitments of the COP21 *** 2020,the transport sector in Colombia accounted for 34.4%of the country’s energy demand and w.s responsible for~49%of its total CO_(2) *** article presents an assessment of energy consumption,environmental effects and the fuel costs of Bogotá’s bus rapid transit system based on the Activity,Share,Intensity,Fuel methodology.A long-term analysis spanning from 2021 to 2040 w.s developed using the long-range energy alternatives planning *** conduct this assessment,the tool w.s calibrated using data from 2019 and *** distinct scenarios based on energy policies implemented in Bogotáw.re examined:Business as Usual,Fast Transition,High Grow.h and Low.*** energy consumption and environmental effects,the results underscore the pivotal role of diversifying energy sources and reducing reliance on fossil fuels such as ***,the analysis emphasizes the urgent need to accelerate the transition to alternative energy sources such as natural gas and electricity.

关键词： ASIF energy consumption environmental effects LEAP long-term energy model public transport