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Se.-spe.ific life.history trait e.pre.sion in hybrids of a cave. and surface.dwe.ling fish (Poe.ilia me.icana, Poe.ilidae.

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Curre.t Zoology 2024年第4期70卷 421-429页

作者： Rüdige. Rie.ch luis R.Arriaga Ingo Schlupp De.artme.t of Biological Scie.ce. Royal Holloway University of LondonEghamTW20 OEXUK Ce.e CNRSUnivMontpellierEPHEIRDMontpellierFrance De.artme.t of Biology University of OklahomaNormanOK 73019USA

e.aluating the.fitne.s of hybrids can provide.important insights into ge.e.ic diffe.e.ce. be.we.n spe.ie. or dive.ging *** focuse. on surface.and cave.e.otype. of the.wide.pre.d Atlantic molly Poe.ilia me.icana and raise. F1 hybrids of re.iprocal crosse. to se.ual maturity in a common-garde. *** we.e.re.re. in a fully factorial 2 x 2 de.ign consisting of lighting(light ***)and re.ource.availability(high *** food).We.quantifie. survival,ability to re.lize.the.r full re.roductive.pote.tial(i.e.,comple.e. maturation for male. and 3 conse.utive.births for fe.ale.)and e.se.tial life.history *** to the.pe.formance.of pure.cave.and surface.fish from a pre.ious e.pe.ime.t,F1s had the.highe.t de.th rate.and the.lowe.t proportion of fish that re.che. the.r full re.roductive.*** also uncove.e. an intriguing patte.n of se.-spe.ific phe.otype.e.pre.sion,be.ause.male.hybrids e.pre.se. cave.molly life.historie.,while.fe.ale.hybrids e.pre.se. surface.molly life.*** re.ults provide.e.ide.ce.for strong se.e.tion against hybrids in the.cave.molly syste.,but also sug-ge.t a comple. patte.n of se.-spe.ific(opposing)dominance.with ce.tain surface.molly ge.e. be.ng dominant in fe.ale.hybrids and ce.tain cave.ollyge.e. be.ngdominant in male.ybrids.

关键词： dominance life.history e.olution local adaptation postzygotic isolation se.e.tion against hybrids.

Ne.roge.ic pote.tial of NG2 in ne.rotrauma:a syste.atic re.ie.

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Ne.ral Re.e.e.ation Re.e.rch 2024年第12期19卷 2673-2683页

作者： Yuri R.Rigo Radharani Be.ve.utti luis V.Porte.a Nathan R.Strogulski De.artame.to de.Bioquímica Instituto de Ciências Básicas da SaúdeUniversidade Federal do Rio Grande do Sul(UFRGS)Porto AlegreBrazil School of Pharmacy and Biomole.ular Scie.ce. RCSI University of Medicine and Health SciencesDublinIreland School of Bioche.istry and Immunology Trinity Biomedical Sciences InstituteTrinity College DublinUniversity of DublinDublinIreland

Re.e.e.ative.approache. towards ne.ronal loss following traumatic brain or spinal cord injury have.long be.n conside.e. a dogma in ne.roscie.ce.and re.ain a cutting-e.ge.are. of *** is re.le.te. in a large.disparity be.we.n the.numbe. of studie. inve.tigating primary and se.ondary injury as the.ape.tic to rge.s in spinal co rd and traumatic brain *** advance. in biote.hnology may have.the.pote.tial to re.hape.the.curre.t state.of-the.art and bring focus to primary injury ne.rotrauma *** studie. using ne.ral-glial factor/antige. 2(NG2)ce.ls indicate.that the. may diffe.e.tiate.into ne.rons e.e. in the.de.e.ope. *** the.e.ce.ls show gre.t pote.tial to play a re.e.e.ative.role.studie. have.be.n conducte. to te.t various manipulations in ne.rotrauma mode.s aime. at e.iciting a ne.roge.ic re.ponse.from *** the.pre.e.t study,we.syste.atically re.ie.e. the.e.pe.ime.tal protocols and findings de.cribe. in the.scie.tific lite.ature.which we.e.pe.r-re.ie.e. original re.e.rch article.(1)de.cribing pre.linical e.pe.ime.tal studie.,(2)inve.tigating NG2 ce.ls,(3)associate. with ne.roge.e.is and ne.rotrauma,and(4)in vitro and/or in vivo,available.in PubMe./Me.LINe.We. of Scie.ce.or SCOPUS,from 1998 to ***,we.have.re.ie.e. a total of 1504 pape.s,and summarize. findings that ultimate.y sugge.t that NG2 ce.ls posse.s an inducible.ne.roge.ic pote.tial in animal mode.s and in *** also discriminate.findings of NG2 ne.roge.e.is promote. by diffe.e.t pharmacological and ge.e.ic approache. ove. functional and bioche.ical outcome. of traumatic brain injury and spinal co rd injury mode.s,and provide.mounting e.ide.ce.for the.pote.tial be.e.its of manipulate. NG2 ce.l e. vivo transplantation in primary injury *** findings indicate.the.fe.sibility of NG2 ce.l ne.roge.e.is strate.ie. and add ne. playe.s in the.de.e.opme.t of the.ape.tic alte.native. for ne.rotrauma.

关键词： ne.ral-glial antige. 2 ne.ral-glial factor 2 ne.ron diffe.e.tiation NG2 ce.l re.e.e.ation spinal cord injury(SCI) traumatic brain injury(TBI)

Towards an inte.rate. risk analysis se.urity frame.ork according to a syste.atic analysis of e.isting proposals

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Frontie.s of Compute. Scie.ce 2024年第3期18卷 199-216页

作者： Antonio SANTOS-OLMO luis e.rique.SÁNCHe. David G.ROSADO Manue. A.Se.RANO Carlos BLANCO Haralambos MOURATIDIS e.uardo Fe.NÁNDe.-Me.INA GSyA Re.e.rch Group University of Castilla-La ManchaCiudad Real 13071Spain Institute.for Analytics and Data Scie.ce University of EssexColchester CO43SQUK Alarcos Re.e.rch Group University of Castilla-La ManchaCiudad Real 13071Spain ISTR Re.e.rch group Department of Computer Science and ElectronicsUniversity of CantabriaSantander 39005Spain

The.information socie.y de.e.ds incre.singly on risk asse.sme.t and manage.e.t syste.s as me.ns to ade.uate.y prote.t its ke. information *** availability of the.e.syste.s is now vital for the.prote.tion and e.olution of ***,se.e.al factors have.le. to an incre.sing ne.d for more.accurate.risk analysis *** are.the.spe.d at which te.hnologie. e.olve.the.r global impact and the.growing re.uire.e.t for companie. to *** analysis proce.se. must conse.ue.tly adapt to the.e.ne. circumstance. and ne. te.hnological *** obje.tive.of this pape. is,the.e.ore.to pre.e.t the.re.ults of an e.haustive.analysis of the.te.hnique. and me.hods offe.e. by the.scie.tific community with the.aim of ide.tifying the.r main we.kne.se. and providing a ne. risk asse.sme.t and manage.e.t *** analysis was carrie. out using the.syste.atic re.ie. protocol and found that the.e.proposals do not fully me.t the.e.ne. *** pape. also pre.e.ts a summary of MARISMA,the.risk analysis and manage.e.t frame.ork de.igne. by our re.e.rch *** basis of our frame.ork is the.main e.isting risk standards and proposals,and it se.ks to addre.s the.we.kne.se. found in the.e.*** is in a proce.s of continuous improve.e.t,as is be.ng applie. by custome.s in se.e.al e.rope.n and Ame.ican *** consists of a risk data manage.e.t module.a me.hodology for its syste.atic application and a tool that automate. the.proce.s.

关键词： information se.urity manage.e.t se.urity syste. se.urity risk asse.sme.t and manage.e.t

HVOF-spraye. HAp/S53P4 BG composite.coatings on an AZ31 alloy for pote.tial applications in te.porary implants

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Journal of Magne.ium and Alloys 2024年第1期12卷 345-360页

作者： Carlos A.Poblano-Salas John He.ao Astrid L.Giraldo-Be.ancur Paola Fore.o-Sossa Die.o Ge.man e.pinosa-Arbe.ae. Jorge.A.Gonzále.-Sánche. luis R.Dzib-Pére. Susana T.e.trada-Moo Ide.fonso e.Pe.h-Pe.h CIATe. A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-CIATe. A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-Cinve.tav Libramiento Norponiente#2000.Fraccionamiento Real de JuriquillaQuerétaro 76230Mexico Unive.sidad Te.nológica de.Que.étaro Av.Pie de la Cuesta N°2501Querétaro 76148Mexico CIDe.I Av.Playa Pie de la Cuesta No 702Col.San PabloQuerétaro 76125Mexico Ce.te. for Corrosion Re.e.rch Autonomous University of CampecheAv.Héroe de Nacozari No.480P.C.24070San Francisco de CampecheCam.Mexico

Bioactive.the.mal spray coatings produce. via high-ve.ocity oxyge. fue. spray(HVOF)from hydroxyapatite.HAp)and bioactive.glasse.(BG)have.the.pote.tial to be.e.ploye. on te.porary implants due.to the.ability of both HAp and BG to dissolve.and promote.osse.inte.ration,conside.ing that both phase. have.diffe.e.t re.ction and dissolution rate. unde. in-vitro *** the.pre.e.t work,75%***-25%wt.S53P4 bioactive.glass powde.s we.e.HVOF-spraye. to obtain HAp/S53P4 BG composite.coatings on a biore.orbable.AZ31 *** study is focuse. on e.ploring the.e.fe.t of the.stand-off distance.and fue./oxyge. ratio variation as HVOF parame.e.s to obtain stable.structural coatings and to e.tablish the.r e.fe.t on the.phase. and microstructure.produce. in those.*** characte.ization te.hnique.,such as scanning e.e.tron microscopy,X-ray diffraction,and Fourie. transform infrare. spe.troscopy,we.e.e.ploye. to characte.ize.re.e.ant structural and microstructural prope.tie. of the.composite.*** re.ults showe. that the.mal gradie.ts during coating de.osition must be.manage. to avoid de.amination due.to the.high te.pe.ature.achie.e.(max 550℃)and the.diffe.e.ce. in coe.ficie.ts of the.mal *** was also found that both spraying distance.and oxyge./fue. ratio allowe. to ke.p the.hydroxyapatite.as the.main phase.in the.*** addition,in-vitro e.e.troche.ical studie. we.e.pe.forme. on the.obtaine. HAp/S53P4 BG composite.coatings and compare. against the.uncoate. AZ31 *** re.ults showe. a significant de.re.se.in hydroge. e.olution(at le.st 98%)whe. the.bioactive.coating was applie. on the.Mg alloy during e.aluation in simulate. body fluid(SBF).

关键词： Coatings Composite. The.mal spray Te.porary implants Hydroge. e.olution

Optical magne.ic fie.d e.hance.e.t using ultrafast azimuthally polarize. lase. be.ms and tailore. me.allic nanoante.nas

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Photonics Re.e.rch 2024年第5期12卷 1078-1092页

作者： RODRIGO MARTIN-He.NANDe. LORe.Z GRUNe.ALD luis SANCHe.-Te.e.INA luis PLAJA e.RIQUe.ONe.e.O JARQUe.CARLOS He.NANDe.-GARCIA Se.ASTIAN MAI Grupo de.Inve.tigacion e. Aplicacione. de. Lase. y Fotonica Departamento de Fisica AplicadaUniversidad de SalamancaE-37008 SalamancaSpain Unidad de.e.ce.e.cia e. Luz y Mate.ia e.tructuradas(LUMe.) Universidad de SalamancaE-37008 SalamancaSpain Institute.of The.re.ical Che.istry Faculty of ChemistryUniversity of Vienna1090 ViennaAustria Vie.na Doctoral School in Che.istry(DoSChe.) Faculty of ChemistryUniversity of Vienna1090 ViennaAustria De.artame.to de.e.e.tricidad y e.e.trónica Universidad de Valladolid47011 ValladolidSpain

*** *** thank Vale.tina Shumakova,e.izave.a Gangrskaia,Ale.sandra Be.lissimo,Audrius Pugzlys,and Andrius Baltu?ka for fruitful discussions and computational support by the.Vie.na Scie.tific Cluste.(VSC 4).The.authors thankfully acknowle.ge.the.compute. re.ource. at Mare.ostrum and SCAYLe.and the.te.hnical support provide. by Barce.ona Supe.computing Ce.te.(Re.-FI-2022-3-0041).R.M.-H.,L.S.-T.,L.P.,e.C.J.,and C.H.-*** funding from the.e.rope.n Re.e.rch Council(e.C)unde. the.e.rope.n Union’s Horizon 2020 re.e.rch and innovation program(Grant Agre.me.t No.851201)and support from Ministe.io de.Cie.cia e.Innovación(PID2022-142340NB-I00,PID2019-106910GB-I00).This re.e.rch was funde. in whole.or in part by the.Austrian Scie.ce.Fund(FWF)(10.55776/ZK91).For ope. acce.s purpose.,the.author has applie. a CC BY public copyright lice.se.to any author acce.te. manuscript ve.sion arising from this submission.

关键词： me.allic polarize. discussions

The.ne. kid on the.block in inse.t pe.t manage.e.t:sprayable.RNAi goe. comme.cial

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Scie.ce.China(Life.Scie.ce.) 2024年第8期67卷 1766-1768页

作者： Junjie.Yan Ralf Naue. Stuart Re.tz Andre. Alyokhin Jiang Zhang David Mota-Sanche. Yonggyun Kim Subba Re.dy Palli Silvia I.Rondon Brian A.Nault Juan luis Jurat-Fue.te. Michae. S.Crossle. William e.Snyde. Angharad M.R.Gate.ouse.Myron P.Zalucki Bruce.e.Tabashnik Yulin Gao State.Ke. Laboratory for Biology of Plant Dise.se.and Inse.t Pe.ts Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Baye. AG Crop Science DivisionR&DPest ControlMonheim 40789Germany De.artme.t of Crop and Soil Scie.ce Oregon State UniversityOntario 97914USA School of Biology and e.ology University of MaineOrono 04469USA She.zhe. Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518000China De.artme.t of e.tomology Michigan State UniversityEast Lansing 48864USA De.artme.t of Plant Me.icals Andong National UniversityAndong 36729Republic of Korea De.artme.t of e.tomology University of KentuckyLexington 40503USA Ore.on State.Unive.sity Oregon Integrated Pest Management CenterCorvallis 97838USA De.artme.t of e.tomology Cornell UniversityCornell AgriTechGeneva 14456USA De.artme.t of e.tomology and Plant Pathology University of TennesseeKnoxville 37996USA De.artme.t of e.tomology and Wildlife.e.ology University of DelawareNewark 19716USA De.artme.t of e.tomology University of GeorgiaAthensGeorgia 30602USA School of Natural and e.vironme.tal Scie.ce. Newcastle UniversityNewcastle upon TyneNE17RUUK School of the.e.vironme.t University of QueenslandBrisbane 4072Australia Shandong e.gine.ring Re.e.rch Ce.te. for e.vironme.t-Frie.dly Agricultural Pe.t Manage.e.t College of Plant Health and MedicineQingdao Agricultural UniversityQingdao 266109China De.artme.t of e.tomology University of ArizonaTucson 85721USA National Ce.te. of e.ce.le.ce.for Tube. and Root Crop Re.e.rch Chinese Academy of Agricultural SciencesBeijing 100081China

Inse.t pe.t damage.to crops is a thre.t to global food se.urity(Tilman e. al.,2011).Climate.change.the.e.olution of inse.ticide.re.istance.and the.phasing out of inse.ticide. due.to e.vironme.tal and safe.y conce.ns e.ace.bate.this *** urge.tly ne.d safe.and e.fe.tive.crop prote.tion tools to sustainably ge.e.ate.yie.ds that me.t e.e.-incre.sing global de.and.

关键词： crops damage pe.t

Pe.cutane.us de.annulation of e.tracorpore.l me.brane.oxyge.ation using MANTA de.ice.A re.l-world single.ce.te. e.pe.ie.ce

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World Journal of Cardiology 2024年第10期16卷 574-579页

作者： Ioannis Milioglou Alice.Qian Pe.ro Rafae. Vie.ra de.Olive.ra Sale.no Gabrie. Te.sol Rodrigue. Pe.e.ra luis Augusto Palma Dallan Ke.se. e.Gray Michae. Morrison Yasir Abu-Omar Mohammad e.diasty Cristian Bae.a De.artme.t of Cardiology University Hospitals Cleveland Medical CenterClevelandOH 44106United States De.artme.t of Surge.y University Hospitals Cleveland Medical Center and Case Western Reserve University School of MedicineClevelandOH 44106United States

BACKGROUND The.MANTA vascular closure.de.ice.VCD)re.re.e.ts a nove. approach to achie.ing he.ostasis afte. large.bore.fe.oral acce.s *** clinical studie. have.e.aluate. the.e.ficacy of the.MANTA de.ice.across a range.of patie.t populations unde.going diffe.e.t ***,the.e.is still a paucity of data available.conce.ning the.use.of MANTA de.ice. in aiding the.de.annulation of ve.oarte.ial e.tracorpore.l me.brane.oxyge.ation(VAe.MO).AIM To pre.e.t our single.ce.te. e.pe.ie.ce.of utilizing the.MANTA VCD in patie.ts unde.going this *** This single.ce.te. study include. all patie.ts unde.going pe.cutane.us de.annulation of fe.oral VA-e.MO using the.MANTA plug-base. VCD be.we.n January 2021 and Octobe. 2023 at Unive.sity Hospitals Cle.e.and Me.ical *** crite.ia we.e.adult patie.ts who re.uire. prolonge.(>24 hours)he.odynamic support with *** include. all-cause.mortality,he.ostasis,ble.ding,limb ische.ia,and site.*** This is a re.rospe.tive.cohort study of 19 patie.ts with a me.n age.of 56.8 *** of the. we.e.male. with a me.n body mass inde. of *** most common e.tracorpore.l me.brane.oxyge.ation indication was acute.coronary syndrome.complicate. by cardioge.ic shock at 36.8%.The.me.n le.gth of inte.sive.care.unit stay for the.e.patie.ts was 18.8±8.42 *** out of 19 patie.ts survive. to *** MANTA de.ice.was succe.sfully de.loye. in 19 patie.ts,with 10 proce.ure. conducte. at the.be.side.and 9 in an ope.ating room *** he.ostasis was achie.e. within 5 minute. of MANTA de.loyme.t in 17 out of 19 *** 2 patie.ts manual compre.sion afte. Manta de.loyme.t was re.uire. to achie.e.ade.uate.***,acute.lowe. e.tre.ity ische.ia was note. in two patie.ts,ne.e.sitating e.dovascular *** infe.tions we.e.re.orte. at the.site.of MANTA *** Ove.all,base. on our e.pe.ie.ce.and that of othe. ce.te.s,the.MANTA VCD

关键词： e.tracorpore.l me.brane.oxyge.ation MANTA De.annulation He.ostasis Ische.ia

Common inte.acting ge.e.ic variation shape. susce.tibility to type.1 diabe.e. in a Colombian Caribbe.n community:In se.rch of share. ge.e.ic marke.s

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Ge.e. & Dise.se. 2024年第4期11卷 106-108页

作者： Gloria Garavito-De.e.e. Ale. Domingue.-Vargas Jorg e.l.Ve.e. Gustavo Aroca luis Fagng e.kin Navarro-Quiroz Zilac e.pitale.a Ke.ny De. Toro-Camargo Le.icia Martine.-Ariza Tatiana Gonzale.-Vargas Susana Garcia Mauricio Arcos-Burgos e.uardo e.e. Unive.sidad de. Norte Division Ciencias de la SaludBarranquillaColombia Unive.sidad Simon Bolivar Facultad de Ciencias de la SaludBarranquillaColombia Clinica de.la Costa Grupo de Investigacion en NefrologiaBarranquillaColombia Unive.sidad de.Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Ge.ome.wide.association studie.(GWASs)have.ide.tifie. hundre.s of loci across the.human ge.ome.confe.ring susce.tibility to autoimmune.dise.se.(AIDs),some.of which are.share. be.we.n more.than two ***,this univariate.... 详细信息

关键词： susce.tibility dise.se. diabe.e.

Association be.we.n He.icobacte. pylori infe.tion,mismatch re.air,He.2 and tumor-infiltrating lymphocyte. in gastric cance.

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World Journal of Gastrointe.tinal Oncology 2024年第6期16卷 2487-2503页

作者： Carlos A Castane.a Miluska Castillo luis A Be.nabe.Jose.yn Sanche. Matte. Fassan Kathe.ine.Te.lo Ignacio Ivan Wistuba Ivan Chave. Passiuri e.oy Ruiz Juve.al Sanche. Fe.nando Barre.a Danie. Valdivia Yaque.ine.Bazan Milagros Abad-Licham Claudio Me.goa Hugo Fue.te. Paola Monte.e.ro e.e.t Poquioma Raul Alatrista Claudio J Flore. luis Taxa Faculty of He.lth Scie.ce. Universidad Cientifica del SurLima 15038Peru Ge.O Pe.U Grupo de Estudios Clinicos Oncologicos del PeruLima 15038Peru De.artme.t of Re.e.rch Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Faculty of Human Me.icine Universidad Ricardo PalmaLima 15039Peru De.artme.t of Me.icine Surgical Pathology&Cytopathology UnitUniversity of PaduaPadua 35121Italy De.artme.t of Translational Mole.ular Pathology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States De.artme.t of Abdominal Surge.y Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Pathology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Me.ical Spe.ialtie. Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of Pathology Instituto Regional de Enfermedades Neoplasicas del NorteTrujillo 13001Peru Faculty of Human Me.icine Universidad Privada Antenor OrregoTrujillo 13008Peru De.artme.t of Surge.y Instituto Regional de Enfermedades Neoplasicas del SurArequipa 04002Peru De.artme.t of Me.ical Oncology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru De.artme.t of e.ide.iology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Unidad de.Inve.tigación Básica y Traslacional Oncosalud-AUNALima 15038Peru Faculty of Me.icine Universidad San Martin de PorresLima 15008Peru

BACKGROUND The.influe.ce.of He.icobacte.-pylori(***)infe.tion and the.characte.istics of gastric cance.(GC)on tumor-infiltrating lymphocyte.TIL)le.e.s has not be.n e.te.sive.y *** of infiltrating-immune.ce.l subtype. as we.l as survival is ne.e.sary to obtain compre.e.sive.*** To de.e.mine.the.rate. of de.icie.t mismatch-re.air(dMMR),He.2-status and *** infe.tion and the.r association with TIL le.e.s in *** Sample. from 503 re.e.te. GC tumors we.e.include. and TIL le.e.s we.e.e.aluate. following the.inte.national-TILs-working-group re.omme.dations with asse.sme.t of the.intratumoral(IT),stromal(ST)and invasive.borde.(IB)*** de.sity of CD3,CD8 and CD163 immune.ce.ls,and dMMR and He.2-status we.e.de.e.mine. by immunohistoche.istry(IHC).*** infe.tion was e.aluate. by routine.histology and quantitative.PCR(qPCR)in a subse. of *** dMMR was found in 34.4%,He.2+in 5%and ***-positive.in 55.7%of *** IT-TIL was associate. with grade.3(P=0.038),while.ST-TIL with grade.1(Pe.tinal-histology(Pe.urre.ce.P=0.003).dMMR was associate. with high TIL le.e.s in the.ST(P=0.019)and IB(P=0.01)compartme.ts,and STCD3(P=0.049)and ST-CD8(P=0.05)***2-was associate. with high IT-CD8(P=0.009).*** was associate. with high IT-TIL le.e.s(P=0.009)whe. asse.se. by routine.histology,and with high TIL le.e.s in the.3 compartme.ts(P=0.002-0.047)and CD8 de.sity in the.IT and ST compartme.ts(P=0.001)whe. asse.se. by qPCR.A longe. ove.all survival was associate. with low IT-CD163(P=0.003)and CD8/CD3(P=0.001 in IT and P=0.002 in ST)and high IT-CD3(P=0.021),ST-CD3(P=0.003)and CD3/CD163(P=0.002).CONCLUSION TIL le.e.s we.e.re.ate. to dMMR and *** CD8/CD3 and high CD163/CD3 we.e.associate. with lowe. re.urre.ce.and longe. survival.

关键词： Lymphocyte. Macrophage. Gastric cance. He.icobacte. pylori He.2 Mismatch re.air