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用浸渍液相外延技术生长(Hg,Cd)Te

红外 1995年第11期16卷 6-12页

作者： luigi colombo 顾聚兴美国得克萨斯仪器公司中心研究实验室

通过液相外延技术从大量富碲溶液中生长(?)Hg,Cd)Te 厚层材料已被用来产生大量可制造焦平面列阵的高质量薄膜。在组分x=0.223的情况下,从43 cm^2至54 cm^2面积上测得的组分均匀性为△x=±0.001。在总面积超过8000cm^2的约200次生长过程... 详细信息

通过液相外延技术从大量富碲溶液中生长(?)Hg,Cd)Te 厚层材料已被用来产生大量可制造焦平面列阵的高质量薄膜。在组分x=0.223的情况下,从43 cm^2至54 cm^2面积上测得的组分均匀性为△x=±0.001。在总面积超过8000cm^2的约200次生长过程中,重复率为x=0.226±0.0033,相当于λ_(co)=9.85±0.44μm。用以制造二极管的材料的电学质量是通过生长n型薄膜并在背面进行约5×10^(14)cm^(-3)的铟掺杂而估计出来的。载流子浓度可以重复,而且与铟的掺杂水平完全相符。在77K处的平均载流子浓度为5.3±2.4×10^(14)cm^(-3),迁移率为1.31±0.3×10~5cm^2/Vs。n型薄膜的少数载流子寿命已达俄歇(Auger)限,其平均值为6.8±2.0μs。

关键词：液相外延汞镉碲薄膜半导体

Correction of hypovitaminosis D improved global longitudinal strain earlier than left ventricular ejection fraction in cardiovascular older adults after orthopaedic surgery

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Journal of Geriatric Cardiology 2018年第8期15卷 519-522页

作者： Matteo Briguglio luigi Gianturco Daniele Stellat Chiara colombo Marika Bonadies Oscar Salat Mauro Anselmi Giuseppe Banff Maurizio Turiel Cardiology Unit IRCCS Orthopaedic Institute Galeazzi Milan Italy Scientific Direction IRCCS Orthopaedic Institute Galeazzi Milan Italy University Vitae Salute San Raffaele Milan Italy

Background Cardiovascular diseases and insufficient levels of vitamin D are risk factors for adverse surgical outcomes, and they are both commonly present among older adults undergoing orthopaedic surgery. Giving the cardiovascular effects of vitamin D, pre-operative diagnosis of hypovitaminosis D would be a valuable step for the implementation of supplementation protocols. We investigated if the nor- malization of serum 25 [OH] D could ameliorate cardiac performance of older adults suffering from cardiovascular diseases. Methods We enrolled 47 older adults scheduled for major orthopaedic surgery and suffering from hypovitaminosis D. Patients underwent 6-months cal- cifediol supplementation with a starting dose at first post-operative day of 50 ~tg/die in liquid preparation. Down-titration to 20 Ixg/die at 3-months assessment was planned. Cardiac performance was evaluated by measuring left ventricular ejection fraction （LVEF） and global longitudinal strain （GLS） during pre-operative assessments and at 1-month, 3-months, 6-months follow-ups. Results Six months of cal- cifediol supplementation were associated with a significant improvement of both LVEF （＋ 3.94%; 95% CI： -4.0789 to -0.8232; P 〈 0.01） and GLS （＋ 18.56%; Z = -5.895; P 〈 0.0001）. Conclusions Calcifediol supplementation normalized serum 25 [OH] D concentration after 1-month treatment. GLS offered better insights into myocardial contractile amelioration than LVEF, thus being useful for detecting earlier subclinical changes that may anticipate hemodynamic modifications.

关键词： Global longitudinal strain Left ventricular ejection fraction Orthopedic surgery Transthoracic echocardiography Vitamin D

Innovative Metallized Formulations for Solid Rocket Propulsion

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含能材料 2012年第4期20卷 465-474页

作者： luigi T DeLUCA Luciano GALFETTI Filippo MAGGI Giovanni colombo Alice REINA Stefano DOSSI Daniele CONSONNI Melissa BRAMBILLA SPLab Dipartimento di Ingegneria AerospazialePolitecnico di MilanoI-20156 MilanItaly

Several metallized solid rocket propellants,AP/Metal/HTPB in the ratio 68/18/14,were experimentally analyzed at the Space Propulsion Laboratory of Politecnico di *** of the metals(micrometric and nanometric Al,B,Mg,and a variety of dual metals) on the performance of the propellant were studied and contrasted to a conventional micrometric aluminum(30 μm average grain size) taken as *** is shown that the propellant microstructure plays a fundamental role in controlling the critical aggregation/agglomeration phenomena occurring below and near the burning *** specific effects of microstructure in terms of steady burning rate and average agglomerate size are illustrated.

关键词： solid propellants metal powders combustion specific impulse burning rate agglomeration

On the emission lines in active galactic nuclei with relativistic jets

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Research in Astronomy and Astrophysics 2012年第4期12卷 359-368页

作者： luigi Foschini INAF-Osservatorio Astronomico di Brera Via E. Bianchi 46 23807 Merate (LC) Italy

The effect of the observed continuum emitted from a relativistic jet on the measurement of the full width at half maximum （FWHM） of an emission line is analyzed. If the jet contribution is not properly subtracted, the FWHM of the line could seem narrower than it should. The cases of an emission line detected in BL Lac objects and γ-ray Narrow-Line Seyfert 1 galaxies （γ-NLS1s） are addressed. It is shown that the smallness of the observed FWHM of the Lyα lines detected in three well-known BL Lacs is an effect due to the combined action of both the relativistic jet and a weak accretion disk. Once the Doppler boosting effect of the jet continuum is removed, the intrinsic FWHM values of the lines are found to be in the usual range. By contrast, the narrow permitted lines in γ-NLS1s are really narrow, since the disk and the lines are much more powerful. This also confirms that γ-NLS1 is really a new class of γ-ray emitting AGN, different from blazars and radio galaxies.

关键词： line: profiles—galaxies: jets—BL Lacertae Objects: general—galaxies: Seyfert

The pseudogenes of eukaryotic translation elongation factors (EEFs): Role in cancer and other human diseases

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Genes & Diseases 2022年第4期9卷 941-958页

作者： luigi Cristiano R&D Division Prestige18 via VecchiaTerranuova BraccioliniAR 52028Italy

The eukaryotic translation elongation factors (EEFs), i.e. EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, EEF1E1 and EEF2, are coding-genes that play a central role in the elongation step of translation but are often altered in cancer. Less investigated are their pseudogenes. Recently, it was demonstrated that pseudogenes have a key regulatory role in the cell, especially via non-coding RNAs, and that the aberrant expression of ncRNAs has an important role in cancer development and progression. The present review paper, for the first time, collects all that published about the EEFs pseudogenes to create a base for future investigations. For most of them, the studies are in their infancy, while for others the studies suggest their involvement in normal cell physiology but also in various human diseases. However, more investigations are needed to understand their functions in both normal and cancer cells and to define which can be useful biomarkers or therapeutic targets.

关键词： Cancer EEFs Non-coding RNA Pseudogene Translation Translation elongation factor

High intensity focused ultrasound,liver disease and bridging therapy

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World Journal of Gastroenterology 2013年第43期19卷 7494-7499页

作者： Mearini luigi Deparment of Urology University of PerugiaAzienda Ospedaliera di Perugia06100 PerugiaItaly

High-intensity focused ultrasound(HIFU)is a noninvasive modality that uses an extracorporeal source of focused ultrasound *** technique was introduced by Lynn et al and is able to induce coagulative necrosis in selected tissues without damaging adjacent *** HIFU has been studied for 50years,recent technological developments now allow its use for tumours of the liver,prostate and other *** liver disease,HIFU has been used to treat unresectable,advanced stages of hepatocellular carcinoma(HCC)and liver *** carcinoma is a serious health problem worldwide and is endemic in some areas because of its association with hepatitis B and C viruses(in 20%of cases).Liver transplantation(LT)has become one of the best treatments available because it removes both the tumour and the underlying liver disease such as cirrhosis(which is present in approximately 80%of cases).The prerequisite for longterm transplant success depends on tumour load and strict selection criteria regarding the size and number of tumour *** need to obtain the optimal benefit from the limited number of organs available has prompted strict selection criteria limited to only those patients with early HCC who have a better long-term outcome after *** so-called"bridging therapy"has the aim of controlling disease burden for patients who are on the organ transplant waiting *** various treatment options,transarterial chemoembolisation and radiofrequency ablation are the most popular treatment ***,Cheung et al demonstrated that HIFU ablation is a safe and effective method for the treatment of HCC patients with advanced cirrhosis as a bridging therapy and that it reduced the dropout rate from the liver transplant waiting *** this commentary,we discuss the current value of HIFU in the treatment of liver disease,including its value as a bridging therapy,and examine the potential advantages of other therapeutic strategies.

关键词： High-intensity focused ultrasound Hepatocellular carcinoma Liver transplantation Bridging therapy Waiting list

Overview of Al-based nanoenergetic ingredients for solid rocket propulsion

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Defence Technology（防务技术） 2018年第5期14卷 357-365页

作者： luigi T.DeLuca Politecnico di Milano MilanItaly Nanjing University of Science and Technology NanjingChina

The introduction of nano-sized energetic ingredients first occurred in Russia about 60 years ago and arose great expectations in the rocket propulsion community, thanks to the higher energy densities and faster energy release rates exhibited with respect to conventional ingredients. But, despite intense worldwide research programs, still today mostly laboratory level applications are reported and often for scientific purposes only. A number of practical reasons prevent the applications at industrial level: inert native coating of the energetic particles, nonuniform dispersion, aging, excessive viscosity of the slurry propellant, possible limitations in mechanical properties, more demanding safety issues, cost, and so *** paper describes the main features in terms of performance of solid rocket propellants loaded with nanometals and intends to emphasize the unique properties or operating conditions made possible by the addition of the nano-sized energetic ingredients. Steady and unsteady combustion regimes are examined.

关键词： Nanoaluminum Solid rocket propellant Burning rate Combustion Propulsion Performance

Changes in Soil Organic Carbon After Five Years of Biowaste Compost Application in a Mediterranean Vegetable Cropping System

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Pedosphere 2017年第2期27卷 328-337页

作者： Salvatore BAIANO luigi MORRA Council for Agricultural Research and Analysis of Agricultural Economics (CREA)-Researeh Center for Cereals and Industrial Crop Laboratory of Caserta Via Torrino 2 Caserta 81100 (Italy)

Biowaste compost can influence soil organic matter accumulation directly or indirectly. A 5-year experiment was conducted to assess the influence of biowaste compost on the process of soil aggregation and soil organic carbon （SOC） accumulation in a Mediterranean vegetable cropping system. The study involved four treatments： biowaste compost （COM）, mineral NPK fertilizers （MIN）, biowaste compost with half-dose N fertilizer （COMN）, and unfertilized control （CK）. The SOC stocks were increased in COM, COMN, and MIN by 20.2, 14.9, and 2.4 Mg ha-1 over CK, respectively. The SOC concentration was significantly related to mean weight diameter of aggregates （MWD）（P 〈 0.05, R^2 = 0.798 4） when CK was excluded from regression analysis. Compared to CK, COM and COMN increased the SOC amount in macroaggregates （〉 250 μm） by 2.7 and 0.6 g kg-1 soil, respectively, while MIN showed a loss of 0.4 g kg-1 soil. The SOC amount in free microaggregates （53-250 ttm） increased by 0.9, 1.6, and 1.0 g kg-1 soil for COM, COMN, and MIN, respectively, while those in the free silt plus clay aggregates （~ 53 ~m） did not vary significantly. However, when separating SOC in particle-size fractions, we found that more stable organic carbon associated with mineral fraction 〈 53 μm （MOM-C） increased significantly by 3.4, 2.2, and 0.7 g kg-1 soil for COM, COMN, and MIN, respectively, over CK, while SOC amount in fine particulate organic matter （POM） fraction （53-250 μm） increased only by 0.3 g kg-1 soil for both COM and COMN, with no difference in coarse POM 〉 250 μm. Therefore, we consider that biowaste compost could be effective in improving soil structure and long-term C sequestration as more stable MOM-C.

关键词： aggregates carbon sequestration mineral-associated organic matter particle-size fraction particulate organic matter,soil structure

Stratified gas-liquid floweAn analysis of steady state and dynamic simulation for gas-condensate systems

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Petroleum 2019年第2期5卷 128-132页

作者： luigi Raimondi Process Simulation Services Via Piave 1720027 Rescaldina Italy

In the transport of gas-liquid mixtures,where the amount of liquid condensate is low,a stratified flowpattern is predicted by mechanistic two-phase flow *** this case,the momentum balance between liquid and the gas phases is the key relation for the calculation of the steady state flow equilibrium and the existing liquid *** latter value is particularly important at low production rates for pipelines with a large number of upward and downward inclined pipe segments(making V shaped sections)where liquid can easily accumulate in the lower *** error in predicting the liquid inventory has critical consequences on the evaluation of the total pressure drop along the *** results obtained from steady state simulation can be far from reality or,at least,cannot be reproduced by a dynamic simulation of the same operating *** topics are analysed using a multiphase flow simulator developed by the author(XPSIM,eXtended Process SIMulation)which can perform compositional and fluid-mechanical analysis at the same *** state and dynamic simulations are developed for the Ormen-Lange pipeline(about 120 km long):large differences are found between the steady state and dynamic solutions.

关键词： flow dynamic state