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Seasonal variation and host sex affect bat–bat fly interaction networks in the Amazonian savannahs

Integrative Zoology 2024年第3期19卷 400-416页

作者： Paulo MEJIA Gustavo Lima URBIETA Bruna da Silva XAVIER IsaíJorge de CASTRO JoséJúlio DE TOLEDO Gustavo GRACIOLLI lucio andréviana dias William Douglas CARVALHO Programa de Pós-Graduação em Biodiversidade Tropical Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Programa de Pós-Graduação em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil Laboratório de Mamíferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Programa de Pós-Graduação em Biologia Animal Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestrial Ecology Group(TEG-UAM) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridMadridSpain

Bats are the second-most diverse group of mammals in the world,and bat flies are their main ***,significant knowledge gaps remain regarding these antagonistic interactions,especially since diverse factors such as seasonality and host sex can affect their network ***,we explore the influence of such factors by comparing species richness and composition of bat flies on host bats,as well as specialization and modularity of bat–bat fly interaction networks between seasons and adult host *** captured bats and collected their ectoparasitic flies at 10 sampling sites in the savannahs of AmapáState,northeastern region of the Brazilian *** female bats being more parasitized and recording greater bat fly species richness in the wet season,neither relationship was statistically *** pooled network could be divided into 15 compartments with 54 links,and all subnetworks comprised>12 *** total number of links ranged from 27 to 48(for the dry and wet seasons,respectively),and female and male subnetworks had 44 and 41 links,*** values were very low for the pooled network and for all *** results revealed higher bat fly species richness and abundance in the wet season,whereas specialization and modularity were higher in the dry ***,the subnetwork for female bats displayed higher specialization and modularity than the male ***,both seasonality and host sex contribute in different ways to bat–bat fly network *** studies should consider these factors when evaluating bat–bat fly interaction networks.

关键词： Amapá Amazon biome bat flies bats interaction networks

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Biliary stone causing afferent loop syndrome and pancreatitis

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World Journal of Gastroenterology 2006年第38期12卷 6229-6231页

作者： andré Roncon dias Roberto Iglesias Lopes Department of General Surgery Hospital das Clínicas Faculdade de Medicina da Universidade de So Paulo So Paulo Brazil

We report the case of an 84-year-old female who had a partial gastrectomy with Billroth-Ⅱ anastomosis 24 years ago for a benign peptic ulcer who now presented an acute pancreatitis secondary to an afferent loop syndrome. The syndrome was caused by a gallstone that migrated through a cholecystoenteric fistula. This is the first description in the literature of a biliary stone causing afferent loop syndrome.

关键词： Afferent loop syndrome Biliary stone Acute pancreatitis Gallstone ileus

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Addition of respiratory exercises to conventional rehabilitation for children and adolescents with cerebral palsy:a systematic review and meta-analysis

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World Journal of Pediatrics 2023年第4期19卷 340-355页

作者： Thálita Raysa de Lima Crispim Mansueto Gomes Neto Tafnes Rayane Lima Crispim Renivaldo Batista dias Maria Déborah Monteiro de Albuquerque Micheli Bernardone Saquetto Paulo andré Freire Magalhães Research Group of Neonatal and Pediatric Physical Therapy Baby GrUPEPetrolinaPernambucoBrazil Postgraduate Program in Rehabilitation and Functional Performance PPGRDFUniversidade de PernambucoRodovia BR 203Km 2 S/N.Vila EduardoPetrolinaPernambuco56328-900Brazil Research Group of Physiotherapy Department of Physical TherapyUniversidade Federal da BahiaSalvadorBrazil Posgraduate Program in Medicine and Health SalvadorBahiaBrazil

Background Respiratory dysfunctions are an important cause of morbidity and death in cerebral palsy(CP)*** exercises in addition to conventional rehabilitation have been suggested to improve respiratory status in CP *** objective of this systematic review and meta-analysis was to verify the effects of the addition of respiratory exercises to conventional rehabilitation on pulmonary function,functional capacity,respiratory muscle strength,gross motor function and quality of life in children and adolescents with *** We searched for randomized controlled clinical trials in PubMed/Medline,Lilacs,SciELO,EMBASE and Physi-otheraphy Evidence(PEDro)from their inception until July 2022 without language *** that included respiratory exercises(breathing exercise program;feedback respiratory training;incentive spirometer exercise;inspiratory muscle training;and combination of respiratory exercises+incentive spirometer exercise)in combination with conventional rehabilitation for children and adolescents with CP were evaluated by two independent *** mean difference(MD)and 95%confidence interval(CI)were estimated by random effect *** Ten studies met the eligibility criteria,including 324 children aged from 6 to 16 *** meta-analysis showed an improvement in inspiratory muscle strength of 22.96 cmH2O(18.63-27.27,n=55)and pulmonary function of 0.60(0.38-0.82,n=98)for forced vital capacity(L);0.22(0.06-0.39,n=98)for forced expiratory volume at 1 second(L);and 0.50(0.05-0.04,n=98)for peak expiratory flow(L/min).Functional skills in daily living activities improved in the intervention ***'assistance of daily living activities,functional capacity,gross motor function and expiratory muscle strength showed a nonsignificant *** well-being and acceptance and functioning domains improved in only one *** Emerging data show significant enhancements in inspiratory muscle stren

关键词： Breathing exercises Cerebral palsy Inspiratory muscle training Pediatrics Rehabilitation Respiratory exercise

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Modelling the role of ground-true riparian vegetation for providing regulating services in a Mediterranean watershed

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International Soil and Water Conservation Research 2023年第1期11卷 159-168页

作者： Bruno A.Aparício João Pedro Nunes Léonard Bernard-Jannin Luis Filipe dias andre Fonseca Teresa Ferreira cE3c-Centre for Ecology Evolution and Environmental Changes&CHANGE-Global Change and Sustainability InstituteFaculty of SciencesUniversity of LisbonLisbonPortugal Forest Research Centre&Laboratory TERRA School of AgricultureUniversity of LisbonLisbonPortugal Soil Physics and Land Management Group Wageningen University and ResearchWageningenNetherlands Longline Environment Ltd LondonUK

Intensive agricultural and industrial activities are often considered major sources of water ***,riparian vegetation(RV)is increasingly being promoted as a solution to balance the potentially adverse effects that agriculture may have on water ***,existing RV is often overlook in recent modelling efforts,failing to capture the current amount of ecosystem services ***,we used the Soil and Water Assessment Tool ecohydrological model to simulate the influence of ground-true RV on i)nutrient(nitrate and total phosphorus)and sediment exports from agricultural areas and ii)its effect for in-stream *** results are further compared against a set of hypothetical scenarios of different RV widths and different *** results point to a great rele-vance of existing RV in controlling in-stream concentration of sediments and nutrients where pressure from agriculture is highest,preventing them to surpass limits set in the EU Water Framework *** the other hand,in areas with industry discharges,the role of RV is limited and model results suggest that restoring RV would have limited *** illustrate how existing RV may already provide strong but not acknowledged water quality regulation services,how these services can differ substantially between nearby streams,and that effective strategies to improve water quality using RV must acknowledge existing patterns of vegetation,land use and contamination sources.

关键词： Agricultural pollution Riparian vegetation Ecosystem services Hydrological services Mediterranean region

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Satisfaction at Work and Suffering in Professional Psychic Service Mobile Service Emergency (SAMU)

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Open Journal of Epidemiology 2018年第3期8卷 93-108页

作者： Indiara Rios dos Anjos Aleska dias Vanderlei Kristiana Cerqueira Mousinho andréa Rose de Albuquerque Sarmento Omena Kelly de Brito viana Deivy Ferreira Dores Camila Maria Beder Ribeiro Girish Panjwani CESMAC University Center Maceió Brazil

Background: This study aimed to evaluate the level of professional satisfaction, to identify the presence of psychic suffering and their correlations in Emergency Medical Services professionals. Methods: The study is of the exploratory, census, descriptive, transversal type, with quantitative approach. It used three instruments: A sociodemographic questionnaire;the Professional Satisfaction Index—PSI;and the Self Report Questionnaire—SRQ-20. 200 professionals took part in the research (doctors, nurses, nursing technicians and conductors). Results: The data show that the majority of professionals are aged between 40 and 49 years old and that the largest quantity of women belong to the group of nurses. As to the PSI, the majority of professionals pointed out remuneration as the most important for satisfaction. In the overall satisfaction result, the physicians were those who had the highest level of satisfaction. Regarding the SRQ-20 scores, the group of nursing technicians and nurses had the highest prevalence for psychic suffering, with 44.56% and 43.48%. In the statistical analyses between each of the components of the professional satisfaction with the SRQ-20 scores, we verified statistically significant correlations when adopting (p Conclusions: It was concluded that the discontent of workers with remuneration and managerial issues are predominant for total dissatisfaction with work and dissatisfaction exerts a strong influence on the presence of suffering in these professionals.

关键词： Satisfaction in the Job Psychic Suffering Medical Service of Emergency

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Glycoproteogenomics: Setting the Course for Next-generation Cancer Neoantigen Discovery for Cancer Vaccines

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Genomics, Proteomics & Bioinformatics 2021年第1期19卷 25-43页

作者： José Alexandre Ferreira Marta Relvas-Santos andreia Peixoto andréM.N.Silva Lúcio Lara Santos Experimental Pathology and Therapeutics Group Portuguese Institute of OncologyPorto 4200-072Portugal Institute of Biomedical Sciences Abel Salazar University of PortoPorto 4050-313Portugal Porto Comprehensive Cancer Center(P.ccc) Porto 4200-072Portugal REQUIMTE-LAQV Department of Chemistry and BiochemistryFaculty of Sciences of the University of PortoPorto 4169-007Portugal

Molecular-assisted precision oncology gained tremendous ground with high-throughput next-generation sequencing(NGS),supported by robust *** quest for genomicsbased cancer medicine set the foundations for improved patient stratification,while unveiling a wide array of neoantigens for *** pre-clinical and clinical studies have successfully used tumor-specific peptides in vaccines with minimal off-target ***,the low mutational burden presented by many lesions challenges the generalization of these solutions,requiring the diversification of neoantigen *** utilizing customized databases for protein annotation by mass spectrometry(MS)is a powerful tool toward this *** the concept toward exploring proteoforms originated from post-translational modifications(PTMs)will be decisive to improve molecular subtyping and provide potentially targetable functional nodes with increased cancer *** through the path of systems biology,we highlight that alterations in protein glycosylation at the cell surface not only have functional impact on cancer progression and dissemination but also originate unique molecular fingerprints for targeted ***,we discuss the outstanding challenges required to accommodate glycoproteomics in oncoproteogenomics *** envisage that such rationale may flag a rather neglected research field,generating novel paradigms for precision oncology and immunotherapy.

关键词： Glycoproteogenomics Oncoproteogenomics Cancer neoantigens Glycosylation Precision oncology

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Application of Neural Networks in Probabilistic Forecasting of Earthquakes in the Southern California Region

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International Journal of Geosciences 2018年第6期9卷 397-413页

作者： Vitor H. A. dias andrés R. R. Papa Geophysics Department Observatório Nacional Rio de Janeiro Brazil Physics Institute Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil

During the last few decades, many statistical physicists have devoted re-search efforts to the study of the problem of earthquakes. The purpose of this work is to apply methods of Statistical Physics and network systems based on “neurons” in the study of seismological events. Data from the Advanced National Seismic System (ANSS) of Southern California were used to verify the relationship between time differences between consecutive seismic events with magnitudes greater than 3.0, 3.5, 4.0 and 4.5 through the modeling of neural networks. The problem we are analyzing is time differences between seismological events and how these data can be adopted as a time series with non linear characteristic. We are therefore using the multilayer perceptron neural network system with a backpropagation learning algorithm, because its characteristics allow for the analysis of non-linear data in order to obtain statistical results regarding the probabilistic forecast of tremor occurrence.

关键词： Neurons Multi-Layer Perceptron Backpropagation Prediction

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Super modules-based active QR codes for smart trackability and IoT:a responsive-banknotes case study

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npj Flexible Electronics 2020年第1期4卷 93-101页

作者： João F.C.B.Ramalho Sandra F.H.Correia Lianshe Fu Lília M.S.dias Pedro Adão Paulo Mateus Rute A.S.Ferreira Paulo S.andré Department of Physics and CICECO-Aveiro Institute of Materials University of Aveiro3810-193 AveiroPortugal Department of Computer Science and Engineering and Instituto de Telecomunicações Instituto Superior TécnicoUniversidade de Lisboa1049-001 LisbonPortugal Department of Mathematics and Instituto de Telecomunicações Instituto Superior TécnicoUniversidade de Lisboa1049-001 LisbonPortugal Department of Electrical and Computer Engineering and Instituto de Telecomunicações Instituto Superior TécnicoUniversidade de Lisboa1049-001 LisbonPortugal

The general use of smartphones assigns additional relevance to QR codes as a privileged tool to the Internet of Things(IoT).Crucial for QR codes is the evolution to IoT-connected smart tags with enhanced storage capacity and secure *** the concept of super-modules(s-modules)built from adjacent spatial multiplexed modules with regular geometrical shapes,assisted by colour multiplexing,we modelled and design a single QR code with,at least,the triple storage capacity of an analogous size black/white QR code,acting as a smart-tag ensuring restrict access and *** s-modules are printed using luminescent low-cost and eco-friendly inks based on organic-inorganic hybrids modified by lanthanides with multiplexed colour emission in the orthogonal RGB *** access to the restrict information is attained only under UV irradiation and encrypted for secure *** concept of active QR codes for smart trackability and IoT was materialised through the development of a free friendly-user mobile app.

关键词： IoT smart modules

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Prognostic implications of tumor-infiltrating lymphocytes in association with programmed cell death ligand 1 expression in remnant gastric cancer

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Chinese Journal of Cancer Research 2022年第6期34卷 612-622页

作者： Marina Alessandra Pereira Marcus Fernando Kodama Pertille Ramos andré Roncon dias Leonardo Cardili Rafael Dyer Rodrigues de Moraes Renan Ribeiro E Ribeiro Venancio Avancini Ferreira Alves Bruno Zilberstein Evandro Sobroza de Mello Ulysses Ribeiro Jr Department of Gastroenterology Instituto do Cancer do Estado de Sao PauloHospital das ClinicasFaculdade de MedicinaUniversidade de Sao Paulo(ICESP-HCFMUSP)Sao PauloSP 01246-000Brazil Department of Pathology Instituto do Cancer do Estado de Sao PauloHospital das ClinicasFaculdade de MedicinaUniversidade de Sao Paulo(ICESP-HCFMUSP)Sao PauloSP 01246-000Brazil

Objective:Remnant gastric cancer(RGC)is usually associated with a worse *** they are less common and very heterogeneous tumors,new prognostic and reliable determinants are required to predict patients’clinical course for *** study aimed to investigate the tumor-infiltrating lymphocytes(TILs)and programmed cell death ligand 1(PD-L1)status as prognostic biomarkers in a cohort of patients with RGC to develop an immunerelated ***:Patients with gastric cancer(GC)who underwent curative intent gastrectomy were retrospectively *** resections with histological diagnosis of gastric adenocarcinoma were enrolled in the *** risk score based on immune parameters was developed using binary logistic regression *** were divided into high-risk(HR),intermediate-risk(IR),and low-risk(LR)groups based on their immune *** markers(CD3+,CD4+/CD8+T cells and PD-L1)were selected for their potential prognostic,therapeutic value,and evaluated by immunohistochemistry(IHC).Results:A total of 42 patients with RGC were enrolled in the *** score based on immune parameters exhibited an accuracy of 79%[the area under the receiver operating characteristic curve(AUC)=0.79,95%confidence interval(95%CI),0.63-0.94,P=0.002],and the population was divided into 3 prognostic groups:10(23.8%)patients were classified as LR,15(35.7%)as IR,and 17(40.5%)as HR *** were no differences in clinicopathological and surgical characteristics between the three *** survival analysis,HR and IR groups had worse disease-free survival and overall survival rates compared to the LR *** the multivariate analysis,lymph node metastasis and the immune score risk groups were independent factors related to worse ***:A scoring system with immune-related markers was able to distinguish prognostic groups of RGC associated with ***,tumor-infiltrating immune lymphocytes and PD-L1 status may serve as a potential prognostic bi

关键词： Stomach neoplasms gastric remnant tumor-infiltrating lymphocytes immune microenvironment

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The Porcine Pulmonary Surfactant Protein A (pSP-A) Immunogenicity Evaluation in the Murine Model

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Pharmacology & Pharmacy 2010年第1期1卷 27-32页

作者： Sandra de Cássia dias Fernanda lucio dos Santos Dirce Sakauchi Dmitri Iourtov Isaias Raw Flavia Saldanha Kubrusly Engenharia de Bioprocessos-Campus Alto do Paraopeba Universidade Federal de São João Del-Rei Divisão Bioindustrial Instituto Butantan Centro de Biotecnologia Instituto Butantan

This paper investigated the porcine surfactant protein A (pSP-A) immunogenicity in murine model. Many elegant stu-dies about SP-A therapeutic applications are available however specific studies about its exogenous immunogenicity were not easily assumed. Therefore, we investigated the immunogenicity of this porcine protein in mice. The mice re-ceived pSP-A subcutaneously on days 0 and 7. The animals were observed during 90 days and the blood was collected on days 30, 60 and 90 for assessment the immunogenic potential of pSP-A. Some animals showed circulating antibodies above the screening cut point, which was calculated based on control mice sera signals. However, those antibodies were considered false positive read-outs by the performed competitive inhibition assay. Also no neutralizing antibodies were detected able to avoid the porcine protein ability to promote lipid aggregation. So far in this model, porcine surfactant protein-A could be considered not immunogenic.

关键词： Immunogenicity Porcine Surfactant Protein A Anti-Drug Antibody Murine Model

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