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Intrumer:A Multi Module Distributed explainable IDS/IPS for Securing Cloud environment

Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen banu A S.K.b.Sangeetha Department of Computer Science and engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network *** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tackle these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattacks and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTRUMeR,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemodulesworking together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network traffic are taken into account to classify them as normal or malicious *** classified results are further analyzed by the explainable Prevention Module(XPM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark IDS datasets CICIDS 2017,Honeypots,and NSL-KDD were conducted to demonstrate the efficiency of the INTRUMeR model in detecting network trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining better performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTRUMeR in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

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Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

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Federated Learning’s Role in Next-Gen TV Ad Optimization

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Computers, Materials & Continua 2025年第1期82卷 675-712页

作者： Gabriela Dobrita Simona-Vasilica Oprea Adela bâra Department of economic Informatics and Cybernetics Bucharest University of Economic StudiesBucharest010374Romania

In the rapidly evolving landscape of television advertising,optimizing ad schedules to maximize viewer engagement and revenue has become *** methods often operate in silos,limiting the potential insights gained from broader data analysis due to concerns over privacy and data *** article introduces a novel approach that leverages Federated Learning(FL)to enhance TV ad schedule optimization,combining the strengths of local optimization techniques with the power of global Machine Learning(ML)models to uncover actionable insights without compromising data *** combines linear programming for initial ads scheduling optimization with ML—specifically,a K-Nearest Neighbors(KNN)model—for predicting ad spot *** into account the diversity and the difficulty of the ad-scheduling problem,we propose a prescriptivepredictive approach in which first the position of the ads is optimized(using Google’s OR-Tools CP-SAT)and then the scheduled position of all ads will be the result of the optimization ***,this output becomes the target of a predictive task that predicts the position of new entries based on their characteristics ensuring the implementation of the scheduling at large scale(using KNN,Light Gradient boosting Machine and Random Forest).Furthermore,we explore the integration of FL to enhance predictive accuracy and strategic insight across different broadcasting networks while preserving data *** FL approach resulted in 8750 ads being precisely matched to their optimal category placements,showcasing an alignment with the intended diversity ***,there was a minimal deviation observed,with 1133 ads positioned within a one-category variance from their ideal placement in the original dataset.

关键词： Ad scheduling prescriptive-predictive approach federated learning KNN

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Geographical location affects size and materials used in the construction of european Pied Flycatcher(Ficedula hypoleuca) nests

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Avian Research 2019年第2期10卷 111-125页

作者： Kevin b.briggs lucia e.b.ddle D.Charles Deeming Joseph banks Laboratories School of Life SciencesUniversity of Lincoln

background: Nest construction is a key element of avian reproductive behaviour and the result is often a complex structure that is used for incubation of eggs, which represents an extended phenotype. It is known that nest construction is a plastic behaviour but the extent to which plasticity is observed in a single species with a wide geographical distribution is largely unknown. This study sought to better understand variation in nest size and composition across a very wide geographical area. The hypothesis suggested that location would affect size but not composition of nests of the european Pied Flycatcher (Ficedula hypoleuca). Methods: Nests and reproductive data were collected from seventeen study sites, spread over 6° of latitude and 3.3° of longitude on the island of Great britain. Dimensions of nests were measured before they were deconstructed to determine the masses and types materials used in the outer nest and the cup lining. Results: Geographical variation was observed in base thickness of nests but not many other dimensions. Nests varied in composition but were mainly made of leaf, moss, bark, grass, root and fern. Moss was used more to the north and east of the study area compared with more leaf mass towards the south and west. The species of leaf and bark used in the nests varied between geographical locations. Additionally, the use of leaves or bark from a particular tree species did not reflect the incidence of the tree species in the immediate territory. Conclusions: This study showed that nest composition was affected by geographical location over a wide area. Variation between nests at each location was high and so it was concluded that differences in nest composition reflect individual selection of materials but evidence is such that it remains unclear whether this is deliberate to fulfil a specific role in the nest, or simply opportunistic with birds simply picking up materials with the appropriate characteristics as they find them outside the

关键词： breeding success Ficedula hypoleuca Latitude Longitude Nest composition Nest size Nest structure

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Free Convention Heat Transfer from an Isothermal Horizontal Thin Strip:the Influence of the Prandtl Number

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Journal of Thermal Science 2014年第6期23卷 586-592页

作者： lucia Fontana Dipartimento di Architettura Universita degli Studi Roma Trevia Madonna dei Monti40 00184 RomaItaly.

Simultaneous free convection above and below a uniformly heated horizontal plate has been widely investigated,both in the case of an isothermal surface,and of a uniformly heated surface,but always assuming only air as fluid(Pr=0.7).Nevertheless,there are works dealing with horizontal plates whose results show that the Nu dependence on Pr may not be simply expressed by a power law with the same exponent of the Gr *** it was considered useful to study the Prandtl number influence in the case of the isothermal horizontal *** show that,while for the lower surface of the strip the Nu dependence in Gr can be expressed by a power law with an exponent close to the Gr one,for the upper surface the exponent is sensibly *** equations related to the investigated situations are proposed.

关键词： Isothermal horizontal strip free convection Prandtl number influence

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effect of template shape on metal nanoimprinting:a dislocation dynamics study

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Journal of Zhejiang University-Science A(Applied Physics & engineering) 2010年第10期11卷 722-726页

作者： lucia NICOLA Department of Materials Science and engineering Delft University of Technology

Dislocation dynamics simulations are performed to investigate the effect of template shape on the nanoimprinting of metal layers. To this end, metal thin films are imprinted by a rigid template made of an array of equispaced indenters of various shapes, i.e., rectangular, wedge, and circular. The geometry of the indenters is chosen such that the contact area is approximately the same at the final imprinting depth. Results show that, for all template shapes, the final patterns strongly depend on the dislocation activity, and that each imprint differs from the neighboring ones. Large material pile ups appear between the imprints, such that polishing of the metal layer is suggested for application of the patterns in electronics. Rectangular indenters require the lowest imprinting force and achieve the deepest retained imprints.

关键词： Nanoimprinting Dislocation dynamics Simulations

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PHYSICAL MODeL FOR THe eNGINeeRING ANALYSISOF THe THeRMOeLASTICLTY OF SOLID bODIeS

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Chinese Journal of Mechanical engineering 2000年第3期13卷 165-170,177页

作者： lucia Umberto I.N.F.M.-Istituto Nazionale per la Fisica della Materia Nucl 意大利 Rivalta Sc I-15047

The thermal behaviour of the solids under elastic deformations is analysed in order to obtain a model which combines the molecular dynamics results with the global thermal behaviour of the solids under elastic transformations. The result obtained consists of the introduction of the thermal behaviour in the Parrinello-Rahman model, obtaining the thermal molecular dynamic model useful in the analysis of the thermoelastic behaviour of solids.

关键词： PHYSICAL MODeL FOR THe eNGINeeRING ANALYSISOF THe THeRMOeLASTICLTY OF SOLID bODIeS

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NeCAb family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAb1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAb1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAb2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAb3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAb proteins exhibit distinct subcellular localizations: NeCAb1 is found in the nucleus and cytosol, NeCAb2 resides in endosomes and the plasma membrane, and NeCAb3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAb proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAb proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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Smart superabsorbent alginate/carboxymethyl chitosan composite hydrogel beads as efficient biosorbents for methylene blue dye removal

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Journal of Materials Science & Technology 2023年第28期159卷 81-90页

作者： Zhen Zhang Noureddine Abidi lucian lucia Department of Forest biomaterials NC State UniversityRaleighNCUSA Fiber and biopolymer Research Institute Department of Plant and Soil ScienceTexas Tech UniversityLubbockTXUSA Department of Chemistry NC State UniversityRaleighNCUSA

The presence of toxic dyes in the aqueous medium has threatened environmental safety, and thereby re- moving them from wastewater in an efficient way is highly desired. Herein, the efficient biosorbents were successfully fabricated via a facile physical gelation process of sodium alginate (SA) and carboxymethyl chitosan (CMCTS) in an acidic aqueous solution. The as-prepared hydrogel beads not only displayed water superabsorbent properties and pH-responsive swelling characters but also exhibited excellent methylene blue (Mb) adsorption capacity removal efficiency with experimental maximum Mb adsorption capacity of 2518 and 1005 mg g -1 , which are comparable with most reported lignocellulosic and alginate-based hydrogels. The Mb adsorption process fitted well in different kinetic and isotherm models and became more heterogeneous in concentrated Mb solutions as verified by principal component analysis results. The adsorption mechanism was proposed, and the high dye absorbency was attributed to the strong electro- static forces between adsorbents and adsorbates. Our current study provides a promising and sustainable composite hydrogels platform targeted to dye decontamination.

关键词： Hydrogel Dye adsorption Composites Superabsorbent Sodium alginate Carboxymethyl chitosan

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Minimal Free Resolutions of Zero-dimensional Schemes in P1 ×P1

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Algebra Colloquium 2015年第1期22卷 97-108页

作者： Paola bonacini lucia Marino Universita degli Studi di Catania ViMe A. Doria 6 95125 Catania Italy

Let X be a zero-dimensional scheme in p1 × p1. Then X has a minimal free resolution of length 2 if and only if X is ACM. In this paper we determine a class of reduced schemes whose resolutions, similarly to the ACM case, can be obtained by their Hilbert functions and depend only on their distributions of points in a grid of lines. Moreover, a minimal set of generators of the ideal of these schemes is given by curves split into the union of lines.

关键词： resolution Hilbert function separators

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