检索结果-南通市图书馆

Pediatric nonalcoholic fatty liver disease,metabolic syndrome and cardiovascular risk

World Journal of Gastroenterology 2011年第26期17卷 3082-3091页

作者： lucia Pacifico Valerio Nobili Caterina Anania Paola Verdecchia Claudio Chiesa Department of Pediatrics Sapienza University of Rome Department of Hepato-gastroenterology and Nutrition Pediatric Hospital "Bambino Gesù" Institute of Translational Pharmacology National Research Council

Nonalcoholic fatty liver disease(NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol *** mildest form is simple steatosis in which triglycerides accumulate within hepatocytes.A more advanced form of NAFLD,nonalcoholic steatohepatitis,includes inflammation and liver cell injury,progressive to cryptogenic *** has become the most common cause of chronic liver disease in children and *** recent rise in the prevalence rates of overweight and obesity likely explains the NAFLD epidemic *** is strongly associated with abdominal obesity,type 2 diabetes,and dyslipidemia,and most patients have evidence of insulin ***,NAFLD shares many features of the metabolic syndrome(MetS),a highly atherogenic condition,and this has stimulated interest in the possible role of NAFLD in the development of *** evidence suggests thatNAFLD is associated with a significantly greater overall mortality than in the general population,as well as with increased prevalence of cardiovascular disease(CVD),independently of classical atherosclerotic risk ***,several studies including the pediatric population have reported independent associations between NAFLD and impaired flow-mediated vasodilatation and increased carotid artery intimal medial thickness-two reliable markers of subclinical atherosclerosis-after adjusting for cardiovascular risk factors and ***,the rising prevalence of obesity-related MetS and NAFLD in childhood may lead to a parallel increase in adverse cardiovascular *** children,the cardiovascular system remains plastic and damage-reversible if early and appropriate interventions are established *** goals for NAFLD should address nutrition,physical activity,and avoidance of smoking to prevent not only end-stage liver disease but also CVD.

关键词： Nonalcoholic fatty liver disease Metabolicsyndrome Cardiovascular risk Children

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Finding a way to preserve mitochondria: new pathogenic pathways in experimental multiple sclerosis

引用

Neural Regeneration Research 2019年第1期14卷 77-78页

作者： Andrea Mancini Lorenzo Gaetani lucia Gentili Massimiliano Di Filippo Clinica Neurologica Dipartimento di Medicina Università degli Studi di Perugia

Multiple sclerosis(MS)is a chronic disorder affecting central nervous system(CNS)in which inflammatory and neuro-degenerative features coexist since the earlier phases of the disease(Reich et al.,2018).During last years,attention has been directed toward the possible pathogenic pathways linking these two different features characterizing MS,in order to acquire a better understanding of the disease pathogenesis and to design new disease modifying *** available therapies for MS are primarily

关键词：小径病原硬化多重试验性线粒体保存疾病

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Description of a Propulsion Unit Used in Guiding a Walking Machine by Recognizing a Three-point Bordered Path

引用

Chinese Journal of Mechanical Engineering 2016年第6期29卷 1157-1166页

作者： NUNEZ-ALTAMIRANO Diego A JUAREZ-CAMPOS Ignacio MARQUEZ-PEREZ lucia FLORES-DIAZ Ociel School of Mechanical Engineering Universidad Michoacana de San Nicolas de Hidalgo Morelia Michoacan Mexico

A reconfigurable propulsion unit based on the Peaucellier-Lipkin mechanism has the ability to describe exact straight or curved paths depending on the selected ratio between the lengths of two of its links. The Peaucellier-Lipkin mechanism with one degree of freedom is transformed into a more sophisticated parallel kinematic chain by including four more degrees of freedom. The resulting propulsion unit is able to adapt its kinematic structure and reach instant centers of rotation, in accordance with the presence of three points that border a geometric path. A laser sensor mounted on the body of the machine detects each point. Once the machine has detected the exact location of the border of the road, it walks along a curve parallel to that border. Although the proposed research describes only one propulsion unit or leg, the methodology can be applied to all the legs of the walking machine. The novel 5-DOF leg is able to reach different centers of rotation, providing either the concave or convex arcs that satisfy the basic principle of displacement of walking machines.

关键词： Propulsion unit Peaucellier-Lipkin walking machine straight line mechanism.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Research to Understand the Past Present and Future Dynamics of M&A in the Luxury Sector, If They Pay and Which Effects Generate on Consumers

A Research to Understand the Past Present and Future Dynamic...

引用

作者： lucia Pierini 复旦大学

学位级别：硕士

The main goal of this thesis is to investigate on the value implications of mergers and acquisitions (M&A) conducted worldwide in the luxury sector over the period from nineties to June2012. The first step has been try to understand the luxury goods industry, its key players and their performances, in order to have a clearer idea. After having explained what is the process generally run for M&A' activities and explore what is happened in the recent years, we try to answer to a critical question:does M&A in the luxury sector pay? Mainly through the use of event studies' methodology has been discovered that market adjustment reveals positive results announcement effects and consequently can be interpreted as value creating. The analysis attempts to understand also which will be the future trends of M&A activity in terms of bidders, targets and geographical location, and a certainty arises:future M&A will be accomplished. Last but not least a research of the effects produced by M&A in the industry on consumers welfare has been done:prices increase but consumers seem not to care too much about that.

关键词： luxury goods sector equity companies return prices extremely stores instead

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Digital Library Service Initiative of the Hong Kong Institute of Education Library

引用

上海交通大学学报 2003年第S1期37卷 95-100页

作者： lucia Tsui Sidney Cheng Ivan Chan HKIEd Library HKIEd Library HKIEd Library

This paper presented the philosophy and the design concepts of the Hong Kong Institute of Education (HKIEd) Library Digital Library Service Initiative, focusing on two in house developed digital library components, EdIS and EdVideo, around its core digital library components of the INNOPAC Integrated Library System, Library Website, electronic resources from vendors. Description on the development of these systems was made.

关键词： EdIs EdVideo Innopac digital library projects

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Consequences of Helicobacter pylori infection in children

引用

World Journal of Gastroenterology 2010年第41期16卷 5181-5194页

作者： lucia Pacifico Caterina Anania John F Osborn Flavia Ferraro Claudio Chiesa Department of Pediatrics Sapienza University of Rome 324 I-00161 Rome Italy Department of Public Health Sciences Sapienza University of Rome I-00185 Rome Italy Department of Molecular Medicine National Research Council I-00133 Rome Italy

Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the hu-man stomach for many decades without adverse con-sequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae.

关键词： Helicobacter pylori Children Gastrointestinal diseases Epigastric pain Anemia Growth retardation Chronic idiopathic thrombocytopenic pupura

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The phantom and the supernumerary phantom limb:historical review and new case

引用

Neuroscience Bulletin 2011年第6期27卷 359-365页

作者： Gabriele Cipriani lucia Picchi Marcella Vedovello Angelo Nuti Mario Di Fiorino Versilia医院神经科 Via Aurelia55043Lido di Camaiore(Lu)意大利 Versilia医院精神科 Via Aurelia55043Lido di Camaiore(Lu)意大利

The way we experience the world is determined by the way our brain *** phantom limb phenomenon,which is a delusional belief of the presence of a non-existent limb,has a particular fascination in *** positive phenomenon of the phantom limb raises theoretical questions about its *** a stroke,some patients experience the perception of an extra limb in addition to the regular set of two arms and two *** complex cognitive and perceptual distortion is called supernumerary phantom ***,we review the pathogenesis and historical aspects,and report a new case.

关键词： phantom limb supernumerary phantom limb body schema

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Serum tumor markers not useful in screening patients with pancreatic mucinous cystic lesions associated with malignant changes

引用

Hepatobiliary & Pancreatic Diseases International 2016年第5期15卷 553-557页

作者： Raffaele Pezzilli lucia Calculli Gianvico Melzi d'Eril Alessandra Barassi Department of Digestive System Sant’Orsola-Malpighi Hospital Department of Radiology Sant’Orsola-Malpighi Hospital Department of Health Sciences SanPaolo HospitalUniversity of Milan

BACKGROUND: Serum cancer antigen 19-9 (CA19-9) pro-vides additional information about mucinous cystic pancre-atic neoplasm (MPN). This study was undertaken to assess both CA19-9 and carcinoembryonic antigen (CEA) serum concentrations in consecutive patients affected by MPNs and other chronic benign and malignant pancreatic diseases. We also evaluated whether serum CA19-9 and CEA determina-tions provide additional information such as the presence of invasive carcinoma in MPN patients. METHODS: Serum CA19-9 and CEA from 91 patients with pancreatic diseases were tested by commercially available kits at the time of diagnosis. The upper reference limit of serum CA19-9 was 37 U/mL and that of serum CEA was 3 ng/mL. RESULTS: Thirty-ifve patients was diagnosed with chronic pancreatitis (CP), 32 with MPN, and 24 with pancreatic ductal adenocarcinoma (PDAC) conifrmed histologically. Surgery was carried out in 5 CP patients, in 10 MPN patients (7 of them had severe dysplasia), and 9 PDAC patients. Serum CA19-9 activity was high in 12 (34.3%) CP patients, in 7 (21.9%) MPN patients, and in 12 (50.0%) PDAC patients (P=0.089). High se-rum CEA concentrations were noted in 6 (17.1%) CP patients, in 6 (18.8%) MPN patients, and in 12 (50.0%) PDAC patients (P=0.010). In the 7 MPN patients associated with histological-ly conifrmed severe dysplasia, 3 (42.9%) patients had elevated serum activity of serum CA19-9, and 2 (28.6%) patients had high levels of CEA. CONCLUSION: Serum determination of oncological markers is not useful in selecting MPN patients with malignant changes.

关键词： cancer antigen 19-9 carcinoembryonic antigen cystic pancreatic neoplasms chronic pancreatitis pancreatic ductal adenocarcinoma laboratory assessment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Early detection of tomato bacterial canker by reflectance indices

引用

Information Processing in Agriculture 2022年第2期9卷 184-194页

作者： Gabriela Cordon Carolina Andrade lucia Barbara Ana Maria Romero Universidad de Buenos Aires Consejo Nacional de Investigaciones Cientı´ficas y Te´cnicasInstituto de Investigaciones Fisiolo´gicas y Ecolo´gicas Vinculadas a la Agricultura(IFEVA)Facultad de Agronomı´aBuenos AiresArgentina Universidad de Buenos Aires Facultad de Agronomı´aA´rea de Educacio´n AgropecuariaBuenos AiresArgentina Universidad de Buenos Aires Facultad de Agronomı´aCa´tedra de Fitopatologı´aBuenos AiresArgentina

Early detection of infected asymptomatic plants could prevent the dissemination of tomatobacterial canker throughout the crop and, thus, reduce associated economic losses. Reflectance spectroscopy has been proposed for the detection of diseases in plants, mainlycaused by foliar fungal pathogens. In contrast, bacterial canker is a vascular disease thatdoes not produce visible foliar symptoms until it is too late to avoid contagion to otherplants. The effects of the disease on the conductivity of the xylem have an impact onthe water content of the leaves;initially, a subtle effect that cannot be assessed with thenaked eye but can be evaluated by reflectance spectroscopy. The objective of this workwas to identify indices, based on the reflectance spectral signature of the plants, for thedetection of tomato plants affected by bacterial canker prior to the appearance of symptoms. To verify that the proposed methodology is applicable to a broad range of tomatogenotypes, two experiments were carried out with different tomato cultivars grown in potsand another on the ground in a greenhouse. Plants were inoculated with the pathogenicbacteria and the reflectance spectrum of the apical leaflet of two leaves per plant wereobtained before symptoms expression;several spectral indices were calculated from thereflectance spectra. Three indices, of the shortwave-infrared zone, allowed the detectionof bacterial canker inoculated plants in a fast and non-destructive way, up to one weekbefore symptoms were visible: Normalized Difference Water Index (NDWI), Simple Ratioof Water Index (SRWI) and Water Index 1 180 (WI1180). Our research demonstrates, forthe first time, the usefulness of spectral indices sensitive to water content for the identifi-cation of diseased plants. These indices arise as a promising tool for the early detection ofvascular plant diseases, that could be integrated into sustainable management plans.

关键词： Clavibacter michiganensis subsp. michiganensis Bacterial wilt Reflectance indices Solanum lycopersicum L

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Studies on Youth Radio Listening Habits in the Convergence Era in Lesotho

Studies on Youth Radio Listening Habits in the Convergence E...

引用

作者： Hlompho lucia Letsie 中国传媒大学

学位级别：硕士

当前,融合时代广播收听习惯和内容偏好的巨大变化凸显了研究莱索托青年听众广播收听习惯和广播规制的实践和理论问题的必要性与紧迫性。为此,本文探讨媒介融合时代莱索托青年的收听习惯的变化,尤其是发掘现在与以前的广播收听习惯有何... 详细信息

当前,融合时代广播收听习惯和内容偏好的巨大变化凸显了研究莱索托青年听众广播收听习惯和广播规制的实践和理论问题的必要性与紧迫性。为此,本文探讨媒介融合时代莱索托青年的收听习惯的变化,尤其是发掘现在与以前的广播收听习惯有何不同。基于媒介融合进程的不断推进,本研究基于使用和满足理论以及媒体依赖理论并采用运用封闭式与开放式调查问卷法以及开放式深度访谈等混合研究法,分析当代青年互联网广播、数字广播、地面无线广播收听和双重收听行为,探讨青年的收听偏好变化、行为意图、使用满足以及媒介依赖性问题,进而对莱索托广播规制提出一些建议。研究发现,首先,莱索托青年广播收听习惯发生了变化,其中67%的受访者早上用手机收听广播(中午则为45%)。而且58%的受访者通过手机APP收听,一半受访者偏好在汽车收音机上收听。其次,莱索托的广播电台亟需向数字广播转型,以便散居国外的巴索托人能够收听本国信息并与世界沟通。第三,亟待对当代广播听众行为习惯变化进行研究,以改革规制和新兴广播服务政策,使其与听众生活方式的改变相吻合。而且,媒介融合的规制和指导方针须进行彻底改革,以应对广播的变化,因为一些广播电台使用免费的在线网站进行音频流。最后,本文建议对莱索托的广播收听习惯转变予以进一步研究,以推动政策改革战略向前发展,从而使广播规制适应莱索托听众变化和广播行业转型。

关键词：收听习惯融合莱索托青年

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：