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Mortality Trends for Neglected Tropical Diseases in the State of Sergipe,Brazil,1980-2013

Infectious Diseases of Poverty 2017年第1期6卷 173-180页

作者： Marcos Antonio Costa de Albuquerque Danielle Menezes Dias lucas teixeira vieira Carlos Anselmo Lima Angela Maria da Silva University Hospital Federal University of SergipeRua Claudio Batista s/nB.Santo AntonioAracajuSE 49060-108Brazil Post-doc Medicine Unit Federal University of SergipeRua Claudio Batista s/nB.Santo AntonioAracajuSE 49060-108Brazil

Background:Neglected Tropical Diseases are a set of communicable diseases that affect the population so low socioeconomic status,particularly 1.4 billion people who are living below the poverty *** study has investigated the magnitude and mortality time trends for these diseases in the state of Sergipe,Northeast Region of ***:We conducted an ecological study of time series,based on secondary data derived from the Mortality Information System of the Ministry of *** mortality rates(crude,age-standardized rates and proportional ratio)were calculated from the deaths due to Neglected Tropical Diseases in the state of Sergipe,from 1980 to *** time trends were obtained using the Joinpoint regression ***:Three hundred six thousand and eight hundred seventy-two deaths were certified in the state and Neglected Tropical Diseases were mentioned as the underlying cause in 1,203 certificates(0.39%).Mean number of deaths was 35.38 per year,and crude and age-standardized mortality rates were,respectively:2.16 per 100000 inhabitants(95%CI:1.45-2.87)and 2.87 per 100000 inhabitants(95%CI:1.93-3.82);the proportional mortality ratio was 0.41%(95%CI:0.27-0.54).In that period,Schistosomiasis caused 654 deaths(54.36%),followed by Chagas disease,with 211(17.54%),and by Leishmaniases,with 142(11.80%)*** other diseases totalized 196 deaths(16.30%).There were increasing mortality trends for Neglected Tropical Diseases,Schistosomiasis and Chagas disease in the last 15 years,according to the age-standardized rates,and stability of the mortality trends for ***:The Neglected Tropical Diseases show increasing trends and are a real public health problem in the state of Sergipe,since they are responsible for significant mortality *** following diseases call attention for showing greater number of deaths in the period of study:Schistosomiasis,Chagas disease and *** finally suggest that public managers take appropri

关键词： Mortality Neglected tropical diseases Trends Joinpoint

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King's College criteria and the Clichy-Villejuif criteria require adjustments for assessing acute liver failure due to yellow fever

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World Journal of Transplantation 2025年第1期15卷 124-134页

作者： Bruno da Silva Athanasio Antonio Marcio de Faria Andrade Vivian Vasconcelos Costa Juliano Felix Castro Silverio Leonardo Macedo Garcia Mauro Martins teixeira Daniele da Gloria Souza Paula vieira teixeira Vidigal Cristiano Xavier Lima Department of Surgery Federal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Liver Transplantation Unit Felicio Rocho HospitalBelo Horizonte 30110-934Minas GeraisBrazil Department of Morphology Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil Department of Biochemistry and Immunology Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil Department of Pathology Federal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil

BACKGROUND Acute liver failure(ALF)is a severe condition characterized by rapid deterioration of liver function in individuals without preexisting liver *** transplantation(LT)is the most impactful *** fever(YF)is an infectious disease that primarily affects the liver and has a high mortality ***,LT can be a viable option for treating rare cases with extensive liver ***,the criteria for assessing the severity of ALF and determining the indications for transplantation have not been specifically validated for cases caused by *** To present necessary adjustments to established scoring systems for ALF secondary to *** This was an observational,retrospective,single-center *** consecutive patients with confirmed ALF due to YF were monitored in the intensive care unit by a specialized liver transplant team during a three-month epidemic outbreak in *** hospitalization,general supportive therapeutic measures were implemented,and the patients were regularly assessed using the King's College criteria and the Clichy-Villejuif criteria to determine the severity of liver *** is considered a viable measure for patients with signs of end-stage liver *** Eight of 14(57%)patients developed severe neurological alterations within the first 96 hours after hospital *** patients underwent emergency LT,and despite a moderate viral infection of the graft after transplantation,the 5-year survival rate was 50%.Although the King's College criteria and the Clichy-Villejuif criteria are the main scoring systems for ALF,they are insufficient for predicting the risk of mortality in this context,primarily because of low serum bilirubin levels in the final stage of the disease and significant disparities between coagulation abnormalities and patient *** To ensure good applicability in cases of YF-induced ALF,the authors suggest adaptations to the King's College and Clichy-Vill

关键词： Yellow fever Acute liver failure Liver transplantation King's College criteria Clichy-Villejuif criteria

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Characterization of soil fauna under the influence of mercury atmospheric deposition in Atlantic Forest, Rio de Janeiro, Brazil

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Journal of Environmental Sciences 2015年第6期27卷 217-227页

作者： Andressa Cristhy Buch Maria Elizabeth Fernandes Correia Daniel Cabral teixeira Emmanoel vieira Silva-Filho Departamento de Geoquímica Universidade Federal Fluminense Embrapa Agrobiologia BR 465 km 7

The increasing levels of mercury（Hg） found in the atmosphere arising from anthropogenic sources, have been the object of great concern in the past two decades in industrialized countries. Brazil is the seventh country with the highest rate of mercury in the *** major input of Hg to ecosystems is through atmospheric deposition（wet and dry）, being transported in the atmosphere over large distances. The forest biomes are of strong importance in the atmosphere/soil cycling of elemental Hg through foliar uptake and subsequent transference to the soil through litter, playing an important role as sink of this element. Soil microarthropods are keys to understanding the soil ecosystem, and for such purpose were characterized by the soil fauna of two Units of Forest Conservation of the state of the Rio de Janeiro, inwhich one of the areas suffer quite interference from petrochemicals and industrial anthropogenic activities and other area almost exempts of these perturbations. The results showed that soil and litter of the Atlantic Forest in Brazil tend to stock high mercury concentrations, which could affect the abundance and richness of soil fauna, endangering its biodiversity and thereby the functioning of ecosystems.

关键词： Biodiversity Litter Microarthropods Soil Trace-element

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Uncertainty in sap flow of Brazilian mahogany determined by the heat ratio method

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Journal of Forestry Research 2021年第4期32卷 1457-1466页

作者： Alisson Macendo Amaral Frederico Antonio Loureiro Soares lucas Melo Vellame Marconi Batista teixeira Federal Institute North of Minas Gerais(IFNMG) Campus ArinosMG-202 RoadKm 407ArinosMinas Gerais 38.680-000Brazil Federal Institute of Goiano(IF Goiano) Campus Rio VerdeSul Goiana RoadMailbox 66Rio VerdeGoiás 75.901-970Brazil Center for Agricultural Sciences Biological and EnvironmentalDepartment of Water Engineering and SoilFederal University of Bahia Reconcavo(UFRB)Rui Barbosa Street710Cruz das AlmasBahia 44380-000Brazil

The tropical arboreal species Brazilian mahogany(Swietenia macrophylla) is very important economically and ecologically,for which understanding ecophysiological variables such as sap flow will improve understanding of the species and its *** paper aims to measure uncertainties(U) involved in the application of the heat ratio method for determining sap flow in Brazilian mahogany using sets of heating probes and thermometers installed on plants of 18 months of age,cultivated in Yellow Latosol,under a weighing lysimeter and located in a protected *** uncertainty in sap flow was calculated as the combination of uncertainty in the thermal diffusivity(U_(k)),conductive section(U_(Sc)) and corrected sap velocity(U_(Vc)).U_(k) had greater weight in determining the flow of sap in Brazilian mahogany,when compared to U_(Sc) and U_(Vc).The thermal diffusivity during the cycle,or period evaluated,must be adjusted to improve the accuracy of the heat ratio method because the sap flow overestimated transpiration by 15.0%.When soil water was optimal In addition,the vapor pressure deficit linearly and indirectly influenced the SF with a difference of 14.6%.

关键词： Heat pulse Diffusivity Reliability Transpiration Vapor pressure deficit

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In vivo assessment of intratumoral aspirin injection to treat hepatic tumors

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World Journal of Hepatology 2013年第7期5卷 372-378页

作者： Rogério Saad-Hossne Fábio vieira teixeira Rafael Denadai Division of Coloproctology Department of Surgery Botucatu Medical School University of the State of So Paulo

AIM: To study the antineoplastic efficacy of 10% aspirin intralesional injection on VX2 hepatic tumors in a rabbit model. METHODS: Thirty-two male rabbits (age: 6-9 wk; body weight: 1700-2500 g) were inoculated with VX2 hepatic tumor cells (104 cells/rabbit) via supraumbilical median laparotomy. On day 4 post-implantation, when the tumors were about 1 cm in diameter, the rabbits were randomly divided into the following groups (n = 8 each group) to assess early (24 h) and late (7 d) antineoplastic effects of intratumoral injection of 10% bicarbonate aspirin solution (experimental groups) in comparison to intratumoral injection of physiological saline solution (control groups): group 1, 24 h control; group 2, 24 h experimental; group 3, 7 d control; group 4, 7 d experimental. The serum biochemistry profile (measurements of glycemia, alkaline phosphatase, gamma-glutamyl transferase, aspartateaminotransferase, and alanine aminotransferase) and body weight measurements were obtained for all animals at the following time points: D0, before tumor implant; D4, day of treatment; D5, day of sacrifice for groups 1 and 2; D11, day of sacrifice for groups 3 and 4. Gross assessments of the abdominal and thoracic cavities were carried out upon sacrifice. The resected liver tissues, including hepatic tumors, were qualitatively (general morphology, signs of necrosis) and quantitatively (tumor area) assessed by histopathological analysis. RESULTS: Gross examination showed no alterations, besides the left hepatic lobe tumors, had occurred in the thoracic and abdominal cavities of any animal at any time point evaluated. However, the features of the tumor foci were distinctive between the groups. Compared to the control groups, which showed normal unabated tumor progression, the aspirin-treated groups showed imprecise but limited tumor boundaries and a general red-white coloration (indicating hemorrhaging) at 24 h post-treatment, and development of yellow-white areas of a cicatricial as

关键词： Intralesional injection Intratumoral injection Aspirin Hepatic tumor VX2 Rabbit Antineoplastic Therapy

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Natural Mg silicates with different structures and morphologies: Reaction with K to produce K2MgSiO4 catalyst for biodiesel production

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International Journal of Minerals,Metallurgy and Materials 2020年第1期27卷 46-54页

作者： Fabiane Carvalho Ballotin Mayra Nascimento Sara Silveira vieira Alexandre Carvalho Bertoli Ottávio Carmignano Ana Paula de Carvalho teixeira Rochel Montero Lago Departamento de Química Universidade Federal de Minas GeraisBelo HorizonteBrasil Doutorado Inovação/Mineradora Pedras Congonhas Universidade Federal de Minas Gerais31270-901 Belo Horizonte-MGBrazil

In this work, different magnesium silicate mineral samples based on antigorite, lizardite, chrysotile(which have the same general formula Mg3Si2O5(OH)4), and talc(Mg3Si4O10(OH)2) were reacted with KOH to prepare catalysts for biodiesel production. Simple impregnation with 20 wt% K and treatment at 700–900°C led to a solid-state reaction to mainly form the K2MgSiO4 phase in all samples. These results indicate that the K ion can diffuse into the different Mg silicate structures and textures, likely through intercalation in the interlayer space of the different mineral samples followed by dehydroxylation and K2MgSiO4 formation. All the materials showed catalytic activity for the transesterification of soybean oil(1:6 of oil : methanol molar ratio, 5 wt% of catalyst, 60°C). However, the best results were obtained for the antigorite and chrysotile precursors, which are discussed in terms of mineral structure and the more efficient formation of the active phase K2MgSiO4.

关键词： silicate serpentinite lizardite antigorite talc chrysotile biodiesel

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Pork Meat Quality of Preto Alentejano and Commercial Largewhite Landrace Cross

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Journal of Integrative Agriculture 2013年第11期12卷 1961-1971页

作者： Alfredo teixeira Sandra Rodrigues Veterinary and Animal Reserch Centre (CECAV) Agrarian School of Polytechnic Institute of BraganaCampus Sta Apolónia Apt.1172Bragan a 5301-855Portugal Mountain Research Centre(CIMO) Agrarian School of Polytechnic Institute of BraganaCampus Sta Apolónia Apt.1172Bragan a 5301-855Portugal

This work aimed to evaluate the physical-chemical characteristics of pork from a local breed （Portuguese black pork called Preto Alentejano） and a commercial breed. Sixteen animals were used, 4 females and 4 males from each breed. Animals had 80-100 kg of live weight. The longissimus muscle between the 5th thoracic vertebra and the 10th lumbar vertebra was used in the analysis. Samples were analysed for protein, fat, pigments, ashes, dry mater, water-holding capacity, and texture. Results of fat and pigments contents indicate signiifcant （P〈0.05 and P〈0.01） differences for all treatments. For protein, ashes, dry mater, water-holding capacity and texture, no signiifcant differences were found for sex. In the analysis of fatty acids composition, ten were detected, being the main ones C16：0, C18：0, C16：1, C18：1, C18：2. There was a predominance of monounsaturated fatty acids （MUFA）, followed by saturated （SFA） and polyunsaturated （PUFA）. Differences were signiifcant for sex （P〈0.01） and breed （P〈0.01）. Preto Alentejano breed and females presented the higher percentages of SFA （P〈0.01） and MUFA （P〈0.001） fatty acids. Differences between breeds might be due to breed production system and feed differences.

关键词： breed sex pork meat quality

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Oxidative stress in N88S seipinopathy:novel insights into the mechanisms of neurodegeneration and therapeutic avenues

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Neural Regeneration Research 2023年第8期18卷 1719-1720页

作者： Vítor Costa Vitor teixeira i3S-Instituto de Investigação e Inovação em Saúde Universidade do PortoPortoPortugal Yeast Signalling Networks IBMC-Instituto de Biologia Molecular e CelularUniversidade do PortoPortoPortugal ICBAS Instituto de Ciências Biomédicas Abel SalazarUniversidade do PortoPortoPortugal

Lipid droplets (LDs) are ubiquitous cellular orga nelles that perform functions mostly dedicated to energy homeostasis and lipid *** neutral lipid depots (triacylglycerol,sterol esters),they can be rapidly mobilized through lipase-mediated hydrolysis (lipolysis) or via lipophagy,a specific form of autophagy devoted to consumption of LDs inside the lysosome.

关键词： hydrolysis insight devoted

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Flow regimes in wet conical spouted beds using glass bead mixtures

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Particuology 2008年第2期6卷 72-80页

作者： Marcelo S.Bacelos Jos teixeira Freire Universidade Federal de Sāo Carlos Centro de Ciências Exatas e de TecnologiaPrograma de Pós-Graduacāo em Engenharia QuímicaCentro de Secagem de PastasSuspensōes e SementesRod.Washington LuizKm 23513565-905CP 676Sāo CarlosSPBrazil

Using a high-viscosity Newtonian fluid, glycerol, an experimental investigation was carried out to evaluate the stable spouting regime in conical spouted beds using four particle mixtures： a reference （monoparticles）, a binary mixture, two ternary mixtures with flat and Gaussian distributions respectively. The mixtures were selected for particle diameters （dp） ranging from 1.09 to 4.98 mm and particle diameter ratios （dpL/dps） ranging from 1.98 to 4.0. Experimental data show that pressure fluctuation signals of the bed, as indicated by changes in their standard deviations, provide suitable information to identify the range of operational conditions for stable spouting. However, the analysis of skewness of curves of pressure fluctuation as a function of air velocity appears not sufficient to identify a particular flow regime. For glycerol in the spouting regime, the standard deviation is noted to increase with increasing glycerol concentration due to the growth of interparticle forces. The implications of these research findings on the drying of suspensions in conical spouted beds using glass bead mixtures are also discussed.

关键词： Conical spouted bed Binary and ternary mixtures Processing of pastes Spouting regimes Spouting stability Pressure fluctuation

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Nutrient variability and its influence on nitrogen processes in a highly turbid tropical estuary(Bangpakong, Gulf of Thailand)

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Journal of Environmental Sciences 2016年第7期28卷 131-142页

作者： Adriano A.Bordalo Kashane Chalermwat Catarina teixeira Laboratory of Hydrobiology and Ecology Institute of Biomedical Sciences University of Porto Centre of Marine and Environmental Research University of Porto Department of Aquatic Sciences Burapha University

Estuarine ecosystems in SE Asia have been poorly studied when compared to other tropical environments. Important gaps exist particularly in the understanding of their biogeochemical function and contribution to global change. In this work we looked into N-turnover in the water column and sediments of the Bangpakong estuary（13°N）. A seasonal sampling program was performed along the salinity gradient covering different stretches of the estuary（68 km）.Key physical and chemical characteristics were also monitored in order to unravel possible environmental controls. Results showed the occurrence of active denitrification in sediments（5.7–50.9 nmol N-N2/（cm3·hr））, and water column（3.5–1044 pmol N-N2/（cm3·hr））. No seasonal or spatial variability was detected for denitrification potential in sediment samples. However, in the water column, the denitrification activity peaked during the transition season in the downstream sites coinciding with high turbidity levels. Therefore, in that period of the year, the water column compartment may be an important contributor to nitrate reduction within the estuary. The rather low nitrification rates detected were not always measurable, probably due to the reduced oxygen content and high siltation. This study is one of the few dealing simultaneously with sediments and water column processes in a highly turbid tropical ***, it emerges as a valuable contribution for the understanding of the dynamics of the nitrogen cycle in tropical environments by exploring the role of estuarine N microbial activity in reducing the effects of increased nitrogen loads.

关键词： Nutrients Denitrification Nitrification Tropical estuary Bangpakong River

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