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营造感性、好动的“豹力美学”JAGUAR E-PACE设计鉴赏

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汽车杂志 2018年第9期 120-120页

作者： lucas JAGUAR(Photo)

作为捷豹SUV家族旗下的新成员，E-PACE打开了捷豹新的设计大门。将英伦血统、仿生学理念、赛道基因与时尚个性融会贯通。形成令人眼前一亮的“豹力美掌”。

关键词：捷豹 PACE 设计感性鉴赏美学 SUV 仿生学

Photobiomodulation therapy for osteoarthritis: Mechanisms of action

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World Journal of Translational Medicine 2022年第3期10卷 29-42页

作者： Fábio Pericinoto Giolo Gabriel Silva Santos Victor Fontes Pacheco Stephany Cares Huber Kaue Franco Malange Bruno Lima Rodrigues Fernanda Bassora Tomas Mosaner Gabriel Azzini lucas Leite Ribeiro Carlos Amilcar Parada JoséFábio Santos Duarte Lana Department of Physical Therapy Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170Brazil Biomedical Science Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170Brazil Department of Orthopedics Brazilian Institute of Regenerative MedicineIndaiatuba 13334-170Brazil Neurobiology of Pain and Regenerative Medicine The University of CampinasCampinas 13083-862Brazil Department of Hematology The University of CampinasCampinas 13083-878Brazil

Photobiomodulation(PBM)is a non-invasive therapeutic modality with demonstrated effects in many fields related to regenerative *** the field of orthopedics,in particular,PBM at various wavelengths has demonstrated the capacity to trigger multiple biological effects associated with protective mechanisms in musculoskeletal *** articles cited in this review show that devices operating close to or within the near infrared range at low intensities can provoke responses which favor the shift in the predominant catabolic microenvironment typically seen in degenerative joint diseases,especially osteoarthritis(OA).These responses include proliferation,differentiation and expression of proteins associated with stable cell ***,PBM can also modulate oxidative stress,inflammation and pain by exerting regulatory effects on immune cells and blocking the transmission of pain through sensory neuron fibers,without adverse ***,these effects are essential in order to control the progression of OA,which is in part attributed to exacerbated inflammation and degradative enzymatic reactions which gradually contribute to the destruction of joint *** may offer medical experts ease of application,financial viability,efficacy and lack of serious adverse ***,it may prove to be a suitable ally in the management of mild to moderate degrees of *** review explores and discusses the principal biological mechanisms of PBM and how the produced effects may contribute to the amelioration of osteoarthritic *** was reviewed using PubMed and Google Scholar in order to find studies describing the mechanisms of *** investigation included a combination of nomenclature such as:“photobiomodulation”,“phototherapy”,“laser therapy”,“PBM”,“osteoarthritis”,low level light therapy”,“inflammation”and“cartilage”.We considered only articles written in English,with access to the full text.

关键词： Photobiomodulation Low-level laser therapy Osteoarthritis Inflammation Regenerative medicine

Analysis of Unbalances Forces Using Methods of Identification and Finite Elements

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Journal of Mechanics Engineering and Automation 2014年第5期4卷 400-402页

作者： lucas Rangel de Oliveira Gilberto Pechoto de Melo Tiago Bemardes Firme Mariana Costa Falcao Department of Mechanic Engineering Universidade Estadual Paulista Julio de Mesquita Filho Ilha Solteira 15385-000 Brazil Department of Electrical Engineering Universidade Estadual Paulista Julio de Mesquita Filho llha Solteira 15385-000 Brazil

The study of damage in rotating machineries is of fundamental interest in the fields of machine and structure design. A rotating system, supported by bearings and under some dynamic conditions, can generate a variety of problems that are encountered in many different types of rotating machines. One of these problems is the unbalance due to non-homogeneous mass distribution along the shaft. One of the techniques which are widespread today is the identification of parameters and excitation forces that may well followed by monitoring the evolution and change of possible variations of these parameters. Although several methods for the identification of unbalance excitation force are available in the literature, none of them can be considered unrestricted to be applied for all rotating systems. In this study, two methodologies to identify unknown excitations, such as unbalance, have been proposed. This project refers to the analysis of unbalanced forces from displacement parameters and speed by using methods of identification by Fourier series and Legendre polynomials together with the finite element method, state observers in reasons of the problem of absence of signs of rotational displacement, bandpass filter were used to noise suppression of the data collected from the experimental part, Quasi-Newton method to minimize a function in which the bearing stiffness and its damping are unknowns, and also the experimental verification of the methodology, using for this system owned by a rotary mechanical vibrations of the Department of Mechanical Engineering of Faculty of Engineering, campus of Ilha Solteira.

关键词：不平衡力有限元方法鉴定方法力分析旋转机械旋转系统位移参数状态观测器

Virulence Factors in Methicillin-Resistant Staphylococcus aureus Isolated from ICU Units in Brazil

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Advances in Microbiology 2014年第4期4卷 207-215页

作者： simone G.Souza Guilherme B.Campos Pollianna S.Oliveira Daniel S.Sousa Danilo C.C.Da Silva Verena M.Santos Aline T.Amorim Angelita M.O.G.Santos Jorge Timenetsky Mariluze P.Cruz Regiane Yatsuda lucas M.Marques Instituto Multidisciplinar em Saúde Núcleo de Tecnologia em SaúdeUniversidade Federal da BahiaVitória da ConquistaBrazil Instituto de Ciências Biomédicas Departamento de MicrobiologiaUniversidade de Sao PauloSao PauloBrazil

Species of Staphylococcus are common in hospital infection (HI). Methicillin resistant S. aureus (MRSA) has also become a serious problem in Brazilian HI. The aim of this study was to characterize the pathogenicity of methicillin-resistant S. aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) isolated in public hospitals. The clinical isolates were obtained from intensive care unit. The MRSA and MSSA strains were genotyped by PCR for detection genes related to virulence factors. Moreover, the strains were tested for biofilm formation and cytokine induction in macrophages. Three strains of MRSA (9.68%) expressed the Sea gene, one (3.23%) Seb, 17 (54.84%) Spa and seven (22.58%) had PVL. Two MSSA strains (2.98%) expressed the Sea gene, three (4.48%) Seb, 18 (26.87%) Spa and 11 (16.42%) showed positive results for the PVL gene. There was no expression of Sec and CflA between MRSA and MSSA strains. Among MRSA and MSSA isolates, none statistical differences were observed in biofilm production. The analysis of cytokine induction in the inflammatory response of J774 macrophages by MRSA and MSSA isolates did not show statistical difference. Understanding the mechanisms of pathogenesis of S. aureus could provide important clues for both preventing and treating infection caused by these organisms.

关键词： MRSA MSSA Virulence Factor Hospitalar Infection

多种族民族个体的积极心理调适:种族歧视、社会支持和希望的预测作用

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多种族民族个体的积极心理调适:种族歧视、社会支持和希望的预测...

黑胫病弱毒种Leptosphaeria biglobosa通过不同的信号途径诱导油菜抗性

第二十一届全国心理学学术会议

作者：方圆程凯琳 Mingqi Li Olivia D.Chang Abigael G.lucas Jerin Lee K.Malulani Castro Savannah Pham Yena S.Purmasir Grace Y.Cho Jameson K.Hirsch Elizabeth L.Jeglic Edward C.Chang 北京师范大学心理学部 Department of Psychology University of Michigan Department of Psychology DePaul University Department of Psychology University of Maryland Department of Psychology Stanford University NYU Langone Medical Center Department of Psychology Harvard University Department of Psychology Southern Methodist University John Jay College of Criminal Justice

希望(hope)是积极心理调适(positive psychological adjustment)的有力预测因子,希望具有希望效能(hope agency)和希望路径(hope pathways)两种结构。前人研究显示,两种希望结构对积极心理调适具有不同的效果。本研究关注希望对多种族民... 详细信息

希望(hope)是积极心理调适(positive psychological adjustment)的有力预测因子,希望具有希望效能(hope agency)和希望路径(hope pathways)两种结构。前人研究显示,两种希望结构对积极心理调适具有不同的效果。本研究关注希望对多种族民族(multiethnoracial)个体积极心理调适的预测效果。多种族民族个体因为多重文化身份而经历着种族歧视(ethnoracial discrimination)和社会孤独,从而面临着更多的积极心理调适问题。研究通过对203个(女:164)多种族民族身份美国大学生进行量表研究,探讨希望对于积极心理调适的预测作用,并检验在控制了种族歧视和社会支持(social support)后,希望是否仍可以单独预测积极心理调适,且两种希望结构是否起到不同的效果。使用一般性种族歧视量表(GEDS)测量种族歧视,社会网络量表(SNL)中的两个问题测量社会支持(家人&朋友),希望量表(HS)测量希望的两个结构(希望效能&希望路径),主观活力量表(SVS)和生活满意度量表(SWLS)测量活力和生活满意度。结果显示,希望效能和希望路径与活力和生活满意度呈现显著正相关。层次回归结果显示:a.种族歧视单独负向预测生活满意度,无法预测活力;b.社会支持单独正向预测活力和生活满意度;c.控制了社会人口学变量、种族歧视和社会支持后,希望仍能单独正向预测活力和生活满意度;d.希望效能是活力的有力正向预测因子,而希望路径则更能有力正向预测生活满意度。本研究是首个强调希望对于多种族民族个体的重要作用的研究,结果可为对多种族民族个体进行积极心理调适的干预提供经验,即与消除种族歧视和增加社会支持相比,建立希望对多种族民族个体来说是更为现实易行的方法。

关键词：种族歧视社会支持希望心理调适多种族民族个体

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西北农林科技大学学报（自然科学版） 2005年第B8期33卷 257-257页

作者：刘胜毅刘仁虎 Akinwunmi O Latunde-Dada Hans Cools Huang Y J Bruce D L Fitt John A lucas 中国农业科学院油料作物研究所基因组与分子生物学研究室湖北武汉430062 Rothamsted Research HarpendenHertfordshire AL5 2JQUK

油菜黑胫病是由两种类型病原引起的,分别为A型强致病株(***)和B型弱致病株,B型现命名为一个新种***.本试验研究了弱致病株诱导的针对强致病株的抗性及其分子信号途径.

关键词：黑胫病诱导的系统抗性甘蓝型油菜病害防御反应基因

纤维肌痛患者自我取向与疼痛强度的关系:以自我同情作为应对机制

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纤维肌痛患者自我取向与疼痛强度的关系:以自我同情作为应对机制

Hypoglycemic Therapy in Chronic Hepatic Disease Literature Review

第二十一届全国心理学学术会议

作者：张宇佳叶洋铭 Edward C.Chang Abigael G.lucas Olivia D.Chang Harrison D.Angoff Mingqi Li Ashley H.Duong Judy Huang Marisa J.Perera Fuschia M.Sirois Jameson K.Hirsch 北京师范大学心理学部 University of Michigan Skidmore College University of Miami University of Sheffield East Tennessee State University

纤维肌痛是一种风湿病,该疾病往往表现出生理上的疼痛和心理上的不适。以往研究显示,一些积极的未来认知(如,乐观)与纤维肌痛的剧烈程度存在显著相关,未来取向作为其中的一个方面,可以描述患者在压力情境下的适应力。拥有积极未来取向... 详细信息

纤维肌痛是一种风湿病,该疾病往往表现出生理上的疼痛和心理上的不适。以往研究显示,一些积极的未来认知(如,乐观)与纤维肌痛的剧烈程度存在显著相关,未来取向作为其中的一个方面,可以描述患者在压力情境下的适应力。拥有积极未来取向的病人相信他们的情况在未来会好转,并感受到更低程度的疼痛。这两者之间的关系可能受到病人应对压力的方式影响。以往研究显示,自我同情是一种重要的应对机制,它是在压力时期指向自己的内在过程,包含三个正向维度(自我友善、普遍人性感和正念)和三个负向维度(孤立、自我批判和过度认同)。本研究以287名纤维肌痛患者为被试,考察了未来取向、纤维肌疼痛强度和自我同情之间的关系,并使用bootstrapping方法研究自我同情及其各维度在未来取向和纤维肌痛之间的中介作用。使用未来取向量表(Future Orientation Scale, FOS)测量未来取向;自我同情量表(Self-Compassion Scale, SCS)测量自我同情水平;纤维肌疼痛影响问卷修订版(Revised Fibromyalgia Impact Questionaire, FIQ-R)的第三部分测量被试近一周纤维肌疼痛症状的严重程度。实验结果表明:(1)未来取向与纤维肌痛之间存在显著的负相关;与自我同情的三个正向维度之间存在显著正相关;与自我同情的三个负向维度之间存在显著负相关。(2)自我同情的六个维度中只有孤立这一负向维度具有显著的间接效应,即在未来取向和纤维肌痛之间起中介作用。(3)将自我同情纳入模型之后,未来取向对纤维肌痛的预测不再显著,说明孤立是未来取向和纤维肌痛的完全中介。本研究说明,未来取向能显著预测纤维肌痛患者的疼痛程度,并且这种关系受自我同情中的一个特定维度,孤立的完全中介作用,即未来取向积极的患者会更少的思考与他人连结的缺失,进而体验到更轻的疼痛。

关键词：未来取向自我同情纤维肌痛疼痛成人

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Open Journal of Endocrine and Metabolic Diseases 2020年第10期10卷 137-146页

作者： Pedro Luis Imbeth-Acosta Nehomar Pájaro-Galvis Víctor Leal-Martinez Jorge Rico-Fontalvo Rodrigo Daza-Arnedo Orlando Castañeda-López María Cardona-Blanco Karen Mercado-Anillo José lucas-Daza Christian Perez-Calvo Jhonatan Hernández-Meza Álvaro Barraza-Pombo Marianela Florez-Ortega Jorge Hoyos-Fortich Isabella Uparella-Gulfo Blas de Lezo Clinic Cartagena Bolívar Colombia Faculty of Health Sciences University of Sinú Cartagena Bolívar Colombia New Bocagrande Hospital Cartagena Bolívar Colombia Colombian Association of Nephrology Medellín Colombia Colombian Association of Nephrology Cartagena Colombia Endocrinos SAS Cartagena Colombia Renal Unit B. Braun Medellín Antioquia Colombia University of Cartagena Cartagena Bolívar Colombia Colombian Association of Nephrology Ibagué Colombia Caribbean University Hospital Cartagena Colombia University of Sinu Cartagena Colombia Epidemiologist Blas de Lezo Clinic Cartagena Colombia Naval Hospital Cartagena Colombia Rafael Nuñ ez University Cartagena Colombia

Chronic liver disease (CLD) refers to a structural and functional change of the liver, which modifies the pharmacokinetics of multiple drugs, including hypoglycemic agents. This alteration depends on the severity degree of the liver disease, clinical characteristics of the patient, and comorbidities presence such as kidney disease and drug biochemistry. Insulin is considered a safe therapeutic strategy in patients with CLD, however, for many oral hypoglycemic agents, its use and dose adjustment will depend on the Child-Pugh score, based on the risk of hypoglycemia in this type of patient.

关键词： Cirrhosis Hypoglycemic Agents Pharmacokinetics (MesH)

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美国建筑师协会的贺信

世界建筑导报 2008年第3期23卷 80-80页

作者： Frank E.lucas 美国建筑师协会荣誉院士团

美国建筑师协会荣誉院士敬爱的冯纪忠教授：我非常荣幸的作为主席代表美国建筑师协会院士团向您致以最诚挚的祝贺!祝贺您从事建筑教育60周年。这是一个重要的里程碑，很少有人能够享受如此殊荣，如您一样长期而杰出的学术生涯。我们因... 详细信息

美国建筑师协会荣誉院士敬爱的冯纪忠教授：我非常荣幸的作为主席代表美国建筑师协会院士团向您致以最诚挚的祝贺!祝贺您从事建筑教育60周年。这是一个重要的里程碑，很少有人能够享受如此殊荣，如您一样长期而杰出的学术生涯。我们因为您是我们协会的荣誉院士而感到自豪，我们表达我们的祝愿，祝愿您身体健康，并不断取得新的成就。您是您的学生、同济大学和整个建筑界的杰出楷模，感谢您的教诲!多年来众多优秀的学子得益于您饱含深情、孜孜不倦的教诲，您深受您的学生和同事的爱戴，谨致以最崇高的敬意!

关键词：美国建筑师协会建筑教育学术生涯身体健康同济大学院士建筑界学生