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Application of machine learning techniques to simulate the evaporative fraction and its relationship with environmental variables in corn crops

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Ecological Processes 2022年第1期11卷 758-771页

作者： Terenzio Zenone luca vitale Daniela Famulari Vincenzo Magliulo National Research Council Institute for Agricultural and Forestry Systems in the MediterraneanP.Le Enrico Fermi 180055 PorticiItaly National Research Council CNR Institute for BioeconomyVia P.Gobetti10140129 BolognaItaly

Background:The evaporative fraction(EF)represents an important biophysical parameter reflecting the distribution of surface available *** this study,we investigated the daily and seasonal patterns of EF in a multi-year corn cultivation located in southern Italy and evaluated the performance of five machine learning(ML)classes of algorithms:the linear regression(LR),regression tree(RT),support vector machine(SVM),ensembles of tree(ETs)and Gaussian process regression(GPR)to predict the EF at daily time *** adopted methodology consisted of three main steps that include:(i)selection of the EF predictors;(ii)comparison of the different classes of ML;(iii)application,cross-validation of the selected ML algorithms and comparison with the observed ***:Our results indicate that SVM and GPR were the best classes of ML at predicting the EF,with a total of four different algorithms:cubic SVM,medium Gaussian SVM,the Matern 5/2 GPR,and the rational quadratic *** com-parison between observed and predicted EF in all four algorithms,during the training phase,were within the 95%confidence interval:the R^(2)value between observed and predicted EF was 0.76(RMSE 0.05)for the medium Gaussian SVM,0.99(RMSE 0.01)for the rational quadratic GPR,0.94(RMSE 0.02)for the Matern 5/2 GPR,and 0.83(RMSE 0.05)for the cubic SVM *** results were obtained during the testing *** results of the cross-validation analysis indicate that the R^(2)values obtained between all iterations for each of the four adopted ML algorithms were basically constant,confirming the ability of ML as a tool to predict ***:ML algorithms represent a valid alternative able to predict the EF especially when remote sensing data are not available,or the sky conditions are not *** application to different geographical areas,or crops,requires further development of the model based on different data sources of soils,climate,and cropping systems.

关键词： Energy flux Evapotranspiration Eddy covariance Artificial intelligence

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Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy

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World Journal of Stem Cells 2024年第1期16卷 7-18页

作者： vitale Miceli Department of Research Istituto Mediterraneo per i Trapianti e Terapie ad alta SpecializzazionePalermo 90127Italy

Mesenchymal stromal/stem cells(MSCs)have garnered significant attention in the field of regenerative medicine due to their remarkable therapeutic *** play a pivotal role in maintaining tissue homeostasis and possess diverse functions in tissue repair and recovery in various *** cells are charac-terized by easy accessibility,few ethical concerns,and adaptability to in vitro cultures,making them a valuable resource for cell therapy in several clinical *** the years,it has been shown that the true therapeutic power of MSCs lies not in cell engraftment and replacement but in their ability to produce critical paracrine factors,including cytokines,growth factors,and exosomes(EXOs),which modulate the tissue microenvironment and facilitate repair and regeneration ***,MSC-derived products,such as condi-tioned media and EXOs,are now being extensively evaluated for their potential medical applications,offering advantages over the long-term use of whole ***,the efficacy of MSC-based treatments varies in clinical trials due to both intrinsic differences resulting from the choice of diverse cell sources and non-standardized production *** address these concerns and to enhance MSC therapeutic potential,researchers have explored many priming strategies,including exposure to inflammatory molecules,hypoxic conditions,and three-dimensional culture *** approaches have optimized MSC secretion of functional factors,empowering them with enhanced immunomodulatory,angiogenic,and regenerative properties tailored to specific medical *** fact,various priming strategies show promise in the treatment of numerous diseases,from immune-related disorders to acute injuries and ***,in order to exploit the full therapeutic potential of MSC therapy,the most important challenge is to optimize the modulation of MSCs to obtain adapted cell therapy for specific clinical *** other words,to unlock t

关键词： Mesenchymal stromal/stem cells Therapeutic properties Paracrine effects Cell priming Cell-free therapies Regenerative medicine

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Interpreting siliciclastic sedimentation in the upper Paleozoic Mulargia-Escalaplano Basin(Sardinia, Italy):influence of tectonics on provenance

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Journal of Palaeogeography 2024年第1期13卷 18-34页

作者： luca G.Costamagna Sara Criniti Dipartimento di Scienze Chimiche e Geologiche Citadella UniversitariaBlocco A09042 Monserrato CAItaly Dipartimento di Ingegneria dell'Ambiente Universita della Calabria87036 Arcavacata di Rende CSItaly

Late to post-Variscan molassic basins of Late Pennsylvanian-Permian age are exposed in Sardinia(Italy). Here, the compositional and stratigraphic evolution of the Mulargia-Escalaplano sedimentary basin(central Sardinia) has been investigated to highlight how the tectono-magmatic processes have influenced the sedimentation. Ruditic and arenitic samples were collected along well-characterized stratigraphic sections to provide a new insight into the impact of the tectono-magmatic processes on siliciclastic sedimentation. As a result, the conglomerates are mainly clast-supported, petromictic, and thus immature, with no defined maturity trend upwards. Nevertheless, pebble composition changes in times from Variscan basement pebble-rich to volcanic rock-rich, as a consequence of the basin widening and the dismantling and reworking of the coeval volcanic activity. The sandstone composition clearly changes from quartzolithic to feldspatholithic upwards, as a response to the same change of feeding and reworking of the volcanic rocks. Occasionally, interbedded quartzolithic arenites suggest exceptional floods carrying debris from the far borders of the basin. Also, the immature sandstone composition has been interpreted as being controlled by a continuous supply of fresh debris and to a rapid burial rate. In addition, the disappearance of metaradiolarite(lydite AA) Paleozoic grains in the sandstone mineral suite could represent a distinctive marker of a progressive unroofing of the Variscan chain and a clastic supply from deeper tectonic units.

关键词： Petrography Stratigraphy Provenance Molassic basins Sardinia

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Well-Posedness of Stochastic Continuity Equations on Riemannian Manifolds

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Chinese Annals of Mathematics,Series B 2024年第1期45卷 81-122页

作者： luca GALIMBERTI Kenneth H.KARLSEN Department of Mathematical Sciences NTNU Norwegian University of Science and TechnologyN-7491 TrondheimNorway Department of mathematics University of OsloP.O.Box 1053BlindernN-0316 OsloNorway

The authors analyze continuity equations with Stratonovich stochasticity,■ρ+divh[ρo(u(t,x)+∑_(i=1)^(N)a_(i)(x)w_(i)(t))]=0defined on a smooth closed Riemannian manifold M with metric *** velocity field u is perturbed by Gaussian noise terms Wi(t),:WN(t)driven by smooth spatially dependent vector fields a1(x),...,aN(x)on *** velocity u belongs to L_(t)^(1)W_(x)^(1,2)with divh u bounded in Lf,for p>d+2,where d is the dimension of M(they do not assume div_(h) u∈L_(t,x)^(∞)).For carefully chosen noise vector fields ai(and the number N of them),they show that the initial-value problem is well-posed in the class of weak L^(2) solutions,although the problem can be ill-posed in the deterministic case because of concentration *** proof of this“regularization by noise”result is based on a L^(2) estimate,which is obtained by a duality method,and a weak compactness argument.

关键词： Stochastic continuity equation Riemannian manifold Hyperbolic equa-tion Non-smooth velocity field Weak solution Existence Uniqueness

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Prevention of hepatitis B reactivation in patients with hematologic malignancies treated with novel systemic therapies:Who and Why?

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World Journal of Gastroenterology 2024年第5期30卷 509-511页

作者： Matteo Tonnini Clara Solera Horna luca Ielasi Department of Medical and Surgical Sciences University of BolognaBologna 40138Italy Division of Internal Medicine Hepatobiliary and Immunoallergic DiseasesIRCCS Azienda Ospedaliero-Universitaria di BolognaBologna 40138Italy Infectious Disease Unit Azienda USL-IRCCS di Reggio EmiliaReggio Emilia 42123Italy Department of Internal Medicine Ospedale degli Infermi di FaenzaFaenza 48018Italy

The risk of reactivation in patients with chronic or past/resolved hepatitis B virus(HBV)infection receiving chemotherapy or immunosuppressive drugs is a wellknown *** indication of antiviral prophylaxis with nucleo(t)side analogue is given according to the risk of HBV reactivation of the prescribed *** the advent of new drugs is occurring in all the field of medicine,in the setting of hematologic malignancies the last few years have been characterized by several drug classes and innovative cellular *** novel therapies,there are few data about the rate of HBV reactivation and the decision of starting or not an antiviral prophylaxis could be ***,patients are often treated with a combination of different drugs,so evaluating the actual role of these new therapies in increasing the risk of HBV reactivation is *** results are now available,but further studies are still *** with chronic HBV infection[hepatitis B surface antigen(HBsAg)positive]are reasonably all ***/resolved HBV patients(HBsAg negative)are the actual area of uncertainty where it could be difficult choosing between prophylaxis and pre-emptive strategy.

关键词： Hepatitis B reactivation Hepatitis B virus Antiviral prophylaxis Hematologic malignancies Chimeric antigens receptor-T cell therapy Immune checkpoint inhibitors

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Improvement of Surface Mechanical and Tribological Characteristics of L-PBF Processed Commercially Pure Titanium through Ultrasonic Impact Treatment

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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 1034-1046页

作者： Iman Ansarian Reza Taghiabadi Saeid Amini Mohammad Hossein Mosallanejad luca Iuliano Abdollah Saboori Department of Materials Science and Metallurgy Imam Khomeini International University(IKIU)QazvinIran Department of Mechanical Engineering University of KashanKashanIran Integrated Additive Manufacturing Center Department of Management and Production EngineeringPolitecnico di TorinoCorso Duca Degli Abruzzi 2410129TurinItaly

Multi-pass ultrasonic impact treatment(UIT)was applied to modify the microstructure and improve the mechanical and tribological characteristics at the near-surface region of commercially pure Ti(CP-Ti)specimens produced by the laser powder bed fusion(L-PBF)*** considerably refined the L-PBF process-related acicular martensites(α′-M)and produced a well-homogenized and dense surface microstructure,where the porosity content of 1-,3-,and 5-pass UITed samples was reduced by 43,60,and 67%,*** UITed samples showed an enhancement in their near-surface mechanical properties up to a depth of about 300μ*** nanoindentation results for the 3-pass UITed sample revealed an increase of about 53,45,and 220%in its nanohardness,H/E_(r),and H_(3)/E_(r)^(2)indices,*** stylus profilometry results showed that performing the UIT removed the L-PBF-related features/defects and offered a smooth *** roughness average(R_(a))and the skewness(R_(sk))of the 3-pass UITed sample were found to be lower than those of the L-PBFed sample by 95 and 223%,*** the UIT also enhanced the material ratio,where the maximum load-bearing capacity(~100%)in as-L-PBFed(as-built)and 3-pass UITed samples was obtained at 60-and 10-µm depths,*** tribological investigations showed that applying the UIT resulted in a significant reduction of wear rate and average coefficient of friction(COF)of *** instance,under the normal pressures of 0.05 and 0.2 MPa,the wear rate and COF of the 3-pass UITed sample were lower than those of the L-PBFed sample by 65 and 58%,and 20 and 17%,respectively.

关键词： Laser powder bed fusion Ultrasonic impact treatment Commercially pure Ti(CP-Ti) Surface mechanical properties Tribological properties

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ZrB_(2)-SiC ceramics toughened with oriented paper-derived graphite for a sustainable approach

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Journal of Advanced Ceramics 2024年第2期13卷 207-219页

作者： luca Zoli Francesca Servadei Simone Failla Matteo Mor Antonio Vinci Pietro Galizia Diletta Sciti CNR-ISSMC Institute of ScienceTechnology and Sustainability for CeramicsFaenza I-48018Italy

Carbon fibre-reinforced ultra-high temperature ceramics(UHTCs)are considered a class of promising materials for several applications,the most appealing ones being in the aerospace *** is necessary to overcome the brittleness and low thermal shock resistance of ceramics and is often provided through the addition of carbon fibres or other carbon-based phases,such as nanotubes,graphene,and *** present work is focused on the toughening of UHTCs through incorporation of 30-50 vol% thin,ordered graphite layers from conventional filter paper followed by hot pressing *** filter paper was selected because it undergoes thermolysis with no melting stage forming a strong carbonaceous residue that can be used as *** and mechanical properties of toughened composites were compared to those of other materials reinforced with short carbon fibres and the effect of different distribution of graphite was *** of graphite allowed toughness to be increased from 3−4 MPa·m^(1/2)(for unreinforced materials)to 5.1−5.5 MPa·m^(1/2),similar to results obtained with short fibre *** high-temperature properties,such as strength and toughness as well as oxidation resistance at 1500℃,were also examined.

关键词： borides paper-derived graphite microstructure toughness sustainability

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Unravelling the ion transport and the interphase properties of a mixed olivine cathode for Na-ion battery

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Journal of Energy Chemistry 2024年第9期96卷 300-317页

作者： luca Minnetti Leonardo Sbrascini Antunes Staffolani Vittorio Marangon Francesco Nobili Jusef Hassoun School of Sciences and Technologies–Chemistry Division University of CamerinoVia Madonna delle Carceri ChIP62032 CamerinoItaly Current affiliation:University of Bologna Department of Chemistry“Giacomo Ciamician”Via Francesco Selmi 240126 BolognaItaly Graphene Labs Istituto Italiano di Tecnologiavia Morego 30Genoa 16163Italy Department of Chemical Pharmaceutical and Agricultural SciencesUniversity of FerraraVia Fossato di Mortara 1744121 FerraraItaly GISEL−Centro di Riferimento Nazionale per i Sistemi di Accumulo Elettrochimico di Energia INSTMFirenze 50121Italy National Interuniversity Consortium of Materials Science and Technology(INSTM)University of Ferrara Research Unit University of FerraraVia Fossato di Mortara1744121 FerraraItaly

The replacement of Li by Na in an analogue battery to the commercial Li-ion one appears a sustainable strategy to overcome the several concerns triggered by the increased demand for the electrochemical energy ***,the apparently simple change of the alkali metal represents a challenging step which requires notable and dedicated ***,we investigate herein the features of a NaFe_(0.6)Mn_(0.4)PO_(4)(NFMP)cathode with triphylite structure achieved from the conversion of a LiFe0.6Mn0.4PO4(LFMP)olivine for application in Na-ion *** work initially characterizes the structure,morphology and performances in sodium cell of NFMP,achieving a maximum capacity exceeding 100 mAh g^(−1)at a temperature of 55℃,adequate rate capability,and suitable retention confirmed by ex-situ ***,the study compares in parallel key parameters of the NFMP and LFMP such as Na^(+)/Li^(+)ions diffusion,interfacial characteristics,and reaction mechanism in Na/Li cells using various electrochemical *** data reveal that relatively limited modifications of NFMP chemistry,structure and morphology compared to LFMP greatly impact the reaction mechanism,kinetics and electrochemical *** changes are ascribed to the different physical and chemical features of the two compounds,the slower mobility of Na^(+)with respect to Li^(+),and a more resistive electrode/electrolyte interphase of sodium compared with ***,the study reveals analogue trends of the charge transfer resistance and the ion diffusion coefficient in NFMP and LFMP during the electrochemical process in ***,the NFMP achieved herein is suggested as a possible candidate for application in a low-cost,efficient,and environmentally friendly Na-ion battery.

关键词： NaFe_(0.6)Mn_(0.4)PO_(4)NFMP Olivine Na-ion lon transport Interphase

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Lower Continental Crusts Involved in the Alpine Orogeny:New Insight from the Santa Lucia Nappe Metasediments(Corsica,France)

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 904-920页

作者： Chiara FRASSI Maria DI ROSA luca PANDOLFI Michele MARRONI Dipartimento di Scienze della Terra Universitàdi PisaVia Santa Maria 5356126 PisaItaly Istituto di Geoscienze e Georisorse IGG-CNRVia Moruzzi50124 PisaItaly

In the Alpine Corsica(France),the Santa Lucia Nappe represents a peculiar unit preserving the unique relicts of Paleozoic lower to medium continental *** consists of composite basement affected by Permian granulite facies metamorphic conditions unconformably covered by a Late Cretaceous clastic sequence(Tomboni Conglomerate and Tralonca Flysch)affected by polyphase deformation and *** this work,we present a new reconstruction of the deformation events registered by the Tralonca Flysch during the Alpine *** D1 phase was testified by rare isoclinal *** D2 phase produced a continuous foliation and a map-scale sheath-fold with a top-to-W sense of *** D3 phase produced E-verging non-cylindrical folds and S3 crenulation cleavage that is not associated to metamorphic *** present the first temperature-pressure-deformation(P-T-d)path for the Tralonca Flysch,demonstrating that the Santa Lucia Nappe underwent accretion and then first stage exhumation in the Alpine wedge during the D1 phase with pressure and temperature peaks both occurred under blueschist metamorphic *** D2 phase occurred at lower pressure-temperature conditions during a second stage *** pressure-temperaturedeformation path is comparable with those of the Lower Units(i.e.,the subducted continental units of Alpine Corsica)suggesting a common geodynamic history.

关键词： blueschist-facies metamorphism P-T-d path Santa Lucia Nappe Corsica Alpine orogeny

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Impact of neoadjuvant multimodal therapy in the setting of locally advanced hepatocellular carcinoma

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World Journal of Gastroenterology 2024年第28期30卷 3452-3455页

作者： Daniele Ferraro Federica Falaschi luca Nazzaro Giovanni Vennarecci Hepato-biliary and Liver Transplant Centre Department of General Surgery and Woman’s HealthAORN Antonio CardarelliNaples 80131Italy

Immunotherapy and the implementation of more aggressive treatment schemes for locally advanced hepatocellular carcinomas have expanded the boundaries of curative *** of these advancements,patients who were once consid... 详细信息

关键词： Hepatocellular carcinoma Immunotherapy Radioembolization Chemoembolization Liver transplantation Liver resection

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