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Impact of dental and orofacial trauma on oral health-related quality of life in adults:A systematic review

Chinese Journal of Traumatology 2024年第5期27卷 249-253页

作者： Santosh Kumar Verma Awanindra Kumar Jha Om Prakash Subia Ekram Chandmani Tigga Mohammad Kashif Noorani Vini Mehta Aida Meto Agron Meto luca fiorillo Marco Cicciù Department of Periodontology&Oral Implantology Dental CollegeRajendra Institute of Medical SciencesRanchi834009JharkhandIndia Department of Orthodontic and Dentofacial Orthopedic Dental CollegeRajendra Institute of Medical SciencesRanchi834009JharkhandIndia Department of Oral and Maxillofacial Surgery Dental College Rajendra Institute of Medical SciencesRanchi834009JharkhandIndia Prosthodontics and Crown and Bridge and Oral Implantology 800001PatnaIndia Department of Public Health Dentistry Dr.D.Y.Patil Dental College and HospitalDr.D.Y.Patil VidyapeethPimpriPune411018MaharashtraIndia Department of Dentistry Faculty of Dental SciencesUniversity of Aldent1007TiranaAlbania Department of Biomedical and Dental Sciences Morphological and Functional ImagesUniversity of Messina98100MessinaItaly Multidisciplinary Department of Medical-Surgical and Dental Specialties Second University of Naples80100NaplesItaly Department of Surgery and Surgical Specialties University of Catania95100CataniaItaly

Purpose:Dental and orofacial trauma among the adult population constitutes a major public health *** impact is not just physical but also *** analyse the impacts of dental and orofacial trauma on oral health-related quality of life(OHRQoL)in adults and determine whether the 2 variables are closely ***:This is a systematic *** terms“dental trauma”,“orofacial trauma”,“oral health”,“oral health related impact life”,“OHRQoL”,“positive and negative affect scale”,“quality of life”,“facial injuries”,“adults”,and“young adults”were researched in the databases of PubMed,ScienceDirect,Scopus and Google Scholar for associated studies up to December 30,2022.A comprehensive search was designed and the articles were independently screened for eligibility by 2 *** included studies’author,year of publication,the country where the study was conducted,population demographics(number and age),an instrument used for assessing OHRQoL and the relevant result were recorded and *** quality of the evidence was assessed using Joanna Briggs Institute checklist for observational ***:Out of 482 unique records,3 articles were included for data *** studies were *** studies did not mention confounding *** scales were used for dental and orofacial trauma and *** has a directly proportional relationship with orofacial *** with orofacial trauma have a significant impact on this value with a prevalence of 88.4%.Conclusion:The highest impact on OHRQoL was seen immediately after the diagnosis of an orofacial *** impact increases with the severity of the ***,to promote overall dental and general health,health education initiatives should include information on the causes,prevention,and requirement for prompt responses by the populace in seeking dental intervention.

关键词： Dental trauma Oral health Oral health-related quality of life Orofacial trauma

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From mice to humans:a need for comparable results in mammalian neuroplasticity

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Neural Regeneration Research 2025年第2期20卷 464-466页

作者： Marco Ghibaudi Enrica Boda luca Bonfanti Neuroscience Institute Cavalieri Ottolenghi OrbassanoItaly Department of Veterinary Sciences University of TurinTurinItaly Department of Neuroscience Rita Levi-Montalcini University of TurinTurinItaly

Brain plasticity-A universal tool with many variations:The study of brain plasticity has been gaining interest since almost a century and has now reached a huge amount of information(>80,000 results in PubMed).Overall,different types of plasticity,including stem cell-driven genesis of new neurons(adult neurogenesis),cells in arrested maturation(dormant neurons),neuro-glial and synaptic plasticity,can coexist and contribute to grant plastic changes in the brain,from a cellular to system level(Benedetti and Couillard-Despres,2022;Bonfanti et al.,2023).

关键词： plasticity al. arrest

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Role of copper chelating agents: between old applications and new perspectives in neuroscience

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Neural Regeneration Research 2025年第3期20卷 751-762页

作者： Rosalba Leuci Leonardo Brunetti Vincenzo Tufarelli Marco Cerini Marco Paparella Nikola Puvača luca Piemontese Department of Pharmacy-Pharmaceutical Science University of Bari Aldo MoroBariItaly Department of Precision and Regenerative Medicine and Jonian Area(DiMePRe-J) Section of Veterinary Science and Animal ProductionUniversity of Bari Aldo MoroBariItaly Department of Engineering Management in Biotechnology Faculty of Economics and Engineering Management in Novi SadUniversity Business Academy in Novi SadNovi SadSerbia

The role of copper element has been an increasingly relevant topic in recent years in the fields of human and animal health, for both the study of new drugs and innovative food and feed supplements. This metal plays an important role in the central nervous system, where it is associated with glutamatergic signaling, and it is widely involved in inflammatory processes. Thus, diseases involving copper(Ⅱ) dyshomeostasis often have neurological symptoms, as exemplified by Alzheimer's and other diseases(such as Parkinson's and Wilson's diseases). Moreover, imbalanced copper ion concentrations have also been associated with diabetes and certain types of cancer, including glioma. In this paper, we propose a comprehensive overview of recent results that show the importance of these metal ions in several pathologies, mainly Alzheimer's disease, through the lens of the development and use of copper chelators as research compounds and potential therapeutics if included in multi-target hybrid drugs. Seeing how copper homeostasis is important for the well-being of animals as well as humans, we shortly describe the state of the art regarding the effects of copper and its chelators in agriculture, livestock rearing, and aquaculture, as ingredients for the formulation of feed supplements as well as to prevent the effects of pollution on animal productions.

关键词： agriculture Alzheimer's disease chelators copper feed supplements multi-target

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Case study for investigating groundwater and the future of mountain spring discharges in Southern Italy

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Journal of Mountain Science 2017年第9期14卷 1791-1800页

作者： Nazzareno DIODATO Gianni BELLOCCHI Francesco fiorillo Gerardo VENTAFRIDDA Science and Technology Department University of Sannio 82100 Benevento Italy Met European Research Observatory 82100 Beneuento Italy UMR Ecosysteme Frairial INRA VetAgro Sup 63000 Clermont-Ferrand France Acquedotto Pugliese S.p.A. 70121 Bari Italy

Groundwater extraction is used to alleviate drought in many habitats. However, widespread drought decreases spring discharge and there is a need to integrate climate change research into resource management and action. Accurate estimates of groundwater discharge may be valuable in improving decision support systems of hydrogeological resource exploitation. The present study performs a forecast for groundwater discharge in Aquifer?s Cervialto Mountains(southern Italy). A time series starting in 1883 was the basis for longterm predictions. An Ensemble Discharge Prediction(EDis P) was applied, and the progress of the discharge ensemble forecast was inferred with the aid of an Exponential Smoothing(ES) model initialized at different annual times. EDisP-ES hindcast model experiments were tested, and discharge plume-patterns forecast was assessed with horizon placed in the year 2044. A 46-year cycle pattern was identified by comparing simulations and observations, which is essential for the forecasting purpose. ED is P-ES performed an ensemble mean path for the coming decades that indicates a discharge regime within ± 1 standard deviation around the mean value of 4.1 m^3 s^(-1). These fluctuations are comparable with those observed in the period 1961-1980 and further back, with changepoints detectable around the years 2025 and 2035. Temporary drought conditions are expected after the year 2030.

关键词： Caposele(Italy) Ground water Drought Ensemble forecast Exponential smoothing Spring discharge

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Factors that Influence Product Development and their Integration Level in Project Management Approaches

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Journal of Systems Science and Systems Engineering 2023年第4期32卷 462-482页

作者： luca Leib Faculty of Business and Economics Mendel University in BrnoBrnoCzech Republic

Project management literature provides various approaches to organize project ***,several factors influence product development about its efficiency and *** paper analyses the factors that affect product development and evaluates their integration level in project management concerning modern requirements imposed in a volatile,uncertain,complex,and ambiguous(VUCA)*** concludes by identifying undervalued influencing factors worth investigating in future research.

关键词： Communication decision making product development project management team organization VUCA

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DLC coatings for hydraulic applications

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中国有色金属学会会刊：英文版 2009年第4期19卷 810-813页

作者： luca NOBILI luca MAGAGNIN Dip. Chimica Materiali e Ingegneria Chimica ＂G. Natta＂ Politecnico di Milano Via Mancinelli 7-20131 Milano Italy

与水或低粘性的液体润滑油的代替在许多工业领域里是高度合乎需要的，由于环境、节俭的优点。水的低润滑可能为水力的部件的合适的操作是不够的，并且像钻石的碳(DLC ) 涂层作为稳固的润滑剂电影很吸引人。一个遥远血浆的 PACVD 过程被... 详细信息

与水或低粘性的液体润滑油的代替在许多工业领域里是高度合乎需要的，由于环境、节俭的优点。水的低润滑可能为水力的部件的合适的操作是不够的，并且像钻石的碳(DLC ) 涂层作为稳固的润滑剂电影很吸引人。一个遥远血浆的 PACVD 过程被利用扔 hydrogenated DLC 涂层(交流: H ) 在不同底层上。Microindentation 大小证明涂层坚硬在 35 GPa 附近。Tribological 行为被测试与氧化铝在水和水里执行了的 block-on-ring 评估。wear 率在由激光 profilemeter 测量 wear 体积以后被计算。wear 轨道的词法、组合的分析表明那涂层失败可以由磨料发生穿或分层，取决于底层性质。难、光滑的底层给最好的结果，驱散的氧化铝粒子增加 wear 率。

关键词：类金刚石涂层液压元件氧化铝颗粒应用等离子体辅助类金刚石碳固体润滑膜 CVD工艺

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Distal pancreatectomy in the new era of minimally invasive surgery: the on-going debate on the cost-effectiveness

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Hepatobiliary Surgery and Nutrition 2019年第6期8卷 659-661页

作者： Giuseppe Quero Claudio fiorillo Sergio Alfieri Digestive Surgery Unit Fondazione Policlinico Universitario A.Gemelli IRCCSCRMPG(Advanced Pancreatic Research Center)Largo A.GemelliRomeItaly UniversitàCattolica del Sacro Cuore Largo A.GemelliRomeItaly

We read with great interest the article of Rodriguez et al.,"Which method of distal pancreatectomy is cost-effective among open,laparoscopic,or robotic surgery?"(1).In the current climate of limited hospital sources and control of medical costs,the authors afford the interesting topic of the cost-effectiveness evaluation of the robot-assisted distal pancreatectomy(RDP)in comparison to the laparoscopic(LDP)and open approaches(ODP).To accomplish this purpose,they focused their attention on both the clinical and the economical outcomes of the three different techniques.

关键词： surgery al. cost

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Utilization of irradiance ratios for calculating the effect of reflections from obstructions in building energy simulation

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Building Simulation 2021年第4期14卷 945-967页

作者： Gian luca Brunetti Politecnico di Milano Department of Architecture and Urban Studies(DAStU)via Bonardi 320133MilanoItaly

The ability to take into account reflections from obstructions is of fundamental importance in building energy simulation (BES), because reflections can have a substantial influence on solar gains. In BES tools, this ability is often implemented duplicating functionalities that have already been solved efficiently in lighting simulation tools. This happens because importing those functionalities from a lighting simulation tool (source) into a BES tool (target) is usually a complex operation producing non-portable results. This article demonstrates that this ability can be imported modularly and portably without intervening in the internals of the two tools. This can be obtained by: (1) creating, in the source tool, pairs of models which are analogue-on the one hand-to the original model in the target tool, and-on the other hand-to the model in the target tool hypothetically enriched with some predictive ability only available in the source tool;(2) measuring, at each time step, the ratio between the performances predicted by the source tool as regards the two analogue models;(3) re-scaling, at each time-step, the performance predicted by the target tool on the basis of that ratio. When appropriate analogue models are utilized, this strategy enables distinct simulation tools to work like an integrated computing unit.

关键词： irradiance ratios shading factors analogue models solar reflections insolation factors

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Winter survival of microbial contaminants in soil:An in situ verification

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Journal of Environmental Sciences 2015年第1期27卷 131-138页

作者： Antonio Bucci Vincenzo Allocca Gino Naclerio Giovanni Capobianco Fabio Divino Francesco fiorillo Fulvio Celico University of Molise Department of Biosciences and Territory University "Federico Ⅱ" Department of Earth Sciences University of Sannio Department of Geological and Environmental Studies University of Parma Department of Physics and Earth Sciences "Macedonio Melloni"

The aim of the research was to evaluate, at site scale, the influence of freezing and freeze/thaw cycles on the survival of faecal coliforms and faecal enterococci in soil, in a climate change perspective. Before the winter period and during grazing, viable cells of faecal coliforms and faecal enterococci were detected only in the first 10 cm below ground, while,after the winter period and before the new seasonal grazing, a lower number of viable cells of both faecal indicators was detected only in some of the investigated soil profiles, and within the first 5 cm. Taking into consideration the results of specific investigations, we hypothesise that the non-uniform spatial distribution of grass roots within the studied soil can play an important role in influencing this phenomenon, while several abiotic factors do not play any significant role. Taking into account the local trend in the increase of air temperature, a different distribution of microbial pollution over time is expected in spring waters, in future climate scenarios. The progressive increase in air temperature will cause a progressive decrease in freeze/thaw cycles at higher altitudes, minimising cold shocks on microbial cells, and causing spring water pollution also during winter.

关键词： Climate change Cold shock Faecal indicator Freeze/thaw cycle Microbial contamination

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Historic recurrences in medicinal chemistry:nature-inspired structures as a new opportunity for novel multi-target anti-Alzheimer's drugs

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Neural Regeneration Research 2023年第12期18卷 2671-2672页

作者： luca Piemontese Universitàdegli Studi di Bari Aldo Moro Dipartimento di Farmacia-Scienze del Farmacovia E.OrabonaBariItaly

Alzheimer 's disease(AD) is an alarming noncommunicable, multi-factorial, and non-treatable disease. Its underlying neurodegenerative events have not yet been fully explained and its early diagnosis is very difficult. The appearance of the disease is associated with clinical features such as the degeneration of several cholinergic nuclei of the brain.

关键词： Alzheimer drugs diagnosis

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