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Management of ruptured hepatocellular carcinoma:Implications for therapy

World Journal of Gastroenterology 2010年第10期16卷 1221-1225页

作者： Nicolò Bassi Ezio Caratozzolo luca bonariol Cesare Ruffolo Alessio Bridda Luigi Padoan Michele Antoniutti Marco Massani IV Unit of Surgery Regional Reference Center of Hepato-Biliary-Pancreatic Surgery

AIM:To assess the treatment and tumor-related variables associated with outcome after treatment of spontaneously ruptured hepatocellular carcinoma (HCC).METHODS: Patients with ruptured HCC were identif ied. The complications, mortality and survival were assessed. The relationship between tumor size and the severity of hemoperitoneum and between tumor size and grade were examined.RESULTS: From January 1993 to January 2008, 556 patients with HCC with or without cirrhosis were evaluated; of which, 16 (2.87%) presented with spontaneous rupture. All but 1 patient had cirrhosis. Twelve patients underwent surgical resection while 4 underwent trans-cutaneous arterial catheter embolization (TAE) (trans-cutaneous arterial embolization). Early mortality (<30 d) was 25% (4 of 16) and was inversely relatedto Child-Pugh score; 3 of the 4 early deaths occurred in patients treated with TAE with 1 of 12 occurring in the resected group. There was no correlation between tumor size and grade or between size and severity of hemoperitoneum.CONCLUSION: Tumor size did not correlate with severity of the hemoperitoneum. There was an inverse relationship between G1-G3 (grade of cellular differentiation) HCC and dimensions.

关键词： Bleeding hepatocellular carcinoma Management of ruptured hepatocellular carcinoma Ruptured hepatocellular carcinoma

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Acute appendicitis: What is the gold standard of treatment?

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World Journal of Gastroenterology 2013年第47期19卷 8799-8807页

作者： Cesare Ruffolo Alain Fiorot Giulia Pagura Michele Antoniutti Marco Massani Ezio Caratozzolo luca bonariol Francesco Calia di Pinto Nicolò Bassi Ⅱ Deparment of Surgery (Ⅳ Unit) Regional Hospital "Ca’ Foncello"31100 TrevisoItaly

McBurney’s procedure represented the gold-standard for acute appendicitis until 1981,but nowadays the number of laparoscopic appendectomies has progressively increased since it has been demonstrated to be a safe procedure,with excellent cosmetic results and it also allows a shorter hospitalization,a quicker and less painful postoperative recovery.The aim of this editorial was to perform a review of the literature in order to address controversial issues in the treatment of acute appendicitis.

关键词： Acute appendicitis Surgery Laparoscopy

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