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Combined therapeutic approach:Inflammatory bowel diseases and peripheral or axial arthritis

World Journal of Gastroenterology 2009年第20期15卷 2469-2471页

作者： Fabiola Atzeni Sandro Ardizzone luca bertani Marco Antivalle Alberto Batticciotto Piercarlo Sarzi-Puttini Rheumatology Unit L. Sacco University Hospital Gastroenterology Unit L. Sacco UniversityHospital

Inflammatory bowel diseases(IBDs), particularly Crohn's disease(CD) and ulcerative colitis(UC), are associated with a variety of extra-intestinal manifestations(EIMs).About 36% of IBD patients have at least one EIM, which most frequently affect the joints, skin, eyes and the biliary tract.The EIMs associated with IBD have a negative impact on patients with UC and CD, and the resolution of most of them parallels that of the active IBD in terms of timing and required therapy;however, the clinical course of EIMs such as axial arthritis, pyoderma gangrenosum, uveitis, and primary sclerosing cholangitis is independent of IBD activity.The peripheral and axial arthritis associated with IBD have traditionally been treated with simple analgesics, non-steroidal anti-inflammatory drugs, steroids, sulfasalazine, methotrexate, local steroid injections and physiotherapy, but the introduction of biological response modifi ers such as tumor necrosis factor-α blockers, has led to further improvements.

关键词：溃疡性结肠炎综合治疗关节炎鸡传染性法氏囊病轴向炎症信息管理系统非甾体抗炎药

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Common bile duct lesions-how cholangioscopy helps rule out intraductal papillary neoplasms of the bile duct:A case report

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World Journal of Gastrointestinal Endoscopy 2020年第12期12卷 555-559页

作者： Helga bertaniEndoscopy Unit Silvia Cocca Giuseppe Grande luca Reggiani Bonetti Paolo Magistri Stefano Di Sandro Fabrizio DiBenedetto Rita Conigliaro Helga bertani Endoscopy Unit Azienda Ospedaliero-Universitaria di ModenaModena 41121MOItaly Department of Pathologic Anatomy University of Modena and Reggio EmiliaModena 41124MOItaly Hepato-pancreato-biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41124MOItaly

BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a rare variant of bile duct tumors,characterized by an exophytic growth exhibiting a papillary mass within the bile duct lumen and it can be localized anywhere along the biliary tree,with morphological variations and occasional invasion.CASE SUMMARY We present a patient with obstructive jaundice who was diagnosed with IPNB using cholangioscopy during endoscopic retrograde cholangio-pancreatography.Using the SpyGlass DS Ⅱ technology,we were able to define tumor extension and obtain targeted Spy-byte biopsies.After multidisciplinary evaluation,the patient was scheduled for surgical resection of the tumor,which was radically removed.CONCLUSION Cholangioscopy appears to be crucial for the rapid and clear diagnosis of lesions in the bile duct to achieve radical surgical resection.

关键词： Intraductal papillary neoplasm Cholangioscopy Bile duct Surgical resection SpyGlass Case report

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