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Tensegrity: A Novel Conceptual Framework for Rehabilitation of Functional Deficits for Breast Cancer Survivors

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Journal of Science in Sport and Exercise 2020年第3期2卷 215-219页

作者： Marjorie A.King Claudio L.battaglini Department of Physical Therapy Plymouth State UniversityMSC#6817 High StreetPlymouthNH 03264USA Department of Exercise and Sport Science University of North CarolinaChapel HillChapel HillNC 27599USA Lineberger Comprehensive Cancer Center University of North Carolina at Chapel HillChapel HillNC 27599USA

The current approach to breast cancer rehabilitation is currently narrowly focused on addressing resultant problems such as lymphedema or shoulder *** to rehabilitation are reactive responses to these *** a step back and looking at the breast cancer intervention in totality,it becomes apparent that steps could be taken to minimize or actu-ally prevent some of the ensuing functional problems by proactively treating a breast cancer *** than waiting for problems to arise,immediately post-intervention or ideally pre-intervention and throughout intervention referral of an individual to rehabilitation could provide a supportive role in the functional progression of the ***,while most orthopedic rehabilitation focuses on the function of a particular joint,with the extensive impact of the breast cancer treatments on the soft tissue of the body without any specific intervention at a joint,it is imperative that we begin to shift our rehabilitation approach to focusing on the alterations of the soft tissue prior to addressing any functional limitations in the joints,with the most common victim being the shoulder *** novel approach to breast cancer rehabilitation sug-gests initially addressing soft tissue *** these limitations begin to resolve as optimally as possible,secondary consideration is then given to functional limitations of a joint such as the shoulder joint.

关键词： Tensegrity Soft tissue Fascia Breast cancer rehabilitation

Effects of positive end-expiratory pressure on intracranial pressure,cerebral perfusion pressure,and brain oxygenation in acute brain injury:Friend or foe?A scoping review

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Journal of Intensive Medicine 2024年第2期4卷 247-260页

作者： Greta Zunino Denise battaglini Daniel Agustin Godoy IRCCS Ospedale Policlinico San Martino GenovaItaly Dipartimento di Scienze Diagnostiche e Chirurgiche Integrate Universitàdegli Studi di GenovaGenovaItaly Neurointensive Care Unit Sanatorio PasteurCatamarcaArgentina

Background Patients with acute brain injury(ABI)are a peculiar population because ABI does not only affect the brain but also other organs such as the lungs,as theorized in brain–lung crosstalk *** patients often require mechanical ventilation(MV)to avoid the complications of impaired respiratory function that can follow ABI;MV should be settled with meticulousness owing to its effects on the intracranial compartment,especially regarding positive end-expiratory pressure(PEEP).This scoping review aimed to(1)describe the physiological basis and mechanisms related to the effects of PEEP in ABI;(2)examine how clinical research is conducted on this topic;(3)identify methods for setting PEEP in ABI;and(4)investigate the impact of the application of PEEP in ABI on the *** The five-stage paradigm devised by Peters et *** expanded by Arksey and O'Malley,Levac et al.,and the Joanna Briggs Institute was used for *** also adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)extension *** criteria:we compiled all scientific data from peer-reviewed journals and studies that discussed the application of PEEP and its impact on intracranial pressure,cerebral perfusion pressure,and brain oxygenation in adult patients with *** criteria:studies that only examined a pediatric patient group(those under the age of 18),experiments conducted solely on animals;studies without intracranial pressure and/or cerebral perfusion pressure determinations,and studies with incomplete *** authors searched and screened for inclusion in papers published up to July 2023 using the PubMed-indexed online *** were presented in narrative and tubular *** The initial search yielded 330 references on the application of PEEP in ABI,of which 36 met our inclusion *** has recognized beneficial effects on gas exchange,but it produces hemodynamic changes that should be predicted to avoi

关键词： Acute brain injury Mechanical ventilation Positive end-expiratory pressure Intracranial pressure Brain-lung crosstalk Multimodal monitoring

The Effect of Familiarization on the Reliability of Isokinetic Assessment in Breast Cancer Survivors

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Journal of Science in Sport and Exercise 2020年第3期2卷 220-225页

作者： Filipe D.de Lima Claudio L.battaglini Sandro N.Chaves lucas Ugliara Jonathan Sarandy Martim Bottaro College of Health Sciences University of BrasiliaBrasiliaBrazil College of Education and Health Sciences University Center of BrasiliaBrasiliaBrazil Department of Exercise and Sport Science and Lineberger Comprehensive Cancer Center University of North Carolina at Chapel HillChapel HillUSA College of Physical Education University of BrasiliaBrasiliaDFBrazil Integrated College IESGO FormosaBrazil

Purpose To determine the amount of familiarization sessions required by breast cancer survivors to achieve a reliable meas-urement of muscle function assessed using isokinetic *** Twenty-six breast cancer survivors performed three isokinetic knee extension tests separated by,at least,48 *** isokinetic testing protocol included one warm-up set of 10 submaximal knee extensions at 120°/s,followed by two sets of four maximal knee extensions at 60°/s,with 2-min rest interval between *** torque(PT),time to peak torque(TPT),angle of peak torque(APT),and average power(AP)of each trial was used for the assessment of testing *** change in the mean,typical error,coefficient of variation and intraclass correlation coefficients(ICC2.1)were calculated to determine test-retest *** For PT,change in mean was lower between trials 2 and 3 than between trials 1 and 2(4.18% and 13.18%,respec-tively),and ICC was greater between trials 2 and 3 than between trials 1 and 2(0.962 and 0.818,respectively).For TPT and APT,ICC was clinically acceptable only between trials 2 and 3(0.757 and 0.803,respectively).For AP,change in mean was clinically acceptable between trials 2 and 3(9.84%),while ICC met acceptable reliability between both,trials 1 and 2 and,trials 2 and 3(0.756 and 0.891,respectively).Conclusion At least one familiarization session is adequate to achieve reliable measurements of muscle function using isokinetic dynamometry,while avoiding the impact of learning effect of the measurements in breast cancer survivors.

关键词： Muscle strength Breast cancer Isokinetic testing Resistance exercise Motor learning effect

Twenty-five years of research on the effects of exercise training in breast cancer survivors:A systematic review of the literature

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World Journal of Clinical Oncology 2014年第2期5卷 177-190页

作者： Claudio L battaglini Robert C Mills Brett L Phillips Jordan T Lee Christina E Story Marcelo GB Nascimento Anthony Carl Hackney Department of Exercise and Sport Science Christina StoryChapel Hill NC 27599 United States Lineberger Comprehensive Cancer Center Chapel Hill NC 27599 United States Exercise Oncology Research Laboratory University of North CarolinaChapel Hill NC 27599 United States Centro Universitario de Brasilia (UniCeub) SEPN 707/907-Campus do UniCEUB-Asa Norte-Brasília-DF-70790-075Brazil Department of Nutrition University of North Carolina at Chapel HillChapel Hill NC 27599 United States

AIM:To investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient ***:Pub Med, Medline Plus, the Cochrane Library, Web of Science, SportD iscus, Embase, Scorpus, and Google Scholar were searched from September to November 2013 to identify exercise training studies that used objective measurements of fitness and/or patient reported outcomes assessed pre and post-exercise training with statistical analyses performed in at least one of the following outcome measurements:Cardiorespiratory function, body composition, muscular strength, fatigue, depression, and overall quality of life. Five reviewers independently identified the studies that met the criteria for the review and discrepancies were resolved by consensus among all ***:Fifty-one studies were included in this review with 5 from the period between 1989-1999, 11 from 2000-2006, and 35 from 2007-2013. The evolution of study designs changed from aerobic only exercise training interventions(1989-1999), to a combination of aerobic and resistance training(2000-2006), to studies including an arm of resistance training or examining the effects of resistance training as the main mode of exercise(2007-2013). Overall, the benefits of exercise showed improvements in cardiorespiratory function, body composition, strength, and patient reported outcomes including fatigue, depression, and quality of ***:Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise.

关键词： Breast cancer Exercise training Complementary Alternative Medicine Oncology VO2peak Patients reported outcomes

Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome

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Journal of Intensive Medicine 2021年第1期1卷 42-51页

作者： Denise battaglini Marco Sottano Lorenzo Ball Chiara Robba Patricia R.M.Rocco Paolo Pelosi Anesthesia and Intensive Care San Martino Policlinico HospitalIRCCS for Oncology and NeuroscienceGenoa 16132Italy Department of Medicine University of BarcelonaBarcelona 08007Spain Department of Surgical Sciences and Integrated Diagnostics University of GenoaGenoa 16126Italy Laboratory of Pulmonary Investigation Carlos Chagas Filho Institute of BiophysicsFederal University of Rio de JaneiroRio de Janeiro 21941-901Brazil

Considerable progress has been made over the last decades in the management of acute respiratory distress syndrome(ARDS).Mechanical ventilation(MV)remains the cornerstone of supportive therapy for ***-protective MV minimizes the risk of ventilator-induced lung injury(VILI)and improves *** parame-ters contribute to the risk of VILI and require careful setting including tidal volume(V_(T)),plateau pressure(P_(plat)),driving pressure(ΔP),positive end-expiratory pressure(PEEP),and respiratory *** of energy and mechanical power allows quantification of the relative contributions of various parameters(V_(T),P_(plat),ΔP,PEEP,respiratory rate,and airflow)for the individualization of MV *** use of neuromuscular blocking agents mainly in cases of severe ARDS can improve oxygenation and reduce asynchrony,although they are not known to confer a survival *** respiratory therapies such as prone positioning,inhaled nitric oxide,and extracorporeal support techniques may be adopted in specific ***,respiratory weaning protocols should also be *** on a review of recent clinical trials,we present 10 golden rules for individualized MV in ARDS management.

关键词： Acute respiratory distress syndrome(ARDS) Protective mechanical ventilation Extracorporeal CO_(2)removal(ECCO_(2)R) Extracorporeal membrane oxygenation (ECMO)

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家兔人工授精技术的近期进展

草食家畜 1984年第2期 6-8页

作者： Marcella battaglini ,春牧

集约化养兔场的快速发展,促进了家兔人工授精技术的进步。使用人工授精可能达到的好处无疑是很多的。例如: 1.同期产仔,以便安排各种饲养操作,这样导致时间和劳力的节省,更好地实现全进-全出的生产方式;

关键词：人工授精技术家兔母兔精液保存人工输精

乳腺癌康复者预防上肢淋巴水肿运动处方的设计与实施

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中国护理管理 2021年第2期21卷 181-186页

作者：刘艳飞刘均娥麦艳华 Claudio battaglini 郭晨王婷婷首都医科大学护理学院北京市100069 香港理工大学护理学院美国北卡罗来纳大学教堂山分校莱恩伯格综合癌症中心福建师范大学体育科学学院首都医科大学附属北京世纪坛医院淋巴外科淋巴管疾病临床诊疗与研究中心

目的 :介绍乳腺癌康复者预防上肢淋巴水肿运动处方的构建与实施效果。方法 :从乳腺癌术后康复者的角度,利用最新的肌肉淋巴引流泵功能原理,提倡主动和适度的患侧上肢功能锻炼,采用质性研究中的深度访谈和参与性观察法,开发了根植于康复... 详细信息

目的 :介绍乳腺癌康复者预防上肢淋巴水肿运动处方的构建与实施效果。方法 :从乳腺癌术后康复者的角度,利用最新的肌肉淋巴引流泵功能原理,提倡主动和适度的患侧上肢功能锻炼,采用质性研究中的深度访谈和参与性观察法,开发了根植于康复者生活经验的肢体功能锻炼和保护措施,丰富了淋巴水肿的预防性运动康复干预措施和经验。遵循运动处方的设计原则,开发了一套为期12周的乳腺癌康复者预防上肢淋巴水肿的运动处方,包括力量训练处方、有氧运动处方和柔韧性运动处方。采用非随机分组的类实验研究,招募到106例乳腺癌术后康复者,其中干预组56例(包括13例已出现上肢淋巴水肿的患者),实施预防上肢淋巴水肿运动处方。对照组50例,实施常规健康宣教。采用上肢淋巴水肿发生率、上肢肌肉力量、心肺耐力等指标评价运动处方的实施效果。结果 :与对照组比较,干预组乳腺癌康复者没有新发生上肢淋巴水肿,其上肢肌肉力量和心肺耐力较实施前均提高;入组时已有上肢淋巴水肿的患者,其水肿症状有所消退。结论 :预防上肢淋巴水肿的运动处方干预能够提高乳腺癌康复者的肌肉力量和心肺耐力,降低上肢淋巴水肿的发生风险,同时促进淋巴水肿患者的肢体康复。

关键词：乳腺癌淋巴水肿运动处方康复护理

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Editor Welcome

Journal of Science in Sport and Exercise 2020年第3期2卷 189-189页

作者： Claudio L.battaglini Department of Exercise and Sport Science Lineberger Comprehensive Cancer CenterUniversity of North Carolina at Chapel HillChapel HillUSA

This special issue of the Journal of Science in Sport and Exercise is devoted to scientific inquiry related to clinical exercise and sports *** article is authored by top researchers in the clinical exercise physiolog... 详细信息

关键词： Welcome devoted sports

Impact of community-based exercise program participation on aerobic capacity in women with and without breast cancer

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World Journal of Clinical Oncology 2021年第6期12卷 468-481页

作者： Jordan T Lee Chad W Wagoner Stephanie A Sullivan Dean J Amatuli Kirsten A Nyrop Erik D Hanson Lee Stoner Brian C Jensen Hyman B Muss Claudio L battaglini Department of Exercise and Sport Science University of North Carolina at Chapel HillChapel HillNC 27599United States Lineberger Comprehensive Cancer Center University of North Carolina at Chapel HillChapel HillNC 27599United States Department of Medicine Division of CardiologyUniversity of North Carolina at Chapel HillChapel HillNC 27599United States Lineberger Comprehensive Cancer Center University of North CarolinaChapel HillNC 27599United States

BACKGROUND Evidence for exercise as an efficacious strategy to improve aerobic capacity of breast cancer survivors(BCS)has come largely from intervention studies conducted in laboratory *** is an increasing need to translate to community-type settings,but the efficacy of those interventions using gold standard evaluation is not *** To investigate whether similar improvement in aerobic capacity(maximal oxygen consumption[VO2])measured with gold standard testing can be achieved through a community-based setting in *** A peak cardiopulmonary exercise test(VO2peak),6-min walk test(6MWT),and timed up and go test(TUG)were assessed pre-and post-16 wk of progressive intensity aerobic and strength training exercise at a community *** The sample consisted of 31 early BCS(<1 year since treatment completion)and 15 controls(CTLs).Both groups significantly improved VO2peak(+1.2 mL/kg/min;P=0.030),6MWT(+35 meters;P<0.001),and TUG(-0.44 s;P<0.01)following *** groups improved peak cycling power during the cardiopulmonary exercise test with BCS improving by+10 watts more than the CTLs(P=0.020).Average exercise attendance was 71%(34 of 48 possible days),but compliant days averaged only 60%of total days for aerobic,and<40%for strength in both *** Community-based exercise programs can be an effective strategy to improve aerobic capacity and physical function for early-stage BCS but potentially not to the same extent observed in laboratory-based randomized controlled *** research is needed to explore barriers and facilitators of exercise engagement in community-based centers to maximize training benefits for adults with cancer.

关键词： Aerobic capacity Breast cancer Community-based Exercise Physical function