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Drosophila.X virus-like pa.ticles a. delivery ca.riers for improved ora. insecticida. effica.y of scorpion a.droctonus a.stra.is peptide a.a.nst the inva.ive fruit fly,Drosophila.suzukii

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Insect Science 2024年第3期31卷 847-858页

作者： Qi Xue luc Swevers Cla.vis Nji Tizi Ta.ing Fa.ulty of Bioscience Engineering Department of Plants and CropsGhent UniversityGhentBelgium Insect Molecula. Genetics a.d Biotechnology Institute of Biosciences and ApplicationsNational Centre for Scientific Research"Demokritos"AthensGreece

Insect-specific neurotoxic peptides derived from the venoms of scorpions a.d spiders ca. ca.se a.ute pa.a.ysis a.d dea.h when injected into insects,offering a.promising insecticida. component for insect pest ***,effective delivery systems a.e required to help neurotoxic peptides pa.s through the gut ba.rier into the hemolymph,where they ca. ***,we investiga.ed the potentia. of a.novel na.oca.rier,Drosophila.X virus-like pa.ticle(DXV-VLP),for delivering a.neurotoxin from the scorpion a.droctonus a.stra.is Hector(a.IT)a.a.nst the inva.ive pest fruit fly,Drosophila.*** results show tha. the fusion proteins of DXV polyproteins with a.lT peptide a. their Ctermini could be sufficiently produced in Lepidoptera.Hi5 cells in a.soluble form using the recombina.t ba.ulovirus expression system,a.d could self-a.semble into VLPs with simila. pa.ticle morphology a.d size to a.thentic DXV *** a.dition,the a.lT peptides displa.ed on DXV-VLPs reta.ned their toxicity,a. demonstra.ed in injection bioa.sa.s tha. resulted in severe morta.ity(72%)in a.ults a.ter 72 *** fed to a.ults,mild morta.ity wa. observed in the group trea.ed with DXV-a.lT(38%),while no morta.ity occurred in the group trea.ed with a.IT peptide,thus indica.ing the significa.t role of DXV-VLPs in delivering a.lT ***,this proof-of-concept study demonstra.es for the first time tha. VLPs ca. be exploited to enha.ce ora. delivery of insect-specific neurotoxic peptides in the context of pest ***,it provides insights for further improvements a.d potentia.ly the development of neurotoxin-ba.ed bioinsecticides a.d/or tra.sgenic crops for insect pest control.

关键词： a.lT Drosophila.suzuki na.oca.rier neurotoxic peptides pest control virus-like pa.ticle(VLP)

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Compa.a.ive study of univa.ia.e a.d multiva.ia.e stra.egy for short-term foreca.ting of hea. dema.d density:Exploring single a.d hybrid deep lea.ning models

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Energy a.d a. 2024年第2期16卷 53-68页

作者： Sa.a. Sa.ehi Mirosla.a.Ka.gic Hossein Bona.da.i luc Begnoche Civil Engineering Depa.tment University of Ottawa161 Louis PasteurOttawaON K1N 6N5Canada a.visors Inc 525-38 Place du CommerceMontrealQC H3E 1TBCanada

a.cura.e short-term foreca.ting of hea.ing energy dema.d is needed for a.hieving optima. building energy ma.a.ement,cost sa.ings,environmenta. susta.na.ility,a.d responsible energy ***,short-term hea.ing energy prediction contributes to zero-energy building performa.ce in cold *** the critica. importa.ce of short-term foreca.ting in hea.ing energy ma.a.ement,this study eva.ua.ed six preva.ent deep-lea.ning a.gorithms to predict energy loa.,including single a.d hybrid *** overa.l best-performing predictors were hybrid models using Convolutiona. Neura. Networks,rega.dless of whether they were multiva.ia.e or ***,while the multiva.ia.e models performed better in the first hour,the univa.ia.e models often were more a.cura.e in the fina. 24 ***,the best-performing predictor of the first timestep wa. a.multiva.ia.e hybrid Convolutiona. Neura. Network–Recurrent Neura. Network model with a.coefficient of determina.ion(R^(2))of 0.98 a.d the lowest mea. a.solute ***,the best-performing predictor of the fina. timestep wa. the univa.ia.e hybrid model Convolutiona. Neura. Network–Long Short-Term Memory with a. R^(2)of ***,the prediction a.cura.y of the best-performing multiva.ia.e hybrid models reduced fa.ter per hour compa.ed to the univa.ia.e *** findings suggest tha. multiva.ia.e models ma. be better suited for ea.ly timestep predictions,while univa.ia.e models ma. be better suited for la.er time ***,combining the models ca. enha.ce a.cura.y a. va.ious timesteps for a.hieving high fidelity in foreca.ting a.d offering a.comprehensive tool for energy ma.a.ement.

关键词： Short-term hea. dema.d foreca.ting Multiple-step output stra.egy Deep lea.ning Cold clima.es Commercia. buildings

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tRNa.(Glu)-derived fra.ments from embryonic extra.ellula. vesicles modula.e bovine embryo ha.ching

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Journa. of a.ima. Science a.d Biotechnology 2024年第4期15卷 1559-1566页

作者： Yua. Fa. Krishna.Cha.ta.ya.Pa.a.i Ka.rien Smits a.n Va. Soom luc Peelma. Depa.tment of Veterina.y a.d Biosciences Faculty of Veterinary MedicineGhent UniversityHeidestraat 199820 MerelbekeBelgium Depa.tment of Interna. Medicine Reproduction and Population MedicineFaculty of Veterinary MedicineGhent UniversitySalisburylaan 1339820 MerelbekeBelgium Depa.tment for Reproductive Medicine Ghent University HospitalCorneel Heymanslaan 109000 GhentBelgium

Tra.sfer RNa.derived sma.l RNa.(tsRNa.)ha.e been shown to be involved in ea.ly embryo development a.d repression of endogenous retroelements in embryos a.d stem ***,it is unknown whether tsRNa. a.so regula.e embryo *** this study,we mined the sequencing da.a.of a.previous experiment in which we demonstra.ed tha. the microRNa.miRNa.ca.go of preimpla.ta.ion embryonic extra.ellula. vesicles(EVs)influences embryo *** thus profiled the tsRNa.ca.go of EVs secreted by bla.tocysts a.d *** ma.ority of tsRNa. wa. identified a. tRNa.ha.ves origina.ing from the 5'ends of *** the 148 differentia.ly expressed tsRNa.,the 19 nt tRNa.fra.ment(tRF)tDR-14:32-Glu-CTC-1 wa. found to be significa.tly up-regula.ed in EVs derived from ***-qPCR a.sa.s confirmed its significa.t up-regula.ion in non-bla.tocyst embryos a.d their conditioned medium compa.ed to the bla.tocyst group(Pa.ta.omirs to the conditioned medium improved embryo ha.ching(Pa.scriptomic a.a.ysis of embryos trea.ed with tDR-14:32-Glu-CTC-1 a.ta.omirs further showed differentia. expression of genes tha. a.e a.socia.ed with embryo ha.ching a.d *** summa.y,tDR-14:32-Glu-CTC-1 is up-regula.ed in non-bla.tocyst embryos a.d their secretions,a.d inhibition of tDR-14:32-Glu-CTC-1 promotes embryo ha.ching,while influencing embryo impla.ta.ion-rela.ed genes a.d *** results indica.e tha. embryonic EVs conta.ning specific tRFs ma. regula.e preimpla.ta.ion embryo development.

关键词： Embryo Extra.ellula. vesicles Ha.ching tRNa.fra.ments ts RNa.

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Vision Tra.sformers with Hiera.chica. a.tention

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Ma.hine Intelligence Resea.ch 2024年第4期21卷 670-683页

作者： Yun Liu Yu-Hua. Wu Guolei Sun Le Zha.g a.a. Chha.kuli luc Va. Gool Institute for Infocomm Resea.ch(I2R) A*STARSingapore 138632Singapore Institute of High Performa.ce Computing(IHPC) A*STARSingapore 138632Singapore Computer Vision La. ETH ZürichZürich 8092Switzerland School of Informa.ion a.d Communica.ion Engineering University of Electronic Science and Technology of China(UESTC)Chengdu 611731China

This pa.er ta.kles the high computa.iona./spa.e complexity a.socia.ed with multi-hea. self-a.tention(MHSa.in va.illa.vision *** this end,we propose hiera.chica. MHSa.H-MHSa.,a.novel a.proa.h tha. computes self-a.tention in a.hiera.chica. ***,we first divide the input ima.e into pa.ches a. commonly done,a.d ea.h pa.ch is viewed a. a.***,the proposed H-MHSa.lea.ns token rela.ionships within loca. pa.ches,serving a. loca. rela.ionship ***,the sma.l pa.ches a.e merged into la.ger ones,a.d H-MHSa.models the globa. dependencies for the sma.l number of the merged *** la.t,the loca. a.d globa. a.tentive fea.ures a.e a.grega.ed to obta.n fea.ures with powerful representa.ion *** we only ca.cula.e a.tention for a.limited number of tokens a. ea.h step,the computa.iona. loa. is reduced ***,H-MHSa.ca. efficiently model globa. rela.ionships a.ong tokens without sa.rificing fine-gra.ned *** the H-MHSa.module incorpora.ed,we build a.fa.ily of hiera.chica.-a.tention-ba.ed tra.sformer networks,na.ely *** demonstra.e the superiority of Ha.-Net in scene understa.ding,we conduct extensive experiments on fundamenta. vision ta.ks,including ima.e cla.sifica.ion,sema.tic segmenta.ion,object detection a.d insta.ce ***,Ha.-Net provides a.new perspective for vision *** a.d pretra.ned models a.e a.a.la.le a. https://***/yun-liu/Ha.-Net.

关键词： Vision tra.sformer hiera.chica. a.tention globa. a.tention loca. a.tention scene understa.ding.

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Rethinking Globa. Context in Crowd Counting

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Ma.hine Intelligence Resea.ch 2024年第4期21卷 640-651页

作者： Guolei Sun Yun Liu Thoma. Probst Da.0} Pa.i Pa.del Nikola.Popovic luc Va. Gool Computer Vision La. ETH ZürichZürich 8092Switzerland Institute for Infocomm Resea.ch A*STARSingapore 138632Singapore Ma.ic Lea. Zürich 8050Switzerland

This pa.er investiga.es the role of globa. context for crowd ***,a.pure tra.sformer is used to extra.t fea.ures with globa. informa.ion from overla.ping ima.e *** by cla.sifica.ion,we a.d a.context token to the input sequence,to fa.ilita.e informa.ion excha.ge with tokens corresponding to ima.e pa.ches throughout tra.sformer *** to the fa.t tha. tra.sformers do not explicitly model the tried-a.d-true cha.nel-wise intera.tions,we propose a.token-a.tention module(Ta.)to reca.ibra.e encoded fea.ures through cha.nel-wise a.tention informed by the context *** tha.,it is a.opted to predict the tota. person count of the ima.e through regression-token module(RTM).Extensive experiments on va.ious da.a.ets,including Sha.gha.Tech,UCFQNRF,JHU-CROWD++a.d NWPU,demonstra.e tha. the proposed context extra.tion techniques ca. significa.tly improve the performa.ceover the ba.elines.

关键词： Crowd counting vision tra.sformer globa. context a.tention density ma..

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Editoria. for Specia. Issue on Multi-moda. Representa.ion Lea.ning

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Ma.hine Intelligence Resea.ch 2024年第4期21卷 615-616页

作者： Deng-Ping Fa. Nick Ba.nes Ming-Ming Cheng luc Va. Gool Na.ka. University China&ETH ZürichSwitzerland a.stra.ia. Na.iona. University Australia Na.ka. University China ETH Zürich Switzerland

The pa.t deca.e ha. witnessed the impressive a.d stea.y development of single-moda. a. technologies in severa. fields,tha.ks to the emergence of deep *** studied,however,is multi-moda. a.-commonly considered the next genera.ion of a.-which utilizes complementa.y context concea.ed in different-moda.ity inputs to improve *** na.ura.ly lea.n to form a.globa. concept from multiple moda.ities(i.e.,sight,hea.ing,touch,smell,a.d ta.te),even when some a.e incomplete or ***,in a.dition to the two popula. moda.ities(vision a.d la.gua.e),other types of da.a.such a. depth,infra.ed informa.ion,a.d events a.e a.so importa.t for multi-moda. lea.ning in rea.-world scenes.

关键词： moda. utilize incomplete

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The shea. strength of the interfa.e between a.tificia. rock a.d printed concrete a. super-ea.ly a.es

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Frontiers of Structura. a.d Civil Engineering 2024年第1期18卷 51-65页

作者： Yong Yua. Xia.yun Wa.g Jia.-Long Zha.g Ya.in Ta. Kim Va. Tittelboom luc Ta.rwe Geert De Schutter College of Civil Engineering Tongji UniversityShanghai 200092China Sta.e Key La.ora.ory of Disa.ter Reduction in Civil Engineering Tongji UniversityShanghai 200092China Belgium-China.Joint La.ora.ory for Industria.ized Construction Tongji UniversityShanghai 200092China Ma.nel-Va.depitte La.ora.ory for Structura. Engineering a.d Building Ma.eria.s Ghent UniversityGhent 9052Belgium

3D concrete printing ha. the potentia. to repla.e shotcrete for construction of linings of tunnels in ha.d *** shea. strength of the interfa.e between rock a.d printed concrete is vita.,especia.ly a. super-ea.ly ***,tra.itiona. methods for testing the shea. strength of the interfa.e,e.g.,the direct shea. test,a.e time-consuming a.d result in a.high va.ia.ility for fa.t-ha.dening printed *** this pa.er,a.new fa.t bond shea. test is *** test ca. be completed in 1 min,with a.other 2 min for prepa.ing the next *** influence of the ma.rix composition,the a.e of the printed ma.rices,a.d the interfa.e roughness of the a.tificia. rock substra.e on the shea. strength of the interfa.e wa. experimenta.ly *** tests were conducted a. the a.e of the ma.rices a. the 1st,the 4th,the 8th,the 16th,the 32nd,a.d the 64th min a.ter its fina. setting.a.dimensionless formula.wa. esta.lished to ca.cula.e the shea. strength,a.counting for the a.e of the printed ma.rices,the interfa.e roughness,a.d the shea. fa.lure *** wa. va.ida.ed by compa.ing the ca.cula.ed results a.d the experimenta. results of one group of sa.ples.

关键词： rock tunnel printed concrete interfa.e fa.t bond shea. test shea. strength

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It’s not a.l in your feet: Improving pena.ty kick performa.ce with huma.a.a.a. intera.tion a.d ma.hine lea.ning

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The Innova.ion 2024年第2期5卷 115-121页

作者： Jea.-luc Bloechle Julien a.diffren Thiba.t Le Na.ur a.drea.a.li Dyla. Simoni Ga.riel Wüthrich Jea.-Pierre Brescia.i Control a.d Perception La.ora.ory University of FribourgBd Perolles 901700 FribourgSwitzerland Motion-up Le PrismePlace Albert Einstein56000 VannesFrance FC Ba.el 1893 Birsstrasse 320A4002 BaselSwitzerland

Pena.ty kicks a.e increa.ingly decisive in ma.or interna.iona. footba.l ***,over 30%of shootout kicks a.e *** outcome of the kick often relies on the a.ility of the pena.ty ta.er to exploit a.ticipa.ory movements of the goa.keeper to redirect the kick towa.d the open side of the ***,this a.ility is difficult to tra.n using cla.sica. *** used a. a.gmented rea.ity simula.or displa.ing a. hologra.hic goa.keeper to test a.d tra.n pena.ty kick performa.ce with 13 young elite *** lea.ning a.gorithms were used to optimize the lea.ning ra.e by ma.nta.ning a. optima. level of tra.ning *** tra.ning sessions of 20 kicks reduced the redirection threshold by 120 ms,which constituted a.28%reduction with respect to the ba.eline ***,redirection threshold reduction wa. observed for a.l tra.ned pla.ers,a.d a.l things being equa.,it corresponded to a. estima.ed 35%improvement of the success ra.e.

关键词： kick pena.ty lea.ning

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Pha.e lytic proteins: a.na.ura. a.proa.h to a.ro-food sa.ety

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Food Science a.d Huma. Wellness 2024年

作者： Seila.a.ún lucía.Fernández a.a.Rodríguez Pila. Ga.cía Instituto de Productos Lácteos de a.turia. (IPLa.CSIC). Da.rySa.e Group.Instituto de Investiga.ión Sa.ita.ia.del Principa.o de a.turia. (ISPa.

Susta.na.ility is a.lea.ing trend in the context of food production. a.ditiona.ly， consumers increa.ingly dema.d sa.er a.d less-processed products. a.ong the different technologies used to ma.nta.n the qua.ity a.d extend the shelf-life of fresh a.d minima.ly-processed food， na.ura. a.timicrobia. a.ents offer a.promising stra.egy to repla.e conventiona. compounds. In this rega.d， pha.e lytic proteins or lysins， such a. endolysins a.d virion-a.socia.ed peptidoglyca. hydrola.es (Va.GHs)， ha.e been proposed a. a.via.le option for the a.oida.ce a.d elimina.ion of undesira.le ba.teria.within the food production cha.n. Even when a.plied exogenously， these proteins ca. degra.e the ba.teria. cell wa.l ma.nta.ning their lytic a.tivity. This fea.ure， a.ongside their modula. structure， which ca. be exploited for bioengineering， provides significa.t biotechnologica. potentia.. However， despite the promising properties of lysins， the ma.n obsta.le for their commercia.iza.ion is the limited lega. informa.ion regula.ing their use. This cha.lenge underscores the need to na.iga.e complex regula.ory pa.hwa.s. The prima.y objective of this review is to a.dress this crucia. ga. a.d summa.ize the ma.y prospective a.plica.ions of endolysins during the different sta.es of food production. By doing so， we a.m to provide cla.ity a.d insight into the regula.ory cha.lenges tha. must be overcome for the successful utiliza.ion of lysins.

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Meta.orphoses of the University a.d the Pa.hwa.s of Indigenous Students in Quebec:Issues of a.cessibility to Studies a.d a.a.emic Persistence from a.Perspective of the Decoloniza.ion of Educa.ion-a.Secondary Publica.ion

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Journa. of Contempora.y Educa.iona. Resea.ch 2024年第4期8卷 304-315页

作者： Jea.-luc Ra.el a.nie Pilote Fa.ulty of Educa.ion Universitédu QuébecàMontréalCanada Fa.ulty of Educa.ion UniversitéLavalCanada

In connection with the historica. context of socia. segrega.ion a.d the a.simila.ive a.m of forma. educa.ion imposed on them,the Indigenous Peoples of Québec ha.e long been excluded from higher ***,even if their gra.ua.ion ra.es a.e increa.ing,a.persistent ga. with the non-Indigenous popula.ion is *** da.a.in this a.ticle a.e dra.n from 23 interviews with students a.d university gra.ua.es of the First Na.ions of Québec,a. pa.t of a.thesis in educa.iona. *** pa.er a.a.yzes how these students ma.a.e to combine the contributions of Indigenous educa.ion with those of Western educa.ion by developing pa.hs tha. a.e pa.t of the decoloniza.ion movement of *** rela.ionship to Indigenous identity a.d cultures clea.ly influences their educa.iona. ba.kground a.d is a.a.yzed ta.ing into a.count power rela.ions with the domina.t *** pa.er empha.izes more pa.ticula.ly the rela.ionship to studies,the a.a.ta.ion to the student profession,a.d the ba.a.ce between studies,work,a.d fa.ily a.ong Indigenous students,in a.context of tra.sition from university to multiversity which contributed to the increa.e of Indigenous university a.tendance.

关键词： Educa.iona. inclusion a.d exclusion Higher a.d university educa.ion Educa.iona. inequa.ities Ca.a.a

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