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Optimum Threshold Estimation of Thorax CT Scan for COVID-19 Diagnosis in a Single Center in Cameroon

Advances in Infectious Diseases 2023年第1期13卷 12-20页

作者： Anne Esther Njom Nlend Landry Bonyomo Serges Abogo Serges Nga Nomo luc meka Moise Nna Beatrice Meva’a Arsene Brunelle Sandie Christiane Nsahlai Essos Hospital Center Yaoundé Cameroon Health Ebene consulting Research Department Yaoundé Cameroon Higher Institute of Medical Technology Yaoundé Cameroon Ministry of Public Health Yaoundé Cameroon Faculty of Medicine and Biomedical Sciences Yaoundé Cameroon African Population and Health Research Center Yaoundé Cameroon

Objective: To evaluate the lung CT scan as a possible predictive diagnostic method for COVID-19 in the Cameroonian context. Methods: We designed a cross sectional study. Suspected cases of COVID-19 during the first wave at the national social insurance fund (NSIF) hospital were screened with both COVID-19 with lung CT scan and a PCR test. Univariate analysis was performed for sample description and multivariate analysis to assess the correlation between positive results for the PCR and other parameters. We estimated the optimum threshold of sensitivity/specificity, and area under curve using the empirical method and package. Results: A total of 62 suspected COVID-19 cases were recorded, predominantly males (Sex Ratio = 2.2) with a median age of 58.5 (IQR = 19.7). Among our 62 patients, 29 (46.8%) were confirmed COVID-19 cases with positive PCR results. All the patients had a thorax CT scan with a median impairment of 40% (IQR = 20%). The optimum threshold estimate for CT scan for COVID-19 infection diagnosis was 60% (95% CI = 25% - 80%). Overall, the sensitivity and specificity estimates were 0.30 (95% CI = 0.15 - 0.49) and 0.87 (95% CI = 0.70 - 0.96), respectively, leading to an Area Under Curve (AUC) estimate of 0.59 (95% CI = 0.46, 0.71). Conclusion: In this setting, lung CT scan was neither sensitive nor specific to predict COVID-19 disease.

关键词： COVID-19 CT Scan Lung Diagnosis

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Facial and Periorbital Emphysemas Following a Violent Sneezing: An Atypical Clinical Situation

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第3期11卷 136-142页

作者： Adèle-Rose Ngo Nyeki Caroline Mvilongo Esthelle Minka Ngom Valentin Fokouo Roger Meva’a Léonel Atanga Yannick Mossus Claudine Nkidiaka luc meka Abakar Taimou Serge Abogo David Mindja Olive Ngaba Godefroy Koki Francois Djomou Richard Njock ENT Ophthalmology and Stomatology Department Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Essos Hospital Center Yaoundé Cameroon Central Hospital of Yaoundé Yaoundé Cameroon ENT Department Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Douala General Hospital Douala Cameroon Bertoua Regional Hospital Bertoua Cameroon

Introduction: Facial emphysema is the presence of air in the subcutaneous tissues of the facial region. They can be clinically recognized by the crackling sensation felt when the affected area is palpated. Observation: The authors describe left orbito-facial emphysema that occurred after a violent sneezing episode in a 36-year-old patient. He had significant edema of the left facial and ipsilateral periorbital region associated with major emphysema and complete closure of the left eye. Nasal cavities endoscopy revealed inflammation of the distal orifice of the nasolacrimal duct. The clinical ophthalmologic examination performed in emergency showed left chemosis, slight ocular hypertonia of mechanical origin, and a slight decrease in visual acuity. Pupillary reflexes and retinography were normal. A craniofacial computed tomography (CT) revealed a significant left orbital emphysema, a fracture of the left medial orbital wall (ethmoidal lamina papyracea) with intraconal fat incarceration without entrapment of the medial rectus and significant air infiltration of all the left hemifacial soft tissues. A broad-spectrum antibiotic and anti-inflammatory treatment were instituted, as well as practical advice to prevent a recurrence. We observed progressive resorption of the edema with a return to the normal of the soft tissues and the palpebral cleft in 15 days. Conclusion: These atypical cases can be serious. It is essential to exclude signs of visual deficit and ocular compression. Multidisciplinary management is important.

关键词： Sneezing Orbital Fracture Emphysema Pneumorbitia

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ABOUT TWO TYPES OF MICROSTRUCTURES ADAPTED TO HEAT EVACUATION AND ELASTIC STRESS:SNOW FLAKES AND QUASI-CRYSTALS

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Acta Mathematica Scientia 2012年第1期32卷 84-108页

作者： luc Tartar Department of Mathematical Sciences Carnegie Mellon University

I first met Constantine Dafermos in August 1974, at a meeting at Brown University, where I was invited because my former advisor （Jacques-Louis LIONS） could not come, and he had proposed my name. I was happily surprised that Constantine greeted me as if he knew me well, and since for many years now I have considered him as if he was an older brother, I wonder when this feeling started.

关键词： ABOUT TWO TYPES OF MICROSTRUCTURES ADAPTED TO HEAT EVACUATION AND ELASTIC STRESS

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Developing molecular-level models for organic field-effect transistors

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National Science Review 2021年第4期8卷 167-180页

作者： Haoyuan Li Jean-luc Brédas School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Department of Chemistry and Biochemistry University of Arizona

Organic field-effect transistors(OFETs) are not only functional devices but also represent an important tool for measuring the charge-transport properties of organic semiconductors(OSs). Thus, efforts to understand the performance and characteristics of OFET devices are not only useful in helping achieve higher device efficiencies but also critical to ensuring accuracy in the evaluations of OS charge *** studies rely on OFET device models, which connect the measured current characteristics to the properties of the OSs. Developing such OFET models requires good knowledge of the charge-transport processes in OSs. In device active layers, the OS thin films are either amorphous(e.g. in organic light-emitting diodes and organic solar cells) or crystalline(e.g. those optimized for charge transport in OFETs). When the electronic couplings between adjacent OS molecules or polymer chain segments are weak, the charge-transport mechanism is dominated by hopping processes, which is the context in which we frame the discussion in this Review. Factors such as disorder, mobility anisotropy, traps, grain boundaries or film morphology all impact charge transport. To take these features fully into account in an OFET device model requires considering a nano-scale, molecular-level resolution. Here, we discuss the recent development of such molecular-resolution OFET models based on a kinetic Monte Carlo approach relevant to the hopping regime. We also briefly describe the applicability of these models to high-mobility OFETs,where we underline the need to extend them to incorporate aspects related to charge delocalization.

关键词： organic semiconductors charge transport kinetic Monte Carlo simulations mobility measurements gradual channel approximation

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Chronic epididymitis and Grade III varicocele and their associations with semen characteristics in men consulting for couple infertility

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Asian Journal of Andrology 2018年第4期20卷 360-365页

作者： Alejandro Oliva luc Multigner Center for Interdisciplinary Studies National University of Rosario Rosario 2000 Argentina University of Rennes Inserm EHESP Irset (Institut de recherche en sante environnement et travail) UMR_S 1085 Rennes F-35000 France

Chronic epididymitis and varicocele are frequently observed genital disorders in men consulting for couple infertility, but their impact on semen characteristics at the time of infertility consultation is still a matter of debate. We investigated 652 male partners of couples who had their first infertility consultation between 1999 and 2015 in Argentina. Men with chronic epididymitis （n = 253）, Grade III varicocele （n = 106）, and both conditions （n = 125） were compared with a control group （n = 168） composed of men without these disorders or any other recognized causes of male infertility. We showed that men who presented isolated chronic epididymitis were more likely to have high percentages of low sperm motility and abnormal sperm morphology as well as a high number of white blood cells. Men with isolated Grade III varicocele had low sperm production and motility and an increased percentage of abnormal sperm morphology. Finally, men who simultaneously presented chronic epididymitis with Grade III varicocele had a low sperm motility and increased percentage of abnormal sperm morphology as well as a high number of white blood cells. Physical examination of the genital organs may identify common disorders, potentially involved as causal factors of patient＇s infertility. These disorders are associated with specific seminal profiles that should help in identifying the best treatment from the available therapeutic options, effectiveness, safety, and allowing as much as possible natural conception.

关键词： couple subfertility epididymitis male factor infertility semen quality varicocele

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Flow field in air-sparged hydrocyclone

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中国有色金属学会会刊：英文版 1994年第3期4卷 30-35页

作者： Chu, Liangyin luc, Qian Northwestern Univ Shenyung China

ＦＬＯＷＦＩＥＬＤＩＮＡＩＲ－ＳＰＡＲＧＥＤＨＹＤＲＯＣＹＣＬＯＮＥＣｈｕ，Ｌｉａｎｇｙｉｎ；Ｌｕｏ，Ｑｉａｎ（ＭｉｎｅｒａｌＥｎｇｉｎｅｅｒｉｎｇＤｅｐａｒｔｍｅｎｔ，Ｐ．Ｏ．Ｂｏｘ１３９ＮｏｒｔｈｅａｓｔｅｒｎＵ... 详细信息

ＦＬＯＷＦＩＥＬＤＩＮＡＩＲ－ＳＰＡＲＧＥＤＨＹＤＲＯＣＹＣＬＯＮＥＣｈｕ，Ｌｉａｎｇｙｉｎ；Ｌｕｏ，Ｑｉａｎ（ＭｉｎｅｒａｌＥｎｇｉｎｅｅｒｉｎｇＤｅｐａｒｔｍｅｎｔ，Ｐ．Ｏ．Ｂｏｘ１３９ＮｏｒｔｈｅａｓｔｅｒｎＵｎｉｖｅｒｓｉｔｙ，Ｓｈｅｎｙａｎ...

关键词： air-sparged hydrocyclone flow field froth flotation centrifuge process

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Conformally flat, minimal, Lagrangian submanifolds in complex space forms

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Science China Mathematics 2022年第8期65卷 1641-1660页

作者： Miroslava Antić luc Vrancken Faculty of Mathematics University of BelgradeBelgrade 11000Serbia Laboratoire de Mathématiques pour l’Ingénieur Université Polytechnique Hauts-de-FranceValenciennes 59313France Departement Wiskunde Katholieke Universiteit LeuvenLeuven 3001Belgium

We investigate n-dimensional(n≥4),conformally flat,minimal,Lagrangian submanifolds of the n-dimensional complex space form in terms of the multiplicities of the eigenvalues of the Schouten tensor and classify those that admit at most one eigenvalue of multiplicity *** the case where the ambient space is Cn,the quasi umbilical case was studied in Blair(2007).However,the classification there is not complete and several examples are ***,we complete(and extend) the classification and we also deal with the case where the ambient complex space form has non-vanishing holomorphic sectional curvature.

关键词： Lagrangian submanifolds conformally flat complex space form warped product submanifold

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Characterization of Totally Geodesic Totally Real 3-dimensional Submanifolds in the 6-sphere

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1557-1564页

作者： Miroslava ANTIC Mirjana DJORIC luc VRANCKEN Faculty of Mathematics University of BelgradeStudentski trg 16 pb. 550 11000 Belgrade Serbia and Montenegro LAMATH ISTV2 Université de Valenciennes Campus du Mont Houy59313 Valenciennes Cedex 9 France

In this paper, we study Lagrangian submanifolds of the nearly Kaehler 6-sphere. We derive a pinching result for the Ricci curvature of such submanifolds thus providing a characterisation of the totally geodesic subman... 详细信息

关键词： Ricci curvature totally real submanifold nearly Kaehler 6-sphere totally geodesic submanifold

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Axial Breakthrough in Ancient Greece. New Considerations： Plato, Confucius, and the Buddha

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Fudan Journal of the Humanities and Social Sciences 2016年第4期9卷 555-564页

作者： luc Brisson Directeur de Recherche Emerite au Centre National de la Recherche Scientifique 4 bis rued'Italie 65013 Paris France

Here I will examine the resemblances and similarities between Plato and two other personages, Confucius and the Buddha, who were his near-contempo- raries, and who enabled a breakthrough. The Platonic break with the world of bodies and the sphere of belief, in favor of a level of intelligible realities, the models of the sensible realities explained by mathematics and moved by the soul, explains the specificity of the Western world, in the field of science, politics, ethics, and even religion.

关键词： Plato Confucius The Buddha Intelligible realities Soul Mathematics - Politics

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Biobased polyurethanes for biomedical applications

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Bioactive Materials 2021年第4期6卷 1083-1106页

作者： Sophie Wendels luc Av´erous BioTeam/ICPEES-ECPM UMR CNRS 7515Universit´e de Strasbourg25 Rue Becquerel67087Strasbourg Cedex 2France

Polyurethanes(PUs)are a major family of polymers displaying a wide spectrum of physico-chemical,mechanical and structural properties for a large range of *** have shown suitable for biomedical applications and are used in this domain since *** current variety of biomass available has extended the diversity of starting materials for the elaboration of new biobased macromolecular architectures,allowing the development of biobased PUs with advanced properties such as controlled biotic and abiotic *** this frame,new tunable biomedical devices have been successfully *** structures with precise tissue biomimicking can be obtained and are adequate for adhesion,proliferation and differentiation of many cell’s ***,new smart shape-memory PUs with adjustable shape-recovery properties have demonstrated promising results for biomedical applications such as wound *** fossil-based starting materials substitution for biomedical implants is slowly improving,nonetheless better renewable contents need to be achieved for most PUs to obtain biobased *** a presentation of some PU generalities and an understanding of a biomaterial structure-biocompatibility relationship,recent developments of biobased PUs for non-implantable devices as well as short-and long-term implants are described in detail in this review and compared to more conventional PU structures.

关键词： Polyurethanes Biobased Biomedical Bioactive Tissue engineering Biocompatibility Scaffold

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