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Evaluation of the etiology and risk factors for maternal sepsis: A single center study in Guangzhou, China

World Journal of Clinical Cases 2021年第26期9卷 7704-7716页

作者： Lin Lin lu-wen ren Xue-Yuan Li wen Sun Yan-Hong Chen Jing-Si Chen Dun-Jin Chen Department of Obstetrics and Gynecology The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510150Guangdong ProvinceChina Key Laboratories for Major Obstetric Diseases of Guangdong Province Guangzhou 510150Guangdong ProvinceChina Department of Fetal Medicine and Prenatal Diagnosis The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510150Guangdong ProvinceChina

BACKGROUND Maternal sepsis is a major cause of gestational morbidity and neonatal mortality worldwide and particularly in *** To evaluate the etiology of maternal sepsis and further identify its risk *** In this retrospective study,we evaluated 70698 obstetric patients who were admitted to the Third Affiliated Hospital of Guangzhou Medical University between January 1,2009 and June 30,*** were divided into sepsis group and non-sepsis group based on the incidence of *** about medical history(surgical and obstetric history)and demographic information were *** Mann-Whitney U test was used to compare patient age,gestational age and duration of hospitalization between the two *** and multivariate logistic regression models were used to analyze the etiology and the risk factors for maternal *** and adjusted odds ratios(OR)are *** A total of 561 of 70698 obstetric patients were diagnosed with infection;of the infected patients,492 had non-sepsis associated infection(87.7%),while 69 had sepsis(12.3%).The morbidity rate of maternal sepsis was 9.76/10000;the fatality rate in the sepsis group was 11.6%(8/69).Emergency admission(OR=2.183)or transfer(OR=2.870),irregular prenatal care(OR=2.953),labor induction(OR=4.665),cervical cerclage(OR=14.214),first trimester(OR=6.806)and second trimester(OR=2.09)were significant risk factors for maternal *** Mode of admission,poor prenatal care,labor induction,cervical cerclage,first trimester and second trimester pregnancy were risk factors for maternal *** coli was the most common causative organism for maternal sepsis,and the uterus was the most common site of infection.

关键词： Maternal sepsis Sepsis-3 Infection Risk factors

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Thermoresponsive helical dendronized poly(arylacetylene)s:modulating the dynamic chirality

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Science China Chemistry 2025年

作者： Xueting lu Lei Wang Liangxuan ren wen Li Afang Zhang International Joint Laboratory of Biomimetic&Smart Polymers School of Materials Science and EngineeringShanghai University

Helical poly(arylacetylene)s have formed an intriguing class of polymers,whose chiralities are dynamic and liable to external *** combining dendronized polymer topology with dendritic oligoethylene glycols (OEGs),we here report on synthesis of a homologous series of thermoresponsive dendronized poly(arylacetylene)s with either poly(phenyl acetylene) or poly(naphthalene acetylene) as the backbones,and investigate tunability of their helical *** polymers carry dendritic OEG pendants with either methoxyl-or ethoxyl-terminals to tune their unprecedent thermoresponsive behaviors,and at the same time,dendritic shielding plays an important role in mediating their thermal phase transition *** of these polymers is originated from the chiral alanine or phenylalanine moieties within the dendritic pendants,which can be tailored through manipulating solvation in different organic solvents or via thermal dehydration and collapse in ***,achiral additives such as linear or dendritic OEGs and benzene derivatives can act similarly as thermal dehydration to induce chirality transitions of these polymers in aqueous phase through interplay competitions between the additives and the polymers against their hydration.

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A Multi-faceted View of the X-Ray Spectral Variability in Seyfert Galaxy Ark 120

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Research in Astronomy and Astrophysics 2025年第1期25卷 228-239页

作者： lu-Xin ren Jun-Xian Wang Jia-Lai Kang CAS Key Laboratory for Research in Galaxies and Cosmology Department of AstronomyUniversity of Science and Technology of China School of Astronomy and Space Science University of Science and Technology of China

Utilizing a range of techniques including multi-band light curves,softness ratio analysis,structure functions,rms spectra,cross-correlation functions,and ratios of spectra from different intervals,we present a comprehensive study of the complex X-ray spectral variability in Seyfert 1 galaxy Ark 120,through re-analyzing its six XMM-Newton observations taken between 2003 and *** find a clear“softer-when-brighter”trend in the 2–10 ke V power-law component over long timescales,with this trend being timescale dependent,as it is much weaker on shorter timescales,similar to that previously detected in NGC ***,a rare“harder-when-brighter”trend is observed during one exposure,indicating dynamic changes in the spectral variability behavior of the power-law *** exceptional exposure,with the spectral variability indeed marked by a power-law pivoting at an unusually low energy of～2 ke V,suggests intricate variations in the thermal Comptonization processes within the ***,when the data below 2 ke V are included,we identify that the soft excess component adds significant complexity to the spectral variability,such as evidenced by a transition from“harder-when-brighter”to“softer-when-brighter”during another single *** extra complexity arises because the variability of the soft excess sometimes follows and sometimes does not follow the changes in the power-law *** findings underscore the necessity of applying multiple analytic techniques to fully capture the multifaceted spectral variability of AGNs.

关键词： galaxies: active galaxies: Seyfert X-rays: galaxies

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Impact of coking plant to heavy metal characteristics in groundwater of surrounding areas:Spatial distribution,source apportionment and risk assessments

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Journal of Environmental Sciences 2025年第3期149卷 688-698页

作者： Congqing Wang Wanjun Wang ChaoWang Shixing ren Yingjun Wu Meicheng wen Guiying Li Taicheng An Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control Guangdong Hong Kong-Macao Joint Laboratory for Contaminants Exposure and HealthInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory Environmental Catalysis and Pollution Control Key Laboratory of City Cluster Environmental Safety and Green developmentSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China

Coking industry is a potential source of heavy metals(HMs)***,its impacts to the groundwater of surrounding residential areas have not been well *** study investigated the pollution characteristics and health risks of HMs in groundwater nearby a typical coking *** HMs including Fe,Zn,Mo,As,Cu,Ni,Cr,Pb and Cd were *** average concentration of total HMswas higher in the nearby area(244.27μg/L)than that of remote area away the coking plant(89.15μg/L).The spatial distribution of pollution indices including heavy metal pollution index(HPI),Nemerow index(NI)and contamination degree(CD),all demonstrated higher values at the nearby residential areas,suggesting coking activity could significantly impact the HMs distribution *** sources of HMs were identified by Positive Matrix Factorization(PMF)model,which indicated coal washing and coking emission were the dominant sources,accounted for 40.4%,and 31.0%,*** ingestionwas found to be the dominant exposure pathway with higher exposure dose to children than *** quotient(HQ)values were below 1.0,suggesting negligible non-carcinogenic health risks,while potential carcinogenic risks were from Pb and Ni with cancer risk(CR)values>10−*** Carlo simulation matched well with the calculated results with HMs concentrations to be the most sensitive *** study provides insights into understanding how the industrial coking activities can impact the HMs pollution characteristics in groundwater,thus facilitating the implement of HMs regulation in coking industries.

关键词： Coking industry Heavy metal Groundwater Spatial distribution Source apportionment Monte Carlo simulation

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Future development research of 5G positioning in 3GPP standards

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The Journal of China Universities of Posts and Telecommunications 2025年

作者： Liu wen ren Hailong Deng Zhongliang School of Electronic Engineering， Beijing University of Posts and Telecommunications

Since the release of the first version of the 5th Generation Mobile Networks (5G) standard， Release-15 (Rel-15)， in June 2018， the 3rd Generation Partnership Project (3GPP) made significant efforts in the field of indoor and outdoor wireless positioning. Notably， Release-16 augmented support for enhanced mobile broadband (eMBB) and ultra-reliable low-latency communication (uRLLC)， particularly within complex indoor settings. To further meet the diverse application needs of positioning scenarios， the 3GPP standards for Release-17 and Release-18 propose new enhancement measures to continuously provide more accurate positioning services. In this paper， the scholarly discourse on 5G positioning was critically examined， providing a systematic review of the 5G positioning standards as delineated in 3GPP's Release-16 and Release-17， and was extended the discussion to the anticipated enhancements in 5G Release-18， along with their underlying motivations. Through these discussions， this article not only a comprehensive perspective on the current development of 5G positioning technology was provided but also was offered forward-looking analysis and predictions for the evolution of positioning technology in the upcoming 3GPP Release-19 phase. Additionally， it serves as a reference for researchers interested in understanding the development of positioning within the standard framework in the field of 5G indoor positioning， which holds significant meaning for promoting research and application of 5G positioning technology.

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Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： Jie Jin Huajing Zhang Qianying lu Linqiang Tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia lu Sijia Tian Yanmei Zhao wenjie ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina Clinical Medical Center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health Central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina School of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review focuses on the use of nanocarrier systems for the efficient and precise delive ry of siRNAs,discussing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can precisely"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic strategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

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A multi-affinity supramolecular nanolayer reinforced PVDF-LLZTO composite polymer electrolyte for stable solid-state lithium batteries

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Nano Research 2025年第2期18卷 317-327页

作者： Changfei Liu Sailong Wang Zhengyi lu Jiaqing Zhao Yuchen Wu Chaojie ren Ruizhi Yang Chao Jin College of Energy Soochow Institute for Energy and Materials InnovationsSoochow UniversitySuzhou 215006China

Technical breakthrough of composite polymer electrolyte(CPE)is one of the key factors that determines the commercial process of the current solid-state lithium ***,high interface impedance limits its electrochemical *** is crucial to optimize the design of multiphase interfaces among different components in CPE for regulating Li+***,a multi-affinity self-assembled 12-crown-4-TFSI(12C4-TFSI)supramolecular nanolayer is introduced into poly(vinylidene difluoride)-Li_(6.75)La_(3)Zr_(1.75)Ta_(0.25)O_(12)(PVDF-LLZTO)CPE as interface *** a result,enhanced Li+conductivity of 4.29×10^(-4)S·cm^(-1),Li+transfer number of 0.44,and stable electrochemical window voltage of 4.8 V ***/Li+at 30℃ are *** symmetric Li||Li cell exhibits an improved critical current density(CCD)of 1.2 mA·cm^(-2) and steady cycling at 0.2 mA·cm^(-2) for over 850 h without visible voltage *** assembled LiǁLiFePO4 coin solid-state cell delivers a high initial discharge capacity of 172.9 mAh·g^(-1) at 0.1 C,rate capability(up to 5.0 C)and outstanding cycling stability with a capacity retention of 87.2% after over 750 cycles at 1.0 *** associated LiǁLiFePO4 pouch cell presents an initial specific discharge capacity of 112.3 mAh·g−1 and successfully runs 30 cycles with a final capacity of 101.8 mAh·g^(-1).This work offers a facile strategy to optimize multiphase interfaces of PVDF-LLZTO CPE for stable solid-state lithium battery.

关键词： solid-state lithium battery composite polymer electrolyte interface impedance modifier supramolecular

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Phenanthrene perturbs hematopoietic development and causes hematopoietic defects in zebrafish

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Journal of Environmental Sciences 2025年第5期151卷 573-581页

作者： Lingyu ren Yue Wang Ying ren Guangke Li Nan Sang College of Environment and Resource Research Center of Environment and HealthShanxi UniversityTaiyuan 030006China

Phenanthrene(Phe)is one of the common polycyclic aromatic hydrocarbons in the environment,and recent studies show that it can cause cardiac developmental toxicity and ***,it is still unknown whether it can affect the hematopoietic development in aquatic *** address this question,zebrafish(Danio rerio)were chronically exposed to Phe at different *** found that Phe caused structural damage to the renal tubules in the kidney,induced malformed erythrocytes in peripheral blood,and decreased the proportion of myeloid cells in adult zebrafish,suggesting possible negative impacts that Phe posed to hematopoietic ***,using in situ hybridization technology,we found that Phe decreased the expression of primitive hematopoietic marker genes,specifically gata1 and pu.1,accompanied by an obstruction of primitive erythrocyte ***,Phe impaired definitive hematopoiesis,increased aberrations of the transient hematopoietic site(PBI),and reduced the generation of hematopoietic stem cells,ultimately influencing the number of erythrocytes and myeloid *** findings suggested that Phe could induce hematopoietic toxicity in zebrafish embryos and pose unknown ecological risks.

关键词： Phenanthrene Zebrafish Hematopoietic development Hematopoietic defect

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Porphyrin-based Covalent Organic Polymers with Bimetallic Active Sites for Boosting Photocatalytic CO_(2) Cycloaddition

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Chemical Research in Chinese Universities 2025年第1期41卷 121-130页

作者： YAN Shengrong ZHANG Lan SHI Songhu ren Yanyan LIU wenhao LI Yujie DUAN Fang lu Shuanglong DU Mingliang CHEN Mingqing Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi214122P.R.China School of Environmental and Biological Engineering Nantong College of Science and TechnologyNantong226007P.R.China Jiangsu Engineering Research Center of Environmental Functional Materials and Pollution Control Nantong226007P.R.China

The photocatalytic CO_(2) cycloaddition to prepare high value-added chemicals,such as cyclic carbonates(CCs)under mild conditions is an effective strategy to realize carbon ***,through a three-step reaction,the porphyrin-based covalent organic polymer with bimetallic active sites(Fe-COP-Zr)is successfully obtained by coordinating Fe^(2+) and Zr^(4+)with porphyrin and bipyridine(Bpy),*** to excellent photosensitivity of porphyrin moieties,Fe-COP-Zr exhibits outstanding visible light absorption,which is very important for the production of photogenerated ***,Fe-COP-Zr shows high photocatalytic performance towards CO_(2) cycloaddition with a yield of 12.1 mmol/h,which is 6 times higher than that of pure covalent organic polymer(COP)and 3 times higher than that of monometallic *** reason for this excellent photocatalytic CO_(2) cycloaddition performance may be ascribed to the synergistic effect of Fe and Zr *** photogenerated electrons are easily injected into epichlorohydrin(ECH)through Fe—O bonds to form affluent electron transition state,and interact with Zr^(4+) as Lewis acid sites for the ring-opening of ECH,which is the rate-determining step for the visible light boosted chemical fixation of CO_(2) into *** work might provide some insights for design and preparation of COPs with multiple active sites to modulate their photocatalytic activities.

关键词： Photocatalytic CO_(2)cycloaddition Cyclic carbonate Covalent organic polymer Bimetallic active site

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小型水电站增加发电量的多种措施

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小水电 2019年第3期 69-73页

作者：卢任文华自科技股份有限公司湖南长沙410205

小型水电站数量众多,如何提高小型水电站的技术水平,改善设备状态,提高发电效率,增加发电量是众多小型水电站业主极为关心的问题。从外部到内部多方面论述了小型水电站增加发电量的措施,取得不错的效果。图8幅。

关键词：小水电站发电量措施效果

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