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TURBULENT MIXING AND EVOluTION IN A STABLY STRATIFIED FLOW WITH A TEMPERATURE STEP

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Journal of Hydrodynamics 2009年第1期21卷 84-92页

作者： QIU Xiang ZHANG Dao-xiang lu Zhi-ming liu Yu-lu Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China Department of Mathematics Shanghai University Shanghai 200444 China

Large-Eddy Simulation （LES） is applied to examine the turbulent mixing and evolution in a stably stratified flow with a thermally sharp interface. Turbulent velocity intensities and turbulent kinetic energy are analyzed by considering the mean shear and stratification effects. The evolution of turbulent mixing layer and turbulent structures are mainly investigated. The results show that the streamwise intensities are much larger than the vertical intensities, and vertical fluctuations decay more rapidly at the presence of stratification. The qualitatively computational results suggest that the mixing layer, defined by the mean temperature, inclines to the side with small inlet velocity. The evolution of the half-width of the mixing layer shows two different slopes. The turbulent structure with high vorticity is restricted in the mixing layer especially in strong stratified cases.

关键词： stratified turbulence turbulent mixing turbulent structure Large-Eddy Simulation (LES)

Simulation of Surface-Induced Morphology Transition and Phase Diagram of Linear Triblock Copolymers under Spherical Confinement

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Chinese Journal of Polymer Science 2023年第1期41卷 166-178页

作者： Ji Wu Shang-Ting Chen Shi-Ben Li lu-ming liu Xiang-Hong Wang Wen-Chang Lang Key Laboratory of Surface modification of Polymer Materials Wenzhou PolytechnicWenzhou325035China Department of Physics Wenzhou UniversityWenzhou325035China Department of Mechanical Engineering Shanghai Technical Institute of Electronics&InformationShanghai201411China

In this work,the nanostructures and phase diagrams of lamella-forming and cylinder-forming ABC linear triblock copolymers confined in spherical cavities are investigated on the basis of real-space self-consistent field *** designate specific monomer-monomer interactions and block composition and study morphology transformation under spherical confinement with a neutral *** potentially valuable morphological structures,such as two-or three-colored spheres,rotational structures,and biconcave disklike structures,are identified in the phase diagrams constructed on confining *** confinement induces an obvious transformation of self-assembled structures,which still retain some of the conformational properties of bulk *** then focus on phase morphology under preferential *** can smooth out differences in block ratios,and similar structures can be assembled from block copolymers with different *** incorporate a non-centrosymmetric feature into our spherical confinement model and design a Janus adsorption field to explore unpredictable microphase *** show that the unbalance of the block ratio causes adsorption to exert a stable shaping effect on *** influence of confinement on the degree of freedom of polymer chains disrupts the influence of adsorption on the complexity and transformation activity of self-assembled *** theoretical results correspond to recent experimental observations and contribute to the field functional material synthesis.

关键词： Triblock copolymer Self-assembly structure Phase transition Three-dimensional confinement Surface adsorption

NUMERICAL SIMULATION OF THE DISPERSION IN OSCILLATING FLOWS WITH REVERSIBLE AND IRREVERSIBLE WALL REACTIONS

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Journal of Hydrodynamics 2009年第4期21卷 482-490页

作者： ZHANG Dao-xiang lu Zhi-ming liu Yu-lu NG Chiu-On Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China College of Mathematics and Computer Science Anhui Normal University Wuhu 241000 China Department of Mechanical Engineering The University of Hong Kong Hong Kong China

This is a study on the mass transport of a solute or contaminant in oscillating flows through a circular tube with a reactive wall layer. The reaction consists of a reversible component due to phase exchange between the flowing fluid and the wall layer, and an irreversible component due to absorption into the wall. The short-time dispersion characteristics are numerically investigated, incorporating the coupling effects between the flow oscillation, sorption kinetics, and retardation due to phase partitioning. The effects of various dimensionless parameters e.g., Da （the Damkoehler number）, α （phase partitioning number）, F （dimensionless absorption number）, and δ （dimensionless Stokes boundary layer number） on dispersion are discussed. In particular, it is found that there exist trinal peaks of the breakthrough curves in some cases.

关键词： dispersion flow oscillation wall reactions

Efficacy of capecitabine and oxaliplatin regimen for extrahepatic metastasis of hepatocellular carcinoma following local treatments

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World Journal of Gastroenterology 2013年第28期19卷 4552-4558页

作者： Sheng-Li He Jie Shen Xian-Jun Sun Xiao-Juan Zhu lu-ming liu Jing-Cheng Dong Department of Hepato-Biliary and Pancreatic Oncology Fudan University Shanghai Cancer Center Department of Integrative Oncology Fudan University Shanghai Cancer Center Department of Integrative Medicine Huashan Hospital Affiliated to Fudan University

AIM: To investigate the efficacy and safety of capecitabine and oxaliplatin (CapeOx) for extrahepatic metastasis after local treatment of hepatocellular carcinoma (HCC). METHODS: Thirty-two patients with extrahepatic metastasis of HCC after local treatment were prospectively enrolled. The CapeOx regimen consisted of capecitabine 1000 mg/m 2 taken orally twice daily on days 1-14, and oxaliplatin was administered at a total dose of 100 mg/m 2 on day 1. The treatment was repeated every 3 wk until disease progression or unaccetablle toxicity. Efficacy and safety were assessable for all enrolled patients. The primary objective of this study was to assess the overall response rate. The secondary objectives were to evaluate the overall survival (OS), the time to tumor progression (TTP) and the toxicity profile of the combined strategy. TTP and OS were assessed by the Kaplan-Meier method and differences between the curves were analyzed using the log-rank test. The statistical software SPSS version 15.0 for Windows (SPSS Inc., Chicago, IL, United States) was used for statistical analysis. All P values were 2-tailed, with statistical significance defined byP ≤ 0.05. RESULTS: Thirty-two patients were assessable for efficacy and toxicity. The median follow-up duration was 15 mo (range, 12-20 mo). At the cut-off date of March 31, 2012, 27 patients died due to tumor progression and one patient died of myocardial infarction. Four patients were still alive (three patients with disease progression). OR was 21.9% (n = 7), the stabilization rate was 40.6% (n = 13), and the disease control rate was 62.5%. The responses lasted from 4 to 19 mo (median, 6 mo). Median TTP was 4.2 mo (95%CI: 2.5-7.4), and the median OS time was 9.2 mo (95%CI: 6.5-17.8). The 1-year survival rate was 43.6% (95%CI: 29.0-66.0). In a multivariate analysis, OS was significantly longer in patients with a Child-Pugh class A compared with class B patients (P = 0.014), with a median OS of 10.1 mo vs 5.4 mo, and there

关键词： Hepatocellular carcinoma Extrahepatic metastasis Capecitabine Oxaliplatin Local treatments

Fluvastatin attenuates myocardial interstitial fibrosis and cardiac dysfunction in diabetic rats by inhibiting over-expression of connective tissue growth factor

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Chinese Medical Journal 2011年第1期124卷 89-94页

作者： DAI Qi-ming lu Jing liu Nai-feng Department of Cardiology Zhongda Hospital Southeast University Nanjing Jiangsu 210009 China

Background Diabetic myocardiopathy is characterized by myocardial interstitial fibrosis and cardiac dysfunction. Statins were found to exert protective effects on cardiovascular disease by suppressing activation of small G proteins, independently of their lipid-lowering effect. The study investigated the effect of fluvastatin on myocardial interstitial fibrosis, cardiac function and mechanism of its action in diabetic rats. Methods Twenty-four male SD rats were randomly assigned to 3 groups： control rats （n=-8）, streptozotocin （STZ）-induced diabetic rats （n=8）, and diabetic rats treated with fluvastatin （administered fluvastatin orally, 10 mg/kg body weight per day, n=-8）. Twelve weeks later, miniature cardiac catheter was inserted into the left ventricle to conduct hemodynamic examination. Then myocardium tissues were collected, collagen content was detected by picro-sirius red staining, real-time quantitative reverse transcription polymerase chain reaction （RT-PCR） was used to detect the mRNA expression of connective tissue growth factor （CTGF）, and Western blotting was used to detect the protein expression of CTGF. Rho activity was determined by pull-down assay. Results After 12 weeks, the left ventricular systolic pressure （LVSP） and maximum rate of left ventricular （LV） pressure rise and fall （＋dP/dt max and -dP/dt max） were significantly lower and left ventricular end diastolic pressure （LVEDP） was higher in the diabetic rats than those in the control rats （P 〈0.01）. Moreover, in LV myocardial tissue of diabetic rats the collagen content, fibronectin, mRNA and protein expression of CTGF and the activity of RhoA were all significantly increased compared with the control rats （P 〈0.01）. Administration of fluvastain obviously improved the cardiac function of diabetic rats, attenuated fibronectin expression, mRNA and protein expression of CTGF and the activity of RhoA in LV myocardium of diabetic rats. Conclusions Fluvastatin attenuates cardiac dysfunction and myo

关键词： HMG-CoA reductase inhibitors diabetes mellitus myocardial fibrosis heart failure Rho/Rho-kinase

Selective removal of sulfamethoxazole by a novel double Z-scheme photocatalyst:Preferential recognition and degradation mechanism

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Environmental Science and Ecotechnology 2024年第1期17卷 163-175页

作者： Jing-Yan Zhang Jie Ding lu-ming liu RuiWu Lan Ding Jun-Qiu Jiang Ji-Wei Pang Yan Li Nan-Qi Ren Shan-Shan Yang State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Harbin Institute of Technology National Engineering Research Center of Water Resources Co. LtdHarbin150090China College of Chemistry Jilin University2699 Qianjin StreetChangchun130012China China Energy Conservation and Environmental Protection Group Beijing100089China School of Environmental Science and Engineering Yancheng Institute of TechnologyYancheng224051China

Sulfamethoxazole(SMX)is a significant environmental concern due to its adverse effects and ecological *** elimination in aquatic environments via photocatalysis presents a viable solution,given its high oxidation ***,such a solution remains controversial,primarily due to a lack of *** we introduce a molecularly imprinted TiO2@Fe_(2)O_(3)@g-C_(3)N_(4)(MFTC)photocatalyst designed for the selective degradation of *** assess MFTC's selectivity,we applied it to degrade synthetic wastewater containing SMX alongside interfering species sulfadiazine(SDZ),ibuprofen(IBU),and bisphenol A(BPA).The results demonstrated a selective degradation efficiency rate of 96.8%,nearly twice that of competing *** molecularly imprinted sites within the catalyst played a crucial role by selectively capturing SMX and enhancing its adsorption,thereby improving catalytic *** degradation process involvedOH and·O_(2)^(-)free radicals,with a newly proposed double Z-scheme mechanism and potential pathway for SMX degradation by the MFTC photocatalytic *** study enriches the application of photocatalysis using molecularly imprinted nanocomposite materials for treating complex pollutant mixtures in water.

关键词： selective photochemical oxidation Molecular imprinting Double Z-scheme heterojunction TiO2@Fe_(2)O_(3)@g-C_(3)N_(4) Sulfamethoxazole degradation

Physiological Mechanism of High and Stable Yield of No-tillage Cast-transplanted Rice

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Agricultural Sciences in China 2002年第4期1卷 404-409页

作者： liu Jun, HUANG Qing, FU Hua, lu Xiu-ming, liu Huai-zhen and LI Kang-huo( Rice Research Institute , Guangdong Academy of Agricultural Sciences , Guangzhou 510640 , P.R. China) Rice Research Institute Guangdong Academy of Agricultural Sciences Guangzhou 510640 P. R . China

Four years' successive comparative experiments showed that no-tillage cast-transplanted rice (NTCTR), compared with conventional tillage cast-transplanted rice (CK), grew slower and produced less tillers at the early growing stage; but, it had shorter ineffective tillering time, less nutrition consumption, stronger individual growth and more uniform growth between individuals and the colony. These characteristics contribute to the increase not only in the productive tiller percentage but also in the ear quality. Furthermore, the flag leaf of NTCTR had higher photosynthetic rate during the filling stage and no early senescence phenomenon at the late stage, which facilitated the accumulation and the transportation of carbohydrates and improved grain setting rate.

关键词： Rice No-tillage cast-transplanted rice(NTCTR) Physiology

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胰腺癌的中医病因病机与辨病论治

中西医结合学报 2008年第12期6卷 1297-1299页

作者：刘鲁明复旦大学肿瘤医院中西医结合科上海200032

1997年秋季，我应邀参加一名59岁女性晚期胰腺癌患者治疗会诊，该患者在浙江大学附属第二医院手术，因肿瘤无法切除而关腹。病理确诊为低分化腺癌，已腹腔内播散。术后1个月患者仍腰背疼痛不止，每晚仅睡3～4h，患者极度悲观。根据中医... 详细信息

1997年秋季，我应邀参加一名59岁女性晚期胰腺癌患者治疗会诊，该患者在浙江大学附属第二医院手术，因肿瘤无法切除而关腹。病理确诊为低分化腺癌，已腹腔内播散。术后1个月患者仍腰背疼痛不止，每晚仅睡3～4h，患者极度悲观。根据中医辨证，采用清胰化积法处方治疗7d后，患者竟然明显好转。由于之后患者病情稳定，故没有给予放、化疗等抗癌疗法，仅以清热化积中药连续用药为主治疗。此后，患者一直病情稳定，生活质量良好。

关键词：中医病机辨病论治胰腺癌

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基于网络丢包的网络视频质量评估

中国图象图形学报 2009年第1期14卷 52-58页

作者：卢刘明陆肖元上海未来宽带技术及应用工程研究中心有限公司上海200336 中国科学院上海微系统与信息技术研究所上海200050

针对传统的视频质量评估模型对于在包交换网络中传输的压缩视频(网络视频)进行质量评估的局限性,如对视频质量进行评估时实时性差、没考虑人眼的视觉感知等问题,提出了一种基于网络丢包的网络视频质量评估模型。该模型采用了统计学理论... 详细信息

针对传统的视频质量评估模型对于在包交换网络中传输的压缩视频(网络视频)进行质量评估的局限性,如对视频质量进行评估时实时性差、没考虑人眼的视觉感知等问题,提出了一种基于网络丢包的网络视频质量评估模型。该模型采用了统计学理论,它可根据视频编码、封装传输的特点,通过可量化的评价指标来评定视频质量受网络丢包的影响程度,以评估网络视频质量。利用该模型进行网络视频质量评估,不仅资源开销小、实时性好,而且特别适合对实时传输的视频流进行视频质量评估。为了验证该模型的正确性与可靠性,采用它与MPQM模型分别对受系列丢包率影响的视频序列进行了评估实验。实验结果表明,该模型的评价结果能较好地吻合MPQM模型的评价结果,且符合人眼的视觉效果。

关键词：网络丢包网络视频视频质量