检索结果-南通市图书馆

Predictive value of angiopoietin-like protein 8 in metabolic dysfunction-associated fatty liver disease and its progression:A case-control study

引用

World Journal of Diabetes 2024年第3期15卷 418-428页

作者： lu-lu gan Can Xia Xuan Zhu Yue Gao Wen-Chang Wu Qi Li Ling Li Zhe Dai Yi-Min Yan Medical College Wuhan University of Science and TechnologyWuhan 430071Hubei ProvinceChina Department of Endocrinology Xiaogan Hospital Affiliated with Wuhan University of Science and TechnologyThe Central Hospital of XiaoganXiaogan 432000Hubei ProvinceChina Department of Endocrinology Zhongnan Hospital of Wuhan UniversityWuhan 430071Hubei ProvinceChina

BACKGROUND The prevalence of metabolic dysfunction-associated fatty liver disease(MAFLD)is rapidly increasing,currently affecting approximately 25%of the global *** fibrosis represents a crucial stage in the development of MAFLD,with advanced liver fibrosis elevating the risks of cirrhosis and hepatocellular *** serum markers are less effective in diagnosing liver fibrosis compared to more complex ***,imaging techniques like transient elastography face limitations in clinical application due to equipment and technical ***,it is imperative to identify a straightforward yet effective method for assessing MAFLD-associated liver *** To investigate the predictive value of angiopoietin-like protein 8(ANGPTL8)in MAFLD and its *** We analyzed 160 patients who underwent abdominal ultrasonography in the Endocrinology Department,Xiaogan Central Hospital affiliated to Wuhan University of Science and Technology,during September 2021-July *** abdominal ultrasonography and MAFLD diagnostic criteria,among the 160 patients,80 patients(50%)were diagnosed with *** MAFLD group was divided into the liver fibrosis group(n=23)and non-liver fibrosis group(n=57)by using a cut-off fibrosis-4 index≥*** regression was used to analyze the risk of MAFLD and the risk factors for its *** operating characteristic curves were used to evaluate the predictive value of serum ANGPTL8 in MAFLD and its *** Compared with non-MAFLD patients,MAFLD patients had higher serum ANGPTL8 and triglyceride-glucose(TyG)index(both P<0.05).Serum ANGPTL8(r=0.576,P<0.001)and TyG index(r=0.473,P<0.001)were positively correlated with *** ANGPTL8 was a risk factor for MAFLD[odds ratio(OR):1.123,95%confidence interval(CI):1.066-1.184,P<0.001).Serum ANGPTL8 and ANGPTL8+TyG index predicted MAFLD[area under the curve(AUC):0.832 and 0.886,respectively;both P<0.05].Compared with MAFL

关键词： Angiopoietin-like protein 8 Metabolic dysfunction-associated fatty liver disease Fibrosis-4 index Liver fibrosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CNN-LSTM based incremental attention mechanism enabled phase-space reconstruction for chaotic time series prediction

引用

Journal of Electronic Science and Technology 2024年第2期22卷 77-90页

作者： Xiao-Qian lu Jun Tian Qiang Liao Zheng-Wu Xu lu gan Bidding and Purchasing Center University of Electronic Science and Technology of ChinaChengdu611731China Yibin Research Institute University of Electronic Science and Technology of ChinaYibin644000China School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu611731China

To improve the prediction accuracy of chaotic time series and reconstruct a more reasonable phase space structure of the prediction network,we propose a convolutional neural network-long short-term memory(CNN-LSTM)prediction model based on the incremental attention ***,a traversal search is conducted through the traversal layer for finite parameters in the phase ***,an incremental attention layer is utilized for parameter judgment based on the dimension weight criteria(DWC).The phase space parameters that best meet DWC are selected and fed into the input ***,the constructed CNN-LSTM network extracts spatio-temporal features and provides the final prediction *** model is verified using Logistic,Lorenz,and sunspot chaotic time series,and the performance is compared from the two dimensions of prediction accuracy and network phase space ***,the CNN-LSTM network based on incremental attention is compared with long short-term memory(LSTM),convolutional neural network(CNN),recurrent neural network(RNN),and support vector regression(SVR)for prediction *** experiment results indicate that the proposed composite network model possesses enhanced capability in extracting temporal features and achieves higher prediction ***,the algorithm to estimate the phase space parameter is compared with the traditional CAO,false nearest neighbor,and C-C,three typical methods for determining the chaotic phase space *** experiments reveal that the phase space parameter estimation algorithm based on the incremental attention mechanism is superior in prediction accuracy compared with the traditional phase space reconstruction method in five networks,including CNN-LSTM,LSTM,CNN,RNN,and SVR.

关键词： Chaotic time series Incremental attention mechanism Phase-space reconstruction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Resolving aging dynamics of a 3D colloidal glass

引用

Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 110-118页

作者： XiaoJuan Wang Jun Duan gan Ding YunZhuo lu Xing lu LanHong Dai MinQiang Jiang State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Materials Science and Engineering Dalian Jiaotong UniversityDalian 116028China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Physical aging is an inherent property of glassy matter, but understanding its microscopic mechanism remains a challenge particularly at the particle level. In this work, we use a confocal microscope to in-situ trace the particle trajectories in a 3D colloidal glass for 73000 s, aiming at resolving the aging dynamics. By calculating the mean square displacement of particle motions, we find that the glass aging with time can be divided into three stages: β relaxation, α relaxation and free diffusion. The system's mean square displacement at each aging state is quantitatively resolved into three contributions of particle dynamics modes: vibration within the nearest-neighbor cages, hopping between cages and cooperative rearrangement. We further calculate the particle's free volume and find that the β-to-α transition is accompanied by the temporary increase of the system-averaged free volume due to pronounced hops of particles. Nevertheless, the temporal autocorrelation of the free volume spatial distribution still obeys a monotonically stretched exponential decay with an exponent of 0.76, which is related to the sub-diffusion dynamics of cooperative rearrangements and hops mixed in α relaxation. According to the resolved vibrational displacements,we calculate the vibrational density of states of this 3D glass, and the characteristic boson peak is reproduced at low *** findings shed insight into the particle-level aging dynamics of a real glass under purely thermal activation.

关键词： colloidal glass physical aging particle dynamics free volume boson peak

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Capturing and visualizing the phase transition mediated thermal stress of thermal barrier coating materials via a cross-scale integrated computational approach

引用

Journal of Advanced Ceramics 2024年第4期13卷 413-428页

作者： Mengdi gan Tianlong lu Wei Yu Jing Feng Xiaoyu Chong Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China

The generation and evaluation of severely high thermal stress(σ)is known to be responsible for failure of thermal barrier coatings(TBCs)during thermal *** is crucial and challenging to capture fluctuations inσcaused by the phase transition,which has motivated us to develop a high-throughput multiscale evaluation method forσin TBCs that considers the phase transition of the top ceramic materials by coupling first-principles calculations with finite element *** method quantitatively evaluates and visualizesσof the real TBC structure under thermal cycling by multifield ***,the thermophysical properties calculated by the first-principles calculations consider the effects of temperature and phase transition,which not only reduces the cost of obtaining data but also has a more physical *** this work,rare earth tantalites(RETaO_(4))are introduced as ceramic layers,and the results demonstrate thatσundergoes a rapid escalation near the phase transition temperature(T_(t)),particularly in the TBCs_GdTaO_(4) system,where it rises from 224 to 435 *** discontinuity inσmay originate from the significant alterations in Young’s modulus(increase by 27%–78%)and thermal conductivity(increase by 53%–146%)near T_(t).The TBCs_NdTaO_(4) and TBCs_SmTaO_(4) systems exhibit noteworthy temperature drop gradients and minimalσfluctuations,which are beneficial for extending service lifetime of *** approach facilitates the prediction of failure mechanisms and provides theoretical guidance for the reverse design of TBC materials to obtain low thermal stress systems.

关键词： thermal conductivity first-principles calculations thermodynamics thermal stress thermophysical properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel method for the green utilization of waste fried oil

引用

Particuology 2024年第1期84卷 1-11页

作者： gan Cheng Mengni Zhang Yang lu Yanhui Zhang Bin Lin Ee Von Lau College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo454003China Henan Key Laboratory for Green and Efficient Mining&Comprehensive Utilization of Mineral Resources Henan Polytechnic UniversityJiaozuo454003China Collaborative Innovation Center of Coal Work Safety and Clean High Efficiency Utilization Henan Polytechnic UniversityJiaozuo454003China School of Engineering Monash University MalaysiaSubang JayaSelangor47500Malaysia

Waste fried oil was studied to prepare three different types of detergent such as soap,liquid soap and soap powder via saponification *** preparation conditions of soap base were optimized by orthogonal *** specific preparation processes included waste fried oil treatment,orange peel extract preparation,saponification,demoulding and *** showed that the optimal con-ditions for saponification were as follows:ratio of pure waste fried oil to coconut oil=6∶4,alkali liquor(NaOH)mass fraction 30%,saponification temperature 70℃,orange peel extract concentration 15%.The mature soap was then used to make liquid soap and soap powder by surfactant(sodium dodecylbenzene sulfonate,coconut diethanol amide)addition,followed by *** prepared detergent conforms to the production standard of strong decontamination ability,possesses stable performance,is gentle to skin and non-toxic.

关键词： Waste fried oil Detergent Saponification Decolorization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Eco-physiological characteristics of Tetracentron sinense *** in response to different light intensities

引用

Journal of Forestry Research 2024年第3期35卷 29-44页

作者： Rong Wang Xueheng lu Hongyan Han Xuemei Zhang Yonghong Ma Qinsong Liu Xiaohong gan Key Laboratoryof Southwest Wildlife Resources Conservation Ministry of EducationChina West Normal UniversityNanchong 637009People's Republic of China Institute of Plant Adaptation and Utilization in Southwest Mountain China West Normal UniversityNanchong 637009People's Republic of China Office of the People's Government of Yuexi County Yuexi County 616650Liangshan Yi Autonomous PrefecturePeople's Republic of China

The regeneration of Tetracentron sinense *** poor in the understory and in open areas due to the charac-teristics of natural regeneration of the species on forest edges and in *** is unclear whether different light intensities in various habitats affect eco-physiological characteristics of saplings and their natural *** this study,the light intensity in *** habitats was simulated by artificial shading(L1:100%NS(natural sunlight)in the open;L2:50%NS in a forest gap or edge;L3:10%NS in understory)to investigate differences in morphology,leaf structure,physiology,and photosynthesis of 2-year-old sap-lings,and to analyze the mechanism of light intensity on sapling *** differences were observed in morphology(including leaf area,and specific leaf area)under different light *** to L1 and L3,chloroplast structure in L2 was *** increasing time,superoxide dismutase(SOD)and catalase(CAT)activities in L2 became gradually higher than under the other light intensities,while malondialdehyde(MDA)content was *** decreased osmoregulation substance contents of leaves but increased *** results suggest that light intensities significantly affect the eco-physiological characteristics of *** saplings and they would respond most favorably at intermediate levels of light by optimizing eco-physiological ***,50%natural sunlight should be created to promote saplings establishment and population recovery of *** during in situ conservation,including sowing mature seeds in forest edges or gaps and providing appropriate shade protection for seedlings and saplings in the open.

关键词： Chloroplast ultrastructure Eco-physiological characteristics Light intensities Sapling establishment Tetracentron sinense Oliv

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lignocellulose-Based Optical Biofilter with High Near-Infrared Transmittance via Lignin Capturing–Fusing Approach

引用

Research 2024年第3期2023卷 139-149页

作者： Shixu Yu Yifang Zhou Meixue gan lu Chen Yimin Xie Yuning Zhong Qinghua Feng Chaoji Chen Hubei Provincial Key Laboratory of Green Materials for Light Industry Hubei University of TechnologyWuhan 430068China.Hubei Biomass-Resource Chemistry and Environmental Biotechnology Key LaboratorySchool of Resource and Environmental SciencesWuhan UniversityWuhan 430079China Hubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory School of Resource and Environmental SciencesWuhan UniversityWuhan 430079China Hubei Open University Wuhan 430074China.

Near-infrared (NIR) transparent optical filters show great promise in night vision and receiving windows. However, NIR optical filters are generally prepared by laborious, environmentally unfriendly processes that involve metal oxides or petroleum-based polymers. We propose a lignin capturing–fusing approach to manufacturing optical biofilters based on molecular collaboration between lignin and cellulose from waste agricultural biomass. In this process, lignin is captured via self-assembly in a cellulose network;then, the lignin is fused to fill gaps and hold the cellulose fibers tightly. The resulting optical biofilter featured a dense structure and smooth surface with NIR transmittance of ~90%, ultralow haze of close to 0%, strong ultraviolet-visible light blocking (~100% at 400 nm and 57.58% to 98.59% at 550 nm). Further, the optical biofilter has comprehensive stability, including water stability, solvent stability, thermal stability, and environmental stability. Because of its unique properties, the optical biofilter demonstrates potential applications in the NIR region, such as an NIR-transmitting window, NIR night vision, and privacy protection. These applications represent a promising route to produce NIR transparent optical filters starting from lignocellulose biomass waste.

关键词： transparent starting waste

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research of simulation and experiment on arc characteristics of gas mechanical switch

引用

HIGH VOLTAGE 2024年第3期9卷 626-635页

作者： Jiang, Cheng Qu, lu Yu, Zhangqing gan, Zhizheng Yan, Xin Zeng, Rong Huang, Yulong Li, Shaofu Tsinghua Univ Dept Elect Engn Beijing Peoples R China Southwest Univ Sci & Technol Sch Informat Engn Mianyang Peoples R China Tsinghua Univ Sichuan Energy Internet Res Inst Chengdu Peoples R China

An arc is the high-temperature discharge plasma produced in the opening process of mechanical switches, which directly affects the breaking capability of a hybrid DC circuit breaker. According to the physical mechanism of an electric arc, the construction of an arc model for simulation analysis is an important technical means in the electrical field. In this study, based on the theory of magneto hydrodynamics (MHD), a gas mechanical switch model of a natural commutation DC circuit breaker with a compound gap is established. The arc motion process under different conditions is simulated and calculated. The influence of different initial pressures, different opening speeds, and different striking currents on the arc voltage characteristics is analysed. The results show that the larger the gas pressure, the smaller the arc volume and the higher the arc voltage. The faster the opening speed, the longer the arc and the higher the arc voltage; with the increase of the current, the arc voltage increases rapidly at a low current, while the arc voltage increases slowly at a high current.

关键词： CIRCUIT-BREAKER COEFFICIENTS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

引用

Signal Transduction and Targeted Therapy 2024年第8期9卷 3176-3241页

作者： Pelin lu Dongxue Ruan Meiqi Huang Mi Tian Kangshun Zhu Ziqi gan Zecong Xiao Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630PR China Department of Minimally Invasive Interventional Radiology and Laboratory of Interventional RadiologyThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260PR China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseNational Center for Respiratory MedicineDepartment of Respiratory and Critical Care MedicineGuangzhou Institute for Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120PR China Department of Stomatology Chengdu Second People's HospitalChengdu 610021PR China Hospital of Stomatology Guangdong Provincial Key Laboratory of StomatologyGuanghua School of StomatologySun Yat-sen UniversityGuangzhou 510055PR China

The applications of hydrogels have expanded significantly due to their versatile,highly tunable properties and breakthroughs in biomaterial *** this review,we cover the major achievements and the potential of hydrogels in therapeutic applications,focusing primarily on two areas:emerging cell-based therapies and promising non-cell therapeutic *** the context of cell therapy,we discuss the capacity of hydrogels to overcome the existing translational challenges faced by mainstream cell therapy paradigms,provide a detailed discussion on the advantages and principal design considerations of hydrogels for boosting the efficacy of cell therapy,as well as list specific examples of their applications in different disease *** then explore the potential of hydrogels in drug delivery,physical intervention therapies,and other non-cell therapeutic areas(e.g.,bioadhesives,artificial tissues,and biosensors),emphasizing their utility beyond mere delivery ***,we complement our discussion on the latest progress and challenges in the clinical application of hydrogels and outline future research directions,particularly in terms of integration with advanced biomanufacturing *** review aims to present a comprehensive view and critical insights into the design and selection of hydrogels for both cell therapy and noncell therapies,tailored to meet the therapeutic requirements of diverse diseases and situations.

关键词： directions overcome breakthrough

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microstructure development of Ti scaffold by laser powder bed fusion with chemical polishing and its mechanical properties, biocompatibility

引用

BIOSURFACE AND BIOTRIBOLOGY 2024年第2期10卷 52-62页

作者： lu, Changfu Chen, Jing Ma, Teng Chen, Yuxin Zeng, Da gan, Yiliang Yang, Youwen Double Med Technol Inc Xiamen Peoples R China Jiangxi Univ Sci & Technol Inst Addit Mfg Nanchang Peoples R China Tongling Univ Key Lab Construct Hydraul Robots Anhui Higher Educ Tongling Peoples R China Nanjing Univ Coll Engn & Appl Sci Nanjing Peoples R China

Titanium (Ti) dental scaffolds are widely used in dental prosthetics due to their excellent mechanical properties and biocompatibility. However, conventional Ti scaffolds manufactured through machining often do not fit perfectly with the bone defect site. Laser powder bed fusion (LPBF) technology enables the personalised manufacturing of custom-made Ti scaffolds. A custom-made Ti scaffold was prepared using LPBF and its surface roughness was improved through chemical polishing. To enhance the surface roughness, a nitric acid mixed solution with a specific composition of HF: HNO3:C3H6O3 = 2:2:3 was used. The polishing mechanism was investigated by adjusting the F/Ti ratio to control the formation and dissolution of the oxide film. As a result, the surface of the Ti scaffold after polishing exhibited a smooth and flat appearance compared to the LPBF part, with a reduced surface roughness (Ra) of 1.23 +/- 0.19 mu m. The custom-made Ti scaffold also demonstrated favourable mechanical properties, with a bending strength of 335.18 +/- 33.62 MPa and stiffness of 2.13 +/- 0.21 GPa. Furthermore, in vitro cell tests confirmed the excellent biocompatibility of the custom-made Ti scaffold. The authors present a feasible strategy for the further clinical application of custom-made Ti scaffolds, offering enhanced surface properties and addressing the limitations of conventional machining methods.

关键词： additive manufacturing dental material property surface roughness GUIDED BONE REGENERATION ALLOY OPTIMIZATION PARAMETERS MEMBRANE BEHAVIOR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：