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[Effect of acupuncture-moxibustion on idiopathic facial palsy at acute phase in the real world: a cohort study]

Zhongguo zhen jiu = Chinese acupuncture & moxibustion 2025年第2期45卷 133-8页

作者： Linyan Hu Jianhua sun Lixia Pei lu Chen Department of Acupuncture and Rehabilitation Affiliated Hospital of Nanjing University of Chinese Medicine Jiangsu Provincial Hospital of TCM Nanjing 210029 China.

OBJECTIVE:To compare the effect of acupuncture-moxibustion on idiopathic facial palsy (IFP) at acute phase and recovery phase.METHODS:According to whether received acupuncture-moxibustion at acute phase or not, 198 IFP patients were divided into an early-phase intervention group (118 cases) and a non-early-phase intervention group (80 cases). With the propensity score matching employed, 70 cases were included in each group. On the basis of the conventional treatment of western medicine, acupuncture-moxibustion was supplemented in the two groups. In the early-phase intervention group, acupuncture-moxibustion was delivered at the acute phase (duration of illness≤7 days); in the non-early-phase intervention group, acupuncture-moxibustion was operated at the recovery phase (duration of illness>7 days). At the acute phase, warm needling was performed at Yifeng (TE17), Xiaguan (ST7), Hegu (LI4) and Zusanli (ST36) on the affected side; and at the recovery phase, electroacupuncture was delivered at Cuanzhu (BL2), Sizhukong (TE23) and Yangbai (GB14), etc. on the affected side, with the disperse-dense wave and 2 Hz/100 Hz of frequency. The intervention was operated for 30 min each time, once every two days, three treatments weekly and for 4 weeks. Before treatment, 1 week and 4 weeks of treatment, the House-Brackmann (H-B) facial nerve function grade, the score of sunnybrook facial nerve function, and the score of facial disability index (FDI) were compared between the two groups. The clinical effect in 1 and 4 weeks of treatment and safety were evaluated.RESULTS:In 1 and 4 weeks of treatment, the H-B grade was improved when compared with that before treatment in each group (sunnybrook scores and the scores of physical function of FDI were elevated in comparison with those before treatment

关键词： acupuncture-moxibustion idiopathic facial nerve palsy, acute phase opportunity of intervention propensity score matching real-world study

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Rising frequency of ozone-favorable synoptic weather patterns contributes to 2015-2022 ozone increase in Guangzhou

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Journal of Environmental Sciences 2025年第2期148卷 502-514页

作者： Nanxi Liu Guowen He Haolin Wang Cheng He Haofan Wang Chenxi Liu Yiming Wang Haichao Wang Lei Li Xiao lu Shaojia Fan School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Guangdong Provincial Observation and Research Station for Climate Environment and Air Quality Change in the Pearl River Estuary Key Laboratory of Tropical Atmosphere-Ocean System(Sun Yat-sen University)Ministry of EducationZhuhai 519082China

Objective weather classification methods have been extensively applied to identify dominant ozone-favorable synoptic weather patterns(SWPs),however,the consistency of different classification methods is rarely *** this study,we apply two widely-used objective methods,the self-organizing map(SOM)and K-means clustering analysis,to derive ozone-favorable SWPs at four Chinese megacities in *** find that the two algorithms are largely consistent in recognizing dominant ozone-favorable SWPs for four Chinese *** the case of classifying six SWPs,the derived circulation fields are highly similar with a spatial correlation of 0.99 between the two methods,and the difference in themean frequency of each SWP is less than 7%.The six dominant ozone-favorable SWPs in Guangzhou are all characterized by anomaly higher radiation and temperature,lower cloud cover,relative humidity,and wind speed,and stronger subsidence compared to climatology *** find that during 2015-2022,the occurrence of ozone-favorable SWPs days increases significantly at a rate of 3.2 days/year,faster than the increases in the ozone exceedance days(3.0 days/year).The interannual variability between the occurrence of ozone-favorable SWPs and ozone exceedance days are generally consistent with a temporal correlation coefficient of *** particular,the significant increase in ozone-favorable SWPs in 2022,especially the Subtropical High type which typically occurs in September,is consistent with a long-lasting ozone pollution episode in Guangzhou during September *** results thus reveal that enhanced frequency of ozone-favorable SWPs plays an important role in the observed 2015-2022 ozone increase in Guangzhou.

关键词： Ozone(O3) Objective weather classification methods Synoptic weather patterns Trends Guangzhou

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樟树叶提取物对木材霉菌的防治效果及防霉机理研究

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北京林业大学学报 2017年第1期39卷 99-106页

作者：常璐璐孙墨珑徐国祺刘泽旭王立海东北林业大学工程技术学院东北林业大学理学院

为探明樟树叶提取物对木材霉菌的防治效果及防霉机理,采用牛津杯法,探讨了不同质量分数的提取物对3种木材常见霉菌(桔青霉、绿木霉、黑曲霉)的抑菌性,之后通过光学显微镜和分光光度法对防霉机理进行分析,探讨了其在木材中的霉菌防治效... 详细信息

为探明樟树叶提取物对木材霉菌的防治效果及防霉机理,采用牛津杯法,探讨了不同质量分数的提取物对3种木材常见霉菌(桔青霉、绿木霉、黑曲霉)的抑菌性,之后通过光学显微镜和分光光度法对防霉机理进行分析,探讨了其在木材中的霉菌防治效果。结果表明:樟树叶提取物对桔青霉、绿木霉以及黑曲霉均有一定的抑制作用,且其通过破坏霉菌菌丝结构,扰乱霉菌生长周期,从而抑制3种霉菌生长。质量分数为12.50%的提取物对3种霉菌的抑菌效果最佳,对应的抑菌圈直径分别为:桔青霉14.2 mm,绿木霉14.9 mm,黑曲霉20.1 mm。提取物对3种霉菌的最低抑菌质量分数为:桔青霉0.50%~1.00%,绿木霉0.50%~1.00%,黑曲霉0.25%。对不同菌种,分别采用如下处理方式可使平均感染值达到最小,防治效力达到最大:桔青霉(涂刷处理)、绿木霉以及混合菌(浸渍处理)、黑曲霉(任意一种处理方式均可),其中浸渍处理方式适用霉菌最为广泛。

关键词：樟树叶提取物木材防霉作用机理

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The Finite Element Analysis of Optimal Orthodontic Force for Canine Distalization with Long-Arm Brackets

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Journal of Biosciences and Medicines 2025年第1期13卷 196-205页

作者： Zhidan Zhu Xiaojing sun Bin lu Qijie Shi Yun Tang Siyu Zou Qian Jiang School of Stomatology Guilin Medical University Guilin China Department of Orthodontics Guilin Stomatological Hospital Guilin China School of Mechanical and Electrical Engineering Guilin University of Electronic Technology Guilin China Department of Orthodontics Affiliated Stomatological Hospital of Guilin Medical University Guilin China

Objective: To compare the stress distribution in the periodontal ligament under different orthodontic forces during canine distalization using long-arm brackets, and to determine the optimal force value for this device in orthodontic treatment. Methods: A finite element model was constructed after extracting the mandibular first premolar, and a long-arm bracket with a traction height of 6 mm was placed on the labial side of the mandibular canine. Three working conditions of 50 g, 100 g, and 150 g were simulated, and the magnitude and distribution of von Mises stress in the periodontal ligament were compared for each condition. Results: The maximum von Mises stress in the periodontal ligament was 0.013281 MPa in the 50 g condition, 0.02536 MPa in the 100 g condition, and 0.035549 MPa in the 150 g condition. As the orthodontic force increased, the stress distribution area in the periodontal ligament also expanded. Conclusion: A 100 g orthodontic force is the most suitable when using long-arm brackets, providing a relatively uniform stress distribution in the periodontal ligament and keeping the stress within a reasonable range.

关键词： Orthodontic Force Tooth Movement Finite Element Analysis Periodontal Ligament Stress

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U(Ⅵ)在偕胺肟基功能化介孔二氧化硅上的吸附

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核化学与放射化学 2018年第3期40卷 166-174页

作者：李博林朱璐王路生孙亚楼杨柳陈愫文兰州大学核科学与技术学院甘肃兰州730000

通过嫁接法合成了偕胺肟基功能化修饰的介孔二氧化硅SBA-15-AO和SBA-15-2AO,采用傅里叶红外谱图(FTIR)、X射线粉末衍射(XRD)、透射电镜(TEM)、比表面分析(BET)和元素分析等手段对所合成的样品进行了表征;采用批式法对比研究了U(Ⅵ)在未... 详细信息

通过嫁接法合成了偕胺肟基功能化修饰的介孔二氧化硅SBA-15-AO和SBA-15-2AO,采用傅里叶红外谱图(FTIR)、X射线粉末衍射(XRD)、透射电镜(TEM)、比表面分析(BET)和元素分析等手段对所合成的样品进行了表征;采用批式法对比研究了U(Ⅵ)在未功能化的SBA-15和偕胺肟功能基含量不同的样品SBA-15-AO和SBA-15-2AO上的吸附行为。结果表明:偕胺肟基的引入未破坏SBA-15的孔结构,其比表面积和孔体积有所减小,但对U(Ⅵ)的吸附能力显著增强;室温下,偕胺肟基团含量较大的SBA-15-2AO对U(Ⅵ)的吸附能力最大,其最大吸附容量约为0.885mmol/g,是未功能化的SBA-15最大吸附容量的4倍;U(Ⅵ)在SBA-15、SBA-15-AO和SBA-15-2AO上的吸附均较迅速,180 min达到吸附平衡,均符合准二级吸附动力学模型;吸附过程受pH影响显著,但离子强度对吸附的影响较小,吸附为放热过程;在一系列干扰离子存在下,偕胺肟基功能化的SBA-15对U(Ⅵ)具有良好的吸附选择性。

关键词：介孔二氧化硅 U(Ⅵ) 偕胺肟基吸附

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Evaluation of paddy soil quality in Wanchang area of Jilin City

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Global Geology 2025年第1期28卷 70-78页

作者： LI Chao lu Jilong WEI Qiaoqiao HOU Yaru ZHAO Wei HUA Zhaofu sun Xiaohan College of Geoexploration Science and Technology Jilin UniversityChangchun 130026China

In order to identify the nutrient level and environmental quality of paddy fields in Wanchang area,and to provide scientific basis and technical support for planting rice in Wanchang area, the soil geochemicalsurvey was carried out, 30 samples were collected from paddy soil in Wanchang area, and 20 elements(indicators) were analyzed. The characterization of the elemental content of soils in the study area was carriedout, and the geochemical level for soil nutrients, the geochemical level for the soil environment, and thecomprehensive geochemical level of soil quality were evaluated. The results showed that the average valuesof K content and pH of the soil in the study area were smaller than the background values of Jilin Province,and the average values of 18 elements including N, P, Ca, S, Pb, Zn etc. were bigger than the backgroundvalues of Jilin Province. The results of the evaluation of soil single element nutrient in the study area showedthat the available state nutrient levels of Mn, Zn, Cu, and K increased compared with the total amounts ofnutrients level, with Cu increasing the most;the available state nutrient level of N, P, B, and Mo decreasedcompared with the total amounts of nutrients level, with Mo decreasing the most. The comprehensive levelof soil nutrients geochemistry in paddy fields was mainly Level III (medium), accounting for 53.33%, andthe low abundance level was caused by the lack of P element;the comprehensive level of soil environmentalgeochemistry was mainly Level I (clean), accounting for 96.67%, with only slight pollution caused byCd. The comprehensive geochemical level of soil quality was mainly Level II, accounting for 66.67%.Suggestions were put forward for the rational utilization of soil resources in paddy fields in the study area.

关键词： paddy soil nutrients environmental evaluation soil quality evaluation Wanchang area Jilin City

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei Zhang Yubao lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming Zhang Bin Liu Limin Rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

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产-需全链条耦合的矿山综合能源电-热-煤协同低碳调度

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电力自动化设备 2025年第2期45卷 61-68页

作者：吕超贤罗刚孙文梁睿张鸽中国矿业大学电气工程学院江苏徐州221116 国网冀北电力有限公司唐山供电公司河北唐山063000

矿山产-需环节耦合紧密,如何实现多环节的协同优化以提升系统的用能经济性与减碳效益是亟待解决的问题。为此,提出产-需全链条耦合的矿山综合能源系统(CMIES)电-热-煤协同经济低碳优化调度方法。从矿山生产工艺流程出发,分析各环节之间... 详细信息

矿山产-需环节耦合紧密,如何实现多环节的协同优化以提升系统的用能经济性与减碳效益是亟待解决的问题。为此,提出产-需全链条耦合的矿山综合能源系统(CMIES)电-热-煤协同经济低碳优化调度方法。从矿山生产工艺流程出发,分析各环节之间的耦合特征,构建含煤矿生产-用能多环节的CMIES电-热-煤耦合拓扑;剖析矿山安全开采前提下的煤流工序、伴生能源产出和利用方式,刻画运煤、排水环节的柔性特征,建立多环节运行模型;以矿山用能成本与碳排放惩罚成本最小为目标,构建电-热-煤协同的CMIES经济低碳调度模型。以山西省某煤矿为算例进行仿真,验证所提模型与方法的有效性。仿真结果表明,所提模型与方法通过工序调整、环节优化有效降低了矿山的用能成本及碳排放量,实现了多环节协同下的CMIES经济低碳运行。

关键词：矿山综合能源系统煤流伴生能源电-热-煤协同低碳调度

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TiO_(2)-WS_(2)异质结的制备及其在医药废水处理中的应用

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化学研究与应用 2025年第1期37卷 128-136页

作者：孙龙仁张璐平顶山工业职业技术学院河南平顶山467000

通过水热法原位合成了TiO_(2)-WS_(2)异质结样品,采用XRD、Raman、XPS、SEM、TEM、HR-TEM、BET、UVVis DRS、PL和EIS技术对样品的结构组成和光电性质进行分析,以环丙沙星为目标污染物,对样品的光降解性能进行评价。研究结果表明:TiO_(2)... 详细信息

通过水热法原位合成了TiO_(2)-WS_(2)异质结样品,采用XRD、Raman、XPS、SEM、TEM、HR-TEM、BET、UVVis DRS、PL和EIS技术对样品的结构组成和光电性质进行分析,以环丙沙星为目标污染物,对样品的光降解性能进行评价。研究结果表明:TiO_(2)-WS_(2)异质结样品能够提高光生载流子的分离效率,使得TiO_(2)-WS_(2)样品在光催化降解环丙沙星时展现出了优异的活性,经过120 min光照后,对环丙沙星的达到了94.8%,较TiO_(2)样品和WS_(2)样品降解率明显提高,自由基捕获实验表明·OH和·O_(2)-为TiO_(2)-WS_(2)样品光催化降解环丙沙星过程中的主要活性物种。

关键词： TiO_(2)-WS_(2) 环丙沙星光催化降解率

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Purinergic signaling by TCRaβ~+double-negative T regulatory cells ameliorates liver ischemia–reperfusion injury

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Science Bulletin 2025年第2期70卷 241-254页

作者： Hua Jin Mingyang Li Xiyu Wang lu Yang Xinjie Zhong Zihan Zhang Xiaotong Han Jingjing Zhu Mengyi Li Songlin Wang Simon C.Robson Guangyong sun Dong Zhang Immunology Research Center for Oral and Systemic Health Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Medical Research Center Beijing Institute of Respiratory Medicine and Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China Department of Gastroenterology Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China General Surgery Department Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Beijing Laboratory of Oral Health Capital Medical University School of Basic MedicineBeijing 100069China Center for Inflammation Research Department of AnesthesiaCritical Care&Pain Medicineand Department of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02115USA

Hepatic ischemia–reperfusion injury(HIRI)is an important cause of liver injury following liver transplantation and major resections,and neutrophils are the key effector cells in ***-negative T regulatory cells(DNT)are increasingly recognized as having critical regulatory functions in the immune *** DNT expresses distinct immunoregulatory mechanisms to modulate neutrophils,as in HIRI,remains largely *** this study,we found that murine and human DNT highly expressed CD39that protected DNT from extracellular ATP-induced apoptosis and generated adenosine in tandem with CD73,to induce high levels of neutrophil ***,extracellular adenosine enhanced DNT survival and suppressive function by upregulating survivin and NKG2D expression via the A2AR/pAKT/FOXO1 signaling *** transfer of DNT ameliorated HIRI in mice through the inhibition of neutrophils in a CD39-dependent ***,the adoptive transfer of A2ar^(-/-)DNT validated the importance of adenosine/A2AR signaling,in promoting DNT survival and immunomodulatory function to protect against HIRI in *** conclusion,purinergic signaling is crucial for DNT homeostasis in *** of CD39 or activation of A2AR signaling in DNT may provide novel therapeutic strategies to target innate immune disorders.?2024 The *** by Elsevier *** behalf of Science China *** is an open accessarticle under the CC BY-NC-ND license(http://***/licenses/by-nc-nd/4.0/).

关键词： Double-negative T regulatory cells Hepatic ischemia and reperfusion injury CD39 Adenosine A2AR

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