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Separation of cortical arteries and veins in optical neurovascular imaging

Journal of Innovative Optical Health Sciences 2014年第3期7卷 22-30页

作者： Linna Zhao Yao Li hongyang lu lu Yuan Shanbao Tong Med-X Research Institute Shanghai Jiao Tong University1954 Huashan Rd.Shanghai 200030P.R.China School of Biomedical Engineering Shanghai Jiao Tong University800 Dongchuan Rd. Shanghai 200240P.R.China School of Life Science and TechnologyHuazhong University of Science and Technology 1037 luoyu Rd. Wuhan 430074P.R.China

Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics,such as the changes of cerebral blood flow,perfusion or oxygen con-centration in arteries and veins under different pathological and physiological *** the cerebral vessel segmentation and vessel-type separation are challenging due to the complexity of cortical vessel characteristics and low spatial signal-to-noise *** this work,we presented an effective full-field method to differentiate arteries and veins in cerebral cortex using dual-modal optical imaging technology including laser speckle imaging(LSI)and optical intrinsic signals(OIS)*** raw contrast images were acquired by LSI and processed with enhanced laser speckle contrast analysis(eLASCA),*** vascular pattern was extracted and seg-mented using region growing algorithm from the eLASCA-based ***,OIS imageswere acquired altermatively with 630 and 870 nm to obtain an oxy hemoglobin concentration mapover cerebral *** the separation of arteries and veins was accomplished by Otsuthreshold segmentation algorithm based on the OIS information and segmentation of ***,the segmentation and separation performances were assessed using area overlap measure(AOM).The segmentation and separation of cerebral vessels in cortical optical imaging have great potential applications in full-field cerebral hemodynamics monitoring and pathological study of cerebral vascular diseases,as well as in clinical intraoperative monitoring.

关键词： Vessel segmentation laser speckle imaging optical intrinsic signals imaging regiongrowing algorithm artery-vein separation.

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不同强度的抗阻运动对肺癌伴癌因性疲乏患者内分泌激素的调节作用

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医疗装备 2024年第12期37卷 5-8页

作者：许海阳孙巧丹卢红阳浙江省台州医院浙江台州317000

目的探讨不同强度的抗阻运动对肺癌伴癌因性疲乏(CRF)患者内分泌激素的调节作用。方法选择2020年1月至2023年10月于医院就诊的90例肺癌伴CRF患者为研究对象,采用随机数字表法分为试验组和对照组,每组45例。试验组予60%肌肉一次最大重... 详细信息

目的探讨不同强度的抗阻运动对肺癌伴癌因性疲乏(CRF)患者内分泌激素的调节作用。方法选择2020年1月至2023年10月于医院就诊的90例肺癌伴CRF患者为研究对象,采用随机数字表法分为试验组和对照组,每组45例。试验组予60%肌肉一次最大重复负荷(1-RM)抗阻运动,对照组予40%1-RM抗阻运动,两组均进行8周抗阻运动。比较两组治疗前及治疗8周后血清甲状腺激素[三碘甲状腺原氨酸(T_(3))和四碘甲状腺原氨酸(T_(4))]和皮质醇(Cor)水平、疲乏症状(MFSI-SF)及临床疗效。结果治疗8周后,两组血清T_(3)、T_(4)和Cor水平均高于治疗前,且试验组高于对照组,差异有统计学意义(P <0.05);两组MFSI-SF评分均低于治疗前,且试验组低于对照组,差异有统计学意义(P <0.05);试验组临床总有效率高于对照组,差异有统计学意义(P <0.05)。结论不同强度的抗阻运动均可在一定程度上调整肺癌伴CRF患者内分泌激素、疲乏症状,具有较好的临床疗效,其中60%1-RM的抗阻运动改善效果更明显。

关键词：肺癌癌因性疲乏抗阻运动内分泌激素

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医院中成药带量采购实施情况与管理对策

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中医药管理杂志 2024年第12期32卷 70-72页

作者：卢红阳王美娇王丽丽浙江省台州医院浙江台州317000 南京中医药大学卫生经济管理学院江苏南京210000

目的:结合国家医疗行业带量采购政策的颁布实施、医疗产品带量采购实施的具体情况,提出适合医院中成药带量采购的管理对策。方法:主要运用观察法、统计分析法、定性分析法等研究方法对某院中成药带量采购实施情况、现状进行分析,探究该... 详细信息

目的:结合国家医疗行业带量采购政策的颁布实施、医疗产品带量采购实施的具体情况,提出适合医院中成药带量采购的管理对策。方法:主要运用观察法、统计分析法、定性分析法等研究方法对某院中成药带量采购实施情况、现状进行分析,探究该政策执行对医疗机构、中成药企业及患者产生的影响,总结得出中成药带量采购实施效果及存在的突出问题。结果:医院中成药带量采购的实施,实现了降低中成药采购价格,保证了患者合理用药、科学用药、经济用药目标的顺利实现。结论:医院中成药带量采购的实施,应重点围绕科学确定带量采购药品价格区间、选择“代表品”报价来实施竞价、进一步完善定量采购的奖惩制度、保障集采药品供应,发挥信用评价作用等几个方面采取措施,来增强医院中成药带量采购的实效性,以创新中成药集采模式,开辟药品集采新领域,为后期广泛开展中成药集采奠定基础。

关键词：带量采购中成药价格发展

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Convolutional Sparse Coding in Gradient Domain for MRI Reconstruction

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自动化学报 2017年第10期43卷 1841-1849页

作者： Jiaojiao Xiong hongyang lu Minghui Zhang Qiegen Liu School of Information Engineering Nanchang University Nanchang 330031 China School of Electrical and Computer Engineering University of Calgary Calgary AB T2N 1N4 Canada

Magnetic resonance imaging (MRI) reconstruction from undersampled data has always been a challenging and fascinating task due to its implicit ill-posed nature and its significance accompanied with the emerging compressed sensing (CS) theory. Most state-of-the-art sparse representation based CS approaches partition the image into overlapped patches, and process each patch separately. These methods, however, lose important spatial structures of the signal of interest, and ignore the consistency of pixels, which is a strong constraint for MR image. In this paper, we propose a new reconstruction method, which builds on recently introduced ideas of convolutional sparse coding in gradient domain (GradCSC) to address above mentioned issue. As opposed to patch-based methods, GradCSC directly operates on the whole gradient image to capture the correlation between local neighborhoods and exploits the gradient image global correlation to produce better edges and sharp features of gradient image. It enables local features implicitly existed in the gradient images to be captured effectively. Extensive experimental results demonstrate that the proposed algorithm achieves higher quality reconstructions than alternative methods and converges quickly at various sampling schemes and $k$-space acceleration factors.

关键词：梯度图像稀疏编码 MRI 卷积应用分割图像空间采样磁共振成像

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Gradient-Based Low Rank Method for Highly Undersampled Magnetic Resonance Imaging Reconstruction

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Journal of Shanghai Jiaotong university(Science) 2018年第3期23卷 384-391页

作者： XU Xiaoling LIU Yiling LIU Qiegen lu hongyang ZHANG Minghui Department of Electronic Information Engineering Nanchang University Nanchang 330031 China

Recently, exploiting low rank property of the data accomplished by the non-convex optimization has shown great potential to decrease measurements for compressed sensing. In this paper, the low rank regularization is adopted to gradient similarity minimization, and applied for highly undersampled magnetic resonance imaging(MRI) reconstruction, termed gradient-based low rank MRI reconstruction(GLRMRI). In the proposed method,by incorporating the spatially adaptive iterative singular-value thresholding(SAIST) to optimize our gradient scheme, the deterministic annealing iterates the procedure efficiently and superior reconstruction performance is achieved. Extensive experimental results have consistently demonstrated that GLRMRI recovers both realvalued MR images and complex-valued MR data accurately, especially in the edge preserving perspective, and outperforms the current state-of-the-art approaches in terms of higher peak signal to noise ratio(PSNR) and lower high-frequency error norm(HFEN) values.

关键词： magnetic resonance imaging(MRI) low rank image gradients sparse representation deterministic annealing

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Two-Level Bregman Method for MRI Reconstruction with Graph Regularized Sparse Coding

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Transactions of Tianjin University 2016年第1期22卷 24-34页

作者：刘且根卢红阳张明辉 Department of Electronic Information Engineering Nanchang University

In this paper, a two-level Bregman method is presented with graph regularized sparse coding for highly undersampled magnetic resonance image reconstruction. The graph regularized sparse coding is incorporated with the two-level Bregman iterative procedure which enforces the sampled data constraints in the outer level and updates dictionary and sparse representation in the inner level. Graph regularized sparse coding and simple dictionary updating applied in the inner minimization make the proposed algorithm converge with a relatively small number of iterations. Experimental results demonstrate that the proposed algorithm can consistently reconstruct both simulated MR images and real MR data efficiently, and outperforms the current state-of-the-art approaches in terms of visual comparisons and quantitative measures.

关键词： magnetic resonance imaging graph regularized sparse coding dictionary learning Bregman iterative method alternating direction method

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Inducing piezoelectricity in distorted rutile TiO_(2)for enhanced tetracycline hydrochloride degradation through photopiezocatalysis

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Journal of Advanced Ceramics 2024年第3期13卷 323-331页

作者： Taotao Xia Lizhen lu Haoyu Zhang Jinghui Wang Zonghe Huang hongyang Wang Weiyi Yang Shuang Gao Qi Li Key Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

Various material design strategies have been developed to enhance photocatalytic performance of TiO_(2).However,no report is available on applications of the photopiezocatalysis strategy on TiO_(2)due to its lack of *** we developed a low-temperature molten salt etching process to create rutile TiO_(2)nanoparticles by etching[MgO_(6)]octahedrons away from MgTiO_(3)by molten NH_(4)Cl,during which a lattice distortion occurred in TiO_(2).The lattice distortion broke the structure symmetry of rutile TiO_(2)and subsequently endowed these rutile TiO_(2)nanoparticles with an unusual piezoelectric response with the maximum effective piezoelectric coefficient(d_(33))of~41.6 pm/V,which had not previously been found in TiO_(2)***,the photopiezocatalysis strategy was applied for the first time to enhance the photocatalytic performance of these TiO_(2)*** creation of lattice distortion to induce piezoelectricity could be extended to other photocatalysts that the photopiezocatalysis strategy has not been applied to and may generate novel functionalities for various technical applications.

关键词： photocatalysis TiO_(2) piezocatalysis molten salt etching process photopiezocatalysis

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基于小波理论的信号分析研究

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微计算机信息 2008年第7期24卷 280-281,115页

作者：黎梨苗桂林工学院电子与计算机系广西桂林541004

本文研究了信号的正交小波Mallat快速算法与小波包分析,给出了小波变换在信号消噪中的应用,并以Lab Windows/CVI和Mallat混合编程实现了小波消噪,大大减少了信号的干扰。

关键词：快速算法小波变换信号分析小波包

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CE-MU-OFDM-PM Signal Design and Analysis for Navcom

CE-MU-OFDM-PM Signal Design and Analysis for Navcom

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第十三届中国卫星导航年会

作者： Jing Ji Wei Chen Yuting Liu luyao Du hongyang lu School of Information Engineering Wuhan University of Technology Wuhan Xingtu Electronics Co. Ltd. School of Automation Wuhan University of Technology Department of Navigation CTTIC

With the successive large-scale launches of low-earth orbit satellites（LEOs）, satellite-based augmentation systems（SBAS） have become an important supplementary part of the GNSS system. However, the emergence of new concepts such as B5 G/6 G, national integrated positioning, navigation and timing systems（PNTs）, has brought new challenges to the integration of navigation and communication（NavCom）, but the core issue is still the challenge of the signal system. This paper proposes a new signal scheme. Through preliminary research on the same frequency band or adjacent frequency bands, it is found that this scheme is more suitable for S-band and has a wider normalized power spectral density（PSD） and peak sidelobe ratio（PSR）. And the multi-peak characteristics of autocorrelation. Through the analysis of simulation performance evaluation, it is found that the proposed scheme has high potential positioning accuracy. The code tracking accuracy can reach 0.85 meters and the carrier-tonoise ratio（CNR） is 20 dB?Hz. The proposed signal has less mutual influence with other candidate signals, and has better anti-multipath ability. At the same time, it is in terms of code tracking anti-matching spectrum interference factor, demodulation anti-matching spectrum interference factor, and demodulation anti-narrowband interference factor, the proposed signal also has excellent performance. Therefore, from the perspective of technical feasibility and theoretical evaluation, the signal proposed in this paper is superior to other candidate signals. And from an application point of view, the solution we propose can be used as a competitive potential signal solution for BDS in the future, and it is also B5 G/6 G foundation and PNT.

关键词： Signal design LEOs NavCom BDS PNTs CE-MU-OFDM-PM

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A Meta-Analysis of Randomized Controlled Trials Comparing Early to Late Concurrent Thoracic Radiotherapy with Etoposide and Cisplatin/Carboplatin Chemotherapy for Limited-Disease Small Cell lung Cancer

A Meta-Analysis of Randomized Controlled Trials Comparing Ea...

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抗肿瘤药物研究新进展与肿瘤个性化药物治疗论坛

作者： hongyang lu luo Fang Xiaojia Wang Jvfen Cai Weimin Mao Zhejiang Key Laboratory of Diagnosis and Treatment Technology on Thoracic Oncology(lung and Esophagus) Zhejiang Cancer Hospital

[Purpose]-To clear the optimal time of concurrent thoracic radiotherapy(TRT) with etoposide and cisplatin/carboplatin(EP/EC) chemotherapy for limited-disease small cell lung cancer (LD SCLC). [Materials and methods]-Randomized controlled trials were identified according to MEDLINE,the Cochrane Central Register of Controlled Trials,EMBASE,and so on comparing early to late concurrent TRT with EP/EC chemotherapy for LD *** thoracic radiotherapy(ERT) was defined as beginning radiation within 30 days after the start of *** are three eligible randomized controlled trials. [Results]- No significance difference in objective response was detected between early concurrent TRT and late concurrent TRT(RR:1.01,95%CI 0.86-1.18,P=0.90).Similar result was detected in 1-,2-,3- and 5-year survival rates between early concurrent TRT and late concurrent TRT(RR:1.06,95%CI 0.88-1.27,P=0.56;RR:1.15,95%CI 0.77- 1.71,P=0.49;RR:0.90,95%CI 0.66-1.22,P=0.49;RR:1.18,95%CI 0.64-2.16,P= 0.60).Total grade 3-4 adverse events including anemia,leucopenia,neutropenia, thrombocytopenia,nausea and vomiting,infection,esophageal toxicity,pulmonary toxicity, alopecia and hemorrhage in early concurrent TRT were significantly higher than that in late concurrent TRT(RR:1.21,95%CI 1.03-1.43,P=0.02). [Conclusion]-The result of our work indicates that survival rate of LD-SCLC with late concurrent TRT combined EP/EC chemotherapy is similar with early concurrent TRT, while grade 3-4 adverse events were less.

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