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EPIMEDOKOREANONE A FROM THE AERIAL PARTS O FEPIMEDIUM KOREANUM NAKAI

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Chinese Chemical Letters 1996年第1期7卷 23-24页

作者： Li, WK Yang, JS Xiao, PG Pan, JQ lu, mj Zhang, RY CHINESE ACAD MED SCI INST MED PLANT DEVBEIJING 100094PEOPLES R CHINA BEIJING UNION MED COLL BEIJING 100094PEOPLES R CHINA BEIJING UNIV DEPT CHEMBEIJING 100871PEOPLES R CHINA BEIJING MED UNIV SCH PHARMACEUT SCIBEIJING 100083PEOPLES R CHINA

A new alpha-pyrone derivative, epimedokoreanone A was isolated from the aerial parts of Epimedium koreanum Nakai. Its structure was determined by spectroscopic methods (IR, MS, H-1 NMR, C-13 NMR, DEPT, H-1-C-13 COSY a...

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SYNTHESIS　OF　FULLERENE　PYRROLIDINES　CONTAINING　SUBSTITUTED　PHENYL　GROUPS　THROUGH　AZOMETHINE　YLIDE　ADDITION

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Chinese Chemical Letters 1995年第12期6卷 1033-1036页

作者： Zhou, DJ Gan, LB Tan, HS luo, CP Huang, CH Pan, JQ lu, mj Wu, Y Beijing Univ State Key Lab Rare Earth Mat Chem & Applicat Beijing 100871 Peoples R China Beijing Univ Dept Chem Ctr Anal & Measurement Beijing 100871 Peoples R China Beijing Inst Microchem Beijing 100091 Peoples R China

Terephthalaldehyde reacts with sarcosine to form azomethine ylide, which adds to C60 according to a[3+2] cycloaddition process to form fullerene pyrrolidine. The same addition reaction can also be applied to other sub...

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一种基于新型计算机流体力学算法的血流储备分数在诊断缺血特异性冠状动脉疾病中的应用

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中华医学杂志 2021年第39期101卷 3252-3252页

作者：刘通源(编译) Tang CX Liu CY lu mj 东部战区总医院放射诊断科不详

基于冠状动脉计算机断层血管造影(CTA)的血流储备分数(CT-FFR)是一种评估冠状动脉疾病(CAD)生理意义的新技术。CT-FFR是一种强大的无创诊断工具,在评估心肌缺血、指导治疗策略以及提供预后信息方面都具有显著的潜力。其中HeartFlow的CT-... 详细信息

基于冠状动脉计算机断层血管造影(CTA)的血流储备分数(CT-FFR)是一种评估冠状动脉疾病(CAD)生理意义的新技术。CT-FFR是一种强大的无创诊断工具,在评估心肌缺血、指导治疗策略以及提供预后信息方面都具有显著的潜力。其中HeartFlow的CT-FFR算法(美国,HeartFlow公司)已经在3个多中心临床试验中得到验证。然而,HeartFlow的CT-FFR算法需要使用非现场的超级计算机进行计算。

关键词：血流储备分数多中心临床试验冠状动脉疾病无创诊断计算机断层计算机流体力学生理意义治疗策略

Molecular mechanisms of *** associated gastric carcinogenesis

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World Journal of Gastroenterology 1999年第5期5卷 369-374页

作者： Zhang ZW Farthing mj St Bartholomew's & the Royal London School of Medicine & Dentistry 英国

Study on incisional implantation of tumor cells by carbon dioxide pneumoperitoneum in gastric cancer of a murine model

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World Journal of Gastroenterology 1999年第6期5卷 544-546页

作者： Wang H Zheng MH Zhang HB Zhu J He JR lu AG Ji YB Zhang mj Jiang Y Yu BM Li HW Shanghai Second Med Univ Ruijin Hosp Dept Surg Shanghai 200025 Peoples R China Shanghai Inst Digest Surg Shanghai 200025 Peoples R China

INTRODUCTIONPort-site recurrence after laparoscopic tumor surgery is a frequent complication in cancer operations, such as gallbladder, stomach, ovary and colon[1-5]. The incidence of port-site recurrence after laparoscopic colectomy ranged from 1.1% to 6.3%, in contrast to a 0.68% tumor wound recurrence rate in patients undergoing curative open colectomy[6-8]. The possible mechanisms proposed were: ① contaminated laparoscopic instruments passing in and out of the port frequently; ② increased exfoliated cancer cells from laparoscopic manipulation; ③ adhered tumor cells by pneumoperitoneum[9-12]. Some experiments reported that desufflation related to seeding of port wounds via a stable suspension of tumor cells in CO2 gas was an unlikely cause of port tumors, some supported a direct intraperitoneal seeding of exfoliated tumor cells as its etiology and the instruments passing in and out of the port may play an important role in local recurrence[13-15]. The colon tumor cells were more common since laparoscopic colectomy was wildly performed.

关键词： stomach neoplasms colonic neoplasms cell movement carbon dioxide pneumoperitoneum murine model

Does in-house availability of multidisciplinary teams increase survival in upper gastrointestinal-cancer?

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World Journal of Gastrointestinal Oncology 2013年第3期5卷 60-67页

作者： Christian Kersten Milada Cvancarova Svein mjland Odd mjland Department of Oncology Southern Hospital Trust the Centre for Cancer Treatment Department of Oncology Southern Hospital Trust the Section of Abdominal Surgery Department of Abdominal Surgery Southern Hospital Trust

AIM: To investigate the effect of the establishment of in-house multidisciplinary team (MDT) availability (iMDTa) on survival in upper gastrointestinal cancer (UGI) patients. METHODS: In 2001, a cancer centre with irradiation and chemotherapy facilities was established in the Norwegian county of West Agder with a change of iMDTa (WA/MDT-Change). "iMDTa"-status was defined according to the availability of the necessary specialists within one institution on one campus, serving the population of one county. We compared survival rates during 2000-2008 for UGI patients living in counties with (MDT-Yes), without (MDT-No), with a mix (MDT-Mix) and WA/MDT-Change. Survival was calculated with Kaplan-Meier method. Cox model was used to uncover differences between counties with different MDT status when adjusted for age, sex and stage. RESULTS: We analyzed 395 patients from WA/MDT-Change and compared their survival to 12 135 UGIpatients from four other Norwegian regions. Median overall survival for UGI patients in WA/MDT-Change increased from 129 to 300 d from 2000-2008, P = 0.001. The regions with the highest level of iMDTa achieved the largest decrease in risk of death for UGI cancers (compared to the county with MDT-Mix: MDT-Yes 11%, P <0.05 and WA/MDT-Change 15%, P < 0.05). Analyzing the different tumour entities separately, patients living in the WA/MDT-Change county reached a statisti-cally significant reduction in the risk of death [hazard ratios (HR)] compared to patients in the county with MDT-Mix for oesophageal and gastric, but not for pan-creatic cancer. HR for the study period 2000-2004 are given first and then for the period 2005-2008: The HR for oesophageal cancers was reduced from [HR = 1.12; 95%CI: 0.75-1.68 to HR = 0.60, 95%CI: 0.38-0.95] and for gastric cancers from [HR = 0.87, 95%CI: 0.66-1.15 to HR = 0.63, 95%CI: 0.43-0.93], but not for pancreatic cancer [HR = 1.04-, 95%CI: 0.83-1.3 for 2000-2004 and HR = 1.01, 95%CI: 0.78-1.3 for 2005-2008]. UGI patients

关键词： Gastric cancer Gastroesophageal cancer Oesophageal cancer Pancreatic cancer Multidisci-plinary treatment Multidisciplinary team Survival

ON SEVERAL NEW METHODS TO POLAR DECOMPOSITION COMPUTATION

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Acta Mechanica Solida Sinica 1998年第4期11卷 329-340页

作者： Huang, mj Li, M Fu, MF Nanchang Univ Inst Engn Mech Nanchang 330029 Peoples R China

In this paper, the polar decomposition of a deformation gradient tensor is analyzed in detail. The four new methods for polar decompositioncomputation are given: (1) the iterated method, (2) the principal invariant's method, (3) the principal rotation axis' s method, (4) the coordinate transformation's method. The iterated method makes it possible to establish the nonlinear finite element method based on polar decomposition. Furthermore, the material time derivatives of the stretch tensor and the rotation tensor are obtained by explicit and simple expressions.

关键词： polar decomposition deformation gradient stretch tensor rotation tensor large deformation and large rotation

Hip prosthetic loosening:A very personal review

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World Journal of Orthopedics 2021年第9期12卷 629-639页

作者： Bengt mjöberg Department of Orthopedics Lund UniversityLund SE-22100Sweden

Hip prosthetic loosening is often difficult to detect at an early stage,and there has been uncertainty for a long time as to when the loosening occurs and thus to the basic *** comparing different diagnostic methods,we found that loosening is best defined as prosthetic migration and measured by radiostereometric *** evidence indicates that poor interlock,poor bone quality,and resorption of a necrotic bone bed may initiate loosening during or shortly after surgery;this forms the basis of the theory of early *** factors do affect the subsequent progression of loosening,which may increase subclinically during a long period of ***,the loosening may be detected on standard radiographs and may be interpreted as late loosening but should to be interpreted as late detection of *** theory of early loosening explains the rapid early migration,the development of periprosthetic osteolysis and granulomas,the causality between wear and loosening,and largely the epidemiology of clinical failure of hip *** discussed are definition of loosening,the pattern of early migration,the choice of migration threshold,the current understanding of loosening,a less exothermic bone cement,cemented taper-slip stems,a new exciting computed tomography-based technique for simpler implant migration studies,and research suggestions.

关键词： Hip prosthesis Prosthesis failure Radiostereometric analysis Bone resorption Bone cements Radionuclide imaging

In Memorium John ***(1919-2002)

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Episodes 2003年第1期26卷 47-48页

作者： Gryc, G Terman, mj US Geol Survey MS 975 Menlo Pk CA 94025 USA US Geol Survey MS 917 Reston VA USA