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COVID-19 vaccines and beyond

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Cellular & Molecular Immunology 2024年第3期21卷 207-209页

作者： yiyuan Liu Danying Li Jiahuai Han State Key Laboratory of Cellular Stress Biology Innovation Center for Cell BiologySchool of Life SciencesXiamen UniversityXiamenFujianChina Laboratory Animal Center Xiamen UniversityXiamenFujianChina Research Unit of Cellular Stress of CAMS Cancer Research Center of Xiamen UniversityXiang’an Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamenFujianChina

Hundreds of vaccines have been developed worldwide for Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the cause of Coronavirus disease 2019(COVID-19),since the beginning of the *** vaccines have saved innumerable lives and contributed to partial control of the COVID-19 *** of the vaccines approved for clinical use exhibit satisfactory initial protection rates against corresponding ***,vaccine protection declines over time,with almost all vaccines falling below 50%protection after 6 months[1].In the case of natural infections,protection lasts longer,but the incidence of reinfection is also quite high.

关键词： vaccines acute beyond

BIOOXIDATION OF TWO ARSENICAL REFRACTORY GOLD CONCENTRATES AND GOLD CYANIDATION

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中国有色金属学会会刊：英文版 1994年第3期4卷 41-45页

作者： Zhang, Yongzhu lu, yiyuan Zhang, Chuanfu Zhao, Tiancong(Deptartment.of Nonferrous Metallurgy,Central South University of Technology, 410083 Changsha)Qiu , Rongqing(Microbilolgy Institute, Academia Sinica,Beijing 100080)

ＢＩＯＯＸＩＤＡＴＩＯＮＯＦＴＷＯＡＲＳＥＮＩＣＡＬＲＥＦＲＡＣＴＯＲＹＧＯＬＤＣＯＮＣＥＮＴＲＡＴＥＳＡＮＤＧＯＬＤＣＹＡＮＩＤＡＴＩＯＮＺｈａｎｇ，Ｙｏｎｇｚｈｕ；Ｌｕ，Ｙｉｙｕａｎ；Ｚｈａｎｇ，Ｃｈｕａｎｆｕ；... 详细信息

ＢＩＯＯＸＩＤＡＴＩＯＮＯＦＴＷＯＡＲＳＥＮＩＣＡＬＲＥＦＲＡＣＴＯＲＹＧＯＬＤＣＯＮＣＥＮＴＲＡＴＥＳＡＮＤＧＯＬＤＣＹＡＮＩＤＡＴＩＯＮＺｈａｎｇ，Ｙｏｎｇｚｈｕ；Ｌｕ，Ｙｉｙｕａｎ；Ｚｈａｎｇ，Ｃｈｕａｎｆｕ；Ｚｈａｏ，Ｔｉａｎｃｏｎｇ（Ｄｅｐ...

关键词： gold bacterial leaching refractory gold ores

Impact Performance Research of Re-Entrant Octagonal Negative Poisson’s Ratio Honeycomb with Gradient Design

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 3105-3119页

作者： yiyuan Li Yongjing Li Shilin Yan Pin Wen Department of Engineering Structure and Mechanics Wuhan University of TechnologyWuhan430070China Hubei Key Laboratory of Theory and Application of Advanced Materials Mechanics School of ScienceWuhan University of TechnologyWuhan430070China

Based on the traditional re-entrant honeycomb,a novel re-entrant octagon honeycomb(ROH)is *** deformation mode of the honeycomb under quasi-static compression is analyzed by numerical simulation,and the results are in good agreement with the experimental *** deformation modes,mechanical properties,and energy absorption characteristics of ROH along the impact and perpendicular directions gradient design are investigated under different *** results indicated that the deformation mode of ROH is affected by gradient design along the direction of impact and impact *** addition,gradient design along the direction of impact can increase the initial peak stress of ROH and accelerate its densification *** design perpendicular to the impact direction can enhance the energy absorption performance of ROH,especially for ROH,with wall thickness increasing from the inside *** to ROH with uniform wall thickness at the same relative density,ROH with a gradient design can increase the plateau stress by over *** the elevation of impact velocity,the plateau stress and specific energy absorption exhibit an upward trend,aligning with the dynamic performance pattern observed in conventional *** results can be used as a reference for the design and application of honeycomb and provide a new idea for developing more efficient and reliable energy-absorbing materials.

关键词： Re-entrant honeycomb gradient design finite element analysis additive manufacturing technologies

Musculoskeletal ultrasound to evaluate the efficacy of acupuncture: a review

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Journal of Traditional Chinese Medicine 2024年第3期44卷 629-632页

作者： WANG Dingyue YU Yana WANG yiyuan ZHANG Zhen Department of Ultrasound the First Affiliated Hospital of China Medical UniversityShenyang 110001China

Acupuncture is a typical example of Traditional Chinese Medicine and has been used in China for hundreds of years to treat a wide range of illnesses. However, in the clinic, issues and deficiencies were primarily seen in four areas: loss of accuracy in the operation process;difficulty understanding the depth of acupuncture;difficulty using reinforcing and reducing techniques;and lack of a clear dynamic effect of acupuncture points following acupuncture. Musculoskeletal ultrasonography may quantitatively evaluate the acupuncture location and display the distribution of small nerves near and within the fascia of the acupuncture point in real time. The subjects were asked how they felt about receiving Qi when the needle body reached different depths and different tissues. The Qi obtained from an acupuncture point and the connective tissue of the fascia can be further understood by combining the physiological response of the acupuncture point with the anatomical structure,which offers a new method for defining the nature of the acupuncture point and standardizing the acupuncture point.

关键词： musculoskeletal ultrasound acupuncture De Qi dynamic effect visualization

DESIGH OF FOOD ECTUDER

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DESIGH OF FOOD ECTUDER

Quantitative analysis and prediction of the sound field convergence zone in mesoscale eddy environment based on data mining methods

'97北京国际食品加工及包装技术讨论会

作者： lu Wengchang Sun yiyuan (Jiangsu Unversity of Science and Technology)

＜正＞This paper discusses bascal design method of food extruder, extrusion theory and main part design. It describes the method of design small food extruder and supplies the reference to designer for use.

关键词： Food Extruder Similarity theory Designed method

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cnki会议

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Acta Oceanologica Sinica 2024年第5期43卷 110-120页

作者： Ming Li Yuhang Liu yiyuan Sun Kefeng Liu College of Advanced Interdisciplinary Studies National University of Defense TechnologyNanjing 211101China Jiangsu Ocean University Lianyungang 222061China College of Horticulture Forestry Sciences Huazhong Agricultural UniversityWuhan 430070China

The mesoscale eddy(ME)has a significant influence on the convergence effect in deep-sea acoustic *** paper use statistical approaches to express quantitative relationships between the ME conditions and convergence zone(CZ)*** on the Gaussian vortex model,we construct various sound propagation scenarios under different eddy conditions,and carry out sound propagation experiments to obtain simulation *** a large number of samples,we first adopt the unified regression to set up analytic relationships between eddy conditions and CZ *** sensitivity of eddy indicators to the CZ is quantitatively ***,we adopt the machine learning(ML)algorithms to establish prediction models of CZ parameters by exploring the nonlinear relationships between multiple ME indicators and CZ *** the research,we can express the influence of ME on the CZ quantitatively,and achieve the rapid prediction of CZ parameters in ocean *** prediction accuracy(R)of the CZ distance(mean R:0.9815)is obviously better than that of the CZ width(mean R:0.8728).Among the three ML algorithms,Gradient Boosting Decision Tree has the best prediction ability(root mean square error(RMSE):0.136),followed by Random Forest(RMSE:0.441)and Extreme Learning Machine(RMSE:0.518).

关键词： convergence zone mesoscale eddy statistic analysis quantitative prediction machine learning

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美国网络免税相关法案的发展和借鉴

涉外税务 2009年第5期 44-48页

作者：卢锐邢怡媛中山大学岭南学院广东广州510275

自网络经济出现以来,快速发展的宽带连接和各种电子支付方式给美国税收管理带来了许多问题,也推动了美国政府制定统一的网络税收政策。本文全面介绍了美国网络免税相关法案的内容及其产生和发展的过程,并结合美国两大权威组织的研究报告... 详细信息

自网络经济出现以来,快速发展的宽带连接和各种电子支付方式给美国税收管理带来了许多问题,也推动了美国政府制定统一的网络税收政策。本文全面介绍了美国网络免税相关法案的内容及其产生和发展的过程,并结合美国两大权威组织的研究报告,对电子商务税收的关键问题进行了分析,以期对我国今后制定有关电子商务的税收政策有所借鉴。

关键词：美国网络免税法电子商务税收政策

QUANTUM CHEMICAL STUDY ON THE REACTION OF PYRITE WITH NITRIC ACID^+

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Journal of Central South University 1995年第1期7卷 25-28页

作者： Yang Tianzu Zhao Tiancong lu yiyuan (Department of Nonferrous Metallurgy, Central South University of Technology, Changsha, 410083, China)

The reaction of pyrite with nitric acid was studied using CNDO/2 method. Strong coordinate bond and back π bond between Pe2+and are formed in pyrite. In nitric acid solution when acts on the surface of pyrite the to... 详细信息

关键词： pyrite nitric acid quantum chemistry

African swine fever virus MGF505-3R inhibits cGAS-STING-mediated IFN-βpathway activation by degrading TBK1

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Animal Diseases 2022年第3期2卷 154-164页

作者： Mingyang Cheng Jiawei luo Yuetong Duan Yu Yang Chunwei Shi Yu Sun yiyuan lu Junhong Wang Xiaoxu Li Jianzhong Wang Nan Wang Wentao Yang Yanlong Jiang Guilian Yang Yan Zeng Chunfeng Wang Xin Cao College of Veterinary Medicine Jilin Agricultural UniversityChangchunChina Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding Jilin Agricultural UniversityChangchunChina Jilin Provincial Engineering Research Center of Animal Probiotics Jilin Agricultural UniversityChangchunChina Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education Jilin Agricultural UniversityChangchunChina

African swine fever virus(ASFV)is an important pathogen causing acute infectious disease in domestic pigs and wild boars that seriously endangers the global swine *** ASFV is structurally complex and encodes a large number of functional proteins,no effective vaccine has been developed to ***,dissecting the mechanisms of immune escape induced by ASFV proteins is crucial.A previous study showed that the ASFV-encoded protein is an important factor in host *** this study,we identified a negative regulator,MGF505-3R,that significantly downregulated cGAS/STING-and poly(dG:dC)-mediated IFN-βand interferon stimulation response element(ISRE)reporter activity and suppressed IFNB1 and IFIT2 mRNA *** addition,TBK1,IRF3 and IκBαphosphorylation levels were also ***,MGF505-3R interacted with cGAS/TBK1/IRF3 and targeted TBK1 for degradation,thereby disrupting the cGAS-STING-mediated IFN-βsignaling pathway,which appears to be highly correlated with *** MGF505-3R expression enhanced IFN-βand IL-1β*** together,our study revealed a negative regulatory mechanism involving the MGF505-3R-cGAS-STING axis and provided insights into an evasion strategy employed by ASFV that involves autophagy and innate signaling pathways.

关键词： African swine fever virus MGF505-3R cGAS/STING signaling pathway TBK1 Innate immunity