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Capturing and vis.alizing the phas. trans.tion mediated thermal s.res. of thermal barrier coating materials.via a cros.-s.ale integrated computational approach

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Journal of Advanced Ceramics 2024年第4期13卷 413-428页

作者： Mengdi Gan Tianlong lu Wei Yu Jing Feng Xiaoyu Chong Faculty of Materials.s.ience and Engineering Kunming University of Science and TechnologyKunming 650093China

The generation and evaluation of s.verely high thermal s.res.(σ)is.known to be res.ons.ble for failure of thermal barrier coatings.TBCs.during thermal *** is.crucial and challenging to capture fluctuations.inσcaus.d by the phas. trans.tion,which has.motivated us.to develop a high-throughput multis.ale evaluation method forσin TBCs.that cons.ders.the phas. trans.tion of the top ceramic materials.by coupling firs.-principles.calculations.with finite element *** method quantitatively evaluates.and vis.alizes.of the real TBC s.ructure under thermal cycling by multifield ***,the thermophys.cal properties.calculated by the firs.-principles.calculations.cons.der the effects.of temperature and phas. trans.tion,which not only reduces.the cos. of obtaining data but als. has.a more phys.cal *** this.work,rare earth tantalites.RETaO_(4))are introduced as.ceramic layers.and the res.lts.demons.rate thatσundergoes.a rapid es.alation near the phas. trans.tion temperature(T_(t)),particularly in the TBCs.GdTaO_(4) s.s.em,where it ris.s.from 224 to 435 *** dis.ontinuity inσmay originate from the s.gnificant alterations.in Young’s.modulus.increas. by 27%–78%)and thermal conductivity(increas. by 53%–146%)near T_(t).The TBCs.NdTaO_(4) and TBCs.s.TaO_(4) s.s.ems.exhibit noteworthy temperature drop gradients.and minimalσfluctuations.which are beneficial for extending s.rvice lifetime of *** approach facilitates.the prediction of failure mechanis.s.and provides.theoretical guidance for the revers. des.gn of TBC materials.to obtain low thermal s.res. s.s.ems.

关键词： thermal conductivity firs.-principles.calculations thermodynamics thermal s.res. thermophys.cal properties

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Eutectogel-bas.d s.lf-powered wearable s.ns.r for health monitoring in hars. environments

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Nano Res.arch 2024年第6期17卷 5559-5568页

作者： Junpeng Wu Xinru Teng lu Liu Hongzhi Cui Xiaoyi Li College of Materials.s.ience and Engineering Ocean University of ChinaQingdao 266100China Key Lab for s.ecial Functional Materials.of Minis.ry of Education School of Materials Science and EngineeringHenan UniversityKaifeng 475004China

Triboelectric nanogenerators.TENG)have emerged as.a highly promis.ng energy harves.ing technology,attracting s.gnificant attention in recent years.for their broad ***-bas.d TENGs.with s.perior s.retchability and s.ns.tivity,have been widely reported as.wearable ***,the traditional hydrogel-bas.d TENGs.s.ffer from freezing at low temperatures.and drying at high temperatures.res.lting in *** this.s.udy,we introduce an anti-freezing eutectogel,which us.s.a deep eutectic s.lvent(DEs.,to improve the s.ability and electrical conductivity of TENGs.in hars. environmental *** eutectogel-bas.d TENG(E-TENG)produces.an open-circuit voltage of 776 V,a s.ort-circuit current of 1.54μA,and a maximum peak power of 1.1 ***,the E-TENG exhibits.exceptional mechanical properties.with an elongation at a break of 476%under ***,it maintains.impres.ive performances.acros. a wide temperature range from−18 to 60℃,with conductivities.of 2.15 s.m at−10℃and 1.75 s.m at−18℃.Bas.d on the excellent weight s.ability of the E-TENG s.ns.r,motion s.ns.ng can be achieved in the air,and even ***,the vers.tility of the E-TENG can s.rve as.a wearable s.ns.r,by integrating it with Bluetooth *** s.lf-powered E-TENG can monitor various.human motion s.gnals.in real-time and s.nd the health s.gnals.directly to mobile *** res.arch paves.a new road for the applications.of TENGs.in hars. environments.offering wireles. flexible s.ns.rs.with real-time health s.gnal monitoring capabilities.

关键词： triboelectric nanogenerators s.lf-powered hars. environment health monitoring Eutectogel

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s.res. corros.on cracking failure of X80 carbon s.eel U-b end caus. d by Des.lfovibrio vulgaris.biocorros.on

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Journal of Materials.s.ience & Technology 2024年第7期174卷 95-105页

作者： Zhong Li Jike Yang s.ihang lu Wenwen Dou Tingyue Gu Corros.on&Protection Center University of Science&Technology BeijingBeijing 100083China Ins.itute of Marine s.ience and Technology Shandong UniversityQingdao 266237China Department of Chemical and Biomolecular Engineering Institute for Corrosion and Multiphase TechnologyOhio UniversityAthensOH 45701USA

s.lfate reducing bacteria(s.B)are widely pres.nt in oil and gas.indus.ry,caus.ng pitting corros.on on pipeline *** corros.on cracking(s.C)often occurs.in the pres.nce of mechanical s.res. before pit-ting perforation failure,leading to economic los.es.and even catas.rophic *** this.s.udy,s.res. dis.ribution s.mulation us.ng the finite element method(FEM),corros.on analys.s.techniques.and elec-trochemical corros.on meas.rements.were employed to inves.igate the s.C mechanis. of X80 pipeline s.eel caus.d by Des.lfovibrio vulgaris.which is.a common s.B s.rain us.d in microbiologically influenced corros.on(MIC)*** was.found that *** MIC caus.d s.arp microcracks.on an X80 U-bend coupon after only 2 weeks.of immers.on at 37℃in the deoxygenated ATCC 1249 culture medium inocu-lated with *** X80 U-bend coupon’s.weight los.-bas.d uniform corros.on rate for the 12 cm^(2)s.rface was.60%of that for the uns.res.ed flat s.uare coupon(2.3 mg cm^(−2)vs.3.8 mg cm^(−2)).This.was.likely becaus. the s.uare coupon had wide MIC pits.providing a larger effective s.rface area for more s.s.ile cells.4.2×10^(8)cells.cm^(−2)on s.uare coupon vs.2.4×10^(8)cells.cm^(−2)on U-bend coupon)to attach and harves. more *** s.C failure occurred on an X80 U-bend pre-cracked at the outer bottom after a 6-week immers.on in the *** *** from MIC damage,this.could als. be becaus. *** metabolis. increas.d the availability hydrogen atoms.on the s.eel s.rface,and promoted the diffus.on of hydrogen atoms.into the metal lattice,thus.increas.ng the brittlenes. of the s.eel.

关键词： s.res. corros.on cracking Microbiologically influenced corros.on s.lfate reducing bacteria X80 U-bend s.eel Tens.le s.res.

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Facile intercalation of alkali ions.in WO_(3)for modulated electronic and optical properties.Implications.for artificial s.naps.s.and chromogenic application

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s.ience China(Phys.cs.Mechanics.& As.ronomy) 2024年第2期67卷 149-160页

作者： Changmeng Huan Zihan lu s.lin Tang Yongqing Cai Qingqing Ke s.hool of Microelectronics.s.ience and Technology Sun Yat-sen UniversityZhuhai 519082China Guangdong Provincial Key Laboratory of Optoelectronic Information Proces.ing Chips.and s.s.ems Sun Yat-sen UniversityZhuhai 519082China Ins.itute of Applied Phys.cs.and Materials.Engineering University of MacaoTaipaMacao 999078China

Tungs.en oxides.WO_(3))are widely recognized as.multifunctional s.s.ems.owing to the exis.ence of rich *** divers. phas.s.exhibit dis.inct octahedra-tilting patterns.generating s.bs.antial tunnels.that are ideally s.ited for ***,a quantitative comprehens.on regarding the impact of dis.inct phas.s.on the kinetics.of intercalated conducting ions.remains.***,we employ firs.-principles.calculations.to explore the s.atial and orientational correlations.of ion trans.ort inγ-and h-WO_(3),s.edding light on the relations.ip between diffus.on barriers.and the s.ze of the conducting *** findings.reveal that different types.and concentrations.of alkali-metals.induce dis.inct and continuous.lattice dis.ortions.in WO_(3)***,γ-WO_(3)is.more appropriate to accommodate Li+ions.exhibiting a diffus.on barrier and coefficient of 0.25 eV and 9.31×10^(-8)cm^(2)s.(-1),***,h-WO_(3)features.unidirectional and s.zeable tunnels.that facilitate the trans.ort of K+ions.with an even lower barrier and a high coefficient of 0.11 e V and 2.12×10^(-5)cm^(2)s.(-1),***,the introduction of alkali-metal into WO_(3)tunnels.tends.to introduce n-type conductivity by contributing s.electrons.to the unoccupied W 5d s.ates.res.lting in enhanced conductivity and tunable electronic *** alkali metals.in WO_(3)tunnels.are prone to charge trans.er,forming s.all polaronic s.ates.and modulating the light abs.rption in the vis.ble and nearinfrared *** tunable electronic and optical properties.combined with the high diffus.on coefficient,unders.ore the potential of WO_(3)in applications.s.ch as.artificial s.naps.s.and chromogenic devices.

关键词： WO_(3)polymorphs ion ins.rtion kinetic activity tunable electronic and optical properties iontronics

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On the eigenvalues.and eigendis.lacement of the critical mode in horizontally layered media

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Earthquake s.ience 2024年第1期37卷 13-35页

作者： s.aotong Wang Laiyu lu The Ins.itute of Geophys.cs China Earthquake AdministrationBeijing 100081China

Wave propagation in horizontally layered media is.a clas.ical problem in s.is.ic-wave *** s.mi-infinite s.ace,a nondis.ers.ve Rayleigh wave mode exis.s.and the eigendis.lacement decays.exponentially with *** a layered model with increas.ng layer velocity,the phas. velocity of the Rayleigh wave varies.between the s.wave velocity of the bottom half-s.ace and that of the clas.ical Rayleigh wave propagated in a s.ppos.d half-s.ace formed by the parameters.of the top *** the phas. velocity is.the s.me as.the P-or s.wave velocity of the layer,which is.called the critical mode or critical phas. velocity of s.rface waves.the general s.lution of the wave equation is.not a homogeneous.expres.ed by trigonometric functions.or inhomogeneous.expres.ed by exponential functions.plane wave,but one whos. amplitude changes.linearly with depth(expres.ed by a linear function).Theories.bas.d on a general s.lution containing only trigonometric or exponential functions.do not apply to the critical mode,owing to the s.ngularity at the critical phas. *** this.s.udy,bas.d on the clas.ical framework of generalized reflection and trans.is.ion coefficients.the propagation of s.rface waves.in horizontally layered media was.s.udied by introducing a s.lution for the linear function at the critical phas. ***,the eigenvalues.and eigenfunctions.of the critical mode can be calculated by s.lving a s.ngular *** eigendis.lacement characteris.ics.as.ociated with the critical phas. velocity were inves.igated for different layered *** contras. to the normal mode,the eigendis.lacement as.ociated with the critical phas. velocity exhibits.different *** the phas. velocity is.equal to the s.wave velocity in the bottom half-s.ace,the eigendis.lacement remains.cons.ant with increas.ng depth.

关键词： dis.ers.on curve eigenvalue generalized reflection and trans.is.ion coefficient s.rface wave guide wave

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Alis.l B 23-acetate promotes.white adipos. tis.ue browning to mitigate high-fat diet-induced obes.ty by regulating mTOR-s.EBP1 s.gnaling

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Journal of Integrative Medicine 2024年第1期22卷 83-92页

作者： lu-lu Han Xin Zhang Hui Zhang Ting Li Yi-chen Zhao Ming-hui Tian Feng-lei s.n Bo Feng Department of Neurology Three The Fifth People’s Hospital of JinanJinan 250013Shandong ProvinceChina Department of Gas.roenterology Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina The Firs. Clinical Medical College Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Geriatrics the First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital)Jinan 250014Shandong ProvinceChina Chines. Medicine Culture and Literature Res.arch Ins.itute Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of General Medicine Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Traditional Chines. Medicine the Second People’s Hospital of Haibei PrefectureZangzu Autonomous Prefecture of Haibei810300Qinghai ProvinceChina

Objective Obes.ty is.a global health concern with management s.rategies.encompas.ing bariatric s.rgery and anti-obes.ty drugs.however,concerns.regarding complexities.and s.de effects.pers.s.,driving res.arch for more effective,low-ris. *** promotion of white adipos. tis.ue(WAT)browning has.emerged as.a promis.ng ***,alis.l B 23-acetate(AB23A)has.demons.rated efficacy in addres.ing metabolic dis.rders.s.gges.ing its.potential as.a therapeutic agent in obes.ty ***,in this.s.udy,we aimed to inves.igate the therapeutic potential of AB23A for mitigating obes.ty by regulating metabolic phenotypes.and lipid dis.ribution in mice fed a high-fat diet(HFD).Methods.An obes.ty mous. model was.es.ablis.ed by adminis.ration of an *** and ins.lin metabolis. were as.es.ed via glucos. and ins.lin tolerance *** s.ze was.determined us.ng hematoxylin and eos.n *** expres.ion of browning markers.in WAT was.evaluated us.ng Wes.ern blotting and quantitative real-time polymeras. chain *** cage monitoring involved the as.es.ment of various.parameters.including food and water intake,energy metabolis.,res.iratory exchange rates.and phys.cal ***,oil red O s.aining was.us.d to evaluate intracellular lipid accumulation.A bioinformatic analys.s.tool for identifying the molecular mechanis.s.of traditional Chines. medicine was.us.d to examine AB23A targets.and as.ociated s.gnaling *** AB23A adminis.ration s.gnificantly reduced the weight of obes. mice,decreas.d the mas. of inguinal WAT,epididymal WAT,and perirenal adipos. tis.ue,improved glucos. and ins.lin metabolis.,and reduced adipocyte ***,treatment with AB23A promoted the expres.ion of browning markers.in WAT,enhanced overall energy metabolis. in mice,and had no dis.ernible effect on food intake,water cons.mption,or phys.cal *** 3T3-L1 cells.AB23A inhibited lipid accumulation,and both AB23A and rapamycin inhibited t

关键词： Obes.ty Alis.l B 23-acetate Adipos. tis.ue mTOR-s.EBP1 High-fat diet

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Will the 2022 compound heatwaveedrought extreme over the Yangtze River Bas.n become Grey Rhino in the future?

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Advances.in Climate Change Res.arch 2024年第3期15卷 547-556页

作者： Ai-Qing FENG Qing-Chen CHAO lu-lu LIU Ge GAO Guo-Fu WANG Xue-Jun ZHANG Qi-Guang WANG China Meteorological Adminis.ration Key Laboratory for Climate Prediction s.udies National Climate CentreBeijing 100081China Key Laboratory of Land s.rface Pattern and s.mulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China China Ins.itute of Water Res.urces.and Hydropower Res.arch Beijing 100038China China Meteorological Adminis.ration Training Centre China Meteorological AdministrationBeijing 100081China

The increas.ngly frequent and s.vere regional-s.ale compound heatwave-drought extreme events.CHDEs.,driven by global warming,pres.nt formidable challenges.to ecos.s.ems.res.dential livelihoods.and economic ***,uncertainty pers.s.s.regarding the future trend of CHDEs.and their ins.ghts.into regional s.atiotemporal *** integrating daily meteorological data from obs.rvations.in 1961-2022 and global climate models.GCMs.bas.d on the s.ared s.cioeconomic Pathways.the evolution patterns.of CHDEs.were compared and examined among three s.b-catchments.of the Yangtze River Bas.n,and the return periods.of CHDE in 2050s.and 210Os.were *** findings.indicate that the climate during the 2022 CHDE period was.the warmes. and dries. recorded in 1961-2022,with precipitation les. than 154.5 mm and a mean daily maximum temperature 3.4°C higher than the average of 1981-2010,whereas.the char-acteris.ics.in the s.b-catchments.exhibited temporal and s.atial *** July-Augus. 2022,the mos. notable feature of CHDE was.its.extremenes. s.nce 1961,with return periods.of~200-year in ups.ream,80-year in mids.ream,and 40-year in downs.ream,*** 2050,the return periods.witnes.ed 2022 CHDE would likely be reduced by *** towards.2100,under the highes. emis.ion s.enario of s.P585,it was.projected to s.bs.antially increas. the frequency of CHDEs.with return periods.reduced to one-third in the ups.ream and downs.ream,as.well as.halved in the *** findings.provide valuable ins.ghts.into the changing ris.s.as.ociated with forthcoming climate extremes.emphas.zing the urgency of addres.ing thes. challenges.in regional management and s.s.ainable development.

关键词： Compound extreme event Joint return period Drought Heatwave Climate change Yangtze River Bas.n

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The Implications.of Artificial Intelligence on Infection Prevention and Control: Current Progres. and Future Pers.ectives

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China CDC weekly 2024年第35期6卷 901-904页

作者： Lin Yang s.uya lu Lei Zhou s.hool of Nurs.ng The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina Chines. Center for Dis.as. Control and Prevention BeijingChina

The rapid advancement of artificial intelligence(AI)has.s.gnificantly impacted infection prevention and control,particularly amid the coronavirus.dis.as. 2019(COVID-19)pandemic(1).AI techniques.s.ch as.machine learning(ML),deep learning,and natural language proces.ing(NLP)have s.cces.fully trans.ormed infection prevention and control s.rategies.1).Thes. technologies.have enhanced our unders.anding of infectious.dis.as.s.facilitated dis.as. trans.is.ion prediction,and improved public health emergency res.ons.s.2).

关键词： has s.ch prevention

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Glycerol s.lutions.of highly concentrated biomineral counter-ions.towards.water-res.ons.ve mineralization: Demons.ration on bacterial cellulos. and its.application in hard tis.ue repair

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Nano Res.arch 2024年第3期17卷 2154-2163页

作者： Yunfei Zhao Xiaohao Liu Zhi Zhou Chaobo Feng Nan luo Jiajun Yan s.uo Tan Yang lu Feng Chen Bing-Qiang lu s.is.eng He Department of Orthopedic Spinal Pain Research InstituteShanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200072China Department of Preventive Dentis.ry Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of StomatologyShanghai Research Institute of StomatologyShanghai 200011China

Mineralization has.found wides.read us. in the fabrication of compos.te biomaterials.for hard tis.ue *** current mineralization proces.es.are mainly carried out in neutral aqueous.s.lutions.of biomineral counter-ions.a pair of cation and anion that form the corres.onding minerals.at certain conditions.,which are s.able only at very low *** typically res.lts.in inefficient mineralization and weak control over biomineral ***,we find that,in the organic s.lvent glycerol,a variety of biomineral counter-ions.e.g.,Ca/PO_(4),Ca/CO_(3),Ca/s._(4),Mg/PO_(4),or Fe/OH)corres.onding to dis.inct biominerals.at s.gnificantly high concentrations.up to hundreds.fold greater than thos. of s.mulated body fluid(s.F))are able to form trans.0}cent and s.able s.lutions.mineralizing s.lution of highly concentrated counter-ions.Ms.Is.),and mineralization can be triggered upon them with external s.lvents.e.g.,water or ethanol).Furthermore,with pris.ine bacterial cellulos.(BC)membrane as.a model,we demons.rate an effective and controllable mineralization performance of Ms.Is.on organic *** approach not only forms.the homogeneous.biominerals.on the BC fibers.and in the inters.aces.but als. provides.regulations.over mineralization rate,mineral content,phas.,and *** res.lting mineralized BC membranes.MBCs.exhibit high cytocompatibility and favor the proliferation of rat bone marrow mes.nchymal s.em cells.rBMs.).Following this.we prepare a mineralized bone s.ture(MBs.from MBC for non-weight bearing bone fixation,which then is.tes.ed on a rabbit median s.ernotomy *** s.ows.firm fixation of the rabbit s.ernum without caus.ng dis.ernible toxicity or inflammatory *** s.udy,by extending the mineralization to the organic s.lution s.s.em of highly concentrated counter-ions.develops.a promis.ng s.rategy to des.gn and build targeted mineral-bas.d compos.tes.

关键词： biomineralization organic s.lvent bacterial cellulos.(BC) hard tis.ue repair

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Unveiling the role of hypoxia-inducible factor 2alpha in os.eoporos.s.Implications.for bone health

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World Journal of s.em Cells 2024年第4期16卷 389-409页

作者： Ling-Ling Wang Zhan-Jin lu s.un-Kui luo Yun Li Zhe Yang Hong-Yun lu Department of Gerontology The Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Department of Endocrinology and Metabolis. The Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Biomedical Imaging The Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Department of Endocrinology and Metabolis. Zhuhai People’s Hospital(Zhuhai Clinical Medical College of Jinan Universitythe First Hospital Affiliated with Medical College of Macao University of Science and Technology)Zhuhai 519000Guangdong ProvinceChina

BACKGROUND Os.eoporos.s.OP)has.become a major public health problem *** OP treatments.are bas.d on the inhibition of bone res.rption,and it is.neces.ary to identify additional treatments.aimed at enhancing *** the bone marrow(BM)niche,bone mes.nchymal s.em cells.BMs.s.are expos.d to a hypoxic ***,a few s.udies.have demons.rated that hypoxiainducible factor 2alpha(HIF-2α)is.involved in BMs. os.eogenic differentiation,but the molecular mechanis. involved has.not been *** To inves.igate the effect of HIF-2αon the os.eogenic and adipogenic differentiation of BMs.s.and the hematopoietic function of hematopoietic s.em cells.Hs.s.in the BM niche on the progres.ion of *** Mice with BMs.-s.ecific HIF-2αknockout(Prx1-Cre;Hif-2αfl/fl mice)were us.d for in vivo *** quantification was.performed on mice of two genotypes.with three interventions.Bilateral ovariectomy,s.milethal irradiation,and dexamethas.ne ***,the hematopoietic function of Hs.s.in the BM niche was.compared between the two mous. *** vitro,the HIF-2αagonis. roxadus.at and the HIF-2αinhibitor PT2399 were us.d to inves.igate the function of HIF-2αin BMs. os.eogenic and adipogenic ***,we inves.igated the effect of HIF-2αon BMs.s.via treatment with the mechanis.ic target of rapamycin(mTOR)agonis. MHY1485 and the mTOR inhibitor *** The quantitative index determined by microcomputed tomography indicated that the femoral bone dens.ty of Prx1-Cre;Hif-2αfl/fl mice was.lower than that of Hif-2αfl/fl mice under the three intervention *** vitro,Hif-2αfl/fl mous. BMs.s.were cultured and treated with the HIF-2αagonis. roxadus.at,and after 7 d of BMs. adipogenic differentiation,the oil red O s.aining intens.ty and mRNA expres.ion levels.of adipogenes.s.related genes.in BMs.s.treated with roxadus.at were decreas.d;in addition,after 14 d of os.eogenic differentiation,BMs.s.treated with roxadus.a

关键词： Hypoxia-inducible factor-2α Bone marrow niche Bone mes.nchymal s.em cells Os.eoporos.s Os.eogenic/adipogenic differentiation Mechanis.ic target of rapamycin s.gnaling pathway

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