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Mesoporous TS-1 Nanocrystals as Low Cost and High Perfor-mance Catalysts for Epoxidation of Styrene

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Chinese Journal of Chemistry 2017年第5期35卷 577-580页

作者： Tian-lu cui Xin-Hao Li Jie-Sheng Chen School of Chemistry and Chemical Engineering Shanghai Jiao Tong University Shanghai 200240 China

Mesoporous TS-1 nanocrystals were facilely synthesized without involving additional templates. The usage of inorganic silicon source, less structure-directing agent and high yields of nearly 100% made this template-free strategy suitable for large-scale synthesis with low cost. Furthermore, the as synthesized TS-1 exhibited comparable epoxidation performance than those obtained by other methods.

关键词： TS-1 mesoporous nanocrystal low cost epoxidation

Novel Synthesis of 2-Amino-3-ethoxycarbonyl Benzopyrans with Onium Salt as Soluble Support

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Chemical Research in Chinese Universities 2011年第3期27卷 435-440页

作者： ZHANG Li lu cui-fen YANG Gui-chun CHEN Zu-xing Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules. Faculty of Chemistry and Chemical Engineering Hubei University Wuhan 430062 P. R. China

Task specific onium salt has been presented as soluble support in the synthesis of benzopyrans in this paper. This method allows for results by far superior to those reported other soluble supports and allows for very... 详细信息

关键词： Onium salt Support Benzopyran

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医院专项区域暖通空调系统设计要点探讨

洁净与空调技术 2024年第2期 63-67页

作者：杨绘敏张金丹卢翠山东省建筑设计研究院有限公司麦克维尔中央空调有限公司济南分公司

介绍了专项区域各科室HVAC系统设计要点,主要是冷热源及加湿器的形式的选择原则,对于不同区域需要注意的事项,像DSA区域送风天花的设计、设备间温度处理;中心供应室设备夹层温度过高、环氧乙烷气体排放的处理;B2生物安全柜的补风问题;... 详细信息

介绍了专项区域各科室HVAC系统设计要点,主要是冷热源及加湿器的形式的选择原则,对于不同区域需要注意的事项,像DSA区域送风天花的设计、设备间温度处理;中心供应室设备夹层温度过高、环氧乙烷气体排放的处理;B2生物安全柜的补风问题;静脉配置中心的抗生素配置中心及抗肿瘤配置中心排风问题;病理科室内空气处理、排风处理;手术部的特殊手术室设计要点;监护病房及产科空气处理机组的选择等问题,以具体工程项目为例,给出了具体的解决方案。

关键词：专项区域空调系统设计要点直流式全新风空调系统一次回风空调系统

骨巨细胞瘤术后软组织复发31例临床特点分析

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中国骨与关节杂志 2024年第5期13卷 325-330页

作者：孙扬崔路宽金韬刘巍峰首都医科大学附属北京积水潭医院骨肿瘤科北京100035 沧州中西医结合医院骨与软组织肿瘤科河北省061000

目的明确骨巨细胞瘤(giant cell tumor of bone,GCTB)术后软组织复发情况,提高对GCTB术后软组织复发的认识。方法检索2003年1月至2022年12月,北京积水潭医院骨肿瘤科数据库GCTB术后复发患者筛选软组织复发患者。记录年龄、性别、原始病... 详细信息

目的明确骨巨细胞瘤(giant cell tumor of bone,GCTB)术后软组织复发情况,提高对GCTB术后软组织复发的认识。方法检索2003年1月至2022年12月,北京积水潭医院骨肿瘤科数据库GCTB术后复发患者筛选软组织复发患者。记录年龄、性别、原始病变部位及Campanacci分级、初次手术至软组织复发时间、复发次数、随访时间、末次随访时MSTS评分及并发症情况。结果共纳入GCTB术后软组织复发患者31例,男/女∶10/21例,软组织复发占GCTB术后复发的5.73%;年龄16~57岁,平均(28.52±9.93)岁。原始发病部位中位于腓骨近端、尺骨远端各4例,股骨近端、胫骨近端各3例,股骨远端6例,桡骨远端8例,第一掌骨、第一跖骨及髌骨各1例;初次手术时Campanacci分级:Ⅰ级2例,Ⅱ级9例,Ⅲ级20例;初次术后至软组织复发时间2~127个月,平均(23.23±26.12)个月;初次术后复发1次12例,2次12例,3次7例,复发2次及以上者占61.3%;因多发转移、肺转移死亡、行髋关节离断各1例;最终MSTS评分14~30分,平均(26.62±4.21)分。结论虽然GCTB术后软组织复发少见,但易出现多次复发并可能导致截肢或死亡等严重后果,应引起临床足够重视。

关键词：骨巨细胞瘤软组织肿瘤肿瘤复发局部再手术超声检查多普勒彩色体层摄影术 X线计算机磁共振成像

Development of genipin crosslinked gelatin matrices on surface interaction: Enhancing the biocompatibility by attenuating sterile inflammation

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Chinese Journal of Chemical Engineering 2021年第10期34卷 205-215页

作者： Qiang-Song Wang Gui-Fang Wang Hai-Yun Zhang Fa-Quan Zhao Yuan-lu cui Tianjin Key Laboratory of Biomedical Materials Institute of Biomedical EngineeringChinese Academy of Medical Science&Peking Union Medical CollegeTianjin 300192China State Key Laboratory of Component-based Chinese Medicine Research Center of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin 301617China

The inflammation can be stimulated by the surgical implantation and biomaterial presence through the foreign body via *** play a key role in the interaction of host tissue to implant *** present study,the immuno-inflammatory responses of genipin crosslinked gelatin matrices(GCGM)to macrophages in vitro and the host tissue surfaces in rats were *** results showed that the mechanical properties,swelling and degradation of gelatin matrices were improved by the crosslinking of genipin at physiological *** macrophage on the surface of GCGM could avoid to be *** interaction of macrophage and GCGM suggested that GCGM could reduce the inflammatory response with downregulating the production and m RNA expression of pro-inflammatory *** anti-inflammatory effect of GCGM was demonstrated to be related to inhibit nuclear factor kappa-B(NF-κB)signaling ***,gelatin matrices crosslinked with genipin could decrease the acute and chronic inflammatory response interacting with host tissue surfaces to enhance the biocompatibility in *** results showed that GCGM could avoid to active macrophages and were endowed with anti-inflammatory properties,suggesting the significant potential for clinical success with the development of immunomodulatory biomaterials.

关键词： Genipin Gelatin matrices Anti-inflammation Biocompatibility NF-κB

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生乳中脂多糖的来源及其影响因素

中国奶牛 2024年第8期 41-45页

作者：陆松翠陈美庆张养东中国农业科学院北京畜牧兽医研究所/农业农村部奶及奶制品质量安全控制重点实验室北京100193

脂多糖(LPS)是革兰氏阴性菌外膜的重要组成成分,在细胞分裂、外膜囊泡脱落或细菌细胞死亡的过程中,LPS会被释放到周围的介质中,也被称为内毒素。本文全面阐述了乳中LPS的来源及其相关影响因素,以期为后续对乳中LPS的相关研究及防控提供... 详细信息

脂多糖(LPS)是革兰氏阴性菌外膜的重要组成成分,在细胞分裂、外膜囊泡脱落或细菌细胞死亡的过程中,LPS会被释放到周围的介质中,也被称为内毒素。本文全面阐述了乳中LPS的来源及其相关影响因素,以期为后续对乳中LPS的相关研究及防控提供理论参考。

关键词：脂多糖生乳来源影响因素

日间病房开展内镜逆行胰胆管造影的可行性和安全性分析

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中国实用外科杂志 2024年第4期44卷 473-476页

作者：陈俊秦璐翠黄帅王贵阳姚俊发王辉李可为吴文广刘颖斌上海交通大学医学院附属仁济医院胆胰外科上海200127 上海交通大学医学院附属新华医院内镜中心上海200092

目的探讨日间病房开展内镜逆行胰胆管造影(ERCP)的安全性和可行性。方法回顾性分析2020年6月至2023年7月上海交通大学医学院附属仁济医院日间病房常规接受ERCP治疗的3555例病人的临床资料。分析病人的基本资料、手术情况、延迟出院和二... 详细信息

目的探讨日间病房开展内镜逆行胰胆管造影(ERCP)的安全性和可行性。方法回顾性分析2020年6月至2023年7月上海交通大学医学院附属仁济医院日间病房常规接受ERCP治疗的3555例病人的临床资料。分析病人的基本资料、手术情况、延迟出院和二次入院原因,比较住院时间>48 h(延迟出院)与住院时间≤48 h病人的临床资料。结果3538例(99.5%)病人ERCP手术成功,手术时间为20(5~124)min,总住院时间为(37.9±19.9)h,108例(3%)术后发生并发症。3136例(88.2%)病人在48 h内顺利出院,419例(11.8%)延迟出院。在延迟出院病人中,术前胆源性胰腺炎185例,术后胰腺炎70例,消化道出血3例,十二指肠穿孔2例,单纯腹痛或呕吐84例,发热75例。1周内二次入院20例(0.6%)。延迟出院病人并发症发生率和住院费用高于住院时间≤48 h病人(P0.05)。结论对于日间ERCP适应证,除中重度胆源性胰腺炎病人外,无需考虑病种、年龄、性别及合并症等因素,且团队分工协作是确保日间ERCP顺利开展的基础。

关键词：内镜逆行胰胆管造影日间病房延迟出院

Experimental investigation of spectral evolution in flash radiation by hypervelocity impact on aluminum plates

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Defence Technology（防务技术） 2024年第7期37卷 96-110页

作者： Xing Chen Yonggang lu Zhiwen Li Zhonghua cui Institute of Systems Engineering China Academy of Engineering PhysicsMianyang 621900SichuanChina Chongqing Qianwei Technology Group Co. LtdChongqing 401121China

In this study,a series of hypervelocity impact tests were carried out based on a two-stage light gas gun,and the sequence spectrum and radiation evolution data of the impact products under different impact conditions were *** diameter of the projectile is 3-5 mm,the impact velocity is 3.13-6.58 km/s,and the chamber pressure is 0.56-990 *** spectrum of ejected debris cloud in the 250-310 nm band were obtained using a transient spectral measurement system and a multi-channel radiometer measurement *** test results reveal that the flash radiation intensity increases as a power function with the kinetic energy of the ***,the peak value of the line spectrum decreases as the chamber vacuum degree increases,while the radiation width gradually *** line spectrum in the spectral characterization curve corresponds to the ejected debris clouds splitting phase,which does not produce significant line spectrum during material fragmentation and is dominated by the continuum spectrum produced by blackbody *** will appear one or three characteristic peaks in the flash radiation time curve,the first and second peaks correspond to the penetration phase and the third peak corresponds to the expansion phase of the ejected debris clouds on the time scale,the first and second peaks are more sensitive to the chamber vacuum degree,and when the pressure is higher than 99 Pa,the first and second characteristic peaks will *** radiant heat attenuation of the flash under different impact conditions is significantly different,the attenuation exponent has a power function relationship with the impact velocity and the chamber vacuum degree,while the attenuation exponent has a linear relationship with the diameter of the projectile,the specific expression of the attenuation exponent is obtained by *** findings from this research can serve as a valuable reference for remote diagnostic technologies based on flash radiation characte

关键词： Hypervelocity impact Flash radiation Evolution Spectral characteristics Damage evaluation

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探究焦亡与原发性干燥综合征的关系

临床口腔医学杂志 2024年第3期40卷 136-140页

作者：陆晓翠侯辰兴程波武汉大学中南医院口腔科湖北武汉430071

目的:探究焦亡与原发性干燥综合征的关系,方法:干扰素-γ(interferon-γ,IFN-γ)处理A253细胞系,通过CCK-8、细胞活死染色检测细胞活力,实时定量荧光PCR(qRT-PCR)检测焦亡相关指标mRNA水平,免疫荧光检测焦亡相关蛋白水平,免疫组织化学... 详细信息

目的:探究焦亡与原发性干燥综合征的关系,方法:干扰素-γ(interferon-γ,IFN-γ)处理A253细胞系,通过CCK-8、细胞活死染色检测细胞活力,实时定量荧光PCR(qRT-PCR)检测焦亡相关指标mRNA水平,免疫荧光检测焦亡相关蛋白水平,免疫组织化学染色检测人组织标本中焦亡相关蛋白水平,再用焦亡抑制剂Vx765分别处理受IFN-γ刺激和经二甲基亚砜(Dimethyl sulfoxide,DMSO)处理的A253细胞,检测对应组别的细胞活力和相关因子的mRNA水平。结果:IFN-γ处理组细胞活力明显下降,焦亡相关指标的mRNA和蛋白水平均升高,人唇腺组织标本中的焦亡相关通路蛋白表达也升高,且经Vx765处理后,IFN-γ组细胞活力增加,且焦亡相关炎性因子的mRNA水平降低。结论:原发性干燥综合征在发生的同时可能伴随着焦亡。

关键词：焦亡原发性干燥综合征炎症