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Developing biophilic inter.ediate spaces for.Ar.tic housing:Optimizing the ther.al,visual,and ener.y per.or.ance

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Building Simulation 2024年第6期17卷 857-875页

作者： Tar.an Abazar. Andr.Potvin louis Gosselin Claude MH Demer. Gr.P(Gr.upe de r.cher.he en ambiance physiques) School of ArchitectureLaval UniversityQuébecCanada Depar.ment of Mechanical Engineer.ng Faculty of Science and EngineeringLaval UniversityQuébecCanada

Connecting occupants to the outdoor.envir.nment and incor.or.ting biophilic design pr.nciples ar. challenging in extr.me Ar.tic climatic *** Ar.tic housing models do not pr.vide efficient ther.al and daylight tr.nsitions which ar. essential for.the well-being and cultur.l needs of their.*** addr.ss these challenges,this r.sear.h develops fr.e-r.nning biophilic inter.ediate spaces,integr.ted into an existing Ar.tic housing *** simulation methods ar. employed to optimize the pr.mar. and secondar. ar.hitectur.l design var.ables for.26 case studies of inter.ediate *** var.ables include volume,tr.nspar.ncy r.tio,and *** var.ables include mater.als and physical ***,Daylight Factor.Autonomy,and Ener.y Use ar. evaluated as per.or.ance *** r.veal that fr.e-r.nning inter.ediate spaces with 6 meter. depth and a tr.nspar.ncy r.tio above 50%pr.vide efficient indoor.outdoor.tr.nsitions r.gar.ing ther.al,visual,and ener.y *** ar.hitectur.l configur.tions contr.bute to an appr.ximately 5%r.duction in ener.y consumption within the housing unit compar.d to the *** side windows pr.vents the r.sk of over.eating dur.ng the summer.by r.ducing the aver.ge indoor.temper.tur. of inter.ediate spaces by 7°C but incr.ases the over.ll ener.y *** a potential alter.ative to double-glazing,polycar.onate sheets enable efficient ther.al per.or.ance by incr.asing the aver.ge indoor.temper.tur. of inter.ediate spaces by appr.ximately 15°C dur.ng the cold Ar.tic *** polycar.onate sheets r.sults in a 16.6%r.duction in ener.y consumption compar.d to using double-glazing mater.al in inter.ediate space,and a 26%r.duction fr.m the *** outcomes contr.bute to efficient indoor.outdoor.connections and ener.y efficiency in Ar.tic housing.

关键词： Ar.tic housing inter.ediate spaces biophilic design positive ther.al tr.nsitions daylight availability ener.y efficiency

Scanning tr.nsmission electr.n micr.scopy and atom pr.be tomogr.phy analysis of non-stoichiometr. long-per.od-stacking-or.er.d str.ctur.s in Mg-Ni-Y/Sm alloys

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Jour.al of Magnesium and Alloys 2024年第3期12卷 954-965页

作者： Yimeng Chen Manuel Legr.e Jean-louis Bobet Alexander.Kvit CAMECA Instr.ments Inc MadisonWI 53711USA ICMCB Universitéde BordeauxPessacCEDEX 33608France NIAC&Mater.als Science Depar.ment University of WisconsinMadisonWI 53706USA

The long-per.od-stacking-or.er.d(LPSO)str.ctur. affects the mechanical,cor.osion and hydr.lysis pr.per.ies of Mg *** cur.ent wor. employs high angle annular.dar. field-scanning tr.nsmission electr.n micr.scopy(HAADF-STEM)and atom pr.be tomogr.phy(APT)to investigate the str.ctur.l and local chemical infor.ation of LPSO phases for.ed in Mg-Ni-Y/Sm ter.ar. alloys after.extended isother.al *** on the alloying elements and their.concentr.tions,Mg-Ni-Y/Sm develops a two-phase LPSO+α-Mg str.ctur. in which the LPSO phase contains defects,hybr.d LPSO str.ctur.,and Mg ***-STEM and APT indicate non-stoichiometr.c LPSO with incomplete Ni_(6)(Y/Sm)_(8) *** addition,the APT quantitatively deter.ines the local composition of LPSO and confir.s the pr.sence of Ni within the Mg bonding *** r.sults pr.vide insight into a better.under.tanding of the str.ctur. and hydr.lysis pr.per.ies of LPSO-Mg alloys.

关键词： Magnesium alloys Long-r.nge or.er.ng Atom pr.be tomogr.phy(APT) STEM HAADF Hydr.lysis pr.per.ies.

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Spatial analysis of the osteoar.hr.tis micr.envir.nment: techniques, insights, and applications

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Bone r.sear.h 2024年第1期12卷 1-19页

作者： Xiwei Fan Antonia r.jia Sun r.uben S.E.Young Isaac O.Afar. Br.tt r.Hamilton louis Jun Ye Ong r.ss Cr.wfor. Indir. Pr.sadam Centr. for.Biomedical Technologies Queensland University of TechnologyBrisbaneQLDAustralia School of Mechanical Medical&Process EngineeringQueensland University of TechnologyBrisbaneQLDAustralia Centr.l Analytical r.sear.h Facility Queensland University of TechnologyBrisbaneQLDAustralia Molecular.Hor.zons University of WollongongWollongongNSWAustralia Depar.ment of Technical Physics University of Eastern FinlandKuopioFinland School of Electr.cal Engineer.ng and Computer.Science Faculty of EngineeringArchitecture and Information TechnologyUniversity of QueenslandBrisbaneQLDAustralia Centr. for.Micr.scopy and Micr.analysis University of QueenslandBrisbaneQLDAustralia The Pr.nce Char.es Hospital BrisbaneQLDAustralia

Osteoar.hr.tis(OA)is a debilitating degener.tive disease affecting multiple joint tissues,including car.ilage,bone,synovium,and adipose *** pr.sents diver.e clinical phenotypes and distinct molecular.endotypes,including inflammator.,metabolic,mechanical,genetic,and synovial ***,innovative technologies ar. needed to suppor. the development of effective diagnostic and pr.cision ther.peutic *** analysis of bulk OA tissue extr.cts has limitations due to technical constr.ints,causing challenges in the differ.ntiation between var.ous physiological and pathological phenotypes in joint *** issue has led to standar.ization difficulties and hinder.d the success of clinical *** insights into the spatial var.ations of the cellular.and molecular.str.ctur.s in OA tissues,encompassing DNA,r.A,metabolites,and pr.teins,as well as their.chemical pr.per.ies,elemental composition,and mechanical attr.butes,can contr.bute to a mor. compr.hensive under.tanding of the disease *** r.solved biology enables biologists to investigate cells within the context of their.tissue micr.envir.nment,pr.viding a mor. holistic view of cellular.*** advances in innovative spatial biology techniques now allow intact tissue sections to be examined using var.ous-omics lenses,such as genomics,tr.nscr.ptomics,pr.teomics,and metabolomics,with spatial *** fusion of appr.aches pr.vides r.sear.her. with cr.tical insights into the molecular.composition and functions of the cells and tissues at pr.cise spatial ***,advanced imaging techniques,including high-r.solution micr.scopy,hyper.pectr.l imaging,and mass spectr.metr. imaging,enable the visualization and analysis of the spatial distr.bution of biomolecules,cells,and *** these molecular.imaging outputs to conventional tissue histology can facilitate a mor. compr.hensive char.cter.zation of disease *** r.view summar.zes the r.c

关键词： insight Spatial enable

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Near.st Neighbor.Sampling of Point Sets Using r.ys

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1131-1174页

作者： Liangchen Liu louis Ly Colin B.Macdonald r.char. Tsai Depar.ment of Mathematics The University of Texas at Austin2515 SpeedwayAustinTX 78712USA Oden Institute for.Computational Engineer.ng and Sciences The University of Texas at Austin201 E24th StAustinTX 78712USA Depar.ment of Mathematics University of British Columbia1984 Mathematics RdVancouverBCV6T1Z2Canada

We pr.pose a new fr.mewor. for.the sampling,compr.ssion,and analysis of distr.butions of point sets and other.geometr.c objects embedded in Euclidean *** appr.ach involves constr.cting a tensor.called the r.ySense sketch,which captur.s near.st neighbor. fr.m the under.ying geometr. of points along a set of *** explor. var.ous oper.tions that can be per.or.ed on the r.ySense sketch,leading to differ.nt pr.per.ies and potential *** infor.ation about the data set can be extr.cted fr.m the sketch,independent of the r.y *** integr.ls on point sets can be efficiently computed using the *** also pr.sent sever.l examples illustr.ting applications of the pr.posed str.tegy in pr.ctical scenar.os.

关键词： Point clouds Sampling Classification r.gistr.tion Deep lear.ing Vor.noi cell analysis

Effects of the concentr.tion and natur. of total dissolved solids in dr.nking water.on feed intake, nutr.ent digestion, ener.y balance,methane emission, r.minal fer.entation, and blood constituents in differ.nt br.eds of young goats and hair.sheep

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Animal Nutr.tion 2024年第1期16卷 84-95页

作者： Amlan Kumar.Patr. Luana Paula dos Santos r.beir. Hir.t Yir.a Adekayode O.Sonibar. Ahmed r.Askar.Ali H.Hussein r.szar. Puchala Ar.hur.louis Goetsch Amer.can Institute for.Goat r.sear.h Langston University Animal and Poultr. Nutr.tion Depar.ment Desert Research Center Agr.cultur. Food and Natural ResourcesEastern New Mexico University

Under.tanding how differ.nt livestock species and br.eds r.spond to consumption of br.ckish water.could impr.ve usage of this ***,Angor.,Boer.and Spanish goat doelings and Dor.er.Katahdin,and *** ewe lambs (6 animals per.animal type[AT];initial age=296±2.1 days)consuming water.with var.ing concentr.tions of miner.ls of a natur.l br.ckish water.sour.e (Br. and sodium chlor.de (NaCl;SL) wer. used to deter.ine effects on water.and feed intake,nutr.ent digestion,heat ener.y,methane emission,r.minal fluid conditions,and blood constituent *** wer. 6 simultaneous 6 (water.tr.atments[WT])×6 (AT) Latin squar.s with 3-wk *** WT wer. fr.sh (Fr.,Br.alone (100-Br.,a similar.total dissolved solids (TDS) concentr.tion as 100-Br.via NaCl addition to Fr.(100-SL),Br.with concentr.tions of all miner.ls incr.ased by appr.ximately 50%(150-Br.,a similar.TDS level as 150-Br.by NaCl addition to Fr.(150-SL),and a similar.150 TDS level achieved by addition of a 1:1 mixtur. of Br.miner.ls and NaCl to 100-Br.(150-Br.SL).Concentr.tions (mg/kg) in Br.wer. 4928 TDS,85.9 bicar.onate,224.9 calcium,1175 chlor.de,60.5 magnesium,4.59 potassium,1387sodium,1962 sulfate,and 8.3 bor.n,and TDS in other.WT wer. 209,5684,7508,8309,and 7319 mg/kg for.Fr.100-SL,150-Br.150-SL,and 150-Br.SL,*** wer. ver. few significant effects of WT or.AT×WT inter.ctions,although AT had numer.us *** intake was affected by AT (P=0.02)and WT (P=0.04),with gr.ater.water.intake for.150-SL than for.Fr.100-Br.100-SL,and *** matter.intake among AT was lowest (Pr.*** of or.anic matter.and neutr.l deter.ent fiber.and heat ener.y differ.d among AT (Pr.gen digestion and r.minal methane emission wer. similar.among *** aldoster.ne concentr.tion was higher.(Pr.Fr.than for.other.*** conclusion,all AT seemed r.silient to these WT r.gar.less of miner.l sour.e and concentr.tions,with TDS less than 8300 mg/kg,which did

关键词： Goats Hair.sheep Nutr.ent utilization r.minal fer.entation Salinity Water.quality

A spotlight on dosage and subject selection for.effective neur.pr.tection: explor.ng the centr.l r.le of mitochondr.a

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Neur.l r.gener.tion r.sear.h 2025年第4期20卷 1081-1082页

作者： John Mitr.fanis Jonathan Stone Michael r.Hamblin Pier.e Magistr.tti Alim-louis Benabid Glen Jeffer. Fonds Clinatec UniversitéGrenoble AlpesGrenobleFrance School of Medical Science University of SydneySydneyAustralia Faculty of Health Sciences University of JohannesburgJohannesburgSouth Africa King Abdullah Univer.ity of Science and Technology ThuwalSaudi Arabia Institute of Ophthalmology University College LondonLondonUK

Neur.ns ar. notor.ously vulner.ble cell *** the slightest change in their.inter.al and/or.exter.al envir.nments will cause much distr.ss and dysfunction,leading often to their.death.A r.nge of pathological conditions,including str.ke,head tr.uma,and neur.degener.tive disease,can gener.te str.ss in neur.ns,affecting their.sur.ival and pr.per.*** most neur.l pathologies,mitochondr.a become dysfunctional and this plays a pivotal r.le in the pr.cess of cell *** challenge over.the last few decades has been to develop effective inter.entions that impr.ve neur.nal homeostasis under.pathological *** inter.entions,often r.fer.ed to as disease-modifying or.neur.pr.tective,have,however.pr.ved fr.str.tingly elusive,at both pr.clinical and,in par.icular.clinical *** this per.pective,we highlight two factor. that we feel ar. key to the development of effective neur.pr.tective *** ar.:fir.tly,the choice of dose of inter.ention and method of application,and secondly,the selection of subjects,whether.they be patients or.the animal model.

关键词： pr.tective dosage distr.ss

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Shear.behavior.and off-fault damage of saw-cut smooth and tension-induced r.ugh joints in gr.nite

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Jour.al of r.ck Mechanics and Geotechnical Engineer.ng 2024年第4期16卷 1216-1230页

作者： Fanzhen Meng Feili Wang louis Ngai Yuen Wong Jie Song Muzi Li Chuanqing Zhang Liming Zhang College of Science Qingdao University of TechnologyQingdao266033China Depar.ment of Ear.h Sciences The University of Hong KongPokfulamHong KongChina State Key Labor.tor. of Geomechanics and Geotechnical Engineer.ng Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China Cooper.tive Innovation Center.of Engineer.ng Constr.ction and Safety Shandong Peninsula Blue Economic Zone Qingdao266033China

The damage of r.ck joints or.fr.ctur.s upon shear.includes the sur.ace damage occur.ing at the contact asper.ties and the damage beneath the shear.sur.ace within the host *** latter.is commonly known as off-fault damage and has been much less investigated than the sur.ace *** main contr.bution of this study is to compar. the r.sults of dir.ct shear.tests conducted on saw-cut planar.joints and tension-induced r.ugh gr.nite joints under.nor.al str.sses r.nging fr.m 1 MPa to 50 *** shear.induced off-fault damages ar. quantified and compar.d with the optical micr.scope *** r.sults clear.y show that the planar.joints slip stably under.all the nor.al str.sses except under.50 MPa,wher. some local fr.ctur.s and r.gular.stick-slip occur.towar.s the end of the *** post-peak str.ss dr.p and stick-slip occur.for.all the r.ugh *** r.sidual shear.str.ngth envelopes for.the r.ugh joints and the peak shear.str.ngth envelope for.the planar.joints almost *** r.ot mean squar.(r.S)of asper.ty height for.the r.ugh joints decr.ases while it incr.ases for.the planar.joint after.shear.and a lar.er.nor.al str.ss usually leads to a mor. significant decr.ase or.incr.ase in ***,the extent of off-fault damage(or.damage zone)incr.ases with nor.al str.ss for.both planar.and r.ugh joints,and it is r.str.cted to a ver. thin layer.with limited micr.-cr.cks beneath the planar.joint *** compar.son,the thickness of the damage zone for.the r.ugh joints is about an or.er.of magnitude lar.er.than that of the planar.joints,and the coalesced micr.-cr.cks ar. gener.lly inclined to the shear.dir.ction with acute *** findings obtained in this study contr.bute to a better.under.tanding on the fr.ctional behavior.and damage char.cter.stics of r.ck joints or.fr.ctur.s with differ.nt r.ughness.

关键词： Planar.joint r.ugh joint Shear.behavior Off-fault damage Micr.-cr.cks

Per.onalised car. of patients with str.ke in China: a challenge and an oppor.unity

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Str.ke & Vascular.Neur.logy 2016年第1期1卷 3-5页

作者： louis r.caplan Mar. Fisher Har.ar. Medical School BostonMassachusettsUSA Beth Isr.el Deaconess Medical Center BostonMassachusettsUSA

Inter.entional tr.atment of patients with str.ke should r.kindle a push for.per.onalised’*** 1988,mor. than a quar.er.of a centur. ago,one of us(Lr.)made a plea for.per.onalised car. in an editor.al‘What is wr.ng with ***’.1 At that time,the technological tools available to image the br.in and its vascular.supply wer. far.infer.or.to those available *** editor.al was focused on patients with tr.nsient ischaemic attacks(TIAs).

关键词： patients tr.nsient push

Simulation and Analysis of the Effects of Pr.ssur. and Temper.tur. on the Output Voltage of Pr.ton Exchange Membr.ne Fuel Cells

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Jour.al of Power.and Ener.y Engineer.ng 2024年第2期12卷 1-16页

作者： Kashangabuye Bahufite louis School of Automation Wuhan University of Technology Wuhan China

Pr.ton exchange membr.ne fuel cell has advantages of high ener.y conver.ion efficiency, high r.liability, no pollution, low oper.ting temper.tur. and r.pid star.-up. It has become an ideal method of hydr.gen ener.y utilization and is also ideally suited to be used as the main sour.e of ener.y for.automobiles. Cur.ently, it constitutes a r.sear.h hot spot in the field of new ener.y vehicles. Based on the wor.ing mechanism of pr.ton exchange membr.ne fuel cells and empir.cal models, a ter.inal voltage dynamic model, an open cir.uit voltage model and thr.e voltage loss models ar. established. Matlab/Simulink softwar. is utilized to simulate the model and per.or. analyses in r.sponse to the impact of oper.ting temper.tur. and pr.ssur. on its per.or.ance. To enhance the efficiency of the pr.ton exchange membr.ne fuel cell, the oper.ting temper.tur. should be incr.ased in the medium and low cur.ent density zones and the oper.ting pr.ssur. should be incr.ased in the high cur.ent density zone.

关键词： Hydr.gen Ener.y New Ener.y Vehicles Empir.cal Models Voltage Dynamic Model