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糖尿病大鼠主动脉环的血管反应性能取决于糖尿病病程及葡萄糖浓度

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Oncology and Translational Medicine 1994年第2期11卷 115-115页

作者： B.J.Heesen Y.Ido J.r.Williamson B.H.r.Wolffenbuttel 傅良武 Washington University St.louis USA 同济医科大学附属同济医院

本研究比较了链脲菌素性糖尿病大鼠短病程组(DS,9天,血糖27.0±5.2mM)、长病程组(DL,6周,血糖26.0±5.0mM)与非糖尿病对照组(C)大鼠的离体主动脉环在正常(5mM)和高浓度(30mM)葡萄糖中对苯肾上腺素(phe,100μM)和乙酰胆碱

关键词：糖尿病病程糖尿病大鼠葡萄糖右旋糖己糖主动脉环

血浆胰岛素和血糖对1型糖尿病患者心肌血流的影响

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世界核心医学期刊文摘（心脏病学分册） 2005年第11期1卷 48-49页

作者： Srinivasan M. Herrero P. McGill J. B. r. J. Gropler 张平 Cardiovascular Imaging Laboratory Mallinckrodt Institute of Radiology 510 South Kingshighway Boulevard St. LouisMO63110United States Dr.

OBJECTIVES: The objective of this study was to determine the impact of insulin and glucose on myocardial vasodilator function in patients with type 1 diabetes mellitus(T1DM). BACKGrOUND: The relative importance of plasma insulin and glucose levels on the abnormal vasodilator function observed in T1DM is unknown. METHODS: Twenty T1DM patients underwent positron emission tomography studies to measure myocardial blood flow(MBF)(in ml/g/min) at rest(MBFr) and during adenosine(MBFa), both under baseline metabolic conditions and then during either hyperinsuline-miceuglycemic clamp(HE)(n=10; 40±9 years, 8 female subjects, hemoglobin A1c HbA1c 7.8±1.1%) or hyperinsulinemic-hyperglycemic clamp(HH)(n=10; 44±12 years, 8 female subjects, hemoglobin A1c 7.7±0.6%). rESULTS: Both groups showed similar MBFr and MBFa under baseline metabolic conditions(p=NS). Compared with baseline conditions, MBFr increased in the HH group(preas it did not change in the HE group. Compared with baseline conditions, MBFa decreased in the HH group(proup. Myocardial perfusion reserve(MPr)(MBFa /MBFr) was similar between the HE and HH groups at baseline(p=NS). During clamp, MPr tended to decrease in the HH group(proup(p=NS) when compared with baseline conditions. However, during the clamp MPr was significantly lower in the HH group when compared with the HE group(prt term, hyperglycemia has a deleterious effect on myocardial vasodilator function, which outweighs the beneficial effect of hyperinsulinemia.

关键词：心肌血流血浆胰岛素血管舒张功能高胰岛素血症

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低剂量多巴酚丁胺组织标记MrI及三维应变分析可评价缺血性心肌病患者的心肌存活

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世界核心医学期刊文摘（心脏病学分册） 2007年第1期3卷 17-18页

作者： Bree D. Wollmuth J.r. Cupps B.P. M.K. Pasque 朱启明 Division of Cardiovascular Surgery Queeny Tower Barnes-Jewish Hospital One Barnes-Jewish Hospital Plaza St. Louis MO 63110 United States.Dr

背景:组织标记M rI及三维应变分析可以定量测定心肌收缩性。作者检验如下假说,即分别于静息及应用低剂量多巴酚丁胺时进行三维应变分析可用于评价缺血性心肌病(ICM)患者的存活和无活力心肌。方法和结果:分别在静息和使用低剂量多巴酚丁... 详细信息

背景:组织标记M rI及三维应变分析可以定量测定心肌收缩性。作者检验如下假说,即分别于静息及应用低剂量多巴酚丁胺时进行三维应变分析可用于评价缺血性心肌病(ICM)患者的存活和无活力心肌。方法和结果:分别在静息和使用低剂量多巴酚丁胺时,对16例健康志愿者和14例ICM患者行射频组织标记M rI。计算所有受试者在静息和使用多巴酚丁胺时的三维整体和局部周应变(Ecc)。将其结果与心肌存活的常规临床数据相比较。

关键词：多巴酚丁胺 MrI 缺血性心肌病应变分析临床数据存活心肌节段收缩性定量测定周应左心室

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Correction to:Arbovirus and seizures

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Acta Epileptologica 2020年第1期2卷 194-194页

作者： Mingrui Zheng Shichuo Li r.Edward Hogan Meihua Yang West China School of Basic Medicine and Forensic Medicine Sichuan UniversityChengdu 610041China. China Association Against Epilepsy(CAAE) BeijingChina. Department of Neurology Washington UniversitySt.LouisMO 63110-1093USA. Epilepsy Centre Department of NeurosurgeryXinqiao HospitalArmy Military Medical UniversityChongqing 400037China.

After publication of this article[1],it is noticed the article contains an error:the section below should be placed between the section headings of‘Pathogenesis’and‘Activated glia’on page *** with the brain JEV’s neurotropism is a relevant factor of its *** is not synonymous with neurovirulence,but they can be associated with each other in some *** JEV typically replicates before it spreads to local lymph *** the liver,heart,kidney and other organs the blood-brain barrier(Fig.2).To cross the barrier,JEV replicates in endothelial cells inflammatory cells that carry the virus(Fig.3).

关键词： JEV section barrier

Sex Differences in Delaying Family＂ Effects on Job and Life Satisfaction

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Psychology research 2011年第6期1卷 444-452页

作者： Joshua Doemer Joel T. Nadler Meghan r. Lowery Southern Illinois UniversityCarbondale Carbondale USA Southern Illinois UniversityEdwardsville Edwardsville UAS Psychological Associates St. Louis USA

Individuals in the workplace can have a difficult time advancing both career and family, and this remains especially true for women. The decision to forego or delay a relationship in favor of advancement at work can have a detrimental impact on satisfaction. A national sample (N = 3504) was examined for sex differences in delaying relationships and the resulting impact on life and job satisfaction. An interaction was found between sex and delaying relationship commitments in relation to pay satisfaction. Men who had not delayed committing to a relationship were significantly more satisfied with pay than those who delayed. However, women did not show this difference. Men and women who delayed a relationship displayed significantly lower levels of life satisfaction. Women also reported lower earnings and more family stress, but also reported higher levels of job satisfaction. Overall, delay of marriage and family can lead a decrease in pay satisfaction, life and family satisfaction and an increase in stress.

关键词：工作满意度性别差异家庭生活延缓精神压力工作场所延迟

Differential Etiology of Posttraumatic Stress Disorder with Conduct Disorder and Major Depression in Men

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Differential Etiology of Posttraumatic Stress Disorder with ...

利用CT血管成像对肾脏进行测量:与活体肾移植供者肾功能的相关性研究

北京论坛（2006）文明的和谐与共同繁荣—对人类文明方式的思考

作者： Karestan C.Koenen Mark W.Miller Andrew C.Heath Kathleen K.Bucholz Michael J.Lyons Seth A.Eisen William r.True Jack Goldberg Ming T.Tsuang Department of Society Human Developmentand HealthHarvard School of Public HealthBostonMA Department of Psychiatry Boston University School of Medicine Midwest Alcoholism research Center at Washington University Department of Psychiatry Washington University School of MedicineSt.LouisMO Department of Psychology Boston UniversityBostonMA Harvard Institute of Psychiatric Epidemiology and Genetics Department of EpidemiologyHarvard School of Public HealthBostonMA Department of Psychiatry Harvard Medical School at MassachusettsMental Health CenterBostonMA Department of Internal Medicine Washington University School of MedicineSt.LouisMO Department of Community Health St.Louis University School of Public HealthSt.LouisMO Seattle VA ErIC/Vietnam Era Twin registry SeattleWashington Department of Epidemiology University of WashingtonSeattleWashington University of California Medical School in San Diego San DiegoCA

Posttraumatic stress disorder(PTSD) is a notable public health *** is an extremely debilitating condition that can occur following exposure to a psychologically distressing event that is outside the range of usual human *** events that can trigger PTSD include violent personal assaults(*** and sexual abuse),natural or human-caused disasters(*** and terrorism bombing),accidents(*** traffic accidents and families of victims),or military *** etiology of PTSD is not clear, although exposure to a traumatic event constitutes a necessary,but not sufficient,*** is highly comorbid with major depression(MD) and conduct disorder(CD) in both epidemiologic and clinical *** of individuals who are at elevated risk for developing PTSD has important implications for public health disaster preparedness and prevention of *** examine the genetic and environmental architecture of the comorbidity of PTSD with MD and CD,we analyzed 6,744 middle aged male-male monozygotic and dizygotic twins from the Vietnam Era Twin registry maintained in the *** members of a pair were interviewed by telephone using the Diagnostic Interview Schedule for Diagnostic and Statistical Manual of Mental Disorders,Third Edition,revised(DSM-Ⅲ-r) in *** equation modeling was used to estimate additive genetic,shared environmental and nonshared environmental effects common and specific to PTSD,CD,and MD.A set of competing nested models were assessed by comparing the goodness-of-fit between the full model and the submodel using the chi-square test and *** found that genetic,shared environmental and nonshared environmental influences contributed to 19%(95%CI:11-26%),9%(95%CI:6-17%), and 70%(95%CI:64-77%) of the total variance in PTSD,*** genetic effects on PTSD overlapped with those on MD,while all shared environmental effects on PTSD overlapped with those on *** 3%and 8%of nonshared env

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国际医学放射学杂志 2012年第6期 588-589页

作者： M.Yano K.A.Hoffman A.Vijayan T.K.Pilgram V.r.Narra 郑晶晶 Mallinckrodt Institute of radiology Washington University/Barnes Jewish Hospital510 S Kingshighway BlvdCampus Box 8131St LouisMO 63110

摘要目的探讨CT血管成像(CTA)影像上测量供体肾脏大小的哪个参数与肾移植术前和术后的肾功能关系最密切。材料与方法伦理审查委员会批准了此项符合HIPAA的回顾性研究,且无需获得病人知情同意。在CTA影像上对111例进行活体肾移植术肾脏... 详细信息

摘要目的探讨CT血管成像(CTA)影像上测量供体肾脏大小的哪个参数与肾移植术前和术后的肾功能关系最密切。材料与方法伦理审查委员会批准了此项符合HIPAA的回顾性研究,且无需获得病人知情同意。在CTA影像上对111例进行活体肾移植术肾脏的长度、

关键词：肾脏长度肾功能肾移植术后活体血管成像供者 CT

Correction: Activation of rAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

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Signal Transduction and Targeted Therapy 2022年第5期7卷 1860-1860页

作者： Qi Zhang Bridget riley-Gillis Lina Han Yannan Jia Alessia Lodi Haijiao Zhang Saravanan Ganesan rongqing Pan Sergej N.Konoplev Shannon r.Sweeney Jeremy A.ryan Yulia Jitkova Kenneth Dunner Jr Shaun E.Grosskurth Priyanka Vijay Sujana Ghosh Charles Lu Wencai Ma Stephen Kurtz Vivian r.ruvolo Helen Ma Connie C.Weng Cassandra L.ramage Natalia Baran Ce Shi Tianyu Cai richard Eric Davis Venkata L.Battula Yingchang Mi Jing Wang Courtney D.DiNardo Michael Andreeff Jeffery W.Tyner Aaron Schimmer Anthony Letai rose Ann Padua Carlos E.Bueso-ramos Stefano Tiziani Joel Leverson relja Popovic Marina Konopleva Department of Leukemia The University of Texas MD Anderson Cancer Center Houston TX USA Institute of Hematology Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin China Department of Hematology The First Hospital Affiliated Harbin Medical University Harbin China AbbVie Inc. North Chicago IL USA Department of Nutritional Sciences Department of Pediatrics Department of Oncology Dell Medical School The University of Texas at Austin Austin TX 78712 USA Department of Cell Developmental & Cancer Biology Division of Hematology & Medical Oncology Knight Cancer Institute Oregon Health & Science University Portland OR USA Université de Paris Institut de la Recherche Saint-Louis (IRSL) Inserm Unit 1131 Paris France Dana-Farber Cancer Institute Boston MA USA Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston TX USA Princess Margaret Cancer Center Toronto ON Canada High resolution Electron Microscopy Facility The University of Texas MD Anderson Cancer Center Houston TX USA Department of Bioinformatics & Computational Biology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Lymphoma & Myeloma research The University of Texas MD Anderson Cancer Center Houston TX USA

Correction to:Signal Transduction and Targeted Therapy(2022)7:1–13,https://***/10.1038/s41392-021-00870-3 In the original version of this article,given name of 4th author Yannan Jia was incorrectly published as Yanan *** original article has been *** Access This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use,sharing,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source.

关键词： myeloid Therapy resistance

DWI预测治疗前乳腺癌病人对新辅助化疗的反应性

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国际医学放射学杂志 2013年第6期 593-594页

作者： r.richard I.Thomassin M.Chapellier A.Scemama P.de Cremoux M.Varna 时代刘倩 radiology Department Saint-Louis Hospital1 avenue Claude Vellefaux75010 Paris France

摘要目的评估表观扩散系数(ADC)值对不同类型乳腺癌病人采用新辅助化疗后反应性的预测能力。材料与方法该回顾性研究已得到相应机构委员会的批准。研究人群为

关键词：乳腺癌扩散磁共振成像新辅助化疗预后肿瘤的组织学类型