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Irvingia Fat Ageing: Study of Chemical Characteristics Related to MIR Spectroscopy

Spectral Analysis Review 2023年第1期7卷 1-12页

作者： Aristide H. W. Nakavoua Gadet M. Dzondo Aubin N. Loumouamou louis matos Gilles Figueredo Laboratory of Chemistry of Natural Substances (IRSEN) Brazzaville Congo Marien Ngouabi University National Polytechnic High School (ENSP) Laboratory for the Valorisation of Agri-Resources Brazzaville Congo Laboratory of Industrial Process Engineering UNESCO Chair-ENSP Marien Ngouabi University Brazzaville People’s Republic of Congo LEXVA Analytical 460 Montant Street 63540 Romagnat French or Henri Mondor Street Biopole Clermont Limagne 63360 Saint Beauzire French

The Irvingia gabonensis kernels, which have been extensively studied for their numerous virtues, including the ability to act against the accumulation of fats in the body[1], contain an oil. The aging of this oil under two different conditions of conservation was the subject of our work. One of the results was an increase in the content of long-chain carbonaceous fatty acids during aging for 11 months of storage at low temperature (6℃) and at 30℃. This behavior does not find a concordant explanation by the comparative analysis of the chemical indices. Hence, there is the need to use the Medium Infra-Red spectroscopy (MIR) which allowed to clarify the information of the saponification index, to justify the weakness of the formation of peroxides in the case of the conservation at 30℃ and to confirm the information given by the peroxide index. It also allowed to understand the formation of the long carbon chains by the “cis-trans” isomerization and the homolytic cuts which intervene within the matrix of the fat by the analysis of the number of -CH2 and -CH3 groups in the two conditions of conservation. This study reveals that the rapid solidification of Irvingia gabonensis oil at room temperature[2] is an advantage for its preservation at room temperature but a great weakness when the fat is stored at low temperature.

关键词： Ageing Irvingia gabonensis MIR Cis-Trans Isomerism

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Manufacturing of Composite Pasta by a Mixing Plan

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Food and Nutrition Sciences 2021年第2期12卷 206-221页

作者： Laurette Brigelia Nkeletela Fanny Belgonde Ganongo-Po André Kimbonguila Salomé Itoua Guenonie louis matos Jeremy Petit Joel Scher Jean Mathurin Nzikou Engineering Laboratories of Industrial Processes ENSP Marien Ngouabi University Brazzaville Republic of the Congo University of Lorraine LIBio (Laboratory of Biomolecules Engineering) Nancy France Institute for Medicinal Research Center for Research and Study Djibouti Republic of Djibouti

The partial replacement of durum wheat semolina with local flours such as soybeans and yam reduces the dependence of durum wheat semolina for the production of pasta. The main objective of this study is to develop yam flour (A) from Dioscorea alata in the manufacture of pasta made with durum wheat semolina (B) and soy flour (C) (raw materials). The methodology adopted consists first of all in the characterization of yam, soybean and durum wheat semolina. An experimental design was developed to bring out the balanced mixing plan in well-defined proportions with ten (10) tests. Chemical and functional analyzes were carried out on the pastes obtained from these formulations. The functional properties allowed us to determine the optimal mixing plan using a mathematical model. The sensory properties of the optimal compound dough were estimated in comparison with the control doughs. The results on the chemical properties of raw materials A, B and C obtained on the water content vary from 10.29% to 12.29%;those of ashes vary from 0.91% to 5.74% and those of proteins vary from 3.24% to 20.17%. The results of the chemical and functional parameters of compound pasta gave very diverse values. We find that the water content, the ash content, the protein content and the acidity rate of the series of 10 tests are respectively from 6.60% to 14.97%, from 0.97% to 1.67%, from 7.15% to 12.10% and from 1.35% to 3.60%. Regarding the optimal cooking time for this s

关键词： Compound Pasta Chemical and Functional Parameters Optimization Sensory Test

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Evaluation of Some Secondary Metabolites and Determination of the Antioxidant Potential of Different Extracts from the Plant of <i>Pteridium aquilinum</i>

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American Journal of Analytical Chemistry 2021年第12期12卷 506-519页

作者： Arnaud W. G. Tamba Sompila Aimé B. Madiélé Mabika Nadia P. G. Pambou-Tobi Tsiba Gouollaly Jacques E. Moussounga Gloria L. L. Bissombolo N’simba Roniche Nguie louis matos National Institute for Research in Engineering Sciences Innovation and Technology Scientific City Brazzaville Congo Laboratory of Food and Medical Bioprocesses National Polytechnic School Marien Ngouabi University Brazzaville Congo National Polytechnic School Marien Ngouabi University Brazzaville Congo Plant and Life Chemistry Unit Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo National Institute for Research in Health Sciences Scientific City Brazzaville Congo Pole of Excellence in Food and Nutrition Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo

The present study aims to make an evaluation of some secondary metabolites and determination of the antioxidant potential of P. aquilinum plant extracts obtained by means of a simple and rapid TLC method. The latter revealed the presence of terpenes, sterols, steroids, flavonoids, polyphenols, saponins, sugars and amino acids. The evaluation of the potential antioxidant was assessed on phenolic and flavonoid compounds. These compounds’ dosages revealed different levels, but the highest antioxidant activity was found in the hydro-ethanol extract followed by the aqueous extract. Among the two families of evaluated antioxidants, phenolic compounds were found to be higher in the hydro-ethanolic extract (75.18 mgEAG/gMS), followed by the aqueous extract (66.78 mgEAG/gMS) and lower in the ethanolic extract (12.39 mgEAG/gMS). Whereas flavonoids, less significantly elevated, showed values of 2.58 mgECa/gMS for the hydro-ethanolic extract, 2.24 mgECa/gMS for the aqueous extract and 1.58 mgECa/gMS for the ethanolic extract. However, the antiradical activity was also evaluated. Contrary to the antioxidant activity, the most important antiradical activity was observed on the hydroethanolic extract with a rate of 3.61 mg/mL, then a weak activity on the aqueous and ethanolic extracts respectively 6.18 mg/mL and 15.81 mg/mL, then less important on the aqueous and hydro-ethanolic extracts respectively at levels of 6.18 mg/mL and 3.61 mg/mL.

关键词： Evaluation Extracts Secondary Metabolites Potential Antioxidant Pteridium aquilinum

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Angiotensin-Converting Enzyme(ACE)Inhibitors May Moderate COVID-19 Hyperinflammatory Response:An Observational Study with Deep Immunophenotyping

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Health Data Science 2022年第1期2022卷 1-14页

作者： Venkata R.Duvvuri Andrew Baumgartner Sevda Molani Patricia V.Hernandez Dan Yuan Ryan T.Roper Wanessa F.matos Max Robinson Yapeng Su Naeha Subramanian Jason D.Goldman James R.Heath Jennifer J.Hadlock Institute for Systems Biology SeattleWAUSA Department of Bioengineering University of WashingtonSeattleWAUSA Washington University St.LouisMOUSA Swedish Center for Research and Innovation Swedish Medical CenterSeattleWAUSA Providence St.Joseph Health RentonWAUSA Division of Allergy and Infectious Diseases University of WashingtonSeattleWAUSA.

Background:Angiotensin-converting enzyme inhibitors(ACEi)and angiotensin-II receptor blockers(ARB),the most commonly prescribed antihypertensive medications,counter renin-angiotensin-aldosterone system(RAAS)activation via induction of angiotensin-converting enzyme 2(ACE2)*** that ACE2 is the functional receptor for SARS-CoV-2 entry into host cells,the association of ACEi and ARB with COVID-19 outcomes needs thorough ***:We conducted retrospective analyses using both unmatched and propensity score(PS)-matched cohorts on electronic health records(EHRs)to assess the impact of RAAS inhibitors on the risk of receiving invasive mechanical ventilation(IMV)and 30-day mortality among hospitalized COVID-19 ***,we investigated the immune cell gene expression profiles of hospitalized COVID-19 patients with prior use of antihypertensive treatments from an observational prospective ***:The retrospective analysis revealed that there was no increased risk associated with either ACEi or ARB *** fact,the use of ACEi showed decreased risk for *** analyses using PS-matched cohorts suggested no significant relationship between RAAS inhibitors with a hospital stay and in-hospital mortality compared to non-RAAS medications and patients not on antihypertensive *** the analysis of gene expression profiles,we observed a noticeable up-regulation in the expression of 1L1R2(an anti-inflammatory receptor)and RETN(an immunosuppressive marker)genes in monocytes among prior users of ACE ***:Overall,the findings do not support the discontinuation of ACEi or ARB treatment and suggest that ACEi may moderate the COVID-19 hyperinflammatory response.

关键词： hypertensive inflammatory Angiotensin

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