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38例窒息复苏后新生儿出生3天内微量血糖测定及临床意义

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中国现代医药科技 2003年第4期3卷 5-6页

作者：郑瑜齐桂玲侯春梅刘炎洁杜桂兰赵瑛内蒙古呼和浩特铁路局中心医院儿科010010

目的探讨围产期窒息对新生儿血糖的影响。方法对1年内住院出生的38例窒息患儿生后72小时进行连续血糖测定。结果新生儿微量血糖平均值随日龄增加呈不断递升现象(经方差分析，f=10．46，P0．05)；剖宫产组低血糖发生率与对照组无明显... 详细信息

目的探讨围产期窒息对新生儿血糖的影响。方法对1年内住院出生的38例窒息患儿生后72小时进行连续血糖测定。结果新生儿微量血糖平均值随日龄增加呈不断递升现象(经方差分析，f=10．46，P0．05)；剖宫产组低血糖发生率与对照组无明显差异(P>0．05)，生后12小时、24小时窒息组血糖水平低于对照组且低血糖发生率高于对照组(P0．05)。不同日龄对照组与轻度窒息组比较，差异无显著性(P>0．05)，对照组与重度窒息组比较，有显著差异(P<0．01)，轻度窒息组与重度窒息组比较24小时有显著差异。结论窒息复苏后新生儿血糖平均值处于较低水平，且低血糖发生率明显高于正常新生儿，血糖监测对窒息新生儿，尤其是重度窒息、剖宫产患儿尤为重要。

关键词：新生儿窒息血糖神经系统诊断

Experimental Podophyllotoxin (Bajiaolian) Poisoning:——Ⅰ. Effects on the Nervous System

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Biomedical and Environmental Sciences 1992年第4期5卷 283-292页

作者： louis W.CHANG C.M.YANG C.f.CHEN J.f.DENG Departments of Pathology Pharmacology and Toxicology University of Arkansas for Medical Sciences Little RockThe Chang-Gung Medical College Kwai-sanNational Research Institute of Chinese MedicineThe Veteran General Hospital AR 72205TaipeiTaipeiTaipei Taiwan China

Bajiaolian, one of the species in the Mayapple family ( Podophyllum pelatum ), has been widely used as a traditional Chinese herbal medicine for the remedies of snake bites, general weakness, poisons, condyloma accuminata, lymphadenopathy, and certain tumors in China. In Western medicine, Podophyllum was first used medically as a laxative in the early 19th century. Since 1940, the resin of podophyllum has also been used topically for various skin lesions, such as warts and condyloma. Human poisonings have been reported.An animal model was established to investigate the neurotoxic effects of Bajiaolian. Podophyllotoxin, the major active ingredient in Podophyllum, was injected (ip) to young adult male rats at doses of 0, 5, 10, or 15 mg-kg-1 b.w.. The animals were sacrificed 72 h after injection.Neuronal changes were readily observable in animals treated with 10 or 15 mg-kg-1 of the toxin. Edematous changes of the anterior horn motoneurons were observed in the spinal cord. No neuronal necrosis was found. The type of neuronal swelling is believed to be only a transient change and would probably subside with time if no further assaults occur. More serious and perhaps longer term of changes were found in the dorsal ganglion neurons and the nerve fibers (axons) in the central and peripheral nervous system. Severe depletion of the Nissl substance (RNA/polyribosomes) was observed in the dorsal root ganglion neurons. Alterations in these sensory neurons would give rise to and correlate with the sensory disturbances experienced by the patients. Bodian staining also revealed a dose-related increase in the coarseness (thickness) of the nerve fibers (axons) in the cerebellum, cerebral cortex, brainstem, and spinal cord.This is the first scientific study showing the neurotoxicity of Bajiaolian, a commonly used Chinese herbal medicine. Toxicities on other organ systems by this drug certainly exist. Caution should be exercised in the dispensing and usa

关键词： Bajiaolian Effects on the Nervous System Experimental Podophyllotoxin Poisoning

HPLC法测定不同产地牛膝中β-蜕皮甾酮的含量

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亚太传统医药 2014年第1期10卷 30-31页

作者：梁洁唐春风覃爱环广西药用植物研究所广西南宁530023 广西万寿堂药业有限公司广西南宁530200

目的：比较分析不同产地牛膝中β-蜕皮甾酮的含量差异，以评价其质量。方法：采用HPLC法对不同产地的牛膝f3蜕皮甾酮含量进行测定。色谱柱为Kromasil C18（250mm×4．6mm，5μm）；流动相为乙腈：水（15：85）。结果：β-蜕皮甾酮在0．2... 详细信息

目的：比较分析不同产地牛膝中β-蜕皮甾酮的含量差异，以评价其质量。方法：采用HPLC法对不同产地的牛膝f3蜕皮甾酮含量进行测定。色谱柱为Kromasil C18（250mm×4．6mm，5μm）；流动相为乙腈：水（15：85）。结果：β-蜕皮甾酮在0．2064-2．58μg范围内线性关系良好（r=0．9992），平均回收率为99．34％。结论：不同产地的牛膝中β-蜕皮甾酮含量有别，但均达到药典要求。

关键词： HPLC 牛膝 β-蜕皮甾酮含量测定

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水稻新品种吉粳81选育报告

吉林农业科学 2004年第6期29卷 31-32页

作者：侯春香金成海王景余方秀琴吉林省农科院水稻研究所吉林公主岭136100

吉粳81是以一目惚／舞姬f8幼穗体细胞无性系变异后代筛选育成的优质米新品种。生育期145 d,属晚熟品种。抗低温冷害、抗霜、耐旱性较强。

关键词：选育报告水稻新品种育成晚熟品种耐旱性幼穗冷害体细胞无性系变异筛选后代

The structure of colloidal polyethylenimine-silica nanocomposite microparticles

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Particuology 2023年第5期76卷 86-100页

作者： Alexandra Semenova Luke W.Giles Mark louis P.Vidallon Bart follink Paul L.Brown Rico f.Tabor School of Chemistry Monash University19 Rainforest Walk.Clayton3800Australia Rio Tinto Bundoora Technical Development Centre1 Research AvenueBundoora3083Australia

Deposition of silica from an organosilane tetraethoxysilane(TEOS)onto parent polyethylenimine(PEI)microgel particles produces a novel PEI-silica nanocomposite,which possesses greater adsorption ca-pacity for copper ions than either parent *** study explores factors governing interactions of silica with the PEI matrix,along with structural features of resulting PEI-silica composite particles,to explain their properties and determine their application *** influence of initial TEOS/PEI mass ratio and the duration of silica deposition on the final silica content and distribution in the composite are studied.A comparative analysis of the structural architecture of chemically etched silica remnants,original PEI-silica composite particles and the parent PEI-microgel is carried out using X-ray photo-electron spectroscopy,small-angle X-ray scattering,and electron microscopy *** is found that silica sol nanoparticles are evenly distributed throughout the PEI-microgel framework and interlinked with it via electrostatic interactions,enabling a structural model of the PEI-silica nanocomposite to be *** chemical stability of resulting nanocomposite particles in parallel with the parent PEI-microgel is tested and shown to be robust for more than 100 days of storage in aqueous dispersions across a range of pH conditions,highlighting the application potential for these particles in copper capture.

关键词： Polyethylenimine Silica Organic-inorganic composite Nano-scale morphology Small angle X-ray scattering

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樱属景观植物资源分类研究

浙江林业科技 2017年第1期37卷 20-25页

作者：严春风徐梁赵绮袁冬明王新屯沙存龙浙江省宁波市鄞州区林业技术管理服务站浙江宁波315100 浙江省林业科学研究院浙江杭州310023

2014-2016年,调查了云南、广东等12个省的55个种或品种在引种地的表现,结合各地应用情况,在对樱花品种资源分类基础上,将花色、花期作为主要分类依据,按照《国际栽培植物命名法规》进行种质分类和整理。分为11个野生种或变种,44个品种;... 详细信息

2014-2016年,调查了云南、广东等12个省的55个种或品种在引种地的表现,结合各地应用情况,在对樱花品种资源分类基础上,将花色、花期作为主要分类依据,按照《国际栽培植物命名法规》进行种质分类和整理。分为11个野生种或变种,44个品种;根据花色可分为白色、淡粉、粉红、紫红、黄绿5种颜色;根据花期可分为元春、迎春、探春和惜春4个花期。

关键词：樱属分类花期花色检索表

帕金森病合并快速眼球运动睡眠行为障碍患者的客观睡眠结构及认知功能

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中华神经科杂志 2013年第10期46卷 651-654页

作者：沈赘毛成洁熊康平龚艳韩菲胡伟东黄隽英刘春风苏州大学附属第二医院神经内科 215004

目的评价帕金森病合并快速眼球运动睡眠行为障碍（RBD）患者的睡眠结构及认知功能，并探讨其睡眠结构与认知功能之间的相关性。方法本研究为横断面研究，以在我院睡眠中心进行睡眠监测的39例帕金森病合并RBD患者作为病例组，并以年龄、... 详细信息

目的评价帕金森病合并快速眼球运动睡眠行为障碍（RBD）患者的睡眠结构及认知功能，并探讨其睡眠结构与认知功能之间的相关性。方法本研究为横断面研究，以在我院睡眠中心进行睡眠监测的39例帕金森病合并RBD患者作为病例组，并以年龄、性别相匹配的21例原发性快速眼球运动睡眠行为障碍（iRBD）患者及37例不合并RBD的帕金森病患者作为对照组。所有患者均行整夜睡眠监测以定量睡眠相关参数，并且于监测当天使用蒙特利尔（MoCA）评估量表评估其认知功能。采用多重线性回归分析量表得分与睡眠结构之间的相关性。结果（1）帕金森病合并RBD患者的睡眠效率（60．9％±16．9％）、总睡眠时间[（329．7±96．5）min]、非快速眼动睡眠2期时间[（127．6±67．6）min]及快速眼动睡眠期时间[（45．3±33．2）min]较iRBD组的相应值[77．8％±16．9％以及（397．1±88．9）、（188．0±94．7）、（70．6±25．9）min]比较明显减少（均P〈0．05），较不合并RBD的PD组的相应值[61．3％±21．7％以及（324．9±134．6）、（132．6±65．6）、（47．1±31．9）min]减少，但差异均无统计学意义。3组的睡眠潜伏期、快速眼球运动睡眠潜伏期、非快速眼球运动睡眠1期，慢波睡眠比例、氧减指数、呼吸暂停低通气指数及周期性肢体运动指数比较差异均无统计学意义。（2）帕金森病合并RBD患者认知功能最差，其中视空间与执行功能得分[（3．8±1．1）分]较iRBD组[（4．4±0．7）分]比较差异有统计学意义（f=3．426，P〈0．05）。（3）多重线性回归显示帕金森病合并RBD患者的RBD病程、睡眠效率和非快速眼动睡眠2期与视空间与执行功能得分有相关性。结论帕金森病合并RBD患者的睡眠效率、总睡眠、非快速眼动睡眠2期及快速眼动睡眠期时间和认知功能均明显下降，认知功能的改变与睡眠结构的变化可能存在相关性。

关键词：帕金森病 REM睡眠行为障碍多道睡眠描记术认知

Phase coexistence properties of liquid mercury:a simulation study

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Rare Metals 2006年第5期25卷 567-571页

作者： Jean-louis Bretonnet Jean-Marc Bomont Laboratoire de Physique des Milieux Denses Université Paul Verlaine1bd F.D.Arago57078 MetzCedex 3France

The thermophysical properties of expanded liquid mercury have been investigated along the liquid-vapor coexistence curve by using Monte Carlo and Molecular Dynamic simulations. for the purpose, an empirical state dependent interatomic potential for the region of dense metallic liquid is used, while the state dependence is not necessary near the cliffcal point. In order to test the validity of this potential, we determine the surface layering and the sound velocity, two properties very sensitive to the choice of the potential. Our results are in quite good agreement with other theoretical results and to the experimental data available in the literature.

关键词： mercury simulation phase coexistence liquid state

Watt-level and spectrally flat mid-infrared supercontinuum in fluoroindate fibers

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Photonics Research 2018年第6期6卷 609-613页

作者： fRANCIS THEBERGE NANCY BERUBE SAMUEL POULAIN SOLENN COXIC louis-RAfAEL ROBICHAUD MARTIN BERNIER REAL VALLEE Defence R&D Canada Valcartier Centre Quebec G3J1X5 Canada Le Verre fluore Campus KerLann F-35170 Bruz Brittany France Center for Optics Photonics and Lasers (COPL) Universite Laval Quebec G1V0A6 Canada

We report on infrared supercontinuum （SC） generation in step-index fluoroindate-based fiber by using an all-fiber laser source. In comparison to widely used ZBLAN fibers for high-power mid-infrared （MIR） SC generation, fluoroindate fibers have multiphoton absorption edges at significandy longer wavelengths and can sustain similar intensities. Recent developments highlighted in the present study allowed the production of fluoroindate fibers with MIR background loss of 2 dB/km, which is similar to or even better than ZBLAN fibers. By using an all-fiber picosecond laser source based on an erbium amplifier followed by a thulium power amplifier, we demonstrate the generation of 1.0 W infrared SC spanning over 2.25 octaves from 1 μm to 5 μm. The generated MIR SC also exhibits high spectral flatness with a 6 dB spectral bandwidth from 1.91 μm to 4.77 μm and an average power two orders of magnitude greater than in previous demonstrations with a similar spectral distribution.

关键词： fiber optics infrared Nonlinear optics fibers Supercontinuum generation