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Renal Vein Thrombosis Suggestive of Extramembranous Glomerulonephritis Associated with Sjögren’s Syndrome (Case Report)

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Open Journal of Internal Medicine 2024年第2期14卷 181-187页

作者： Mariam El Galiou Mina Agrou Rihab Dkhissi loubna Benamar Naima Ouzeddoun Lamyae Rouass Tarik Bouattar Department of Nephrology Dialysis and Transplantation IbnSina University Hospital Mohamed V University Rabat Morocco Department of Pathological Anatomy IbnSina University Hospital Mohammed V University Rabat Morocco

Introduction: Glomerular damage during Gougerot-Sjgren syndrome is much rarer than interstitial damage, and is essentially extra-membranous and membrano-proliferative glomerulonephritis. Observation: We report the case of a 44-year-old woman with primary Sjgrens syndrome, confirmed by clinical dryness syndrome, positive anti-SSA and anti-SSB antibodies, and a salivary gland biopsy revealing grade 4 lymphocytic sialadenitis according to CHISHOLMs classification. Later, the patient developed nephrotic syndrome, along with hypertension. Renal function remained normal with a creatinine level of 9.3 mg/l, and hematuria was absent. Only antinuclear antibodies tested positive, while anti-PLA2R antibodies were negative. A renal biopsy was performed, which was complicated on the same day by hemodynamic instability with hematuria. Renal CT scan with contrast injection revealed a posterior perirenal hematoma without contrast extravasation. Additionally, bilateral renal vein thrombosis was incidentally discovered, suggesting extramembranous glomerulonephritis. The patients hemodynamic status stabilized after fluid resuscitation with isotonic saline solution (0.9%), without the need for blood transfusion. Renal biopsy confirmed extramembranous glomerulonephritis with interstitial fibrosis and minimal tubular atrophy. The initial etiological assessment was negative. The patient was started on oral corticosteroids, angiotensin-converting enzyme inhibitors, and therapeutic anticoagulation for renal vein thrombosis. The patients condition improved, with the disappearance of the syndrome and spontaneous regression of the hematoma. Discussion: The association of nephrotic syndrome and renal vein thrombosis primarily suggests glomerulopathy, in particular extra-membranous glomerulonephritis. Sjgrens syndrome can be associated with extra-membranous glomerulonephritis without being its direct cause. Like, it is possible that it is a cause of glomerulonephritis, essentially extra membrano

关键词： Sjögren’s Syndrome Extramembranous Glomerulonephritis Nephrotic Syndrome Anti-PLA2R Antibodies

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Prognostic Factors in Cardiorenal Syndrome Type 1: Retrospective Observational and Analytical Study

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World Journal of Cardiovascular Diseases 2024年第7期14卷 435-445页

作者： Mariam El Galiou Amal Zniber Hajar Fitah Naima Ouzeddoun Tarik Bouattar Nawal Doghmi Laila Lahlou loubna Benamar Nephrology-Dialysis-Renal Transplantation Department Ibn Sina University Hospital Mohamed V University Rabat Morocco Department of Cardiology B Ibn Sina University Hospital Mohamed V University Rabat Morocco Laboratory of Biostatistics Clinical Research and Epidemiology Department of Public Health Mohamed V University Rabat Morocco

Introduction: Type 1 cardiorenal syndrome (CRS 1) is characterized by acute impairment of cardiac function leading to acute renal dysfunction. CRS1 is present in 25% of patients admitted for heart failure. The objective of our study is to analyze the epidemiological, clinical, therapeutic profile and the risk and prognostic factors of these patients. Materials and Methods: We identified 120 patients with cardiorenal syndrome (CRS) over a one-year period to determine the prevalence and risk factors for developing CRS 1. We analyzed the clinical, biological, and evolutionary profiles of patients with CRS 1 and determined the risk factors for the occurrence of acute kidney injury (AKI) as well as the mortality factors in these patients. Résultats: The average age of our patients with CRS1 is 58 ± 9 years, with a sex ratio of 1.4. The average eGFR of our patients is 35 ± 6.5 ml/min/1.73m2. Diabetes was found in 17% of our patients and hypertension in 14%. The etiology of cardiac impairment is predominantly acute coronary syndrome (ACS), followed by rhythm disorders. Renally, all our patients have acute kidney injury (AKI), with 86% having functional acute renal failure and 14% having acute tubular necrosis. Therapeutically, 50% of our patients are on diuretics, 42% receive beta-blocker treatment, and RAAS blockers are used in 29% of cases. Renal replacement therapy (RRT) sessions were required in 13.8% of cases. In univariate analysis, male gender, tachyarrhythmia, and hypertension are associated with the early onset of acute kidney injury (AKI). The use of diuretics, anemia, and low left ventricular ejection fraction (LVEF) are linked to a higher risk of developing CRS 1 (p = 0.021, p = 0.037, p = 0.010 respectively). In multivariate analysis, advanced age is significantly associated with increased mortality risk in CRS 1 patients (p = 0.030), while beta-blocker use is considered a protective factor (p = 0.014). Conclusion: Our study identifies several key factors asso

关键词： Acute Kidney Injury Type 1 Cardiorenal Syndrome Acute Heart Failure Diuretics

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Primary Hyperoxaluria Type 1 in Adulthood: Case Series

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Open Journal of Nephrology 2024年第3期14卷 350-360页

作者： Sara El Maakoul Nada El Kadiri Nabil Hmaidouch Salma Belmokadem loubna Benamar Tarik Bouattar Naima Ouzeddoun Department of Nephrology Dialysis Renal Transplantation Ibn Sina University Hospital-Rabat Rabat Morocco Faculty of Medicine and Pharmacy Mohammed V University Rabat Morocco

Introduction: Primary hyperoxaluria type 1 (HP1) is a rare lithiasis with systemic involvement, due to the accumulation of calcium oxalate crystals. In the absence of therapeutic management, it progresses to end-stage chronic renal failure. The aim of this study is to describe and analyse the observations of our patients with HP1. Patients and methods: This is a retrospective study carried out between 2014 and 2023 in the Nephrology-Dialysis Transplant Department of the Ibn Sina University Hospital in Rabat. The clinical, paraclinical and evolutionary elements were taken from the patients’ medical records. Results: We collected 11 cases, with a mean age of 27 ± 8.5 years and a M/F sex ratio of 1.7. The diagnosis of HP1 was made on the basis of genetic analysis in 8 patients, morphological and spectro-photometric analysis of the calculus in one patient, biopsy of the graft in one patient and crystalluria and a family history of PH1 in one patient. Two patients died, and 8 patients were on chronic haemdialysis with systemic damage. Only one patient maintained a stable GFR at 60 ml/min. Conclusion: Early diagnosis combined with conservative treatment is the only way to limit the rapid progression of this disease. This requires awareness and collaboration between nephrologists, urologists and biologists within a specialised team.

关键词： Primary Hyperoxaluria Adulthood Kidney Disease

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Comparison between PI-DTC-SPWM and fuzzy logic for a sensorless asynchronous motor drive

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Protection and Control of Modern Power Systems 2021年第1期6卷 430-442页

作者： Soukaina El Daoudi loubna Lazrak Laboratory of Automatic Energy Conversion and MicroelectronicsFaculty of Sciences and TechnologySultan Moulay Slimane UniversityBeni MellalMorocco

Currently, asynchronous cage motors are among the most commonly requested machines accentuated by their extension to the field of electric vehicles. Therefore, the development of robust and sophisticated controls for this machine is of significant interest. Artificial intelligence control techniques, such as fuzzy logic, are at the forefront of recent research. However, their design becomes much more complicated for a motor via a multilevel inverter. The main purpose of this paper is to show that it is possible to achieve fuzzy logic control of a squirrel cage asynchronous motor supplied via the usual two-level inverter. This is achieved, by adopting a DTC strategy based on a sinusoidal PWM with multilevel inverter. It employs a feedback information estimator with dual structure between the sliding mode observer at low speed and the model reference adaptive system in sliding mode at high speed. For both installations, speed is regulated using a sliding mode controller.

关键词： Asynchronous motor Direct torque control Fuzzy logic control Model Reference Adaptive System Sliding mode control Sliding mode observer

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Secondary Hyperparathyroidism in Dialysis Patients: Short- and Long-Term Outcomes of Conservative Parathyroidectomy

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Open Journal of Nephrology（肾脏病） 2024年第2期 147页

作者： Imane Saidi Sara Elmaakoul Naima Ouzeddoun loubna Benamar

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Peritoneo-Vaginal Leaks in Peritoneal Dialysis: A Report of 3 Cases

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Open Journal of Nephrology（肾脏病） 2024年第2期 176页

作者： Mariam Jdidou Sara Elmakkoul Nabil Hmaidouch Naima Ouzeddoun loubna Benamar

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De Novo Glomerular Diseases after COVID-19 Vaccination: Consequence or Coincidence?

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Open Journal of Nephrology（肾脏病） 2024年第2期 233页

作者： Qods Yacoubi Salima Serroukh loubna Benamar Naima Ouzeddoun Tarik Bouattar

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Cerebral Glioblastoma in Renal Transplant Recipient: A Case Report

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Open Journal of Nephrology（肾脏病） 2024年第1期 10页

作者： Imane Saidi Meryem Benbella loubna Benamar Naima Ouzeddoun Tarik Bouattar

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Sliding mode approach applied to sensorless direct torque control of cage asynchronous motor via multi-level inverter

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Protection and Control of Modern Power Systems 2020年第1期5卷 166-175页

作者： Soukaina El Daoudi loubna Lazrak Mustapha Ait Lafkih Laboratory of Automatic Energy Conversion and MicroelectronicsFaculty of Sciences and TechnologySultan Moulay Slimane UniversityBeni MellalMorocco

To improve the robustness and performance of the dynamic response of a cage asynchronous motor,a direct torque control(DTC)based on sliding mode control(SMC)is adopted to replace traditional proportional-integral(PI)and hysteresis *** combination of the proposed strategy with sinusoidal pulse width modulation(SPWM)applied to a three-level neutral point clamped(NPC)inverter brings many advantages such as a reduction in harmonics,and precise and rapid tracking of the *** are performed for a three-level inverter with SM-DTC,a two-level inverter with SM-DTC and the three-level inverter with *** results show that the SM-DTC method achieves better performance in terms of reference tracking,while adoption of the threelevel inverter topology can effectively reduce the *** the SM-DTC to the three-level inverter presents the best solution for achieving efficient and robust *** addition,the use of a sliding mode speed estimator eliminates the mechanical sensor and this increases the reliability of the system.

关键词： Asynchronous cage motor Direct torque control Sinusoidal pulse width modulation Sliding mode control Speed estimator Three-level inverter

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Autosomal Dominant Polycystic Kidney Disease: Epidemiological, Clinical Aspects and Predictive Factors of Poor Renal Prognosis (About 300 Cases)

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Open Journal of Nephrology（肾脏病） 2024年第2期 275页

作者： Rihab Dkhissi Nada El Kadiri Tarik Bouattar loubna Benamar Naima Ouzeddoun

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