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Scorpion envenomation study in Behbahan County,Southwest Iran

Journal of Coastal Life Medicine 2014年第5期 416-420页

作者： Hamid Kassiri Ali Kassiri Mona Sharififard Samaneh Shojaee Masoud lotfi elnaz Kasiri School of Health Ahvaz Jundishapur University of Medical SciencesAhvazIran School of Medicine Ahvaz Jundishapur University of Medical SciencesAhvazIran Mazandaran University of Medical Sciences SariIran

Objective:To study the incidence and epidemiology of scorpion sting cases that were referred to the health services centers of Behbahan County,Khuzistan Province,southwestern Iran,during the two yeare(2007-2008).Methods:In this descriptive retrospective research,the data has come from files of scorpion-stung patients referring to the health services centers of Behbahan during study period.A special scorpion sting sheet was prepared and completed for every case of scorpion *** of 3441 case sheets received during this period was carried *** frequencies of medical and entomo-epidemiologic parameters were turned to the percentage ***:A total of 3441 cases of scorpion stings were reported during the two-year period from 2007 to *** average incidence of scorpion stings was 8.8‰in the two *** frequency of cases was higher during August,September,June and July that 2056 cases of scorpion stings were *** stings were occurred during *** 51.3%of the cases were *** cases had received *** of scorpion sting cases(56.5%)lived in the rural *** most common sting site was the *** 74.4%have received the antivenin 0-6 h after the *** early injection of the antivenin is very *** most of the cases of scorpion stings(59%)were occurred by yellow ***:Surveillance for cases of scorpion stings must begin at all regions of Behbahan *** of cases of scorpion stings is conducted according to a protocol set by the Ministry of Health,Treatment and Medical *** protocol included directions for lines of treatment and the dose of antivenin *** all cases are referred to hospital for further observation and management.

关键词： epidemiology Scorpion sting Incidence rate Iran

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伊朗亚兹德小儿斜视的流行与手术结果的调查研究(英文)

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国际眼科杂志 2013年第8期13卷 1521-1524页

作者： Besharati Mohammad Reza Manaviat Masoud Reza Kyian Mojgan lotfi Mohammad Hassan 沙希德Sadoughi医科大学老年眼科研究中心伊朗亚兹德沙希德Sadoughi医科大学普通内科老年眼科研究中心伊朗亚兹德沙希德Sadoughi医科大学保健学院流行病及统计学系伊朗亚兹德

目的: 对伊朗亚兹德不同类型斜视的发病率及术后效果的调查。方法: 在此描述性研究中,对年龄低于 16 岁患斜视人群的医疗记录进行回顾性分析。收集术后效果及并发症的问卷数据,对其进行统计学分析。卡方检验用于定性分析,曼-惠特尼 U... 详细信息

目的: 对伊朗亚兹德不同类型斜视的发病率及术后效果的调查。方法: 在此描述性研究中,对年龄低于 16 岁患斜视人群的医疗记录进行回顾性分析。收集术后效果及并发症的问卷数据,对其进行统计学分析。卡方检验用于定性分析,曼-惠特尼 U 检验用于定量分析。结果: 11a 间有 685 例儿童性斜视确诊。斜视类型如下:307 例 ( 44. 8% ) 外斜视,294 例 ( 42. 9% ) 内斜视,84 例( 12. 2%) 水平斜视合并垂直斜视。术后 280 例( 73. 9%)调整到正常水平( 水平偏差范围< 8Δ) 。结论: 研究中最常见的类型为外斜视。术后效果与已发表文献具有可比性。但仍需较长时间随访以评估手术效果。

关键词：小儿斜视外斜视内斜视斜视手术对准

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Prevalence and Correlates of Obesity and Overweight in Tunisian Bipolar I Patients

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Neuroscience & Medicine 2013年第3期4卷 181-187页

作者： Asma ezzaher Anwar Mechri Dhouha Haj Mouhamed Wahiba Douki lotfi Gaha Mohamed Fadhel Najjar Biochemistry and Toxicology Laboratory Monastir University Hospital Monastir Tunisia Research Laboratory “Vulnerability to Psychotic Disorders LR 05 eS 10” Department of Psychiatry Monastir University Hospital Monastir Tunisia.

Objective: We aim to determine the prevalence of obesity and overweight in bipolar I patients, and to examine their associations with the demographic, clinical and therapeutic characteristics of this population. Patients and Methods: Our study included 120 bipolar I patients (79 men and 41 women, mean age = 39.5 ± 11.9 years). Weight and height were evaluated by body mass index (BMI). Obesity was defined when BMI ≥ 30 kg/m2 and overweight when BMI ≥ 25 kg/m2. Results: The prevalence of obesity and overweight was respectively 32.5% and 30.8%. Obesity was significantly more frequent in women than men. The illness duration was significantly longer in obese patients than in those with normal weight. Moreover, the family history of medical disorders and concomitant medical disorders was significantly more frequent in obese patients than in those with normal weight. However, any significant association between therapeutic characteristics and obesity or overweight was found. Conclusions: Obesity and overweight were frequent in bipolar I patients. Obesity was significantly frequent in women and significantly associated with illness duration, medical disorders, and concomitant medical disorders. These results emphasized the need for specific treatment strategies and programs for weight control for these patients.

关键词： Bipolar I Disorder Obesity Overweight

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Serologic survey of cytomegalovirus and rubella virus in Tabriz,Iran

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Journal of Coastal Life Medicine 2015年第12期 971-974页

作者： Samad Farhadi Farnaz Faraji elnaz Babaei Hamid Reza lotfi Nader Hajizadeh Hakimeh Rasoolian Department of Central Laboratory Tabriz University of Medical SciencesTabrizIran Department of Laboratory Tabriz Children HospitalTabrizIran Young Researchers and elite Club Ilkhchi BranchIslamic Azad UniversityIlkhchiIran Department of Biology Ahar branchIslamic Azad UniversityAharIran

Objective:To determine the prevalence of rubella and cytomegalovirus(CMV)among women in Tabriz City,Iran in ***:This study was carried out in numerous laboratories in city of *** 2013,26618 women aged 18-35 years were enrolled in this *** samples were analyzed with chemiluminescence apparatus and SPSS software was used to conduct the statistical ***:A total of 26618 individuals were examined(10598 cases for anti-CMV and 16020 cases for anti-rubella).About 98.9%and 1.1%samples were reported positive and negative for CMV immunoglobulin G(IgG),*** positivity for anti-CMV immunoglobulin M(IgM)antibody was found in 0.75%samples,while 99.25%were negative for the anti-CMV IgM ***-IgG against rubella seropositivity was found in 95.8%and rubella IgM seropositivity in 0.93%.Anti-IgG against rubella seronegativity was found in 4.2%and rubella IgM seronegativity in 99.07%.Conclusions:According to the results,primary and secondary infections are usually symptomless or inconspicuous,but they can cause serious fetal *** antenatal care should therefore include serological testing to check the immune status of the woman and to diagnose any fresh virus infections that may arise.

关键词： Rubella Cytomegalovirus Tabriz Chemiluminescence Seroprevalence

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肯特州立大学eSL教学中心阅读教材真实性研究

外语教育与应用

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外语教育与应用 2022年第1期8卷 39-45页

作者：卢璐 Amal lotfi Laba 四川外国语大学成都学院翻译学院

本研究考察肯特州立大学eSL教学中心阅读课程中真实材料的使用情况,并探讨师生对阅读课上使用真实材料的见解。基于文本分析、小组访谈和问卷调查,研究发现eSL教学中心的阅读教材普遍采用不同类型的真实材料,并且教师和学生都认为真实... 详细信息

本研究考察肯特州立大学eSL教学中心阅读课程中真实材料的使用情况,并探讨师生对阅读课上使用真实材料的见解。基于文本分析、小组访谈和问卷调查,研究发现eSL教学中心的阅读教材普遍采用不同类型的真实材料,并且教师和学生都认为真实材料对阅读技能、词汇学习和批判性思维能力等都有帮助。研究结果将为eSL/eFL阅读教材编写和教师使用真实材料提供一定参考。

关键词：阅读教材真实材料肯特州立大学

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Tuberculous Meningitis and COVID-19 Co-Infection: About a Case

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Open Journal of Clinical Diagnostics 2021年第2期11卷 52-58页

作者： Ayoub Maaroufi Abdellatif Diai Nouredine Jebbar lotfi Bibiche Kaissi Jaber Nabil Jbili Hicham Kechna Jaouad Laoutid CHU Hassan II Fes Morocco

We report the case of an adult patient diagnosed with acute SARS-CoV-2-associated meningoencephalitis based on the detection of its RNA on a nasopharyngeal swab, cerebrospinal fluid analysis. The most destructive type of extrapulmonary tuberculosis is tuberculous meningitis, in which the consequences are severe, resulting in death or disability in almost half of all sufferers despite anti-tuberculosis chemotherapy. The aim of this study was to assess the clinical and paraclinical features and laboratory findings and outcome of a patient with tuberculous meningitis and COVID-19 coinfection. Infection of COVID-19 and lymphopenia promotes the development of the severe form of tuberculosis. On the other hand, TBM increased the risk of infection with coronavirus due to the weakened immune system in addition to other immunosuppressive factors (older age and comorbidities such as low socioeconomic status and malnutrition). The patient had a good recovery even if he required intensive neurorehabilitation for a month due to poor feeding and weakness. Treatment, both anti-mycobacterial and anti-inflammatory, early started, guaranteed good recovery.

关键词： Tuberculous Meningitis Meningoencephalitis COVID-19 Critical Care

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Investigation of Affecting Factors on Persistence in the Treatment of Patients under Methadone Maintenance Therapy in Addiction Therapy Centers, Yazd-Iran

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Health 2015年第5期7卷 606-616页

作者： Mohammad Reza Vafaeinasab Mohammad Hadi Farahzadi Omran Mohammad Razaghi Reza Ali Fallahzadeh Mohammad Hasan lotfi Shahin Akhondzadeh Faculty of Medicine Shahid Sadoughi University of Medical Sciences Yazd Iran Department of Neuroscience Faculty of Advanced Technologies in Medicine Tehran University of Medical Sciences Tehran Iran Faculty of Medicine Tehran University of Medical Sciences and Health Services Tehran Iran Department of environmental Health Faculty of Public Health Shahid Sadoughi University of Medical Sciences Yazd Iran Faculty of Public Health Shahid Sadoughi University of Medical Sciences Yazd Iran Psychiatric Research Center Roozbeh Hospital Tehran University of Medical Sciences Tehran Iran

Drug addiction is one of the current world’s hygienic, mental and social problems. There are different treatments for this illness. MMT (Methadone Maintenance Therapy) is considered as a standard and acceptable therapy for addiction;and there are many affecting factors regarding gaining success in this type of treatment. In this study, we investigated some of these factors. One of the most important issues in MMT is to keep up patient on his/her treatment till complete abstinence;therefore, it is recommended that the patient does not leave his/her therapy without discretion of the therapist. In this study, 230 patients, who began MMT, and admitted to addiction treatment centers of Yazd province were included. In this study, the survival rate in the first, third, and sixth months were evaluated as 93.9%, 63.48%, and 28.36%, respectively. It was found that following parameters are important in rate of survival during treatment: family support, gender, dose of methadone and concomitant use of morphine during treatment. Moreover, factors like level of education, marital status, age and concomitant use of methamphetamine during treatment can be effective in this regard.

关键词： MMT Addiction Persistence in the Treatment Yazd

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角膜胶原蛋白交联疗法对人工晶状体大泡性角膜病变的作用(英文)

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国际眼科杂志 2014年第5期14卷 785-789页

作者： Mohammad Mirzaei Nazli Taheri Mohammad Bagher Rahbani Nobar Afshin lotfi Sedigh Amin Najafi Samira Mirzaei 大不里士医科大学 Nikookari眼科医院眼科伊朗东阿塞拜疆*** 大不里士医科大学 Alavi眼科医院眼科伊朗东阿塞拜疆*** 大不里士医科大学医学院伊朗东阿塞拜疆***

目的:研究核黄素和紫外线(UVA)交联疗法对晚期大泡性角膜病的疗效。方法:15例人工晶状体大泡性角膜病变(PBK)患者参与研究。分别于角膜交联前和干预后1,6mo,对患者行裂隙灯检查、视敏度、异物调查表、角膜透明度分级、眼部疼痛度范围、... 详细信息

目的:研究核黄素和紫外线(UVA)交联疗法对晚期大泡性角膜病的疗效。方法:15例人工晶状体大泡性角膜病变(PBK)患者参与研究。分别于角膜交联前和干预后1,6mo,对患者行裂隙灯检查、视敏度、异物调查表、角膜透明度分级、眼部疼痛度范围、分析仪角膜厚度分析及超声波角膜厚度测量。氯化钠溶液处理1wk后,去除8mm直径范围的中央角膜上皮,在角膜上频繁点滴核黄素30min,后行3min紫外线(UVA)照射交联疗法。结果:15例患者(5男,10女),平均年龄为66±13岁。平均随访时间6.2mo。治疗后1mo全眼角膜透明度统计结果明显优于术前(PeK)过程的可视化。

关键词：大泡性角膜病变角膜胶原交联角膜水肿测厚仪

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Association between Liver enzymes and Dyslipidemia in Yemeni Patients with Type Two Diabetes Mellitus

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Journal of Diabetes Mellitus 2021年第2期11卷 41-51页

作者： lotfi S. Bin Dahman Mariam A. Humam Omer H. Barahim Omer M. Barahman Mohamed A. Balfas Medical Laboratory Sciences Department College of Medicine and Health Sciences Hadhramout University Mukalla Yemen Medicine Department College of Medicine and Health Sciences Hadhramout University Mukalla Yemen Basic Medical Sciences College of Medicine and Health Sciences Hadhramout University Mukalla Yemen

The correlation between liver enzymes and lipid profile in T2D patients in the Yemeni population has been evaluated. This is a case-control study comprising 142 T2D patients and 142 healthy control subjects were carried out at the outpatient clinics of Ibn-Sina hospital, Mukalla, during the period from January to May 2020. Serum fasting blood glucose (FBG), total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) were analyzed using the Cobas Integra Plus 400 autoanalyzer. Also, anthropometric and blood pressure measurements were taken from each participant. Independent sample T-test and Pearson correlation coefficient were used. T2D patients had significantly higher FBG (P ≤ 0.0001), total cholesterol (P ≤ 0.0001), LDL-C (P ≤ 0.0001), and GGT (P ≤ 0.0001) while HDL-C was significantly lower in T2D patients (P = 0.021). In correlation analysis, serum GGT was positively associated with FBG (r = 0.216;P ≤ 0.0001), total cholesterol (r = 0.196;P = 0.0001), triglyceride (r = 0.123;P = 0.038), and LDL-C (r = 0.209;P ≤ 0.0001). Also, serum ALT was positively associated with FBG (r = 0.145, P = 0.014) and triglyceride (r = 0.172, P = 0.004). In conclusion, higher levels of ALT and GGT are used as the predictive biomarkers for NAFLD in T2D patients with hyperlipidemia. Thus, routine screening of liver enzymes and lipid profile in T2D patients is recommended for the early detection of liver abnormalities and diminish diabetes complications.

关键词： Liver enzymes Dyslipidemia Type 2 Diabetes Mellitus Yemeni Patients

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Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr-Cas9

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Animal Models and experimental Medicine 2019年第4期2卷 297-311页

作者： elise Dreano Marc Bacchetta Juliette Simonin Louise Galmiche Claire Usal lotfi Slimani Jérémy Sadoine Laurent Tesson Ignacio Anegon Jean-Paul Concordet Aurélie Hatton Lucile Vignaud Danielle Tondelier Isabelle Sermet-Gaudelus Marc Chanson Charles-Henry Cottart INSeRM 1151 INEMUniversitéde ParisParisFrance Département de Pédiatrie Gynécologie&Obstétrique et Département de Physiologie Cellulaire&MétabolismeUniversitéde GenèveGenèveSwitzerland Département de Pathologie APHPCHU Necker-Enfants MaladesParisFrance Centre de Recherche en Transplantation&Immunologie UMR 1064INSERMUniversitéde NantesNantesFrance Plateforme Trangénèse Rat&ImmunoPhénomique INSERM 1064&SFR François BonamyCNRS UMS3556NantesFrance Pathologie Imagerie&Biothérapies OrofacialesMontrougeFrance Plateforme Imageries du vivant Facultéde chirurgie dentaireUniversitéde ParisParisFrance INSeRM U1154 CNRS UMR7196MNHNTACGENEParisFrance AP-HP Centre Maladie Rare Mucoviscidose et Maladies du CFTRAssistance Publique Hôpitaux de ParisHôpital Necker-Enfants MaladesParisFrance Facultéde Médecine de Paris Universitéde ParisParisFrance Facultéde Pharmacie de Paris Universitéde ParisParisFrance

Background: Genetically engineered animals are essential for gaining a proper understanding of the disease mechanisms of cystic fibrosis(CF). The rat is a relevant laboratory model for CF because of its zootechnical capacity, size, and airway characteristics, including the presence of submucosal ***: We describe the generation of a CF rat model(F508 del) homozygous for the ***508 del mutation in the transmembrane conductance regulator(Cftr) gene. This model was compared to new Cftr-/-rats(CFTR KO). Target organs in CF were examined by histological staining of tissue sections and tooth enamel was quantified by micro-computed tomography. The activity of CFTR was evaluated by nasal potential difference(NPD) and short-circuit current measurements. The effect of VX-809 and VX-770 was analyzed on nasal epithelial primary cell cultures from F508 del ***: Both newborn F508 del and Knock out(KO) animals developed intestinal obstruction that could be partly compensated by special diet combined with an osmotic laxative. The two rat models exhibited CF phenotypic anomalies such as vas deferens agenesis and tooth enamel defects. Histology of the intestine, pancreas, liver, and lungs was normal. Absence of CFTR function in KO rats was confirmed ex vivo by short-circuit current measurements on colon mucosae and in vivo by NPD, whereas residual CFTR activity was observed in F508 del rats. exposure of F508 del CFTR nasal primary cultures to a combination of VX-809 and VX-770 improved CFTR-mediated ***: The F508 del rats reproduce the phenotypes observed in CFTR KO animals and represent a novel resource to advance the development of CF therapeutics.

关键词： animal models CFTR channel activity CFTR modulators cystic fibrosis primary cultures rat

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