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Journal of Chemistry and Chemical Engineering 2011年第1期5卷 73-81页

作者： Mohammed Mohsen Babatin lotfi Khezami Abdel-Rahman Barakat Ahmed EI-Gazzar Department of Mathematics and Chemistry Faculty of Science Al-lmam Muhammad bin Saud Islamic University Riyadh 11623Kingdom of Saudi Arabia

The practical synthesis of pseudonucleosides incorporating thiourea derivative by coupling of monosaccharides （D-glucose and D-galactose） per-O-acetylated glycosyl isothiocyanates and different heterocyclic hydrazide derivatives is reported. The method involves the preparation ofper-O-acetylated glycosyl isothiocyanates from per-O-acetylated sugars （two-step synthesis）, which couple with heterocyclic hydrazides from amines to give thiourea-linked pseudonucleosides. All newly synthesized pseudo-nucleosides were assayed against human lung cancer-cell lines （PG） and human liver cancer-cell lines （BEL-7402） in vitro. The 6,6-dimethyl-benzothiophen-3-carbo-hydrazide-4-one pseudonucleosides showed moderate inhibition against these two cancer-cell lines with ECs0 from 22.8 to 76.4 mM and from 54.9 to 82.4 mM, respectively. And the other compounds did not demonstrate any significant cytotoxicity even at concentrations up to 200 mM.

关键词： Glycosyl bromides glycosyl isothiocyanates heterocyclic hydrazides thiourea-linked pseudooucleosides cytotoxicity.

Epidemiological features,clinical manifestation and laboratory findings of patients with cutaneous leishmaniasis in Genaveh County,Bushehr Province,Southern Iran

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Journal of Coastal Life Medicine 2014年第12期 1002-1006页

作者： Hamid Kassiri Ali Kasiri Hossein Najafi Masoud lotfi Elnaz Kasiri School of Health Ahvaz Jundishapur University of Medical SciencesAhvazIran School of Medicine Ahvaz Jundishapur University of Medical SciencesAhvazIran Mazandaran University of Medical Sciences SariIran

Objective:To examine the epidemiological features of cutaneous leishmaniasis in Genaveh County,Southern ***:This descriptive study was conducted during 2004-2008.A questionnaire was completed for each case regarding age,gender,place of residence,the number and location of cutaneous leishmaniasis lesions *** active lesions were scraped with a sterile blade and the samples smeared onto glass slides,fixed with methanol,stained with Giemsa and examined under a light microscope for the presence of ***:Totally,135 cases of cutaneous leishmaniasis came to the health *** highest number of patients catching cutaneous leishmaniasis was found in 2006(n=54).Most cases(56.3%)occurred during *** most highly infected age group was 1 to 10 *** hands were the most affected parts of the *** 54%of the patients had one *** most cases(53.3%)occurred in rural ***:It is important for the health authorities to take powerful actions to control cutaneous ***,It is significant to prepare quick treatment of cases.

关键词： Cutaneous leishmaniasis Epidemiology Prevalence Iran

Epidemiological analysis of snakebite victims in southwestern Iran

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Journal of Acute Disease 2019年第6期8卷 260-264页

作者： Hamid Kassiri Iman Khodkar Shahnaz Kazemi Niusha Kasiri Masoud lotfi Department of Medical Entomology School of HealthAhvaz Jundishapur University of Medical SciencesAhvazIran Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Khorram-shahr County Health Center Abadan School of Medical SciencesAbadanIran Abdanan Health Center Ilam University of Medical SciencesIlamIran

Objective:To investigate the prevalence of snakebites and associated epidemiologic factors in Khorram-shahr County,Iran,between 2013 and ***:This was a cross-sectional descriptive-analytical *** was collected and recorded via *** data included gender,age,occurrence regions,bite site,time of being bitten,month and *** were analyzed by Chi-square and t-tests with SPSS version ***:A total of 102 cases of snakebites occurred in Khorram-shahr County of Khuzestan Province,southwestern *** were 75 men(73.5%)and 27 women(26.4%),without significant difference in *** highest frequency of snakebites was observed in the age group of 41-50 years with 28 cases(27.4%).In total,58 cases(56.9%)occurred in urban areas and 44 cases(43.1%)in rural *** statistically significant difference was observed between the age groups or residential *** occurred in May with 19 cases(18.6%),spring with 45(44.1%)and summer with 45(44.1%).The results showed significant difference among different seasons and months of the *** were in feet in 62 cases(60.8%)and hands in 36 cases(35.3%)which were bitten more than other organs,respectively,with significant difference among different bite sites in the *** highest and lowest frequencies of snakebites were observed between 18:00 and 24:00 with 43 cases(42.2%)and between 6:00 and 12:00 with 14 cases(13.7%),with a significant difference among different hours of the ***:Useful information about snakebites,venomous snakes,their hazards,prevention of bites and the importance of early hospital referral and treatment of victims should be provided to people using different educational tools.

关键词： Snakebite Epidemiology Prevalence Iran

A Novel Halotolerant Bacterium Isolated from El Golea Lake in Algeria and Antimicrobial Potential of this Strain

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Journal of Agricultural Science and Technology(A) 2013年第10期3卷 825-834页

作者： Nihel Klouche Khelil Nadia Aissaoui Fatima Nas Jean Luc Cayol lotfi Ghellai Laboratoire de Microbiologie Appliqude dt l 'Agro-Alimentaire au Biomedical et 3 1 'Environnement (LAMMABE) Ddpartement deBiologie Facult~ des Sciences de la Nature et de la Vie et des Sciences de la Terre et de l 'Univers Universite de Tlemcen 13000Algerie Faculte de Mddecine Universite de Tlemcen 13000 Algerie IRD UR 101 ExtrOmophiles IFR-BAIM Universit~ de Provence et de la Mediterranee'e ESIL 163 Avenue de Luminy F-13288Marseille cedex 09 France

A halotolerant, gram positive, motile and rod, was isolated from the E1 Gol6a lake of Ghardaia, Alegria and screened for its antimicrobial potential. The strain showed an inhibitory effect to gram positive and gram negative bacteria against Cladosporium spp. and a slight inhibitory effect against C. albicans using chloroform as the extraction solvent and the nutrient broth as production medium. 16S rRNA sequencing showed that the isolate named LMB3981 is a new taxon in the family of Bacillaceae （with 96% similarity）. The strain is close to Filobacillus milosensis and Bacillus haloalkaliphilum with 95% similarity. The phenotypic study showed differences between LMB3981 and two strains that are near and have confirmed the results of 16S rRNA sequencing by specific metabolic properties of the strain.

关键词： New taxa extremophile antimicrobial molecules halotolerant Bacillus genus El Golea Lake.

Multistage interband cascade photovoltaic devices with a bandgap of 0.23 eV operating above room temperature

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Chinese Science Bulletin 2014年第10期59卷 950-955页

作者： Hao Ye Hossein lotfi Lu Li Robert T.Hinkey Rui Q.Yang Lin Lei Joel C.Keay Matthew B.Johnson Tetsuya D.Mishima Michael B.Santos School of Electrical and Computer Engineering University of Oklahoma Norman OK USA Homer L. Dodge Department of Physics and Astronomy University of Oklahoma Norman OK USA

Interband cascade(IC)photovoltaic(PV)device structures,consisting of multiple discrete InAs/GaSb superlattice absorbers sandwiched between electron and hole barriers,were grown by molecular beam *** of the molecular beam epitaxy growth and material characterization of the structures are *** discrete absorber architecture enables certain advantages,such as high open-circuit voltage,high collection efficiency,high operating temperature,and smooth integration of cascade stages with different *** two-and three-stage ICPV devices presented in this article operate at room temperature with substantial open-circuit voltages at a cutoff wavelength of 5.3 lm(corresponding to a bandgap of 0.23 eV),the longest ever reported for room temperature PV *** device characteristics indicate a high level of current matching and demonstrate the advantages of the interband cascade approach in thermophotovoltaic cell design.

关键词： InAs GaSb superlattice Thermophotovoltaic Interband cascade devices

Antioxidant activity, volatile and nonvolatile composition of twoPhoenix dactylifera L. by-products

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Journal of Coastal Life Medicine 2017年第6期5卷 254-260页

作者： Amira Thouri Hassiba Chahdoura Amira El Arem Guido Flamini Aicha Jelled lotfi Achour Research Laboratory"Bioresources:Biology Integrative and Valorization" Higher Institute of Biotechnology of MonastirAvenue Tahar HaddedBP745000MonastirTunisia Dipartimento di Scienze Farmaceutiche Sede di Chimica Bioorganica e Biofarmaciavia Bonanno3356126PisaItaly Centro Interdipartimentale di Ricerca"Nutraceutica e Alimentazione per la Salute"Nutrafood University of PisaVia del Borghetto8056124PisaItaly Laboratory of Histology and Cytogenetic and Childhood Disease UR12ES10 Faculty of MedicineUniversity of Monastir5019MonastirTunisia

Objective:To examine the nonvolatile components of the date pulp and seeds of two minor Tunisian date palm cultivars Arechti and Korkobbi at besser stage and to investigate their antioxidant activity, their phytochemical compounds and their aromatic volatiles composition. Methods:The physico-chemical properties, the aroma composition, the mineral profile, the phytochemical content and thein vitro antioxidant activity of those two common date palm fruit varieties and those of their seeds were evaluated. All measurements were made at the besser stage, which showed the highest amount of secondary metabolites. Results:New volatiles compounds are detected in both flesh and seeds and the results revealed that those by products are a suitable source of mineral content and have a high potential of natural antioxidants and good antiradical capacities. Conclusions: Thanks to their characteristics, they could potentially be considered as a cheap resource for new functional food ingredient and novel pharmaceutical applications.

关键词： Date palm fruit Seeds Physicochemical composition Aroma composition Total phenolic content In vitro antioxidant activity

Urodynamic Findings in Young Women of Less Than Forty Years Old with Lower Urinary Tract Symptoms

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Open Journal of Urology 2012年第1期2卷 11-15页

作者： Hosein Karami Alireza Bagher Tabrizi Babak Javanmard Hooman Mokhtarpour Behzad lotfi Urology and Nephrology Research Center (UNRC) Shohada Medical Center Shahid Beheshti University Tehran Iran

Purpose: The aim of the study was to determine urodynamic findings in young women (<40 years old) with bothersome lower urinary tract symptoms. Materials and Methods: The records of 315 women were reviewed during 2002 to 2010. Those with neurological disease, history of urogenital malignancies, urethral stricture or trauma, acute UTI, unsterile urine analysis, congenital urological disease, pelvic organ prolapse, diabetes mellitus or a primary complaint of stress incontinence were excluded. All completed the American Urological Association Symptom Index (AUASI) and underwent urodynamic studies. Results: Bladder dysfunction was diagnosed in 78.4% of the patients with urge incontinence. Bladder and voiding phase dysfunction were found in 134 (42.5%) and 110 (34.9%) of patients, respectively. Occult neurological disease was later diagnosed in 10 women (3.17%) with urge incontinence and bladder dysfunction. Discussion: Urge incontinence and voiding symptoms are frequently associated with urodynamical abnormalities. Urge incontinence and bladder dysfunction may be a sign of occult neurological disease in this population. The presenting symptoms are useful in determining the advantage of urodynamic study in this population.

关键词： Urge Incontinence Women Urodynamics

The Effect of Pomegranate Paste on Neonatal Jaundice Incidence: A Clinical Trial in Women during Pregnancy

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International Journal of Clinical Medicine 2017年第3期8卷 144-151页

作者： Mohsen Manouchehrian Mehrdad Shakiba Mamak Shariat Mohammad Hassan lotfi Mohammad Kamalinejad Mohammad Babaeian Department of Traditional Medicine Shahid Sadoughi University of Medical Sciences Ardakan Iran Department of Pediatrics Shahid Sadoughi University of Medical Sciences Ardakan Iran Fetal & Neonatal Research Center Tehran University of Medical Sciences Tehran Iran Department of Biostatistics & Epidemiology Health Faculty Shahid Sadoughi University of Medical Sciences Ardakan Iran School of Pharmacy Shahid Beheshti University of Medical Sciences Tehran Iran

Purpose: Some topics such as women’s life style and nutrition and using some special medicines during pregnancy have been discussed and demonstrated as effective factors on infant’ health. Based on recommendations in Iranian traditional medicine, we aimed to evaluate the efficacy of pomegranate paste consumed by women during their pregnancy on the neonatal jaundice incidence. Methods: In this single-blinded controlled clinical trial, 80 healthy pregnant women were randomly divided into 2 groups, as treatment and control. The treatment group members added pomegranate paste to their daily diet from the 34th week of the pregnancy to birth, as administered. The levels of neonates’ bilirubin were checked in the 5th day of the delivery. Results: Both the need of phototherapy and the mean level of neonates’ bilirubin in the group fed with pomegranate paste were significantly lesser compared to control group. The number of neonates who were undergone phototherapy in the pomegranate paste receiving group was significantly lesser than that in the control group (P value = 0.029). By measuring the total bilirubin, statically significant difference between the treatment group and the control group was seen (P value = 0.021). Conclusion: The results of this study suggest the possible effect of adding pomegranate paste to pregnant women’s diet on the incidence of neonatal jaundice.

关键词： Pomegranate Hyperbilirubinemia Neonatal Jaundice Pregnancy Iranian Traditional Medicine

Long COVID in children and adolescents

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World Journal of Pediatrics 2021年第5期17卷 495-499页

作者： Ali A.Asadi-Pooya Hamid Nemati Mina Shahisavandi Ali Akbari Amir Emami Mehrzad lotfi Mahtab Rostamihosseinkhani Zohreh Barzegar Maryam Kabiri Zahra Zeraatpisheh Mohsen Farjoud-Kouhanjani Anahita Jafari Fateme Sasannia Shayan Ashrafi Masoume Nazeri Sara Nasiri Epilepsy Research Center Shiraz University of Medical SciencesShirazIran Department of Ncurology Jefferson Comprehensive Epilepsy CenterThomas Jefferson UniversityPhiladelphiaPAUSA Department of Anesthesiology School of Medicine.Shiraz University of Medical SciencesShirazIran Burn&Wound Healing Research Center Shiraz University of Medical SciencesShirazIran Medical Imaging Research Center Shiraz University of Medical SciencesShirazIran

Background To identify the prevalence and also the full spectrum of symptoms/complaints of children and adolescents who are suffering from long ***,we investigated the risk factors of long COVID in children and *** All consecutive children and adolescents who were referred to the hospitals anywhere in Fars province,Iran,from 19 February 2020 until 20 November 2020 were *** patients had a confirmed diagnosis of *** *** call to patients/parents,at least 3 months after their discharge from the hospital,we obtained their current status and information if their parents agreed to *** In total,58 children and adolescents fulillel the inclusion ***-six(448%)children/adolescents reported symptoms/complaints of long *** symptoms included fatigue in 12(21%),shortness of breath in 7(12%),exer-cise intolerance in 7(12%),weakness in 6(10%),and walking intolerance in 5(9%)*** age,muscle pain on admission,and intensive care unit admission were significantly associated with long *** Long COVID is a frequent condition in children and *** scientific community should inves-tigate and explore the pathophysiology of long COVID to ensure that these patients receive appropriate treatments for their condition.

关键词： Adolescents Children COVID-19 Coronavirus Chronic Pediatrics

Assessment of Effects of Stress among Healthcare Providers at the Tabarka and Jendouba General Hospital’s Emergency Service Units in Northern Tunisia

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Health 2015年第8期7卷 910-914页

作者： Neila Maaroufi Jalel Rzeigui lotfi Ayari Zeineb Abid Mahassen Dhaouadi Hadda Saidi Emergency Service General Hospital of Jendouba Jendouba Tunisia Emergency Service General Hospital of Tabarka Tabarka Tunisia

The study assessed the relationship between exposure to stress and posttraumatic symptoms among nurses and physicians in a Jendouba general hospital. Hospital staff who were exposed to stress were assessed for posttraumatic stress disorder. High levels of stress symptoms were found in physicians and nurses. Logistic regression analysis showed that nurses had an increased risk for posttraumatic stress disorder factors characterized by negative behavior to patient, increased workload excessive ambiguity and role conflict and the lack of free. These findings showed that nurses suffered from more severe posttraumatic symptoms compared to physicians after exposure to prolonged stress. The gap between physicians and nurses warrants further study.

关键词： Stress Hospital Personnel Nursing Depressive Symptoms Workload