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International Journal of Innovation Studies 2017年第2期1卷 107-133页

作者： Gianluca Vagnani loredana volpe Department of Management of Sapienza University of RomeCastro Laurenziano 9Roma 00191Italy

The adoption of innovations has emerged as one of the dominant research topic in the management of innovations in organizations,though investigations often yield mixed *** help managers and researchers improve the effectiveness of their efforts,the authors employed meta-analysis integrated by structural equation modeling to analyze the associations between the attributes of innovations,behavioral preferences of managers and organizations'innovation adoption decisions in a mediated-moderated *** findings offer evidences that attributes of innovations influence behavioral preferences of managers and,in turn,adoption decisions in *** also observe that the context in which the adoption decision takes place and the research settings employed by scholars ***,the theoretical contribution and practical implications of our meta-analytical results are discussed.

关键词： Attributes of innovations Managers'behavioral preferences Organizations'innovation adoption decisions Meta-analysis Mediation-moderation

A Constructive Method for Computing Generalized Manley-Rowe Constants of Motion

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Communications in Computational Physics 2013年第9期14卷 1094-1102页

作者： Elena Kartashova loredana Tec IFA J.Kepler UniversityLinz 4040Austria RISC J.Kepler UniversityLinz 4040Austria

The Manley-Rowe constants of motion(MRC)are conservation laws written out for a dynamical systemdescribing the time evolution of the amplitudes in resonant *** this paper we extend the concept of MRC to resonance clusters of any form yielding generalized Manley-Rowe constants(gMRC)and give a constructive method how to compute *** also give details of a Mathematica implementation of this *** provide integrability of the underlying dynamical system,gMRC generally do not but may be used for qualitative and numerical study of dynamical systems describing generic resonance clusters.

关键词： Resonance clusters Hamiltonian formulation discretewave turbulence NR-diagram invariants of motion

The role of an integration identity in the analysis of the Cauchy-Leray transform

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Science China Mathematics 2017年第11期60卷 1923-1936页

作者： LANZANI loredana STEIN Elias M. Department of Mathematics Syracuse University Department of Mathematics Princeton University

The purpose of this paper is to complement the results by Lanzani and Stein(2017) by showing the dense definability of the Cauchy-Leray transform for the domains that give the counter-examples of Lanzani and Stein(2017), where L^p-boundedness is shown to fail when either the "near" C^2 boundary regularity, or the strong C-linear convexity assumption is dropped.

关键词： Hardy space Cauchy integral Cauchy-Szego projection Lebesgue space pseudoconvex domain minimal smoothness Leray-Levi measure

Solvability of the Dirichlet Problem in W^(2,p )for a Class of Elliptic Equations with Singular Data

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Acta Mathematica Sinica,English Series 2014年第5期30卷 737-746页

作者： loredana CASO Roberta D'AMBROSIO Maria TRANSIRICO Dipartimento di Matematica Universit`a di SalernoVia Giovanni Paolo II 132I - 84084 Fisciano (SA) Italy

We prove an existence and uniqueness result for the Dirichlet problem for a class of elliptic equations with singular data in weighted Sobolev spaces.

关键词： Elliptic equations a priori estimates uniqueness and existence results weighted spaces

Role of new endoscopic techniques in inflammatory bowel disease management: Has the change come?

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World Journal of Gastroenterology 2017年第24期23卷 4324-4329页

作者： loredana goran lucian negreanu ana maria negreanu Internal Medicine Ⅱ Gastroenterology department University Hospital Carol Davila University of Medicine

Despite significant therapeutic progress in recent years,inflammatory bowel disease(IBD),which includes Crohn’s disease and ulcerative colitis,remains a challenge regarding its pathogenesis and long-term *** concepts have emerged in the management of this disease,such as the"treat-totarget"concept,in which mucosal healing plays a key role in the evolution of IBD,the risk of recurrence and the need for *** is essential for the assessment of mucosal inflammation and plays a pivotal role in the analysis of mucosal healing in patients with *** is also essential in the detection of dysplasia and in the identification of the risk of colon *** current surveillance strategy for dysplasia in IBD patients indicates white-light endoscopy with non-targeted *** new chromoendoscopy techniques provide substantial benefits for both clinicians and ***-band imaging(NBI)has similar rates of dysplastic lesion detection as whitelight endoscopy,and it seems that NBI identifies more adenoma-like *** it is used instinctively by many endoscopists,the combination of these two techniques might improve the rate of dysplasia *** spectral imaging color enhancement can help differentiate dysplastic and non-dysplastic lesions and can also predict the risk of recurrence,which allows us to modulate the treatment to gain better control of the *** combination of noninvasive serum and stool biomarkers with endoscopy will improve the monitoring and limit the evolution of IBD because it enables the use of a personalized approach to each patient based on that patient’s history and risk factors.

关键词： Chromoendoscopy Flexible spectral imaging color enhancement Inflammatory bowel disease Dysplasia Mucosal healing Narrow band imaging

Shape memory composite structures for self-deployable solar sails

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Astrodynamics 2019年第3期3卷 247-255页

作者： loredana Santo Denise Bellisario Leamdro Iorio Fabrizio Quadrini Department of Industrial Engineering University of Rome Tor VergataRome00133Italy

Shape memory composites(SMCs)combine mechanical performances of composite materials with functional behavior of shape memory *** can be used to produce the external frame of self-deployable solar sails with very low weight in comparison with traditional composite ***,heat activation is necessary for deploying instead of complex mechanical *** this study,the mechanical behavior of a solar sail with SMC frame is simulated by means of finite element *** considerations are made on sail deployment configuration,size/weight ratio of solar sails,and SMC *** experimental activity has been also performed to provide suitable candidates for the composite laminates of the SMC *** and instrumented recovery tests have been carried out on 2-plies carbon-fiber laminates with a shape memory interlayer.

关键词： solar sail shape memory composite finite element modeling carbon-fiber composite self-deployable structure

The role of an integration identity in the analysis of the Cauchy-Leraytransform

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中国科学：数学 2017年第11期47卷 J0001-J0006页

作者： LANZANI loredana STEIN Elias M. Department of Mathematics Syracuse University Department of Mathematics Princeton University

The purpose of this paper is to complement the results by Lanzani and Stein （2017） by showing thedense definability of the Cauchy-Leray transform for the domains that give the counter-examples of Lanzani andStein （2017）, where LP-boundedness is shown to fail when either the ＂near＂ C2 boundary regularity, or the strongC-linear convexity assumption is dropped.

关键词： Hardy space Cauchy integral Cauchy-Szego projection Lebesgue space pseudoconvex do-main minimal smoothness Leray-Levi measure

The role of antioxidant therapy in the treatment of male infertility： an overview

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Asian Journal of Andrology 2011年第5期13卷 690-697页

作者： Francesco Lombardo Andrea Sansone Francesco Romanelli DonateUa Paoli loredana Gandiniand Andrea Lenzi Department of Experimental Medicine Policlinico ＇Umberto I＇ University of Rome ＇La Sapienza＇ Rome 00161 Italy

In recent years, many studies have focused on the effect of oxidative stress, reactive oxygen species （ROS） and antioxidants on the male eproductive system. Under physiological conditions, sperm produces small amounts of ROS, which are needed for fertilisation, acrosome reaction and capacitation. However, if an increased production of ROS is not associated with a similar increase in scavenging systems, peroxidative damage of the sperm plasma membrane and loss of DNA integrity typically occur, which leads to cell death and reduced fertility. Furthermore, since there is no linear correlation between sperm quality and pregnancy rates, an improvement in semen parameters should not be the sole outcome considered in studies of antioxidant therapies. A definitive conclusion regarding the benefit of these therapies is difficult to obtain, as most of the previous studies lacked control groups, considered different antioxidants in different combinations and doses, or did not evaluate pregnancy rates in previously infertile couples. Even if beneficial effects were reported in a few cases of male infertility, more multicentre, double-blind studies performed with the same criteria are necessarv for an increased understanding of the effects of various antioxidants on fertility,

关键词： antioxidants male infertility oxidative stress reactive oxygen species

Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa

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Asian Journal of Andrology 2017年第4期19卷 409-413页

作者： Donatella Paoli Marianna Pelloni Mariagrazia Gallo Giulia Coltrinari Francesco Lombardo Andrea Lenzi loredana Gandini Laboratory of Seminology - Sperm Bank Department of Experimental Medicine University of Rome 'La Sapienza' 00161 Rome Italy

It has been suggested that the energy required for sperm motility is produced by oxidative phosphorylation while glycolysis seems to be an important source for ATP transmission along the flagellum. Some studies have investigated the chemical and kinetic properties of the enzyme glyceraldehyde 3-phosphate dehydrogenase to identify any changes in the regulation of glycolysis and sperm motility. In contrast, there are few studies analyzing the genetic basis of hypokinesis. For this reason, we investigated the glyceraldehyde 3-phosphate dehydrogenase gene in human sperm to evaluate whether asthenozoospermia was correlated with any changes in its expression. Semen examination and glyceraldehyde 3-phosphate dehydrogenase gene expression studies were carried out on 116 semen samples divided into two groups - Group A consisted of 58 normokinetic samples and Group B of 58 hypokinetic samples. Total RNA was extracted from spermatozoa, and real-time PCR quantification of mRNA was carried out using specific primers and probes. The expression profiles for the Groups A and B were very similar. The mean delta Ct was as follows - Group A, 5.79 ＋ 1.04; Group B, 5.47 ＋ 1.27. Our study shows that in human sperm, there is no difference in glyceraldehyde 3-phosphate dehydrogenase gene expression between samples with impaired motility and samples with normal kinetics. We believe that this study could help in the understanding of the molecular mechanisms of sperm kinetics, suggesting that hypomotility may be due to a possible posttranscriptional impairment of the control mechanism, such as mRNA splicing, or to posttranslational changes.

关键词： adenosine-5'-triphosphate gene expression sperm glyceraldehyde 3-phosphate dehydrogenase sperm motility

Induction of oxidative stress in human aqueous and vitreous humors by Nd:YAG laser posterior capsulotomy

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International Journal of Ophthalmology(English edition) 2018年第7期11卷 1145-1151页

作者： loredana BergANDi Oleksii A Skorokhod Federica Franzone Rosalba La Grotta Evelin Schwarzer Raffaele Nuzzi Department of Oncology University of Torino Department of Molecular Biosciences the Wenner-Gren Institute Stockholm University Eye Clinic Section and Specialization School in Ophthalmology Department of Surgical Sciences University of Torino

AIM： To evaluate whether the Q-switched Nd：YAG laser treatment applied in routine capsulotomy elicits oxidative stress in aqueous and vitreous humors. METHODS： Thirty-six patients who had to undergo a 25 gauge pars plana vitrectomy due to vitreoretinal disorders were enrolled, 15 of them underwent a Q-switched Nd：YAG laser capsulotomy 7 d before vitrectomy due to posterior capsule opacification（PCO）（Nd：YAG laser group） while the remaining 21 patients were not laser treated before vitrectomy（no Nd：YAG laser group）. Samples of the aqueous and vitreous humors were collected during vitrectomy from all patients for the assessment of oxidative parameters which were compared between the Nd：YAG laser group and no Nd：YAG laser group. Thiobarbituric acid reactive substances（TBARS）, a product of membrane lipid peroxidation, nitrite levels, the antioxidative activities of SOD and catalase, the 4-HNE-protein conjugate formation, indicating structural modifications in proteins due to lipoperoxidation, were assessed in aqueous and vitreous samples. RESULTS： In the human vitreous humor TBARS levels are significantly higher in the Nd：YAG laser group compared to the no Nd：YAG laser group and importantly, there is a significant correlation between the TBARS levels and the total energy of Nd：YAG laser used during *** the anti-oxidative activities of SOD and catalase were significantly decreased by Nd：YAG laser treatment, both in aqueous and vitreous humors. In accordance with the TBARS data and anti-oxidative enzyme activities, significantly higher levels of proteins were conjugated with the lipoperoxidation product 4-HNE in the aqueous and vitreous humors in the Nd：YAG laser-treated group in comparison to no Nd：YAG laser group. CONCLUSION： These data, clearly suggest that any change that Q-switched Nd：YAG photo disruption may cause in the aqueous and vitreous compartments, resulting in a higher level of oxidative damage might be of considerable clinical significance

关键词： posterior capsule opacification Q-switched Nd:YAG laser oxidative stress vitrectomy