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A mathematical model to assess the impact of testing and isolation compliance on the transmission of COVID-19

Infectious Disease Modelling 2023年第2期8卷 427-444页

作者： Shasha Gao Pant Binod Chidozie Williams Chukwu Theophilus Kwofie Salman Safdar lora newman Seoyun Choe Bimal Kumar Datta Wisdom Kwame Attipoe Wenjing Zhang P.van den Driessche School of Mathematics and Statistics Jiangxi Normal UniversityNanchang330000JiangxiChina Department of Mathematics University of FloridaGainesville32611FLUSA Department of Mathematics University of MarylandCollege Park20742MDUSA Department of Mathematics Wake Forest UniversityWinston-Salem27109NCUSA School of Mathematical and Statistical Sciences Arizona State UniversityTempe85287AZUSA Department of Mathematical Sciences University of CincinnatiCincinnati45221OHUSA Department of Mathematics University of Central FloridaOrlando32816FLUSA Department of Mathematical Sciences Florida Atlantic UniversityBoca Raton33431FLUSA Department of Mathematics Clarkson UniversityPotsdam13699NYUSA Department of Mathematics and Statistics Texas Tech UniversityLubbock79409TXUSA Department of Mathematics and Statistics University of VictoriaVictoriaV8W 2Y2B.CCanada

The COVID-19 pandemic has ravaged global health and national economies *** and isolation are effective control strategies to mitigate the transmission of COVID-19,especially in the early stage of the disease *** this paper,we develop a deterministic model to investigate the impact of testing and compliance with isolation on the transmission of *** derive the control reproduction number R_(C),which gives the threshold for disease elimination or *** data from New York State in the early stage of the disease outbreak,we estimate R_(C)=7:*** elasticity and sensitivity analyses show that testing and compliance with isolation are significant in reducing R_(C) and disease *** reveals that only high testing volume combined with a large proportion of individuals complying with isolation have great impact on mitigating the *** testing starting date is also crucial:the earlier testing is implemented,the more impact it has on reducing the *** results obtained here would also be helpful in developing guidelines of early control strategies for pandemics similar to COVID-19.

关键词： COVID-19 Testing Compliance Isolation New York state

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