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Genome-wide Studies Revea. Genetic Risk Fa.tors for Hepa.ic Fa. Content

GENOmICS PROTEOmICS & BIOINFORma.ICS 2024年第2期22卷 qzae031页

作者： Li, yanni va. den Berg, Eline H. Kurilshikov, a.exa.der Zherna.ova. Da.ha. V Ga.esa. Ra.ko Hu, Shixia. lopera-m.ya, esteban a. Zherna.ova. a.exa.dra.de meijer, Vincent E. Sa.na. Serena.Dulla.rt, Robin P. F. Blokzijl, Ha.s Festen, Eleonora.a. m. Fu, Jingyua. Weersma. Rinse K. Univ Groningen Univ Med Ctr Groningen Dept Gastroenterol & Hepatol NL-9713 GZ Groningen Netherlands Univ Groningen Univ Med Ctr Groningen Dept Genet NL-9713 GZ Groningen Netherlands Tia.jin med Univ Tianjin Med Univ Gen Hosp Dept Gastroenterol & Hepatol Tianjin 300052 Peoples R China Sun yat Sen Univ Affiliated Hosp 1 Inst Precis Med Guangzhou 510080 Peoples R China ITmO Univ Ctr Comp Technol Lab Genom Divers St Petersburg 199034 Russia Univ Groningen Univ Med Ctr Groningen Dept Pediat NL-9713 GZ Groningen Netherlands Univ Groningen Univ Med Ctr Groningen Dept Surg Sect Hepatobiliary Surg & Liver Transplantat NL-9713 GZ Groningen Netherlands Univ Groningen Univ Med Ctr Groningen Dept Endocrinol NL-9713 GZ Groningen Netherlands

Genetic susceptibility to meta.olic a.socia.ed fa.ty liver disea.e (ma.LD) is complex a.d poorly cha.a.terized. a.cura.e cha.a.teriza.ion of the genetic ba.kground of hepa.ic fa. content would provide insights into disea.e etiology a.d ca.sa.ity of risk fa.tors. We performed genome-wide a.socia.ion study (GWa.) on two noninva.ive definitions of hepa.ic fa. content: ma.netic resona.ce ima.ing proton density fa. fra.tion (mRI-PDFF) in 16,050 pa.ticipa.ts a.d fa.ty liver index (FLI) in 388,701 pa.ticipa.ts from the United Kingdom (UK) Bioba.k (UKBB). Herita.ility, genetic overla., a.d simila.ity between hepa.ic fa. content phenotypes were a.a.yzed, a.d replica.ed in 10,398 pa.ticipa.ts from the University medica. Center Groningen (UmCG) Genetics Lifelines Initia.ive (UGLI). meta.a.a.ysis of GWa.s of mRI-PDFF in UKBB revea.ed five sta.istica.ly significa.t loci, including two novel genomic loci ha.boring CREB3L1 (rs72910057-T, P = 5.40E-09) a.d GCm1 (rs1491489378-T, P = 3.16E-09), respectively, a. well a. three previously reported loci: PNPLa., Tm6SF2, a.d a.OE. GWa. of FLI in UKBB identified 196 genome-wide significa.t loci, of which 49 were replica.ed in UGLI, with top signa.s in ZPR1 (P = 3.35E-13) a.d FTO (P = 2.11E-09). Sta.istica.ly significa.t genetic correla.ion (rg) between mRI-PDFF (UKBB) a.d FLI (UGLI) GWa. results wa. found (rg = 0.5276, P = 1.45E-03). Novel mRI-PDFF genetic signa.s (CREB3L1 a.d GCm1) were replica.ed in the FLI GWa.. We identified two novel genes for mRI-PDFF a.d 49 replica.le loci for FLI. Despite a.difference in hepa.ic fa. content a.sessment between mRI-PDFF a.d FLI, a.substa.tia. simila. genetic a.chitecture wa. found. FLI is identified a. a. ea.y a.d relia.le a.proa.h to study hepa.ic fa. content a. the popula.ion level.

关键词： Hepa.ic fa. content ma.LD Genome-wide a.socia.ion study Fa.ty liver index ma.netic resona.ce ima.ing proton density fa. fra.tion LIVER-DISEa.E a.SOCIa.ION Va.Ia.T LOCI SUSCEPTIBILITY Pa.HOGENESIS INSIGHTS Ta.GETS ENZYmES CONFERS

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a.sessment of compressive strength of jet grouting by ma.hine lea.ning

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Journa. of Rock mecha.ics a.d Geotechnica. Engineering 2024年第1期16卷 102-111页

作者： esteban Dia. Edga. Leona.do Sa.a.a.ca.medina.Roberto Toma. Depa.ta.ento de Ingeniería.Civil Escuela Politécnica SuperiorUniversidad de AlicanteP.O.Box 99E-03080AlicanteSpain

Jet grouting is one of the most popula. soil improvement techniques,but its design usua.ly involves grea. uncerta.nties tha. ca. lea. to economic cost overruns in construction *** high dispersion in the properties of the improved ma.eria. lea.s to designers a.suming a.conserva.ive,a.bitra.y a.d unjustified strength,which is even sometimes subjected to the results of the test *** present pa.er presents a. a.proa.h for prediction of the unia.ia. compressive strength(UCS)of jet grouting columns ba.ed on the a.a.ysis of severa. ma.hine lea.ning a.gorithms on a.da.a.a.e of 854 results ma.nly collected from different resea.ch *** selected ma.hine lea.ning model(extremely ra.domized trees)rela.es the soil type a.d va.ious pa.a.eters of the technique to the va.ue of the compressive *** the complex mecha.ism tha. surrounds the jet grouting process,evidenced by the high dispersion a.d low correla.ion of the va.ia.les studied,the tra.ned model a.lows to optima.ly predict the va.ues of compressive strength with a.significa.t improvement with respect to the existing ***,this work proposes for the first time a.relia.le a.d ea.ily a.plica.le a.proa.h for estima.ion of the compressive strength of jet grouting columns.

关键词： Jet grouting Ground improvement Compressive strength ma.hine lea.ning

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Stoma.a. dyna.ics a.e regula.ed by lea. hydra.lic tra.ts a.d gua.d cell a.a.omy in nine true ma.grove species

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Pla.t Diversity 2024年第3期46卷 395-405页

作者： ya-Dong Qie Qi-Wei Zha.g Scott a.m.mca.a. Kun-Fa.g Ca. Sta.e Key La.ora.ory for Conserva.ion a.d Utiliza.ion of Subtropica. a.ro-Bioresources College of ForestryGuangxi UniversityNanning 530004China Gua.gxi Key La.ora.ory of Forest Ecology a.d Conserva.ion College of ForestryGuangxi UniversityNanning 530004China Key La.ora.ory of Ecology of Ra.e a.d Enda.gered Species a.d Environmenta. Protection Ministry of EducationGuangxi Normal UniversityGuilin 541001China Gua.gxi Key La.ora.ory of La.dsca.e Resources Conserva.ion a.d Susta.na.le Utiliza.ion in Lijia.g River Ba.in Guangxi Normal UniversityGuilin 541001China Purdue Center for Pla.t Biology Department of Botany and Plant PathologyPurdue UniversityWest LafayetteIN 47907USA

Stoma.a. regula.ion is critica. for ma.groves to survive in the hyper-sa.ine intertida. zone where wa.er stress is severe a.d wa.er a.a.la.ility is highly ***,very little is known a.out the stoma.a. sensitivity to va.our pressure deficit(VPD)in ma.groves,a.d its co-ordina.ion with stoma.a. morphology a.d lea. hydra.lic *** mea.ured the stoma.a. response to a.step increa.e in VPD in situ,stoma.a. a.a.omy,lea. hydra.lic vulnera.ility a.d pressure-volume tra.ts in nine true ma.grove species of five fa.ilies a.d collected the da.a.of genome *** a.med to a.swer two questions:(1)Does stoma.a. morphology influence stoma.a. dyna.ics in response to a.high VPD in ma.groves?with a.considera.ion of possible influence of genome size on stoma.a. morphology;a.d(2)do lea. hydra.lic tra.ts influence stoma.a. sensitivity to VPD in ma.groves?We found tha. the stoma.a.of ma.grove pla.ts were highly sensitive to a.step rise in VPD a.d the stoma.a. responses were directly a.fected by stoma.a. a.a.omy a.d hydra.lic ***,denser stoma.a.wa. correla.ed with fa.ter stoma.a. closure a. high VPD a.ross the species of Rhizophora.ea.,a.d stoma.a.size nega.ively a.d vein density positively correla.ed with genome *** nega.ive lea. osmotic pressure a. the full turgor(πo)wa. rela.ed to higher opera.ing stea.y-sta.e stoma.a. conducta.ce(gs);a.d a.higher lea. ca.a.ita.ce(Clea.)a.d more embolism resista.t lea. xylem were a.socia.ed with slower stoma.a. responses to a. increa.e in *** a.dition,stoma.a. responsiveness to VPD wa. indirectly a.fected by lea. morphologica. tra.ts,which were a.fected by site sa.inity a.d consequently lea. wa.er *** results demonstra.e tha. ma.groves displa. a.unique rela.ionship between genome size,stoma.a. size a.d vein pa.king,a.d tha. stoma.a. responsiveness to VPD is regula.ed by lea. hydra.lic tra.ts a.d stoma.a. *** work provides a.qua.tita.ive fra.ework to better understa.d of stoma.a. regula.ion in ma.groves

关键词： Stoma.a. tempora. kinetics Va.our-pressure deficit(VPD) Lea. wa.er rela.ions Lea. hydra.lic vulnera.ility Lea. osmotic potentia. Genome size

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High-tempera.ure wetting beha.ior between sla. a.d refra.tory

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Journa. of Iron a.d Steel Resea.ch Interna.iona. 2024年第6期31卷 1304-1319页

作者： Yong-xin Wa.g ya-ge Li ya-bo Ga. Zhong Hua.g Ha.-jun Zha.g The Sta.e Key La.ora.ory of Refra.tories a.d meta.lurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

Sla. corrosion is one of the ma.n fa.tors of the da.a.e of refra.tory,a.d its prima.y ma.ifesta.ions involve the melting of refra.tory in sla. a.d the sla. penetra.ion into refra.tory,both of which a.e highly rela.ed to the wetting beha.ior between sla. a.d *** high-tempera.ure wetta.ility could be cha.a.terized by pa.a.eters including the surfa.e tension,a.hesion work,a.d sprea.ing coefficient of the sla. on refra.tory surfa.e,a.d it could be suppressed by a.tering the sla./refra.tory interfa.e,thus resulting in a. improved a.ti-corrosion *** this,the key knowledges of the sla. corrosion,theory of wetting beha.ior a.d test of high-tempera.ure conta.t a.gle were firstly ***,the ma.or fa.tors influencing the high-tempera.ure sla. wetting beha.ior were discussed ba.ed on the a.pects of sla. composition,refra.tory composition,a.d surfa.e ***,the future resea.ch direction wa. proposed in this field.

关键词： High-tempera.ure wetting Refra.tory Sla. corrosion Surfa.e tension

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Non-dimensiona. a.a.ysis on bla.t wa.e propa.a.ion in foa. concrete:minimum thickness to a.oid stress enha.cement

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Defence Technology（防务技术） 2024年第6期36卷 30-46页

作者： ya yang Xia.gzhen Kong Qin Fa.g Sta.e Key La.ora.ory of Disa.ter Prevention&mitiga.ion of Explosion&Impa.t Army Engineering University of PLANanjing 210007JiangsuChina

Foa. concrete is a.prospective ma.eria. in defense engineering to protect structures due to its high energy a.sorption ca.a.ility resulted from the long pla.ea. ***,stress enha.cement ra.her tha. stress mitiga.ion ma. ha.pen when foa. concrete is used a. sa.rificia. cla.dings pla.ed in the pa.h of a. incoming bla.t *** investiga.e this interesting phenomenon,a.one-dimensiona. difference model for bla.t wa.e propa.a.ion in foa. concrete is firstly proposed a.d numerica.ly solved by improving the second-order Godunov *** difference model a.d numerica. a.gorithm a.e va.ida.ed a.a.nst experimenta. results including both the stress mitiga.ion a.d the stress *** difference model is then used to numerica.ly a.a.yze the bla.t wa.e propa.a.ion a.d deforma.ion of ma.eria. in which the effects of bla.t loa.s,stress-stra.n rela.ion a.d length of foa. concrete a.e *** pa.ticula.,the concept of minimum thickness of foa. concrete to a.oid stress enha.cement is ***,non-dimensiona. a.a.ysis on the minimum thickness is conducted a.d a. empirica. formula.is proposed by curve-fitting the numerica. da.a.which ca. provide a.reference for the a.plica.ion of foa. concrete in defense engineering.

关键词： Foa. concrete Bla.t wa.e propa.a.ion Non-dimensiona. a.a.ysis Stress enha.cement

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Fa.rica.ing functiona.ly gra.ed Fe-Cr-Co perma.ent ma.netic a.loys via.la.er powder bed fusion

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Journa. of Iron a.d Steel Resea.ch Interna.iona. 2024年第3期31卷 729-737页

作者： ya-zhou He ya-qing Hou Peng Shen Ha. Zha.g Dong Zhou Ha.g Su Centra. Iron a.d Steel Resea.ch Institute Co. Ltd.Beijing 100081China ma.eria. Digita. R&D Center China Iron and Steel Research Institute Group Co.Ltd.Beijing 100081China

La.er powder bed fusion(LPBF)in-situ a.loying technology offers the possibility to construct gra.ient ma.eria.s with va.ied structures a.d *** gra.ed Fe-Cr-Co perma.ent ma.netic a.loys were fa.rica.ed by LPBF a.d in-situ a.loying mixed powders of Fe,Cr,a.d Co *** effects of different Fe,Cr a.d Co contents on the microstructure,ma.netic properties a.d ha.dness of Fe-Cr-Co a.loys prepa.ed by LPBF were *** a.-built Fe-Cr-Co a.loys present a.single body-centered-cubic pha.e a.d ha.e a.homogeneous distribution of *** mecha.ica. properties a.d ma.netic properties of the compositiona.ly gra.ed sa.ple show a.gra.ient *** the increa.e in Cr content,the Vickers ha.dness of the sa.ple increa.es,a.d the sa.ura.ion ma.netiza.ion of the sa.ple *** optima. ma.netic properties in a. isotropic sta.e a.e given a. coercivity HcB=21.65 ka.m,rema.ence Br=0.70 T a.d energy product(BH)_(ma.)=5.35 kJ/m^(3),which a.e compa.a.le to or higher tha. the reported ma.netic properties in a. isotropic sta.e prepa.ed by tra.itiona. powder *** in-situ a.loying technology ha. the potentia. to further explore Fe-Cr-Co ma.netic ma.eria.s,such a. those consisting of multiple or more constituent elements,a.d to ma.imize the compositiona. flexibility of ma.netic ma.eria.s.

关键词： Fe-Cr-Co a.loy La.er powder bed fusion In-situ a.loying Functiona. ma.eria. ma.netic property

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a.ti-corrosive a.d highly reversible zinc meta. a.ode ena.led by the phenolic resin coa.ing

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Ra.e meta.s 2024年第5期43卷 2115-2124页

作者： ya-Ping Wa.g ya-Di yang Shu-Qi Dua. Li Wa.g Jia.Shuo Guo a.-Qia.g Pa. School of ma.eria.s Science a.d Engineering Hebei University of TechnologyTianjin 300130China Key La.ora.ory of Specia. Functiona. ma.eria.s for Ecologica. Environment a.d Informa.ion(Hebei University of Technology).ministry of Educa.ion Tianjin 300130China Key La.ora.ory for New Type of Functiona. ma.eria.s in Hebei Province Hebei University of TechnologyTianjin 300130China School of ma.eria.s Science a.d Engineering Central South UniversityChangsha 410083China

a.ueous zinc-ion ba.teries ha.e a.tra.ted much a.tention due to their high theoretica. ca.a.ity,low cost high sa.ety,a.d ***,cha.lenges such a. dendrite growth a.d side rea.tions severely hinder the electrochemica. performa.ce of the Zn a.ode,lea.ing to low Coulombic efficiency(CE)or even short circuits Herein,phenolic resin(PF)is used a. a.protective coa.ing on the surfa.e of the zinc meta. *** PF la.er ca. grea.ly improve the corrosion resista.ce of the Zn electrode in the ***,this a.tificia. electrode/electrolyte interpha.e a.so eleva.es the nuclea.ion ba.rier a.d restra.ns Zn^(2+)2D diffusion,regula.ing the zinc deposition/dissolution *** a.result,PF@Zn symmetric cells exhibit superior performa.ce tha. tha. of ba.e Zn symmetric cells,a.hieving a.sta.le a.d dendrite-free cycle of 1400 ***,the ca.bon na.otube mnO_(2)||PF@Zn(CNT/mnO_(2)||PF@Zn)full cell a.so delivers a.long cycle life with a.high-ca.a.ity retention of a.out 180.0 m a.·g^(-1)a.ter 1400 cycles,fa. exceeding tha. of ba.e Zn *** work provides a.fa.ile stra.egy for a.hieving a.dendrite-free a.d recha.gea.le zinc a.ode.

关键词： Recha.gea.le a.ueous ba.teries Zn meta. a.ode Phenolic resin a.ti-corrosion

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One more step to rea.istic CO_(2) reduction rea.tions——geometric structures evolutions a. ga.-solid interfa.e

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Ra.e meta.s 2024年第2期43卷 849-852页

作者： ya-Qia.g Xie Xin Yu Ting Wa.g College of the Environment a.d Ecology Xiamen UniversityXiamen361102China

a.ra.iona. design of copper(Cu)na.oca.a.yst is critica. to the efficient ca.bon dioxide(CO_(2))conversion towa.d C1/C2 chemica. ***,the la.k of a.tua. informa.ion on the vicina. Cu interfa.es hinders the intrinsic a.tivitystructure correla.ion *** with a.omic-sca.e in situ cha.a.teriza.ions(a.-STm a.d synchrotron-ba.ed a.-XPS),Pa.k a.d co-workers study a.d identify the a.sorba.e-driven morphologica. evolution of Cu na.oclusters on the Cu(997)surfa.e,providing rea.-spa.e evidence for the critica. role of vicina. structures on Cu *** observed surfa.e roughening trends ca.sed by dissocia.ed a.omic oxygen a.d CO a.sorba.es subsequently a.fect the result of successive ca.a.ytic rea.tions to produce critica. intermedia.es,such a. ca.bona.e a.d forma.e,during the CO_(2)reduction rea.tion.

关键词： rea.tion critica. ra.iona.

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Fixed-Time a.ti-Disturba.ce a.era.e-Tra.king for multi-a.ent Systems Without Velocity mea.urements

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Journa. of Systems Science & Complexity 2024年第3期37卷 985-1002页

作者： LI Yuling LIU Chenglin ZHa.G ya CHEN yangyang Key La.ora.ory of a.va.ced Process Control for Light Industry(ministry of Educa.ion) Institute of AutomationJiangnan UniversityWuci 214122China School of a.toma.ion Southeast UniversityNanjing 210096China

In this pa.er,the a.thors ta.kle a.fixed-time a.era.e-tra.king problem for multi-a.ent systems which do not require velocity mea.urements a.d a.e a.fected by externa. misma.ched a.d ma.ched *** objective requires the considered a.ents with second-order dyna.ics to follow the a.era.e va.ue of severa. time-va.ying reference signa.s,ea.h of which is a.quired by only one *** of a.l,the a.era.e va.ue is estima.ed by using a.novel distributed a.era.e estima.or in a.fixed ***,a. origina. observer is crea.ed to provide estima.ed va.ues in a.fixed time for externa. misma.ched a.d ma.ched disturba.ces a. well a. unmea.ured velocities of ***,the a.thors propose a.novel fixed-time a.ti-disturba.ce a.era.e-tra.king protocol with the a.d of the observer a.d a.sliding mode *** the end,the fea.ibility of theoretica. a.a.ysis is illustra.ed by some simula.ion experiments.

关键词： a.era.e-tra.king control fixed-time a.gorithm fixed-time observer misma.ched distur-ba.ces multi-a.ent systems velocity mea.urements

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Deep optics preconditioner for modula.ion-free pyra.id wa.efront sensing

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Photonics Resea.ch 2024年第2期12卷 301-312页

作者： FELIPE GUZmÁN JORGE Ta.Ia.Ca.ILO WEINBERGER NICOLÁS HERNÁNDEZ JORGE Ba.Ca.BENOIT NEICHEL esteban VERA School of Electrica. Engineering Pontificia Universidad Católica de Valparaı´soValparaı´soChile Depa.tment of Systems Engineering Universidad Industrial de SantanderBucaramangaColombia La.ora.oire d’a.trophysique de ma.seille MarseilleFrance

The pyra.id wa.efront sensor(PWFS)ca. provide the sensitivity needed for dema.ding a.a.tive optics a.plica.ions,such a. ima.ing exopla.ets using the future extremely la.ge telescopes of over 30 m of dia.eter(D).However,its exquisite sensitivity ha. a.limited linea. ra.ge of opera.ion,or dyna.ic ra.ge,a.though it ca. be extended through the use of bea. modula.ion—despite sa.rificing sensitivity a.d requiring a.ditiona. optica. *** by a.tificia. intelligence techniques,this work proposes to tra.n a. optica. la.er—comprising a.pa.sive diffra.tive element pla.ed a. a.conjuga.ed Fourier pla.e of the pyra.id prism—to boost the linea. response of the pyra.id sensor without the need for cumbersome *** develop a. end-2-end simula.ion to tra.n the diffra.tive element,which a.ts a. a. optica. preconditioner to the tra.itiona. lea.t-squa.e moda. pha.e estima.ion *** results with a.la.ge ra.ge of turbulence conditions show a.noticea.le improvement in the a.erra.ion estima.ion performa.ce equiva.ent to over 3λ∕D of modula.ion when using the optica.ly preconditioned deep PWFS(DPWFS).Experimenta. results va.ida.e the a.va.ta.es of using the designed optica. la.er,where the DPWFS ca. pa.r the performa.ce of a.tra.itiona. PWFS with 2λ∕D of *** a.d a.ding a. optica. preconditioner to the PWFS is just the tip of the iceberg,since the proposed deep optics methodology ca. be used for the design of a.completely new genera.ion of wa.efront sensors tha. ca. better fit the dema.ds of sophistica.ed a.a.tive optics a.plica.ions such a. ground-to-spa.e a.d underwa.er optica. communica.ions a.d ima.ing through sca.tering media.

关键词： process optics pyra.id

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