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“第十届中国钢铁年会”暨“第六届宝钢学术年会”

作者： loo chin eng Penny Gareth Matthews Leanne Ellis Benjamin Centre for Ironmaking Materials Research Discipline of Chemical Engineering School of Engineering Faculty of Engineering & Built Environment The University of Newcastle

Although softening/melting tests are widely used to assess ferrous material properties in the cohesive zone of a blast furnace,there is little understanding of the mechanisms causing the softened bed to densify.Quenched beds of three acid feed materials–a porous hematite goethite lump（PHGL）,a dense high silica lump（DHSL）and a high silica pellet（HSP）-were used to provide information on the role of silica and porosity on softening and melting behavior.Reduction of all three materials is topochemical,resulting in the formation of a distinct metallic iron shell and a wustite core.The efficiency of the wustite to iron reduction process is dependent on the penetration of reducing gas through the shell and the structure of the core.This is enhanced for samples with higher porosity and low silica content,which minimizes the formation of fayalite,a low melting compound formed from the reaction of silica with iron oxide.With higher levels of fayalite,the core can become sealed off from the reducing gases,leading to greater levels of wustite that must undergo direct reduction at temperatures above 1000℃.Furthermore,the presence of fayalite in significant quantities can act as a lubricant between particles,facilitating sliding and bed densification further reducing bed permeability and reduction efficiency.For the three materials tested,the higher porosity and lower silica content of the PHGL improved the low temperature reducibility of the sample relative to DHSL and HSP,leaving much less wustite for direct reduction.This study also shows that increasing the reduction rate of wustite to iron also has two other benefits.Firstly,with higher reducibility,fayalite levels decrease because iron oxide,not metallic iron,is required in its formation.Secondly,the level of exuded liquid wustite in inter-particle pores decreases which will improve cohesive zone permeability.These results suggest that as a complementary feed to basic sinter,a porous low-silica lump such as PHGL should yield better performance in a blast furnace.

关键词： blast furnace cohesive zone softening and melting bed properties

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铁矿石烧结中混合料特性对火焰烽面与烧结性能的影响机理研究

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化工学报 2019年第8期70卷 3177-3187页

作者：赵加佩 chin eng loo 周昊周明煕王甫袁金良宁波大学海运学院浙江宁波315832 Iron Ore Utilisation Consultant NewcastleNew South Wales 2280Australia 浙江大学能源清洁利用国家重点实验室浙江杭州310027

通过中试规模烧结杯试验和综合烧结模型,将返矿平衡和非平衡条件相结合,研究了混合料特性(烧结碱度、焦炭和水分添加量)对火焰烽面特性和烧结性能的影响机理。模拟研究涉及多种烧结条件下的125个烧结杯工况。为揭示火焰烽面区域中熔体... 详细信息

通过中试规模烧结杯试验和综合烧结模型,将返矿平衡和非平衡条件相结合,研究了混合料特性(烧结碱度、焦炭和水分添加量)对火焰烽面特性和烧结性能的影响机理。模拟研究涉及多种烧结条件下的125个烧结杯工况。为揭示火焰烽面区域中熔体生成与凝固行为,使用FactSage软件进行化学热力学模拟并建立了更完善的熔化和凝固子模型。模拟与试验研究表明,随着碱度和焦炭添加量的变化,火焰烽面速度、成品率、焦比和利用系数会出现局部最大或最小值。在本文烧结条件下,最大利用系数工况为碱度2.0、水分7.7%、焦炭6.4%。最小焦比工况为碱度2.0、水分6.5%、焦炭6.4%。最小焦比和最大利用系数的条件并不相同,而最终烧结操作取决于每个烧结厂的控制目标。

关键词：焦炭燃烧火焰烽面填充床传热数值模拟

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Renminbi Appreciation and china's Industrial Upgrading

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china & World Economy 2022年第3期30卷 1-22页

作者： chin-Yoong Wong Yoke-Kee eng Department of Economics Faculty of Business&FinanceUniversiti Tunku Abdul RahmanMalaysia Faculty of Business&Finance Universiti Tunku Abdul RahmanMalaysia

To identify the macroeconomic environment that has enabled china's industrial upgrading during a period of persistent renminbi appreciation,we construct a two-country New Keynesian model of industrial upgrading with a global production network,endogenous firm entry,and a directed quality frontier.We show that renminbi appreciation promotes industrial upgrading without hurting real economic growth in the longer run.This holds true especially through four channels.First,the quality threshold for firm entry is lower to allow for more firms participation and thus greater product varieties(quality threshold channel).Second,upstream skill-based production uses more imported inputs of higher quality(imported input channel).Third,there is substantial global demand towards the exports of high-quality inputs(global demand channel).Fourth,domestic inputs are competing against imported inputs to broaden the scope for competition in the upstream product market to incentivize quality upgrading(scope for competition channel).

关键词： endogenous firm entry global production sharing industrial upgrading renminbi appreciation structural reform

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A Mini Review: Can Graphene Be a Novel Material for Perovskite Solar Cell Applications?

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Nano-Micro Letters 2018年第2期10卷 92-103页

作者： eng Liang Lim Chi chin Yap Mohammad Hafizuddin Hj Jumali Mohd Asri Mat Teridi chin Hoong Teh School of Applied Physics Faculty of Science and Technology Universiti Kebangsaan Malaysia Solar Energy Research Institute Universiti Kebangsaan Malaysia ASASI Pintar Program Pusat Permata Pintar NegaraUniversiti Kebangsaan Malaysia

Perovskite solar cells(PSCs) have raised research interest in scientific community because their power conversion efficiency is comparable to that of traditional commercial solar cells(i.e., amorphous Si, GaAs,and CdTe). Apart from that, PSCs are lightweight, are flexible, and have low production costs. Recently, graphene has been used as a novel material for PSC applications due to its excellent optical, electrical, and mechanical properties. The hydrophobic nature of graphene surface can provide protection against air moisture from the surrounding medium, which can improve the lifetime of devices. Herein, we review recent developments in the use of graphene for PSC applications as a conductive electrode,carrier transporting material, and stabilizer material. By exploring the application of graphene in PSCs, a new class of strategies can be developed to improve the device performance and stability before it can be commercialized in the photovoltaic market in the near future.

关键词： Perovskite solar cells Graphene Conductive electrode Carrier transporting material Stabilizer material Performance and stability

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A rare cause of acute abdomen–Spontaneous rectus sheath hematoma

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Asian Pacific Journal of Tropical Biomedicine 2016年第10期6卷 892-895页

作者： Hock chin Chong Feng Yih Chai Yew eng Tan Sophia Si Ling Heng Siti Asilah Mohd Desa Department of Surgery Hospital Queen Elizabeth Department of Surgery Hospital Keningau

Spontaneous rectus sheath hematoma(SRSH) is a rare entity that mimics acute abdomen.Rectus sheath hematoma is the accumulation of blood in rectus sheath due to muscle or epigastric vessel injury. However, SRSH without a trauma or anticoagulation is rare. It frequently mimics acute abdomen and it may lead to misdiagnosis and unnecessary laparotomy. In this article, we described two cases of SRSH with their diagnostic and therapeutic strategy. Both of our patients in report were neither consumed antiplatelet nor coagulopathy. They both had abdominal muscle straining before their symptoms presentation. We hypothesized that the SRSH may be induced by rectus muscle injury secondary to inappropriate straining or posture. To diagnose SRSH, clinical findings are important but radiologic imaging such as computed tomography, can be diagnostic. In expanding SRSH, percutaneous arterial embolization of epigastric artery is useful to secure the bleeding. If embolization is not feasible, surgical exploration hemostasis is curative. In non-expanding SRSH, it can be managed nonoperatively. SRSH is an important initial differential for acute abdomen. Radiologic imaging helps in diagnosis.Stable SRSH can be managed conservatively with good outcome.

关键词： Rectus muscle injury Epigastric vessel Spontaneous Acute abdomen

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Secretive derived from hypoxia preconditioned mesenchymal stem cells promote cartilage regeneration and mitigate joint inflammation via extracellular vesicles

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Bioactive Materials 2023年第9期27卷 98-112页

作者： Yanmeng Yang Yingnan Wu Dahou Yang Shu Hui Neo Nurul Dinah Kadir Doreen Goh Jian Xiong Tan Vinitha Denslin eng Hin Lee Zheng Yang Department of Orthopaedic Surgery Yong Loo Lin School of MedicineNational University of SingaporeSingapore NUS Tissue engineering Program Life Sciences InstituteNational University of SingaporeSingapore Critical Analytics for Manufacturing Personalised-Medicine Singapore-MIT Alliance for Research and TechnologySingapore

Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the physiologic environment of MSCs, has great potential to enhance MSCs paracrine therapeutic effect. In our study, the paracrine effects of secretome derived from MSCs preconditioned in normoxia and hypoxia was compared through both in vitro functional assays and an in vivo rat osteochondral defect model. Specifically, the paracrine effect of total EVs were compared to that of soluble factors to characterize the predominant active components in the hypoxic secretome. We demonstrated that hypoxia conditioned medium, as well as the corresponding EVs, at a relatively low dosage, were efficient in promoting the repair of critical-sized osteochondral defects and mitigated the joint inflammation in a rat osteochondral defect model, relative to their normoxia counterpart. In vitro functional test shows enhancement through chondrocyte proliferation, migration, and matrix deposition, while inhibit IL-1β-induced chondrocytes senescence, inflammation, matrix degradation, and pro-inflammatory macrophage activity. Multiple functional proteins, as well as a change in EVs’ size profile, with enrichment of specific EV-miRNAs were detected with hypoxia preconditioning, implicating complex molecular pathways involved in hypoxia pre-conditioned MSCs secretome generated cartilage regeneration.

关键词： Hypoxia preconditioned MSCs Secretome Extracellular vesicles Cartilage regeneration Joint inflammation

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From blood to brain:amoeboid microglial cell,a nascent macrophage and its functions in developing brain

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Acta Pharmacologica Sinica 2007年第8期28卷 1087-1096页

作者： Charanjit KAUR S Thameem DHEEN eng-ang LING Department of Anatomy Yong loo Lin School of Medicine National University of Singapore117597Singapore

Amoeboid microglial cells(AMC)in the developing brain are active macrophages.The macrophagic nature of these cells has been demonstrated by many methods,such as the localization of various hydrolytic enzymes and the presence of comple-ment type 3 surface receptors in them.More importantly is the direct visualizationof these cells engaged in the phagocytosis of degenerating cells at the ultrastruc-tural level.Further evidence of them being active macrophages is the avid inter-nalization of tracers administered by the intravenous or intraperitoneal routes indeveloping rats.The potential involvement of AMC in immune functions is sup-ported by the induced expression of major histocompatibility complex class I andII antigens on them when challenged by lipopolysaccharide or interferon-γ.Im-munosuppressive drugs,such as glucocorticoids and immune function-enhanc-ing drugs like melatonin,affect the expression of surface receptors and antigensand the release of cytokines by AMC.Recent studies in our laboratory haveshown the expression of insulin-like growth factors,endothelins,2',3'-cyclic nucle-otide 3'-phosphodiesterase,and N-methyl-D-asparate receptors.This along withthe release of chemokines,such as stromal derived factor-la and monocytechemoattractant protein-1,suggests multiple functional roles of AMC in earlybrain development.

关键词： developing brain amoeboid microglial cells functions

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铁矿烧结的研究成就和未来需求

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现代冶金（内蒙古） 2007年第3期 5-8,16页

作者： chin eng loo[澳大利亚] 韩淑霞(译) 邬虎林(校)

众所周知铁矿烧结技术已取得了重大进步。从实验室烧结杯试验到工业试验，将烧结过程分为几个阶段来研究，首先通过烧结杯试验获得了其操作参数及其相互关系，还有烧结的制粒也在做广泛地研究。最近几年烧结过程的燃烧带是科技工作者研... 详细信息

众所周知铁矿烧结技术已取得了重大进步。从实验室烧结杯试验到工业试验，将烧结过程分为几个阶段来研究，首先通过烧结杯试验获得了其操作参数及其相互关系，还有烧结的制粒也在做广泛地研究。最近几年烧结过程的燃烧带是科技工作者研究的焦点项目。其铁矿石的熔化形成过程很重要，因此研究混合料中矿石相互作用是必要的。烧结研究的最终目标是要掌握烧结过程的最基本特性，这样才能建立起基础的烧结模型。关于烧结矿质量的研究内容是，烧结矿的粉化和还原性。

关键词：铁矿烧结烧结杯试验烧结矿质量烧结过程科技工作者烧结技术工业试验操作参数

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Hypoxia and the developing brain： factors underlying cell damage

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解剖学杂志 2009年第3期32卷 281-285页

作者： Charanjit Kaur Ling eng Ang Department of Anatomy Yong Loo Lin School of Medicine Blk MDIO 4 Medical DriveNational University of Singapore Singapore 117597

Structural and functional integrity of brain function depends on a regular oxygen supply. The developing brain is extremely sensitive to oxygen deprivation or hypoxia which affects the normal development and maturatio... 详细信息

关键词：组织缺氧大脑细胞损害外科医学

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Studying neurological disorders using induced pluripotent stem cells and optogenetics

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Neural Regeneration Research 2015年第11期10卷 1720-1722页

作者： Eunice W.M.chin Eyleen L.K.Goh Program in Neuroscience and Behavioral Disorders Duke-NUS Graduate Medical School Singapore NUS Graduate School for Integrative Singapore Sciences and Engineering National University of Singapore Department of Physiology Yong Loo Lin School of Medicine National University of Singapore KK Research Center KK Women’s and Children’s HospitalSingapore

Neurological disorders are amongst the most widely studied human aliments.Yet,they are also one of the most poorly understood.Although most of these disorders are polygenic,genotype still plays an important role in their etiologies.For example,in schizophrenia and autism spectrum disorders,there is a 40-60%concordance rate in monozygotic twins,with 60-90%heritability（Burmeister et al.,2008）.However,the mechanisms by which multiple genes and their genomic variations influence the phenotypes of the disorders remain to be understood. The complexities of the disorders are tur- ther compounded by the individual rarity of the genomic variations and their variable penetrance （Cook and Scherer, 2008）. Thus, conventional disease modeling, such as gene knockout in cells or in animals, to attain the desired disease genotype may not be the most suitable platform for tackling most neurological disorders.

关键词： PSCs cell stem Studying neurological disorders using induced pluripotent stem cells and optogenetics

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