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Analysis of the Spatial Distribution Characteristics of Abnormal Bone Density in Male Long-Distance Runners from Different Regions in China

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Open Journal of Epidemiology 2021年第1期11卷 80-91页

作者： longxing fan Wenjie Zhang Huanhuan Cui Yanqing Liu Ziquan Liu Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety College of Chemistry Fuzhou University Fuzhou China Tianjin Center for Disease Control and Prevention Tianjin China Institute of Disaster Medicine Tianjin University Tianjin China

Objective: To investigate the occurrence pattern of abnormal bone density in male long-distance runners from several different regions of China, and provide a basis for elucidating the influences of geo-environmental differences on bone density. Methods: We employed a set of well-designed exclusion-inclusion criteria to recruit study subjects, in which compounding factors were managed and regional environmental traits were fully incorporated. WHO (World Health Organization) criteria for the diagnosis of osteoporosis were then used to examine the subjects to determine occurrence of abnormal bone density. The resulting data were analyzed using methods of spatial statistics, which included several approaches, such as spatial autocorrelation, hot spot analysis, and Geodetector Software analysis, to depict and analyze the spatial distribution of abnormal bone density in male athletes from different regions in China, thereby investigating the influences of geo-environmental factors (e.g., temperature, humidity, and altitude) on bone density. Results: A total of 685 subjects were effectively examined in this study, including 486 with normal bone density, 185 with osteopenia, and 14 with osteoporosis. Spatial distribution analysis revealed that the distribution of subjects with abnormal bone density overall exhibited a pattern indicating that the level of abnormal bone density in the eastern regions was higher than that in the western regions and that the levels of abnormal bone density in the southern and northern regions were higher than that in the middle regions. Spatial autocorrelation analysis revealed a Moran’s I = 0.136, Z-score = 1.114, and P value = 0.265 and indicated that the athletes with abnormal bone density were randomly distributed in each region. Hot spot analysis revealed that Tibet and Qinghai displayed distributions of cold spots. Geodetector Software analysis yielded a Q<

关键词： Spatial Epidemiology Regions Athletes Bone Density

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Investigation on Low Hemoglobin and Ascaris Infection among Primary and Secondary School Students in Hohhot

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Open Journal of Epidemiology 2020年第2期10卷 115-124页

作者： Wentao Liu Bowei Dong longxing fan Jun Liu Bao’an Ning Ying Liu School of Public Health Inner Mongolia Medical University Hohhot China Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety College of Chemistry Fuzhou University Fuzhou China The 291st Hospital of the Chinese People’s Liberation Army Baotou China Tianjin Institute of Environmental and Operational Medicine Tianjin China

Introduction: Anemia and Ascaris infection are important indicators to reflect the health status of students. In this study, by investigating the current situation of low hemoglobin and positive rate of Ascaris eggs of primary and secondary school students in Hohhot, the health status of local primary and secondary school students is actually reflected. Objectives: To understand the prevalence of Low Hemoglobin and Ascaris infection among primary and secondary school students in Hohhot in 2015 and to give some suggestions on the health status of primary and secondary school students in Hohhot. Study Design: This project uses a cross-sectional study to investigate the distribution of disease and health status of primary and middle school students in Hohhot at a specific time, and to provide a clue to the cause of the hypothesis test. Methods: A stratified cluster random sampling method was used to select 4 districts, 4 counties and 1 flag in Hohhot, a total of 36 primary and secondary schools for sample survey. Cyanine HiCN and smear method is to detect hemoglobin and ascaris eggs positive. Results: In 2015, the positive rate of low hemoglobin in primary and secondary school students was 21.45% in urban and rural areas, 33.17% in urban and rural areas, 43.69% in rural areas, 13.59% in ascaris eggs, 10.69% in urban and rural areas, 7.81% in rural areas. There are geographical differences and gender differences between cities, urban-rural junctions and rural areas (p Conclusion: The prevalence of low hemoglobin in primary and secondary school students in Hohhot is high in rural areas. The detection rate of ascaris egg positive rate in the city is high. Monitoring, publicity and education should continue to be strengthened.

关键词： Primary and Secondary School Students Low Hemoglobin Ascaris Infection Positive Rate

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Nutritional Status of Students in Poverty-Stricken Areas

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Open Journal of Epidemiology 2020年第2期10卷 91-99页

作者： Bowei Dong Wentao Liu Jun Liu longxing fan Hanxuan Yun Xuejiao Gai Zhenyu Han Zhuangzhi Song Chunxia Cui Ying Liu School of Public Health Inner Mongolia Medical University Hohhot China Tianjin Institute of Environmental & Operational Medicine Tianjin China Chinese PLA No.969 Hospital Baotou China Ministry of Education Key Laboratory of Analysis and Detection for Food Safety College of Chemistry Fuzhou University Fuzhou China Inner Mongolia Center for Disease Control and Prevention Hohhot China

Objective: In this study, we aim to understand the nutritional status of students in poverty-stricken areas of Inner Mongolia and their links with academic performance and to provide a scientific basis for the designated nutrition intervention and health education in students. Methods: In Zhalaiteqi County students’ physical health survey data and learning achievement scores from 2012 to 2013 were selected as research data, and the nutritional status of the students was judged by statistical analysis of physical data. Results: The malnutrition rate was 22.21%, the overweight rate was 6.0%, and the obesity rate was 3.81% in 2012. The detection rate of the male normal group was 80.22%, and the detection rate of the female normal group was 75.63%. The difference was statistically significant (χ2 = 27.036 P Conclusion: The nutritional status of students in poverty-stricken areas in Inner Mongolia cannot be neglected. Weight loss and obesity have a negative impact on students’ academic performance. Effective measures should be taken to control the present situation.

关键词： Nutritional Status Poor Learning Achievement Results Evaluation Anemia

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响应面法优化组成型壳聚糖酶酶解条件

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中国酿造 2020年第1期39卷 165-169页

作者：赵华樊龙星张朝正天津科技大学生物工程学院工业发酵微生物教育部重点实验室天津市工业微生物重点实验室天津市微生物代谢与发酵过程控制技术工程中心

以壳聚糖为原料,通过蜡状芽孢杆菌(Bacillus cereus)发酵所得壳聚糖酶水解壳聚糖产生壳寡糖,对酶解pH、温度、底物浓度和时间分别进行单因素试验,并在此基础上,通过响应面法研究这4种因素对壳寡糖产量的影响,优化酶解条件。结果表明,壳... 详细信息

以壳聚糖为原料,通过蜡状芽孢杆菌(Bacillus cereus)发酵所得壳聚糖酶水解壳聚糖产生壳寡糖,对酶解pH、温度、底物浓度和时间分别进行单因素试验,并在此基础上,通过响应面法研究这4种因素对壳寡糖产量的影响,优化酶解条件。结果表明,壳聚糖酶酶解的最佳条件为pH值5.6,酶解温度53℃,壳聚糖质量分数2.09%,酶解时间157 min。在该优化条件下,壳寡糖的浓度为35.73μmol/mL,与模型预测值35.476μmol/mL接近,则该模型可用于优化壳聚糖酶酶解条件。

关键词：蜡状芽孢杆菌壳聚糖酶响应面法酶解条件优化

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山药发酵酒的制备工艺优化

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食品工业 2020年第7期41卷 34-36页

作者：樊龙星张朝正赵华工业发酵微生物教育部重点实验室天津市工业微生物重点实验室天津市微生物代谢与发酵过程控制技术工程中心天津科技大学生物工程学院天津300457

为优化山药发酵酒的制备工艺,以液化和糖化后的山药为原料,探究酵母接种量,温度和发酵时间3个因素对发酵作用的影响。以酒精度为主要指标,在单因素试验的基础上,进行正交试验,最终确定最佳发酵条件为:酵母接种量0.2%,温度30℃,发酵时间2... 详细信息

为优化山药发酵酒的制备工艺,以液化和糖化后的山药为原料,探究酵母接种量,温度和发酵时间3个因素对发酵作用的影响。以酒精度为主要指标,在单因素试验的基础上,进行正交试验,最终确定最佳发酵条件为:酵母接种量0.2%,温度30℃,发酵时间20 h,最终发酵所得酒精度为3.96%vol,为制备混合饮料奠定基础。

关键词：液化糖化山药单因素试验正交试验

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呼和浩特市城乡汉族中小学生龋齿患病情况

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中国学校卫生 2016年第12期37卷 1851-1855页

作者：刘颖范龙兴曲晓辰乌恩琦段生云内蒙古医科大学公共卫生学院呼和浩特010110

目的了解2015年呼和浩特地区城乡汉族中小学生龋齿患病流行现状,为当地制定中小学生防龋策略提供科学依据。方法采用分层随机整群抽样方法在呼和浩特4个城区和5个旗县每个区域随机抽取2所小学和2所中学,每所学校的各个年级随机抽取1... 详细信息

目的了解2015年呼和浩特地区城乡汉族中小学生龋齿患病流行现状,为当地制定中小学生防龋策略提供科学依据。方法采用分层随机整群抽样方法在呼和浩特4个城区和5个旗县每个区域随机抽取2所小学和2所中学,每所学校的各个年级随机抽取1个班的汉族学生为调查对象。以龋患率、龋失补构成比、龋均为调查指标,并与1995年呼和浩特和2005年全国中小学生龋齿患病资料进行比较分析。结果本次调查受检7 888人,总龋患2 514人,总龋患率为31.87%,龋失补总牙数5 674颗,总龋均0.72。与1995年相比,男、女生及城乡学生总龋齿患病率均下降（χ^2值分别为229.440,260.295,29.179,12.016,P值均〈0.01）。与2005年全国中小学生龋齿患病资料差异不大。结论呼和浩特地区城乡汉族中小学生龋患情况有所好转,但当地政府和相关部门仍然要加强学生和家长防治龋齿的宣传教育工作。

关键词：龋齿患病率中小学生卫生保健服务

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The JAK-STAT pathway:from structural biology to cytokine engineering

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Signal Transduction and Targeted Therapy 2024年第9期9卷 3870-3906页

作者： You Lv Jianxun Qi Jeffrey JBabon longxing Cao Guohuang fan Jiajia Lang Jin Zhang Pengbing Mi Bostjan Kobe Faming Wang Center for Molecular Biosciences and Non-communicable Diseases Research Xi’an University of Science and TechnologyXi’anShaanxi 710054China Xi’an Amazinggene Co. LtdXi’anShaanxi 710026China CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100080China The Walter and Eliza Hall Institute of Medical Research Parkville VIC 3052Australia School of Life Sciences Westlake UniversityHangzhouZhejiang 310024China Immunophage Biotech Co. LtdNo.10 Lv Zhou Huan RoadShanghai 201112China School of Pharmaceutical Science Hengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China School of Chemistry and Molecular Biosciences Institute for Molecular Bioscience and Australian Infectious Diseases Research CentreUniversity of QueenslandBrisbaneQueensland 4072Australia

The Janus kinase-signal transducer and activator of transcription(JAK-STAT)pathway serves as a paradigm for signal transduction from the extracellular environment to the *** plays a pivotal role in physiological functions,such as hematopoiesis,immune balance,tissue homeostasis,and surveillance against *** of this pathway may lead to various disease conditions such as immune deficiencies,autoimmune diseases,hematologic disorders,and *** to its critical role in maintaining human health and involvement in disease,extensive studies have been conducted on this pathway,ranging from basic research to medical *** in the structural biology of this pathway have enabled us to gain insights into how the signaling cascade operates at the molecular level,laying the groundwork for therapeutic development targeting this *** strategies have been developed to restore its normal function,with promising therapeutic *** comprehension of these molecular mechanisms,combined with advances in protein engineering methodologies,has allowed us to engineer cytokines with tailored properties for targeted therapeutic applications,thereby enhancing their efficiency and *** this review,we outline the structural basis that governs key nodes in this pathway,offering a comprehensive overview of the signal transduction ***,we explore recent advances in cytokine engineering for therapeutic development in this pathway.

关键词： cytokine structural thereby

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基于统计分析的SoC定点硬件加速器字长设计

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固体电子学研究与进展 2007年第2期27卷 240-245,274页

作者：周凡时龙兴杨军东南大学国家专用集成电路系统工程技术研究中心南京210096

在由通用RISC处理器核和附加定点硬件加速器构成的定点SoC(System-on-Chip)芯片体系架构基础上,提出了一种新颖的基于统计分析的定点硬件加速器字长设计方法。该方法利用统计参数在数学层面上求解计算出满足不同信噪比要求下的最小字长... 详细信息

在由通用RISC处理器核和附加定点硬件加速器构成的定点SoC(System-on-Chip)芯片体系架构基础上,提出了一种新颖的基于统计分析的定点硬件加速器字长设计方法。该方法利用统计参数在数学层面上求解计算出满足不同信噪比要求下的最小字长,能有效地降低芯片面积、功耗和制作成本,从而在没有DSP协处理器的低成本RISC处理器核SoC芯片上运行高计算复杂度应用。

关键词：硬件加速器定点系统芯片信噪比统计分析

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航空发动机变几何涡轮增压性能研究

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北京航空航天大学学报 2017年第8期43卷 1523-1530页

作者：徐斌周帆杨世春田富刚谭龙兴北京航空航天大学交通科学与工程学院北京100083

提出了一种变几何涡轮增压器用于发动机高空恢复功率的方法,并对其调节规律和相关特性进行研究。依据涡轮流动模型,分析了相同工况下不同喷嘴环开度对涡轮增压器工作的影响。在GT-POWER中建立了变几何涡轮增压发动机模型,通过全高度下... 详细信息

提出了一种变几何涡轮增压器用于发动机高空恢复功率的方法,并对其调节规律和相关特性进行研究。依据涡轮流动模型,分析了相同工况下不同喷嘴环开度对涡轮增压器工作的影响。在GT-POWER中建立了变几何涡轮增压发动机模型,通过全高度下不同工况的仿真分析,验证了变几何涡轮增压发动机恢复海平面功率的应用。结果表明,匹配了变几何涡轮增压器的发动机能够显著提高发动机高空可调范围,其使用升限从5 km提升到了6 km,对变几何涡轮增压器应用于恢复功率与喷嘴环开度的调节规律具有指导意义。

关键词：航空活塞发动机变几何涡轮增压功率特性可调范围使用升限

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基于改进最小二乘法的焊缝直线提取研究

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热加工工艺 2018年第15期47卷 217-220,224页

作者：樊德金杨龙兴丁力梁栋江苏理工学院机械工程学院

针对焊缝直线提取精度低的问题,提出了一种改进的最小二乘法。先对焊缝图像进行图像处理,提取焊缝区域内的相关特征点集,然后在最小二乘法中引入多个参量,循环利用该改进的最小二乘法对点集进行直线拟合,得出最优的焊缝中心线。最后,讨... 详细信息

针对焊缝直线提取精度低的问题,提出了一种改进的最小二乘法。先对焊缝图像进行图像处理,提取焊缝区域内的相关特征点集,然后在最小二乘法中引入多个参量,循环利用该改进的最小二乘法对点集进行直线拟合,得出最优的焊缝中心线。最后,讨论了参量对于直线拟合的影响。结果表明,改进的最小二乘法能够有效地提取焊缝的特征直线,在焊缝跟踪方面能够达到高精度提取焊缝直线的要求。

关键词：图像处理焊缝中心线最小二乘法焊缝跟踪

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