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大豆分离蛋白聚集体及凝胶制品的研究进展

农产品加工 2019年第8期 71-74页

作者：李倩如熊瑶叶倩林嘉诺张龙涛郑宝东福建农林大学食品科学学院福建福州350002 中爱国际合作食品物质学与结构设计研究中心福建福州350002 福建省特种淀粉品质科学与加工技术重点实验室福建福州350002

大豆分离蛋白凝胶制品的品质调控一直是产业热点,大豆蛋白聚集体作为蛋白成胶前体,其作用机理一直被广泛研究。在综述大豆蛋白聚集及凝胶机理的基础上,进一步综述了大豆蛋白聚集对凝胶成品的影响,提出了探索未变性大豆蛋白对大豆蛋白凝... 详细信息

大豆分离蛋白凝胶制品的品质调控一直是产业热点,大豆蛋白聚集体作为蛋白成胶前体,其作用机理一直被广泛研究。在综述大豆蛋白聚集及凝胶机理的基础上,进一步综述了大豆蛋白聚集对凝胶成品的影响,提出了探索未变性大豆蛋白对大豆蛋白凝胶过程中物化性质的研究思路,对控制大豆蛋白凝胶形成过程、开发品质各异的大豆蛋白制品具有一定的参考价值。

关键词：大豆分离蛋白聚集凝胶变性

30nm PMOS器件总剂量辐照实验与仿真

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现代应用物理 2022年第1期13卷 125-128,179页

作者：张宏涛曹艳荣王敏任晨张龙涛吕玲郑雪峰马晓华西安电子科技大学机电工程学院西安710071 宽禁带半导体技术国家重点学科实验室西安710071

使用Silvaco TCAD软件建立PMOS器件模型,仿真模拟得到了PMOS器件γ射线总剂量效应,提取了氧化层及界面处陷阱电荷共同影响后器件的电学参数并验证了退化程度。仿真结果表明,PMOS器件沟道越短,有效沟道长度占比总沟道长度就越少,器件退... 详细信息

使用Silvaco TCAD软件建立PMOS器件模型,仿真模拟得到了PMOS器件γ射线总剂量效应,提取了氧化层及界面处陷阱电荷共同影响后器件的电学参数并验证了退化程度。仿真结果表明,PMOS器件沟道越短,有效沟道长度占比总沟道长度就越少,器件退化加剧。开展了宽长比为500 nm/30 nm的30 nm PMOS器件的总剂量效应实验。实验表明,γ射线的持续辐照会使器件发生退化,阈值电压负向漂移,亚阈摆幅变化量增大。仿真结果与实验数据均表明,浅沟槽隔离氧化层陷阱电荷是造成器件退化的主要影响因素。

关键词： PMOS器件总剂量效应可靠性 Silvaco TCAD

纳米MOS器件场氧化层和栅氧化层电离总剂量效应仿真

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现代应用物理 2022年第1期13卷 172-179页

作者：任晨曹艳荣张龙涛吕航航马毛旦吕玲郑雪峰西安电子科技大学机电工程学院宽禁带半导体技术国家重点学科实验室西安710071

利用Silvaco TCAD软件,研究了电离总剂量(total ionizing dose,TID)效应对28 nm NMOSFET转移特性的影响。构建了28 nm NMOSFET 3维仿真模型,分3种情况探究了TID效应影响下,场氧化层和栅氧化层对NMOSFET的阈值电压、漏电流和跨导的影响... 详细信息

利用Silvaco TCAD软件,研究了电离总剂量(total ionizing dose,TID)效应对28 nm NMOSFET转移特性的影响。构建了28 nm NMOSFET 3维仿真模型,分3种情况探究了TID效应影响下,场氧化层和栅氧化层对NMOSFET的阈值电压、漏电流和跨导的影响。仿真结果表明,在TID效应影响下,28 nm NMOSFET场氧化层对器件阈值电压、漏电流和跨导的影响都明显大于栅氧化层,随着器件尺寸的减小,场氧化层在TID效应中对NMOSFET电学特性的影响较大。仿真结果为进一步探究NMOSFET的TID效应提供了参考。

关键词： TCAD仿真 NMOSFET 总剂量效应氧化层

The axisymmetric Rayleigh waves in a semi-infinite elastic solid

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Theoretical & Applied Mechanics Letters 2020年第2期10卷 120-124页

作者： Ji Wang Shaoyun Wang longtao Xie Yangyang zhang Lili Yuan Jianke Du Han zhang Piezoelectric Device Laboratory School of Mechanical Engineering and MechanicsNingbo UniversityNingbo315211 ZhejiangChina Noise and Vibration Laboratory Institute of AcousticsChinese Academy of Sciences100190 BeijingChina

It is well-known that Rayleigh wave,also known as surface acoustic wave(SAW),solutions in semiinfinite solids are plane waves with signatory properties like the distinct velocity and exponentially decaying deformation in the *** of Rayleigh waves are focused on the deformation and energy in the vicinity of surface of solids and less loss in the propagation.A generalized model of Rayleigh waves in axisymmetric mode is established and solutions are obtained with cylindrical *** is found that the Rayleigh waves also propagate in the axisymmetric mode with slow decay in radius,confirming the existence of surface acoustic waves is irrelevant to coordinate *** the other hand,the solutions can be treated as plane waves in regions far away from the ***,the particle trajectory of axisymmetric SAW is a line with constant slope rather than the signatory ellipse in Cartesian coordinate case.

关键词： Axisymmetric Rayleigh wave Solid Propagation Velocity

Crustal activities recorded incoral reefs in the northwestern South China Sea

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Chinese Science Bulletin 2006年第B12期51卷 89-94页

作者： ZHAN Wenhuan YAO Yantao zhang Zhiqiang SUN Zongxun ZHAN Meizhen SUN longtao LIU Zaifeng CAS Key Laboratory of Marginal Sea Geology South China Sea Institute of Oceanology Chinese Academy of Sciences Guangzhou 510301 China

Coral reefs in the northwest of South China Sea have recorded the information from not only the environmental variation but also the crustal activities there during their development. The main crustal activities correlated with the coral reef development include fault, seismic, and volcano activities, etc. The high-resolution spark seismic profiles in the northwestern South China Sea show that the fault activities in the coral reef region have been clearly recorded, and appear as neonatal faults incising reefs. Earthquakes in the coral reef region are rather intense, especially the two occurring on December, 31, 1994, and January, 10, 1995, around the southwest of Leizhou Peninsula, with the magnitude of 6.1 and 6.2, respectively. They have great influence on the growth of the local coral reefs. Quaternary volcanos are active in the northwestern South China Sea, especially around the southwest of Leizhou Peninsula, and they have obvious control of the coral reef development. Some submarine volcanoes form the substrates of coral reef, while a few emerge above the sea surface and form coral islands.

关键词：南海西北部海域珊瑚礁外壳活动性环境变化

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28nm MOSFET器件的单粒子效应

现代应用物理 2022年第1期13卷 116-124页

作者：张龙涛曹艳荣任晨马毛旦吕航航吕玲郑雪峰马晓华西安电子科技大学机电工程学院西安710071 宽禁带半导体技术国家重点学科实验室西安710071

利用SILVACO TCAD软件构建了28 nm MOSFET器件的3维结构,创建了单粒子的迁移率和载流子等仿真物理模型,仿真模拟了重离子入射位置、LET值、入射角度及器件的漏极掺杂浓度、漏极偏置电压对28 nm MOSFET器件单粒子效应的影响,分析了重离... 详细信息

利用SILVACO TCAD软件构建了28 nm MOSFET器件的3维结构,创建了单粒子的迁移率和载流子等仿真物理模型,仿真模拟了重离子入射位置、LET值、入射角度及器件的漏极掺杂浓度、漏极偏置电压对28 nm MOSFET器件单粒子效应的影响,分析了重离子入射引起器件双极放大效应。仿真结果表明:MOSFET器件对单粒子效应敏感的位置是临近轻掺杂的漏极,通过提取耗尽区电势,发现不同位置单粒子漏极瞬态电流的峰值与电势的大小基本保持一致;漏极瞬态电流峰值随着LET值和漏极偏置电压的增大而增大,而随着器件的漏极掺杂浓度的增大而减小;漏极瞬态电流峰值随着粒子入射角度的增大而增大,这是器件内部电离面积的变化引起的。另外,单粒子效应会导致MOSFET体内的寄生晶体管导通,使大量电子从源极流入漏极,产生的电流与单粒子电离形成的电流叠加使电路节点电压突变,导致电路功能紊乱,研究表明双极放大增益可达3.3。

关键词： MOSFET 单粒子效应 TCAD仿真瞬态电流双极放大增益

Connectome-based predictive modelling can predict follow-up craving after abstinence in individuals with opioid use disorders

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General Psychiatry 2023年第6期36卷 472-480页

作者： Wenhan Yang Jungong Han Jing Luo Fei Tang Li Fan Yanyao Du longtao Yang Jun zhang Huiting zhang Jun Liu The Second Xiangya Hospital of Central South University ChangshaHunanChina Department of Computer Science Aberystwyth UniversityAberystwythUK Department of Radiology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina Hunan Judicial Police Academy ChangshaHunanChina siemens Healthineers Ltd WuhanHubeiChina Clinical Research Center for Medical Imaging in Hunan Province ChangshaHunanChina Department of Radiology Quality Control Center in Hunan Province ChangshaHunanChina

Background Individual differences have been detected in individuals with opioid use disorders(OUD)in rehabilitation following protracted *** studies suggested that prediction models were effective for individual-level prognosis based on neuroimage data in substance use disorders(SUD).Aims This prospective cohort study aimed to assess neuroimaging biomarkers for individual response to protracted abstinence in opioid users using connectome-based predictive modelling(CPM).Methods One hundred and eight inpatients with OUD underwent structural and functional magnetic resonance imaging(fMRI)scans at *** Heroin Craving Questionnaire(HCQ)was used to assess craving levels at baseline and at the 8-month follow-up of *** with leave-one-out cross-validation was used to identify baseline networks that could predict follow-up HCQ scores and changes in HCQ(HCQtolow V-up-HCQpa baseline).Then,the follow-up aseline predictive ability of identified networks was tested in a separate,heterogeneous sample of methamphetamine individuals who underwent MRI scanning before abstinence for *** CPM could predict craving changes induced by long-term abstinence,as shown by a significant correlation between predicted and actual HCQ fllow-up(r=0.417,p<0.001)and changes in HCQ(negative:r=0.334,p=0.002;positive:r=0.233,p=0.038).Identified craving-related prediction networks included the somato-motor network(SMN),salience network(SALN),default mode network(DMN),medial frontal network,visual network and auditory *** addition,decreased connectivity of frontal-parietal network(FPN)-SMN,FPN-DMN and FPN-SALN and increased connectivity of subcortical network(SCN)-DMN,SCN-SALNandSCN-SMN were positively correlated with craving *** These findings highlight the potential applications of CPM to predict the craving level of individuals after protracted abstinence,as well as the generalisation ability;the identified brain networks might be the focus o

关键词： opioid disorders network

Inducing Fe 3d Electron Delocalization and Spin‑State Transition of FeN_(4) Species Boosts Oxygen Reduction Reaction for Wearable Zinc–Air Battery

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Nano-Micro Letters 2023年第4期15卷 23-39页

作者： Shengmei Chen Xiongyi Liang Sixia Hu Xinliang Li Guobin zhang Shuyun Wang longtao Ma Chi‑Man Lawrence Wu Chunyi Zhi Juan Antonio Zapien Department of Materials Science and Engineering City University of Hong KongHong Kong 999077People’s Republic of China Sustech Core Research Facilities Southern University of Science and Technology1088 Xueyuan BlvdShenzhenGuangdong 518055People’s Republic of China Frontiers Science Center for Flexible Electronics Institute of Flexible ElectronicsNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhenGuangdong518055People’s Republic of China

Transition metal-nitrogen-carbon materials(M-N-Cs),particularly Fe-N-Cs,have been found to be electroactive for accelerating oxygen reduction reaction(ORR)*** substantial efforts have been devoted to design Fe-N-Cs with increased active species content,surface area,and electronic conductivity,their performance is still far from ***,there is limited research about regulation on the electronic spin states of Fe centers for Fe-N-Cs electrocatalysts to improve their catalytic ***,we introduce Ti_(3)C_(2) MXene with sulfur terminals to regulate the electronic configuration of FeN_(4) species and dramatically enhance catalytic activity toward *** MXene with sulfur terminals induce the spin-state transition of FeN_(4) species and Fe 3d electron delocalization with d band center upshift,enabling the Fe(II)ions to bind oxygen in the end-on adsorption mode favorable to initiate the reduction of oxygen and boosting oxygen-containing groups adsorption on FeN_(4) species and ORR *** resulting FeN_(4)-Ti_(3)C_(2)Sx exhibits comparable catalytic performance to those of commercial *** developed wearable ZABs using FeN_(4)-Ti_(3)C_(2)Sx also exhibit fast kinetics and excellent *** study confirms that regulation of the electronic structure of active species via coupling with their support can be a major contributor to enhance their catalytic activity.

关键词： Fe 3d electron delocalization Spin-state transition Oxygen reduction reaction Wearable zinc-air batteries

3D printed silk-gelatin hydrogel scaffold with different porous structure and cell seeding strategy for cartilage regeneration

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Bioactive Materials 2021年第10期6卷 3396-3410页

作者： Qingtao Li Sheng Xu Qi Feng Qiyuan Dai longtao Yao Yichen zhang Huichang Gao Hua Dong Dafu Chen Xiaodong Cao National Engineering Research Center for Tissue Restoration and Reconstruction(NERC-TRR) South China University of TechnologyGuangzhouGuangDong510641China Department of Biomedical Engineering School of Material Science and EngineeringSouth China University of TechnologyGuangzhouGuangDong510641China School of Medicine South China University of TechnologyGuangzhouGuangDong510641China Key Laboratory of Biomedical Engineering of Guangdong Province Key Laboratory of Biomedical Materials and Engineering of the Ministry of EducationInnovation Center for Tissue Restoration and ReconstructionSouth China University of TechnologyGuangzhouGuangDong510641China Laboratory of Bone Tissue Engineering Beijing Laboratory of Biomedical MaterialsBeijing Research Institute of Orthopaedics and TraumatologyBeijing JiShuiTan HospitalBeijing100035China Zhongshan Institute of Modern Industrial Technology of SCUT ZhongshanGuangdong528437China

Hydrogel scaffolds are attractive for tissue defect repair and reorganization because of their human tissue-like ***,most hydrogels offer limited cell growth and tissue formation ability due to their submicron-or nano-sized gel networks,which restrict the supply of oxygen,nutrients and inhibit the proliferation and differentiation of encapsulated *** recent years,3D printed hydrogels have shown great potential to overcome this problem by introducing macro-pores within *** this study,we fabricated a macroporous hydrogel scaffold through horseradish peroxidase(HRP)-mediated crosslinking of silk fibroin(SF)and tyramine-substituted gelatin(GT)by extrusion-based low-temperature 3D *** physicochemical characterization,we found that this hydrogel has excellent structural stability,suitable mechanical properties,and an adjustable degradation rate,thus satisfying the requirements for cartilage *** suspension and aggregate seeding methods were developed to assess the inoculation efficiency of the ***,the chondrogenic differentiation of stem cells was *** cells in the hydrogel differentiated into hyaline cartilage when the cell aggregate seeding method was used and into fibrocartilage when the cell suspension was ***,the effect of the hydrogel and stem cells were investigated in a rabbit cartilage defect *** implantation for 12 and 16 weeks,histological evaluation of the sections was *** found that the enzymatic cross-linked and methanol treatment SF5GT15 hydrogel combined with cell aggregates promoted articular cartilage *** summary,this 3D printed macroporous SF-GT hydrogel combined with stem cell aggregates possesses excellent potential for application in cartilage tissue repair and regeneration.

关键词： Silk hydrogel 3D printing Enzymatic cross-linking Cell aggregate seeding Cartilage regeneration