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Deeply learned broadband encoding stochastic hyperspectral imaging

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Light(Science & Applications) 2021年第6期10卷 969-975页

作者： Wenyi Zhang Hongya Song Xin He longqian huang Xiyue Zhang Junyan Zheng Weidong Shen Xiang Hao Xu Liu State Key Laboratory of Modern Optical Instrumentation College of Optical Science and TechnologyZhejiang UniversityHangzhou 310027China Intelligent Optics Photonics Research Center Jiaxing Institute of Zhejiang UniversityJiaxing 314000 Zhejiang ProvineeChina

Many applications requiring both spectral and spatial information at high resolution benefit from spectral *** different technical methods have been developed and commercially available,computational spectral cameras represent a compact,lightweight,and inexpensive ***,the tradeoff between spatial and spectral resolutions,dominated by the limited data volume and environmental noise,limits the potential of these *** this study,we developed a deeply learned broadband encoding stochastic hyperspectral *** particular,using advanced artificial intelligenee in filter design and spectrum reconstruction,we achieved 7000-11,000 times faster signal processing and〜10 times improvement regarding noise *** improvements enabled us to precisely and dynamically reconstruct the spectra of the entire field of view,previously unreachable with compact computational spectral cameras.

关键词： solution. stochastic spectral

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吗啉硝唑临床应用的研究进展

中国抗生素杂志 2024年第2期49卷 151-156页

作者：田丹丽黄龙千梁春坡天津市第一中心医院天津300192 天津医科大学天津300070 天津医科大学总医院天津300052

从结构特点、抗菌机制、抗菌活性、药动学、药物相互作用及临床应用等方面全面介绍吗啉硝唑的研究进展,为深入研究提供参考。吗啉硝唑作为新型硝基咪唑类抗菌药,抗菌活性强,不易产生耐药性,临床应用日益增多。多项研究证实吗啉硝唑疗效... 详细信息

从结构特点、抗菌机制、抗菌活性、药动学、药物相互作用及临床应用等方面全面介绍吗啉硝唑的研究进展,为深入研究提供参考。吗啉硝唑作为新型硝基咪唑类抗菌药,抗菌活性强,不易产生耐药性,临床应用日益增多。多项研究证实吗啉硝唑疗效显著,安全性高。吗啉硝唑具有科研和临床应用价值,值得深入研究。

关键词：吗啉硝唑临床应用不良反应抗菌作用机制抗菌活性

生物炭及其复合材料吸附重金属离子的研究进展

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材料导报 2017年第19期31卷 135-143页

作者：王耀梅向阳段正洋何昌华徐晓军解道雷徐龙乾黄启华昆明理工大学环境科学与工程学院昆明650500 云南省环境工程评估中心昆明650100

生物炭作为废弃生物质在缺氧条件下热解得到的固态产物,由于其表面具有丰富的官能团及较强的吸附性能等优点而被广泛应用到重金属废水处理。近年来,众多学者将生物炭与其他材料通过物理、化学方法结合,制备出对重金属离子具有优良吸附... 详细信息

生物炭作为废弃生物质在缺氧条件下热解得到的固态产物,由于其表面具有丰富的官能团及较强的吸附性能等优点而被广泛应用到重金属废水处理。近年来,众多学者将生物炭与其他材料通过物理、化学方法结合,制备出对重金属离子具有优良吸附性能的生物炭复合材料。首先介绍了生物炭及其复合材料的制备方法和基本特性,其次考察了生物炭及其复合材料对重金属离子的吸附效果及影响因素,最后阐述了生物炭及其复合材料吸附重金属离子的机制,并对生物炭及其复合材料处理重金属离子的发展方向进行了展望。

关键词：生物炭复合材料重金属影响因素吸附机制

A general stabilizing strategy based on vitamin C for n-type organic semiconductors

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Science China Materials 2025年第01期 303-304页

作者： Hui huang College of Materials Science and Opto-Electronic Technology Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Organic semiconductors (OSCs), as an emerging next-generation semiconductor material, hold promising prospects in fields such as flexible displays, electronic skins, smart healthcare,and the Internet of Things, due to their excellent flexibility,solution processability, and tunable band structures [1,2]. These molecules are often classified into n-type and p-type, depending on whether the prevalent charge carriers are electrons or holes[3].

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Efficient white-light-emitting lead-free halide double perovskites enabling full-spectrum pc-WLEDs

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Science China Materials 2025年第1期 305-306页

作者： Xiaoyong huang College of Physics and Optoelectronics Taiyuan University of Technology

With the rapid development of solid-state lighting, an important goal of phosphor-converted white light-emitting diodes (pc-WLEDs) is to provide a healthy and comfortable fullspectrum artificial light source with a co...

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Quickly obtaining densely dispersed coherent particles in steel matrix and its related mechanical property

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 111-118页

作者： Xiaoxiao Wang Qingsong huang School of Chemical Engineering Sichuan UniversityChengdu 610065China

Densely distributed coherent nanoparticles(DCN)in steel matrix can enhance the work-hardening ability and ductility of steel *** the routes to this end can be generally classified into the liquid-solid route and the solid-solid ***,the formation of DCN structures in steel requires long processes and complex *** far,obtaining steel with coherent particle enhancement in a short time remains a bottleneck,and some necessary steps remain ***,we show a high-efficiency liquid-phase refining process reinforced by a dynamic magnetic ***-Y-Mn-O particles had an average size of around(3.53±1.21)nm and can be obtained in just around 180 *** small nanoparticles were coherent with the matrix,implying no accumulated dislocations between the particles and the steel *** findings have a potential application for improving material machining capacity,creep resistance,and radiation resistance.

关键词： ferritic steels coherent particles microstructure compression test work hardening

Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

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Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen huang Stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

The role of axon guidance molecules in the pathogenesis of epilepsy

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Neural Regeneration Research 2025年第5期20卷 1244-1257页

作者： Zheng Liu Chunhua Pan Hao huang Department of Neurology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence suggests that axon guidance molecules play a role in the structural and functional modifications of neural networks and that the dysregulation of these molecules is associated with epilepsy susceptibility. In this review, we discuss the essential role of axon guidance molecules in neuronal activity in patients with epilepsy as well as the impact of these molecules on synaptic plasticity and brain tissue remodeling. Furthermore, we examine the relationship between axon guidance molecules and neuroinflammation, as well as the structural changes in specific brain regions that contribute to the development of epilepsy. Ample evidence indicates that axon guidance molecules, including semaphorins and ephrins, play a fundamental role in guiding axon growth and the establishment of synaptic connections. Deviations in their expression or function can disrupt neuronal connections, ultimately leading to epileptic seizures. The remodeling of neural networks is a significant characteristic of epilepsy, with axon guidance molecules playing a role in the dynamic reorganization of neural circuits. This, in turn, affects synapse formation and elimination. Dysregulation of these molecules can upset the delicate balance between excitation and inhibition within a neural network, thereby increasing the risk of overexcitation and the development of epilepsy. Inflammatory signals can regulate the expression and function of axon guidance molecules, thus influencing axonal growth, axon orientation, and synaptic plasticity. The dysregulation of neuroinflammation can intensify neuronal dysfunction and contribute to the occurrence of epilepsy. This review delves into the mechanisms associated with

关键词： axon guidance drug-resistant epilepsy epilepsy nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity neurons synaptic remodeling

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

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Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin Su Taiqi huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress