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Electrolytic silicon/graphite composite from SiO_(2)/graphite porous electrode in molten salts as a negative electrode material for lithium-ion batteries

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Rare Metals 2022年第2期41卷 438-447页

作者： Ning Wang Yu-yang Liu Zhi-Xia Shi Zhang-long Yu Hua-Ying Duan Sheng Fang Juan-Yu yang xing-Ming Wang GRIREM Advanced Materials Co. Ltd.China Automotive Battery Research Institute Co.Ltd.General Research Institute for Nonferrous MetalsBeijing 100088China GRINM Resources and Environment Tech.Co.Ltd. General Research Institute for Nonferrous MetalsBeijing 100088China China Automotive Battery Research Institute Co.Ltd. General Research Institute for Nonferrous MetalsBeijing 100088China

Nano-silicon(nano-Si)and its composites have been regarded as the most promising negative electrode materials for producing the next-generation Li-ion batteries(LIBs),due to their ultrahigh theoretical ***,the commercial applications of nano Si-based negative electrode materials are constrained by the low cycling stability and high *** molten salt electrolysis of SiO_(2)is proven to be suitable to produce nano-Si with the advantages of in-situ microstructure control possibilities,cheap affordability and scale-up process ***,an economical approach for electrolysis,with a SiO_(2)/graphite porous electrode as cathode,is adopted to produce nano-Si/graphite composite negative electrode materials(SGNM)in this *** electrolytic product of the optimized porous electrode is taken as the negative electrode materials for LIBs,and it offers a capacity of 733.2 mAh·g^(-1)and an initial coulombic efficiency of 86.8%in a coin-type ***,the capacity of the SGNM retained 74.1%of the initial discharging capacity after 50 cycles at 0.2C,which is significantly higher than that of the simple mixture of silicon and graphite obtained from the formation of silicon carbide(SiC)between nano-Si and graphite ***,this new approach can be applied to a large-scale production.

关键词： Li-ion battery Negative electrode materials Molten salt electrolysis Nano-silicon

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Motional Quantum-State Engineering and Implementation of a Quantum Phase-Gate for Multiple Trapped Ions

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Communications in Theoretical Physics 2006年第2X期46卷 297-302页

作者： yang Wen-xing State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Center for Cold Atom Physics Wuhan Institute of Physics and Mathematics the Chinese Academy of Sciences Wuhan 430071 China Guaduate School of the Chinese Academy of Sciences Beijing 100049 China

We propose a scheme to generate a superposition of motional coherent states with arbitrary coefficients on a line in phase space and implement a quantum controlled phase-gate for multiple trapped ions with a single standing-wave laser pulse whose carrier frequency is tuned to the ions transition. In the scheme each ion does not need to be exactly positioned at the node of the standing wave, which is very important from viewpoint of experiment, Furthermore, our scheme may allow the generation of a superposition of coherent states with large mean phonon number for a large number of trapped ions in a fast way by choosing suitable laser intensity. We show that it can also be used to generate maximally entangled states of multiple trapped ions.

关键词： quantum-state engineering quantum computation trapped ions

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Preparation of Entanglement and Schrdinger Cat States of Superconducting Quantum Interference Devices Qubits via Coupling to a Microwave Cavity

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Communications in Theoretical Physics 2008年第3期49卷 643-648页

作者： yang Wen-xing Department of Physics Southeast University Nanjing 210096 China Wuhan Institute of Physics and Mathematics the Chinese Academy of Sciences Wuhan 430071 China

An alternative scheme is proposed for the generation of n-qubit W states of superconducting quantum interference devices （SQUID） in cavity QED. In this scheme, Raman coupling of two lower flux states of SQUID system is achieved via a microwave pulse and the cavity mode. Conditioned on no photon leakage from the cavity, the n-qubit W state can be generated whether the effective coupling parameters of the SQUID to cavity mode and classical microwave fields are the same or different. Our strictly numerical simulations of the time evolution of the system including decay show that the success probability of our scheme is almost unity and the interaction time is on the order of 10-9 s. The scheme can also be used to generate the Schrodinger cat states of multi-SQUID.

关键词： entanglement superconducting cavity

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中国老年人午睡时长和夜间睡眠与抑郁症状的关联:基于2020年CHARLS数据的实证分析

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中国全科医学 2025年第5期28卷 560-567页

作者：周梅杨爱琼邢英王玉玲新疆医科大学第一附属医院干部保健中心新疆维吾尔自治区乌鲁木齐市830054

背景随着我国进入中度老龄化社会,老年人心理健康问题逐年增加,而生活习惯与老年人的心理健康密切相关。目的探讨我国老年人午睡时长、夜间睡眠与抑郁症状的关系,基于生活习惯角度推荐睡眠时间,为老年人抑郁早期防控提供科学依据。方法... 详细信息

背景随着我国进入中度老龄化社会,老年人心理健康问题逐年增加,而生活习惯与老年人的心理健康密切相关。目的探讨我国老年人午睡时长、夜间睡眠与抑郁症状的关系,基于生活习惯角度推荐睡眠时间,为老年人抑郁早期防控提供科学依据。方法基于2023-11-16公开发布第五轮(2020年)中国健康与养老追踪调查项目(CHARLS),纳入符合研究标准的8233名为研究对象。采用抑郁评定量表(CSE-D10)评估老年人抑郁症状,午睡时长划分5级:不午睡、<30 min、30~59 min、60~89 min、≥90 min,夜间睡眠分为5级:≥8 h、7~<8 h、6~<7 h、5~<6 h、<5 h。采用多因素Logistic回归分析探究影响老年人发生抑郁症状的因素,随机森林模型分析午睡时长、夜间睡眠在老年人发生抑郁症状中的重要程度,限制性立方样条曲线进一步探索午睡时长、夜间睡眠时长与抑郁症状发生风险之间的剂量-反应关系。结果2020年调查期间,中国老年人抑郁症状的发生率为24.84%(2045/8233)。多因素Logistic回归分析结果显示,午睡时长30~59 min是老年人发生抑郁症状的保护因素(OR=0.814,95%CI=0.673~0.985,P=0.034),夜间睡眠时间<5 h是老年人发生抑郁症状的危险因素(OR=1.705,95%CI=1.435~2.027,P<0.001)。女性、未婚/分居/离异/丧偶、失能、身体疼痛、强度体力活动、自评健康状况下降、生活满意度下降、卒中、帕金森病会增加老年人发生抑郁症状的风险(P<0.05)。随机森林模型显示,午睡时长、夜间睡眠时间对抑郁症状影响的重要性较高。午睡时长与发生抑郁症状之间存在非线性关系(P_(nonlinear)<0.05),老年人发生抑郁症的风险在午睡时长30 min后随着时间的增加而持续降低,最低水平约为50 min,午睡时长超过75 min后抑郁症状的发生风险会增加。老年人患抑郁症状的发生风险在夜间睡眠6 h后随着时间的增加而持续降低,最低水平约为7 h,睡眠时间超过9 h后抑郁的风险会增加(Poverall<0.05)。结论中国老年人群抑郁症的患病率较高(24.84%),午睡时长、夜间睡眠的持续时间与抑郁症之间呈J型关系,建议老年人每天午睡30~75 min,适度的午睡时长有效降低老年人发生抑郁症状的风险,同时夜间睡眠6~9 h降低抑郁症状的发生风险,对老年人群抑郁症的早期防控具有一定的意义。

关键词：抑郁老年人午睡时长夜间睡眠中国健康与养老追踪调查项目

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Advances in Vision-Based Lane Detection：Algorithms,Integration,Assessment,and Perspectives on ACP-Based Parallel Vision

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IEEE/CAA Journal of Automatica Sinica 2018年第3期5卷 645-661页

作者： yang xing Chen Lv long Chen Huaji Wang Hong Wang Dongpu Cao Efstathios Velenis Fei-Yue Wang Advanced Vehicle Engineering Centre Cranfield University Bedford MK43 0AL U.K Vehicle Intelligence Pioneers Ltd Qingdao 266000 China School of Data and Computer Science Sun Yat-Sen University Guangzhou 510275 China Mechanical and Mechatronics Engineering with the University of Waterloo 200 University Avenue West Waterloo ON N2L 3G1 Canada State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing 100190 China ieee

Lane detection is a fundamental aspect of most current advanced driver assistance systems(ADASs). A large number of existing results focus on the study of vision-based lane detection methods due to the extensive knowledge background and the low-cost of camera devices. In this paper, previous visionbased lane detection studies are reviewed in terms of three aspects, which are lane detection algorithms, integration, and evaluation methods. Next, considering the inevitable limitations that exist in the camera-based lane detection system, the system integration methodologies for constructing more robust detection systems are reviewed and analyzed. The integration methods are further divided into three levels, namely, algorithm, system,and sensor. Algorithm level combines different lane detection algorithms while system level integrates other object detection systems to comprehensively detect lane positions. Sensor level uses multi-modal sensors to build a robust lane recognition system. In view of the complexity of evaluating the detection system, and the lack of common evaluation procedure and uniform metrics in past studies, the existing evaluation methods and metrics are analyzed and classified to propose a better evaluation of the lane detection system. Next, a comparison of representative studies is performed. Finally, a discussion on the limitations of current lane detection systems and the future developing trends toward an Artificial Society, Computational experiment-based parallel lane detection framework is proposed.

关键词： Advanced driver assistance systems(ADASs) ACP theory benchmark lane detection parallel vision performance evaluation

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Magnetic separation of metal sulfides/oxides by Fe3O4 at room temperature and atmospheric pressure

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Rare Metals 2019年第5期38卷 379-389页

作者： Jia-Hui Ji Yi-Fei Xiao Bin Shen Qiu-Ying Yi Jin-long Zhang Ming-yang xing Key Laboratory for Advanced Materials and Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology

The recovery of heterogeneous catalysts can save costs and avoid secondary pollution,but its separation efficiency and recovery cost are limited by conventional separation methods such as precipitation–flocculation,centrifugation and *** this paper,we found that surface-defective metal sulfides/oxides(WS2,CuS,ZnS,MoS2,CdS,TiO2,MoO2 and ZnO)commonly used in advanced oxidation processes(AOPs)could be magnetically recovered at room temperature and atmospheric pressure by mechanically mixing with *** potential,Raman,X-ray photoelectron spectroscopy(XPS)and electro-spin resonance(ESR)spectra were measured to explore the mechanism of the magnetic separation *** exposed active metal sites on the surface of defective metal sulfides/oxides are beneficial for the formation of chemical bonds,which are combined with electrostatic force to be responsible for the magnetic ***,other factors affecting the magnetic separation were also investigated,such as the addition of amount of Fe3O4,different solvents and particle ***,WS2 was chosen to be applied as a co-catalyst in Fenton reaction,which could be well separated by the magnetic Fe3O4 to achieve the recycle of catalyst in Fenton *** research provides a general strategy for the recycle of metal sulfides/oxides in the catalytic applications.

关键词： Magnetic separation Metal sulfides/oxides Recycle Fenton reaction

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Epigenetic regulation of the inflammatory response in stroke

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Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi Liang Fei yang Zixiao Li Qian Li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment

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piR-7472影响电压调控钾离子通道促进小鼠成骨细胞分化的机制

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中国组织工程研究 2025年第14期29卷 2868-2874页

作者：隆宇斌王湘斌樊基耿杨厚志杨洋李勇邵阳市中心医院脊柱外科湖南省邵阳市422000 天津医科大学研究生院天津市300070 邵阳市中心医院肿瘤内科湖南省邵阳市422000

背景:现有研究在PIWI相互作用RNA(piRNA)抗骨质疏松方面取得了重大进展,但piRNA发挥功能的具体靶点和相关机制仍有待探索。目的:探讨piR-7472对小鼠成骨细胞(MC3T3-E1细胞)分化的影响及下游机制。方法:①12只C57/BL6J小鼠随机分为假手... 详细信息

背景:现有研究在PIWI相互作用RNA(piRNA)抗骨质疏松方面取得了重大进展,但piRNA发挥功能的具体靶点和相关机制仍有待探索。目的:探讨piR-7472对小鼠成骨细胞(MC3T3-E1细胞)分化的影响及下游机制。方法:①12只C57/BL6J小鼠随机分为假手术组和卵巢切除组,每组6只,术后8周通过Micro-CT检测小鼠的骨量,RT-qPCR检测piR-7472的表达;②将MC3T3-E1细胞分为NC mimics组、piR-7472 mimics组、NC inhibitor组与piR-7472 inhibitor组,转染后成骨诱导7 d采用RT-qPCR检测piR-7472、骨桥蛋白、胶原蛋白Ⅰ、Runt相关转录因子2、钾电压门控通道调节因子亚家族F成员1 mRNA的表达;成骨诱导7 d采用Western blot检测骨桥蛋白、Runt相关转录因子2、骨形态发生蛋白2、钾电压门控通道调节因子亚家族F成员1(KCNF1)蛋白表达;成骨诱导14 d通过碱性磷酸酶染色检测碱性磷酸酶的表达;成骨诱导21 d通过茜素红染色检测矿化结节数量;③双荧光素酶报告基因实验观察piR-7472是否能与钾电压门控通道调节因子亚家族F成员1相结合。结果与结论:①与假手术组相比,卵巢切除组小鼠骨密度、骨体积分数、骨小梁厚度、骨小梁数量明显下降,骨小梁分离度明显升高,并且骨组织中piR-7472 mRNA表达明显下调;②与NC组相比,piR-7472 mimics组骨桥蛋白、胶原蛋白Ⅰ、Runt相关转录因子2的mRNA表达明显升高,骨桥蛋白、Runt相关转录因子2、骨形态发生蛋白2的蛋白表达明显升高,矿化沉积与碱性磷酸酶表达增多;与NC inhibitor组相比,piR-7472 inhibitor组骨桥蛋白、胶原蛋白Ⅰ、Runt相关转录因子2的mRNA表达明显降低,骨桥蛋白、Runt相关转录因子2、骨形态发生蛋白2的蛋白表达明显降低,矿化沉积与碱性磷酸酶表达降低;③通过miRanda数据库预测发现piR-7472能与KCNF1相互作用;双荧光素酶报告基因实验发现piR-7472 mimcis能与钾电压门控通道调节因子亚家族F成员1结合并促进其表达。结果表明:piR-7472能够促进成骨前体细胞MC3T3-E1成骨分化,其发挥作用的机制可能是通过促进KCNF1表达实现的。

关键词：成骨细胞MC3T3-E1 PIWI相互作用RNA 成骨分化骨质疏松症电压调控的钾离子通道 KCNF1

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Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin yang Yu-Wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

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Tuning the oxidation state of Ru to surpass Pt in hydrogen evolution reaction

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Nano Research 2021年第11期14卷 4321-4327页

作者： Rongpeng Ma Ying Wang Guoqiang Li long yang Shiwei Liu Zhao Jin Xiao Zhao Junjie Ge Wei xing State Key Laboratory of Electroanalytical Chemistry Laboratory of Advanced Power SourcesChangchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China State Key Laboratory of Automotive Simulation and Control School of Materials Science and Engineering Key Laboratory of Automobile Materials of MOEJilin UniversityChangchun130012China

The high price of state-of-the-art Pt electrocatalysts has plagued the acidic water electrolysis technique for decades. As a cheaper alternative to Pt, ruthenium is considered an inferior hydrogen evolution reaction (HER) catalyst than Pt due to its high susceptibility to oxidation and loss of activity. Herein, we reveal that the HER activity on Ru based catalysts could surpass Pt via tuning Ru oxidation state. Specifically, RuP clusters encapsulated in few layers of N, P-doped carbon (RuP@NPC) display a minimum over potential of 15.6 mV to deliver 10 mA·cm^(−2). Moreover, we for the first time show that a Ru based catalyst could afford current density up to 4 A·cm^(−2) in a practical water electrolysis cell, with voltage even lower than the Pt/C-based cell, as well as high robustness during 200 h operation. Using a combination of experiment probing and calculation, we postulate that the suitably charged Ru (∼ +2.4) catalytic center is the origin for its superior catalytic behavior. While the moderately charged Ru is empowered with optimized H adsorption behavior, the carbon encapsulation layers protect RuP clusters from over oxidation, thereby conferring the catalyst with high robustness.

关键词： RuP clusters Ru oxidation state hydrogen evolution encapsulating/confining layers

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