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文化生态学视野下的岭南园林

西北林学院学报 2014年第2期29卷 288-292页

作者：汪耀龙许先升海南大学园艺园林学院海南海口570228

岭南园林作为我国园林艺术的一个重要分支,具有极大的研究价值。以"文化生态学"的研究方法,从自然环境、种群文化背景、与外来文化碰撞等方面,对于岭南园林的产生、沿革、演变进行较为全面的分析,进而探讨岭南园林的流变脉络。

关键词：文化生态学岭南园林环境演变

Effects of OGG1 methylation regulated byH19/SAHH/DNMT1 on the oxidative DNA damage and cell cycle arrest related to PAHs exposure

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Effects of OGG1 methylation regulated byH19/SAHH/DNMT1 on th...

Are tuberculosis patients adherent to prescribed treatments in China? Results of a prospective cohort study

中国毒理学会第九次全国毒理学大会

作者： LI Xue-jing FU Ye PAN Bao-long NIUYing-ying ZHANG Bin ZHAO Xinyu NIEJi-sheng WANG Rui-sheng YANG Jin Department of Occupational Health School of Public Health Shanxi Medical University General Hospital of Taiyuan Iron ＆ Steel （Group） Co. Ltd.

OBJECTIVE To investigate the effects of OGG1 methylation regulated by H19/SAHH/DNMT1 on the oxidative DNA damage and cell cycle arrest related to PAHs exposure. METHODS We used high performance liquid chromatography mass spectrometry（HPLC-MS） equipped to detect urine biomarkers of PAHs exposure, including 2-hydroxynaphthalene（2-NAP）, 2-hydroxyfluorene（2-FLU）, 9-hydroxyphenanthrene（9-PHE）, 1-hydroxypyrene（1-OHP）. The levels of SAM and SAH in plasma were detected by HPLC-ultraviolet, and the expression level of H19 was detected by RT-PCR. The protein expression levels of SAHH and DNMT1 were detected by Western blot. The content of 8-OHdG and DNMT1 activity were detected by *** interaction between H19 and SAHH was detected by RNA Binding ProteinImmunoprecipitation Assay. The interaction between SAHH and DNMT1 was detected by co-immunoprecipitation. The localization between H19, SAHH and DNMT1 was observed by lnc RNA fluorescence in situ hybridization（FISH） combined with laser scanning confocal *** methylation level of OGG1 gene was detected by pyrosequencing, and the cell cycle was detected by flow cytometry. RESULTS After adjusting for covariates, urinary 1-hydroxypyrene（1-OHP） levels were positively associated with blood H19 RNA expression（OR: 1.51, 95% CI: 1.03-2.19）, while were negatively associated with plasma SAHH activity（OR: 0.63, 95% CI: 0.41-0.98）. H19 binding to SAHH exaggerate DNA methyltransferase 1（DNMT1） expressions and activity with BaP *** of H19 enhanced the interaction of SAHH and DNMT1 induced by BaP. Although BaPtreated cells H19 single knockdown expectedly decreased OGG1 methylation, reduced oxidative DNA damage and recovered S phase arrest with altering SAHH and DNMT1, while SAHH or DNMT1 single knockdown shows the opposite trend. And the H19/SAHH double knockdown restored OGG1 methylation, oxidative DNA damage and S phase to the control level while SAHH/DNMT1 double knockdown aggravated the alteration. CONCLUSI

关键词： Polycyclic aromatic hydrocarbons Oxidative DNA damage 8-oxoguanine DNA glycosylase 1 long non-coding RNA H19 S-adenosylhomocysteine hydrolase DNA methyltransferase

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Infectious Diseases of Poverty 2016年第1期5卷 319-327页

作者： Xun Lei Ke Huang Qin Liu Yong-Feng Jie sheng-Lan Tang China Effective Health Care Network Research Center for Medicine and Social DevelopmentInnovation Center for Social Risk Governance in HealthSchool of Public Health and ManagementChongqing Medical UniversityChongqingChina Public Health Clinical Center of Chengdu ChengduChina Changhang Hospital of Chongqing ChongqingChina Duke University DurhamNCUSA

Background:Tuberculosis(TB)patients face numerous difficulties adhering to the long-term,rigorous TB treatment *** on TB patients’treatment adherence vary across existing literature and official *** present study attempted to determine the actual treatment adherence of new TB patients and to identify factors leading to ***:A prospective cohort of 481 newly confirmed TB patients from three counties in western China were enrolled during June to December 2012 and was followed until June *** who missed at least one dose of drugs or one follow-up re-examination during the treatment course were deemed as *** factors were identified using a logistic regression ***:A total of 173(36.0%)patients experienced non-adherence and the loss to follow-up cases reached 136(28.2%).Only 13.9%of patients took drugs under direct observation,and 60.5%of patients were supervised by phone *** analyses suggested that patients who were observed by family members(OR:5.54,95%CI:2.87–10.69)and paying monthly service expenses above 450 RMB(OR:2.08,95%CI:1.35–3.19)were more likely to be non-adherent,while supervision by home visit(OR:0.06,95%CI:0.01–0.28)and phone calls(OR:0.27,95%CI:0.17–0.44)were protective ***:Despite recent efforts,a large proportion of newly confirmed TB patients could not adhere to standard TB treatment,and patients’lost to follow-up was still a serious *** treatment supervision and heavy financial burden might be the main causes for *** needs to be done to enhance treatment supervision policies and financial supports to both health providers and TB patients.

关键词： Tuberculosis Adherence Prospective cohort study China

双耦合电感零输入纹波高增益QBC-VMU集成变换器

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中国电机工程学报 2016年第23期36卷 6501-6510,6617页

作者：杨杰于东升朱虹王龙侯圣中国矿业大学信息与电气工程学院江苏省徐州市221116

低输入电流纹波高增益DC-DC变换器是光伏、燃料电池等低电压输入分布式发电系统的重要组成部分,对推广应用可再生能源发电起着重要作用。该文基于二次型升压变换器和倍压单元,提出一种双耦合电感零输入电流纹波高增益QBC-VMU集成变换器... 详细信息

低输入电流纹波高增益DC-DC变换器是光伏、燃料电池等低电压输入分布式发电系统的重要组成部分,对推广应用可再生能源发电起着重要作用。该文基于二次型升压变换器和倍压单元,提出一种双耦合电感零输入电流纹波高增益QBC-VMU集成变换器。通过二次型升压变换器输入电感和储能电感的耦合,合理地配置匝比和耦合系数,可近似实现输入电流的零纹波。倍压电路中的储能电感由一对耦合电感代替,可获取高升压增益,且避免出现极限占空比。由箝位二极管和储能电容组成的吸收电路,可降低由漏感造成的开关管两端的电压尖峰;倍压电路中的续流二极管和储能电容组成的漏感能量回收电路,可降低能量损耗,提高变换器效率。该文在分析变换器工作原理及切换模式的基础上,搭建一台输入/输出电压为18V/200V的实验样机,样机测试结果验证了理论分析的正确性。

关键词：二次型升压变换器电流纹波耦合电感高增益吸收电路能量回收电路

Atypical pituitary hormone–target tissue axis

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Frontiers of Medicine 2023年第1期17卷 1-17页

作者： Chao Xu Zhao He Yongfeng song Shanshan Shao Guang Yang Jiajun Zhao Department of Endocrinology and Metabolism Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China Department of Endocrinology and Metabolism Shandong Provincial HospitalCheeloo College of MedicineShandong UniversityJinan 250021China Beijing Institute of Tropical Medicine Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glands to actuate their manifold ***,a number of studies have shown that multiple types of pituitary hormone receptors are widely expressed in non-classical target *** pituitary gland-derived hormone exhibits a wide range of nonconventional biological effects in these non-classical target ***,the extra biological functions of pituitary hormones,thyroid-stimulating hormone,follicle-stimulating hormone,luteinizing hormone,adrenocorticotrophic hormone,and prolactin when they act on non-classical organs were summarized,defined by the novel concept of an“atypical pituitary hormone–target tissue axis.”This novel proposal explains the pathomechanisms of abnormal glucose and lipid metabolism,obesity,hypertension,fatty liver,and atherosclerosis while offering a more comprehensive and systematic insights into the coordinated regulation of environmental factors,genetic factors,and neuroendocrine hormones on human biological *** continued exploration of the physiology of the“atypical pituitary hormone–target tissue axis”could enable the identification of novel therapeutic targets for metabolic diseases.

关键词： thyroid-stimulating hormone follicle-stimulating hormone luteinizing hormone adrenocorticotrophic hormone prolactin

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双滚筒传动带式输送机的电动机功率平衡

东北大学学报（自然科学版） 2000年第5期21卷 520-523页

作者：邓永胜宋伟刚赵琛东北大学机械工程与自动化学院辽宁沈阳110006 鞍钢附企原料总厂辽宁鞍山114023

根据驱动系统输出转矩之和维持不变的条件 ,导出了以主要影响因素即输送带的弹性伸长率、传动滚筒直径偏差的相对值以及电动机外特性表示的电机功率不平衡度公式·分析了电动机功率不平衡的原因和主要影响因素对功率平衡的影响规律·分... 详细信息

根据驱动系统输出转矩之和维持不变的条件 ,导出了以主要影响因素即输送带的弹性伸长率、传动滚筒直径偏差的相对值以及电动机外特性表示的电机功率不平衡度公式·分析了电动机功率不平衡的原因和主要影响因素对功率平衡的影响规律·分析结果表明 :为了使电机功率分配相对均衡 ,在多滚筒传动的场合 ,输送带最好采用钢丝芯胶带 ;第 1滚筒的直径可以略大于第 2滚筒的直径·

关键词：双滚筒带式输送机功率不平衡度电动机驱动力功率分配

远射程风送式喷雾机气流场分布及喷雾特性试验

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农业工程学报 2017年第24期33卷 72-79页

作者：陈建泽宋淑然孙道宗洪添胜张龙华南农业大学工程学院广州510642 华南农业大学电子工程学院广州510642 国家柑橘产业技术体系机械研究室广州510642 广东省农情信息监测工程技术研究中心广州510642 广东省山地果园机械创新工程技术研究中心广州510642

由于远射程风送式喷雾机的空间风场及喷雾特性尚未明确,该文利用风速测量定位网架,进行了远射程风送式喷雾机空间风场特性试验和喷幅试验。试验结果发现,远射程风送式喷雾机轴心上的纵向时均风速随采样点距喷嘴距离的增加而衰减,两者呈... 详细信息

由于远射程风送式喷雾机的空间风场及喷雾特性尚未明确,该文利用风速测量定位网架,进行了远射程风送式喷雾机空间风场特性试验和喷幅试验。试验结果发现,远射程风送式喷雾机轴心上的纵向时均风速随采样点距喷嘴距离的增加而衰减,两者呈负对数关系,这一特征符合淹没射流的流速变化规律;远射程风送式喷雾机轴心方向同一采样点上的风速与风机供电频率之间呈线性正相关,决定系数最低为0.609 1;远射程风送式喷雾机的水平喷幅关于喷筒轴心方向左右对称;而垂直喷幅在喷筒轴心方向的上下方呈现为不对称;远射程风送式喷雾远射程风送式喷雾机的送风量及出风口气流的时均风速均与风机供电电源的频率成正比;采用纸卡法测量了喷雾机的水平作业幅宽,该试验样机的水平作业幅宽为22 m。卷吸引起的伯努利效应和附壁效应是形成垂直喷幅不对称的重要原因,采用喷筒仰角喷雾可消除此效应。研究结果为远射程风送式喷雾机的生产和使用提供理论基础与参考。

关键词：农业机械喷雾风速远射程风送空间风场喷幅附壁效应

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时空权重和边缘自适应去隔行

计算机学报 2007年第4期30卷 655-660页

作者：丁勇陆生礼时龙兴东南大学国家专用集成电路系统工程技术研究中心南京210096

为实现隔行扫描到逐行扫描的视频格式转换,文中提出了一种时空权重和边缘自适应的去隔行算法,主要包括4个同极性场运动估计、小角度边缘搜索、时空权重计算、自适应插值等.运动估计通过比较同极性场的像素块绝对值差和(SAD)与运动阈值... 详细信息

为实现隔行扫描到逐行扫描的视频格式转换,文中提出了一种时空权重和边缘自适应的去隔行算法,主要包括4个同极性场运动估计、小角度边缘搜索、时空权重计算、自适应插值等.运动估计通过比较同极性场的像素块绝对值差和(SAD)与运动阈值实现运动估计,并且利用前一场的运动信息进行鲁棒性处理,提高运动检测的精度.小角度边缘搜索采用自适应搜索半径的方法实现最小6°的小角度边缘检测.最后,通过时空权重自适应的插值算法实现去隔行处理,取得很好的处理效果.

关键词：运动估计边缘搜索时空权重自适应插值去隔行

辐射穿透率在锅炉受热面壁温计算中的应用与研究

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动力工程 2007年第5期27卷 687-690页

作者：李晋胡兴胜陈朝松上海发电设备成套设计研究院上海200240

辐射穿透率在锅炉受热面壁温计算中很重要,但它对锅炉受热面计算壁温准确性的影响却未能引起充分的关注。从辐射穿透率的定义出发,推导出适合工程计算的公式,并将该研究结果应用于工程改造项目中,取得了良好的预期效果,在使用范围和精... 详细信息

辐射穿透率在锅炉受热面壁温计算中很重要,但它对锅炉受热面计算壁温准确性的影响却未能引起充分的关注。从辐射穿透率的定义出发,推导出适合工程计算的公式,并将该研究结果应用于工程改造项目中,取得了良好的预期效果,在使用范围和精度上均能满足锅炉设计计算和校核计算的要求。

关键词：能源与动力工程锅炉辐射穿透率壁温计算超温积分