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Debaryomyces hansenii supplementation in low fish meal diets promotes growth,modulates microbiota and enhances intestinal condition in juvenile marine fish

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Journal of Animal Science and Biotechnology 2024年第1期15卷 253-276页

作者： Ignasi Sanahuja Alberto Ruiz Joana P.Firmino Felipe E.Reyes-López Juan B.Ortiz-Delgado Eva Vallejos-Vidal lluis Tort Dariel Tovar-Ramírez Isabel M.Cerezo Miguel A.Moriñigo Carmen Sarasquete Enric Gisbert Aquaculture Program Institute of Agrifood Research and Technology(IRTA)La Rapita 43540Spain Centro de Biotecnologia Acuicola Universidad de Santiago de ChileSantiagoChile Instituto de Ciencias Marinas de Andalucia(ICMAN-CSIC) Avda.Republica Saharaui no 2Campus Universitario Rio San PedroPuerto RealCadiz 11510Spain Nucleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronomicas Facultad de Medicina Veterinaria y AgronomiaUniversidad de Las AmericasSantiagoChile Department of Cell Biology Physiologyand ImmunologyUniversitat Autonoma de BarcelonaBarcelonaSpain Centro de Investigaciones Biologicas del Noroeste SC CIBNORLa PazMexico Department of Microbiology Instituto de Biotecnologia Y Desarrollo Azul(IBYDA)Faculty of SciencesUniversity of Malaga29010 MalagaSpain SCBI Bioinformatic UnitUniversity of Malaga29590 MalagaSpain

Background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed *** hansenii is a yeast species that can be used as a probiotic in aquaculture due to its capacity to i)promote cell proliferation and differen-tiation,ii)have immunostimulatory effects,iii)modulate gut microbiota,and/or iv)enhance the digestive *** provide inside into the effects of *** on juveniles of gilthead seabream(Sparus aurata)condition,we inte-grated the evaluation of the main key performance indicators coupled with the integrative analysis of the intestine condition,through histological and microbiota state,and its transcriptomic *** After 70 days of a nutritional trial in which a diet with low levels of fishmeal(7%)was supplemented with 1.1%of ***(17.2×10^(5) CFU),an increase of ca.12%in somatic growth was observed together with an improve-ment in feed conversion in fish fed a yeast-supplemented *** terms of intestinal condition,this probiotic modu-lated gut microbiota without affecting the intestine cell organization,whereas an increase in the staining intensity of mucins rich in carboxylated and weakly sulphated glycoconjugates coupled with changes in the affinity for certain lectins were noted in goblet *** in microbiota were characterized by the reduction in abundance of several groups of Proteobacteria,especially those characterized as opportunistic *** microarrays-based transcrip-tomic analysis found 232 differential expressed genes in the anterior-mid intestine of ***,that were mostly related to metabolic,antioxidant,immune,and symbiotic *** Dietary administration of *** enhanced somatic growth and improved feed efficiency param-eters,results that were coupled to an improvement of intestinal condition as histochemical and transcriptomic tools *** probiotic ye

关键词： Debaryomyces hansenii Intestine condition Low fish meal diet Microbiota Transcriptomics Yeast probiotic

Existence, Uniqueness and Functoriality of the Perfect Locality over a Frobenius P-Category

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Algebra Colloquium 2016年第4期23卷 541-622页

作者： lluis Puig CNRS Institut de Mathematiques de Jussieu 6 Av Bizet 94340 Joinville-le-Pont France

Let p be a prime, P a finite p-group and F- a Frobenius P-category. The question on the existence of a suitable category L^scextending the full subcategory of F over the set of F-selfcentralizing subgroups of P goes back to Dave Benson in 1994. In 2002 Carles Broto, Ran Levi and Bob Oliver formulate the existence and the uniqueness of the category L^sc in terms of the annulation of an obstruction 3-cohomology element and of the vanishing of a 2-cohomology group, and they state a sufficient condition for the vanishing of these n-cohomology groups. Recently, Andrew Chermak has proved the existence and the uniqueness of L^sc via his objective partial groups, and Bob Oliver, following some of Chermak＇s methods, has also proved the vanishing of those n-cohomology groups for n 〉1, both applying the Classification of the finite simple groups. Here we give direct proofs of the existence and the uniqueness of L^sc; moreover, in [11] we already show that L^sc can be completed in a suitable category L extending F and we also prove some functoriality of this correspondence.

关键词： group Frobenius P-category locality

Categorizations of Limits of Grothendieck Groups over a Frobenius P-Category

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Algebra Colloquium 2022年第4期29卷 541-594页

作者： lluis Puig Carrer de La Cort 16 Vilafranca del PenedesFrance

In[Frobenius Categories Versus Brauer Blocks,Progress in Math.,274]and in[Ordinary Grothendieck groups of a Frobenius P-category,Algebra Colloq.18(2011)1-76],we consider suitable inverse limits of Grothendieck groups of categories of modules in characteristics p and zero,obtained from a folded Frobenius P-category(F,aut_(F)sc),which covers the case of the Frobenius P-categories associated with blocks;moreover,in[Beyond a question of Markus Linckelmann,***/abs/1507.04278]we show that a folded Frobenius P-category is actually equivalent to the choice of a regular central k^(*)-extension F^(SC) of F^(SC) ***,taking advantage of the existence of a perfect F^(SC) -locality P^(SC) we exhibit those inverse limits as the true Grothendieck groups of the categories of K_(*)G-and k_(*)G-modules for a suitable k_(*)-group G associated to the k^(*)-category P^(SC) obtained from P^(SC) and F^(SC) .It depends on a vanishing cohomology result,given with more generality intheAppendix.

关键词： Frobenius category Grothendieckgroup perfect locality

The Hecke Algebra of a Frobenius P-Category

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Algebra Colloquium 2014年第1期21卷 1-52页

作者： lluis Puig CNRS Institut de Mathematiques de Jussieu 6 Av Bizet 94340 Joinville-le-Pont France

We introduce a new avatar of a Frobenius P-category F under the form of a suitable subring HF of the double Burnside ring of P -- called the Hecke algebra of F- where we are able to formulate：（i） the generalization to a Frobenius P-category of the Alperin Fusion Theorem, （ii） the ＂canonical decomposition＂ of the morphisms in the exterior quotient of a Frobenius P-category restricted to the selfcentralizing objects as developed in chapter 6 of [4], and （iii） the ＂basic P × P-sets＂ in chapter 21 of [4] with its generalization by Kari Ragnarsson and Radu Stancu to the virtual P ×P-sets in [6]. We also explain the relationship with the usual Hecke algebra of a finite group.

关键词： finite group Frobenius category Hecke algebra Burnside ring

Human prostate cancer heterotransplants： a review on this experimental model

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Asian Journal of Andrology 2010年第4期12卷 509-518页

作者： lluis A. Lopez-Barcons Stanley S. Scott Cancer Center Louisiana State University Health Sciences Center New Orleans LA 70112 USA

A common model used for preclinical research was in vitro human tumor cell culture. An alternative model was the direct implantation of a unique patient＇s tumor biopsy specimens into immunodeficient host mice. Published data from PubMed （http：//***） and Current Contents Connect databases （http：//***/ products_services/science/science_roducts/a-z/current_contents_connect） were reviewed. Prostate cancer （PCa） heterotransplantation was evaluated using histopathology, morphology, cell differentiation, DNA content, tumor marker expression, metastases, tumor kinetics, tumor take rate and tumor vasculature in the first tumor heterotransplant. The heterotransplanted tumor retained the biological properties of the original tumor, such as morphology, degree of differentiation, pathology, secretory activity, expression of tumor markers and human vasculature. Human PCa heterotransplants have considerable experimental advantages over cell culture following xenotransplantation.

关键词： cancer experimental model heterotransplant nude mice prostate xenotransplant

A Correction to the Uniqueness of a Partial Perfect Locality over a Frobenius P-Category

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Algebra Colloquium 2019年第4期26卷 541-559页

作者： lluis Puig Jiping Zhang CNRS Institut de Mathematiques de Jussieu 6 Av Bizet94340 Joinville-le-PontFrance 不详

Let p be a prime,P a finite p-group and F a Frobenius ***[Existcnee,uniqueness and functoriality of the perfect locality over a Frobenius P-category,Algebra Colloq.23(2016)541-622],we claimed the uniqueness of the partial perfect locality over any up-closed set X of J--selfcentralizing subgroups of P,but recently Bob Oliver exhibits some counter-cxamplcs,demanding some revision of our *** this note we show that,up to replacing the perfect localities by the extendable perfect localities over any up-closed set X of J7-selfcentralizing subgroups of P,our arguments are correct,still proving the existence and the uniqueness of the perfect J730-locality,since it is *** take advantage of this revision to simplify some of our arguments.

关键词： group P-category local structure

Small-cell neuroendocrine carcinoma of the prostate： are heterotransplants a better experimental model？

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Asian Journal of Andrology 2010年第3期12卷 308-314,I0007页

作者： lluis-A. Lopez-Barcons Stanley S. Scott Cancer Center Louisiana State University Health Sciences Center New Orleans LA 70112 USA

Small-cell neuroendocrine carcinoma of the prostate （SCNCP） is an uncommon type of prostate cancer. However, it is of clinical importance because it is one of the most aggressive tumors of the prostate with a very poor prognosis. There exist few artificially cultured tumor cell lines to study SCNCE Then, another approach to that study consists in the use of fresh tumor tissue obtained from patients and its heterotransplantation into host mice. The purpose of this review is to integrate data from more than 20 years of heterotransplantation research in the study of small-cell neuroendocrine carcinoma of the prostate （SCNCP）. Heterotransplantation has provided data regarding the histopathology, karyotype, DNA content, cell cycle frequency, tumor markers, androgen receptor expression, metastasis and take rate of this prostate disease. When possible, comparisons between original in situ specimens removed from patients and heterotransplanted tissue from host mice have been made. There are advantages, as well as limitations, that have been identified for SCNCP heterotransplants versus xenotransplantation of cultured cells. Overall, heterotransplanted tumors are better than conventional tumor xenografts at retaining tumor morphology, pathology, secretory activity and expression of tumor markers of the patient＇s original specimen. Furthermore, heterotransplanted tissue preserves the three-dimensional tumor architecture of the prostate to maintain critical stromal-epithelial cell interactions.

关键词： heterotransplant nude mice prostate small-cell neuroendocrine carcinoma xenotransplant

Generalized Hamming weights and equivalences of codes

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Science China Mathematics 2003年第5期46卷 690-695页

作者：樊恽刘宏伟 lluis Puig Department of Mathematics Wuhan University. Wuhan 430072 Department of Mathematics Hubei University Wuhan 430062 China Department of Mathematics Wuhan University Wuhan 430072 Department of Mathematics Central China Normal University Wuhan 430079 China CNRS Universite de Paris 7 6 Avenue Bizet Joinville le Pont 94340 France

It is proved that any linear isomorphism between two linear codes which preserves a generalizedHamming weight is a monomial equivalence, which is an extension of a theorem of MacWilliams.

关键词： equivalence, generalized Hamming weight, isometry.

Human sperm chromatin epigenetic potential： genomics, proteomics, and male infertility

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Asian Journal of Andrology 2015年第4期17卷 601-609页

作者： ludit Castillo Josep Maria Estanyol Josep lluis Ballesca Rafael Oliva Human Genetics Research Group IDIBAPS Faculty of Medicine University of Barcelona Casanova 143 08036 Barcelona Spain Biochemistry and Molecular GeneticsService Biomedical Diagnostic Centre Hospital Clinic Villarroel 170 08036 Barcelona Spain Proteomics Unit Scientific and Technological Centres of the Universityof Barcelona (CCiTUB) Casanova 143 08036 Barcelona Spain Clinic Institute of Gynaecology Obstetrics and Neonatology Hospital Clinic Villarroel 170 08036Barcelona Spain.

The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation. In addition, recent sperm chromatin genome-wide dissection studies indicate the presence of a differential distribution of the genes and repetitive sequences in the protamine-condensed and histone-condensed sperm chromatin domains, which could be potentially involved in regulatory roles after fertilization. Interestingly, recent proteomic studies have shown that sperm chromatin contains many additional proteins, in addition to the abundant histones and protamines, with specific modifications and chromatin affinity features which are also delivered to the oocyte. Both gene and protein signatures seem to be altered in infertile patients and, as such, are consistent with the potential involvement of the sperm chromatin landscape in early embryo development. This present work reviews the available information on the composition of the human sperm chromatin and its epigenetic potential, with a particular focus on recent results derived from high-throughput genomic and proteomic studies. As a complement, we provide experimental evidence for the detection of phosphorylations and acetylations in human protamine 1 using a mass spectrometry approach. The available data indicate that the sperm chromatin is much more complex than what it was previously thought, raising the possibility that it could also serve to transmit crucial paternal epigenetic information to the embryo.

关键词： genomics male infertility proteomics sperm chromatin sperm epigenetics