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伴生不同作物对主栽番茄植株根系内生微生物群落结构的影响

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华中农业大学学报 2024年第1期43卷 31-39页

作者：覃欣仪何丽珍肖可卓庞师婵宋静静杨尚东广西大学农学院/植物科学国家级实验教学示范中心南宁530004 广西南亚热带农业科学研究所崇左532415 广西北部湾海洋生物多样性养护重点实验室/北部湾大学海洋学院钦州535011

为为解决番茄连作障碍、构建番茄可持续发展的生态栽培技术体系,设置番茄伴生生菜(A)、苋菜(B)、菜心(C)、葱(D)、薄荷(E)以及番茄单作(F)处理,在相同环境条件下进行同样栽培管理,利用Illumina MiSeq高通量测序平台,分析不同作物伴生及... 详细信息

为为解决番茄连作障碍、构建番茄可持续发展的生态栽培技术体系,设置番茄伴生生菜(A)、苋菜(B)、菜心(C)、葱(D)、薄荷(E)以及番茄单作(F)处理,在相同环境条件下进行同样栽培管理,利用Illumina MiSeq高通量测序平台,分析不同作物伴生及番茄单作处理下根系内生微生物多样性与群落组成。结果显示:伴生及单作番茄植株根系共有的排名前5的优势细菌属为链霉菌属(Streptomyces)、Burkholderia-Caballeronia-Paraburkholderia、德沃斯氏菌属(Devosia)、类诺卡氏菌属(Nocardioides)、马赛菌属(Massilia);番茄伴生生菜(A)特有的优势内生细菌属为新草小螺菌属(Noviherbaspirillum),番茄伴生苋菜(B)特有的优势内生细菌属为游动放线菌属(Actinoplanes);番茄伴生葱(D)特有的优势内生细菌属为爬管菌属(herpetosiphon),番茄伴生薄荷(E)特有的优势内生细菌属为微杆菌属(Microbacterium),番茄单作(F)特有的优势内生细菌属包括芽孢杆菌属(Bacillus)、栖大理石菌属(Marmoricola)和糖霉菌属(Glycomyces);伴生及单作处理番茄共有的优势真菌属为油壶菌属(Olpidium)、unclassified_o_Sordariales、unclassified_p_Ascomycota,番茄伴生生菜(A)特有的优势内生真菌属为Immersiella,番茄伴生苋菜(B)特有的优势内生真菌包括念珠菌属(Candida)、unclassified_c_Agaricomycetes和Phialemonium,番茄伴生菜心(C)特有的优势内生真菌包括Rhizophagus、Plectosphaer⁃ella、Geminibasidium,番茄伴生葱(D)特有的优势内生真菌包括unclassified_p_Chytridiomycota、unclassified_f_Ceratobasidiaceae、Ceratorhiza、unclassified_o_Boletales、unclassified_p_Basidiomycota,番茄单作(F)特有的优势内生真菌属为赤霉属(Gibberella)。结果表明,与番茄单作相比,番茄伴生不同作物使主栽番茄根系优势内生细菌和内生真菌属组成发生了变化,伴生条件下主栽番茄根系均富集了特异的优势内生细菌和真菌门、属。伴生富集的特异优势内生细菌或真菌门、属组成具有提升主栽番茄植株抵御环境生物或非生物胁迫的潜力。

关键词：番茄伴生根系内生微生物连作障碍环境胁迫

Ruthenium Polypyridyl Complexes Combined with Natural Killer Cells Enhanced Immunotherapeutic Efficacy in Breast Cancer Cells

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Ruthenium Polypyridyl Complexes Combined with Natural Killer...

Q-homotopy analysis method for time-fractional Newell–Whitehead equation and time-fractional generalized Hirota–Satsuma coupled KdV system

第十一届全国化学生物学学术会议

作者： Qi Chen lizhen he Tianfeng Chen Department of Chemistry Jinan University

Natural killer(NK) cells are important immune cells that show cytotoxic activity against a variety of tumor cell ***,we report that a ruthenium polypyridyl complexes(RuPOP) combined with NK cells could enhanced immunotherapeutic efficacy in human breast carcinoma cell line(MDA-MB-231).We found that RuPOP not only promoted the secretion of IL-6,IL-12,IL-15 and inhibit the secretion of IL-10 to enhance the anti-tumor activity of NK cells,but also up-regulated the expression MICA,ULBP1,ULBP2,ULBP4 proteins in MDA-MB-231 cells,which enhanced the recognition of tumor cells by NK cells,and inhibited the production of immune *** proteomic analysis of RuPOP targets in MDA-MB-231 cells,it was found that 26 of the 68 target proteins captured were immune-related,and 9 of them were closely related to NK *** studies revealed that RuPOP combined with NK cells enhanced the accumulation of ROS in MDA-MA-231 cells,which caused DNA damage,enhanced the expression of apoptosis-inducible proteins(FasL) and TNF related apoptosis inducing ligands(TRAIL),which rendered the tumor cells into a programmed apoptotic *** data suggest that RuPOP enhances the immunotherapy effect of NK cells by promoting the secretion of cytokines,up-regulating the expression of NKG2D ligand proteins and activating TRAIL/TRAIL-R and Fas/FasL signaling pathways.

关键词： Natural killer cells Ruthenium polypyridyl complexes Immunotherapy

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Communications in Theoretical Physics 2024年第3期76卷 70-83页

作者： Di Liu Qiongya Gu lizhen Wang Center for Nonlinear Studies School of MathematicsNorthwest UniversityXi'an710127China

In this paper,two types of fractional nonlinear equations in Caputo sense,time-fractional Newell–Whitehead equation(FNWE)and time-fractional generalized Hirota–Satsuma coupled KdV system(HS-cKdVS),are investigated by means of the q-homotopy analysis method(q-HAM).The approximate solutions of the proposed equations are constructed in the form of a convergent series and are compared with the corresponding exact *** to the presence of the auxiliary parameter h in this method,just a few terms of the series solution are required in order to obtain better *** the sake of visualization,the numerical results obtained in this paper are graphically displayed with the help of Maple.

关键词： fractional Newell-Whitehead equation fractional generalized Hirota-Satsuma coupled KdV system approximate solution q-homotopy analysis method

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单原子催化剂的生物医学应用

高等学校化学学报 2020年第12期41卷 2690-2709页

作者：袁中文贺利贞陈填烽暨南大学化学系广州510632

单原子催化剂(SACs)具有100%的原子利用率及充分暴露的原子金属活性位点,其催化活性和选择性更具优势,已广泛应用在化学、能源及环境等领域.近年来,SACs在生物医学领域也引起了广泛关注.本文综述了SACs在肿瘤治疗、抗菌、抗氧化和生物... 详细信息

单原子催化剂(SACs)具有100%的原子利用率及充分暴露的原子金属活性位点,其催化活性和选择性更具优势,已广泛应用在化学、能源及环境等领域.近年来,SACs在生物医学领域也引起了广泛关注.本文综述了SACs在肿瘤治疗、抗菌、抗氧化和生物传感等生物医学领域的应用及研究进展,并简要总结了SACs未来应用的挑战和机遇,为合理设计多性能的SACs提供了可行策略.

关键词：单原子催化剂肿瘤治疗抗菌抗氧化生物传感

Which Neighborhoods Have Easier Access to Online Home Delivery Services?A Spatiotemporal Accessibility Analysis in Nanjing,China

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Chinese Geographical Science 2024年第4期34卷 722-738页

作者： KONG Yu ZheN Feng ZHANG Shanqi SheN lizhen School of Architecture and Urban Planning Nanjing UniversityNanjing 210093China Provincial Engineering Research Center of Smart City Planning and Digital Governance Nanjing 210093China

The rise in online home delivery services(OHDS)has had a significant impact on how urban services are supplied and used in recent *** on the spatial accessibility of OHDS are emerging,but few is known about the temporal dimension of OHDS accessibility as well as the geographic and socioeconomic differences in the spatiotemporal accessibility of *** study measures the spatiotemporal accessibility of four types of OHDS,namely leisure,fresh and convenient,medical,and catering *** geographic and socioeconomic disparities in the spatiotemporal accessibility of these four types of OHDS are then identified using spatial statistical methods and the Kruskal-Wallis test(K-W test).The case study in Nanjing,China,suggests that:1)spatiotemporal accessibility better reflects the temporal variation of OHDS accessibility and avoids overestimation of OHDS accessibility when only considering its spatial dimension.2)The spatiotemporal accessibility of OHDS varies geographically and *** located in the main city or neighborhoods with higher housing prices,higher population density,and higher point of interest(POI)mix have better OHDS spatiotemporal *** study contributes to the understanding of OHDS accessibility from a spatiotemporal perspective,and the empirical insights can assist policymakers in creating intervention plans that take into account variations in OHDS spatiotemporal accessibility.

关键词： online home delivery services(OHDS) spatiotemporal accessibility neighborhoods accessibility differences Nanjing City China

IoV environment exploring coordination:A federated learning approach

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Digital Communications and Networks 2024年第1期10卷 135-141页

作者： Tong Ding Lei Liu Yi Zhu lizhen Cui Zhongmin Yan School of Software Shandong UniversityJinan250101China

Exploring open fields with coordinated unmanned vehicles is popular in academia and *** of the most impressive applicable approaches is the Internet of Vehicles(lov).The IoV connects vehicles,road infrastructures and communication facilities to provide solutions for exploration ***,the coordination of acquiring information from multi-vehicles may risk data *** this end,sharing high-quality experiences instead of raw data has become an urgent *** paper employs a Deep Reinforcement Learning(DRL)method to enable IoVs to generate training data with prioritized experience and states,which can support the IoV to explore the environment more ***,a Federated Learning(FL)experience sharing model is established to guarantee the vehicles'*** numerical results show that the proposed method presents a better successful sharing rate and a more stable convergence within the comparison of fundamental *** experiments also suggest that the proposed method could support agents without full information to achieve the tasks.

关键词： Internet of vehicle Deep reinforcement learning Federated learning Data privacy

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丙烯热反应生成甲基环戊烷的理论探讨

物理化学学报 1999年第4期15卷 308-312页

作者：何丽针陈光巨刘若庄北京师范大学化学系

在UHF／3-21G水平上，应用从头算分子轨道法和能量梯度技术，并用Mller-Plesset二级微扰理论对能量进行了相关能校正，研究了丙烯在800K热反应形成甲基环戊烷的反应机理．求得该反应分三步进行：（1）两分子丙烯相互作用产生1，4-双自... 详细信息

在UHF／3-21G水平上，应用从头算分子轨道法和能量梯度技术，并用Mller-Plesset二级微扰理论对能量进行了相关能校正，研究了丙烯在800K热反应形成甲基环戊烷的反应机理．求得该反应分三步进行：（1）两分子丙烯相互作用产生1，4-双自由基中间体；（2）1，4-双自由基中间体经氢迁移过程生成1，5-双自由基中间体；（3）1，5-双自由基中间体闭环形成甲基环戊烷．理论计算所得的机理与实验工作者推测一致．

关键词：丙烯甲基环戊烷从头算热反应机理

EFFICIENT SPECTRAL METHODS FOR EIGENVALUE PROBLEMS OF The INTEGRAL FRACTIONAL LAPLACIAN ONABALLOFANYDIMENSION

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Journal of Computational Mathematics 2024年第4期42卷 1032-1062页

作者： Suna Ma Huiyuan Li Zhimin Zhang Hu Chen lizhen Chen College of Science Nanjing University of Posts and TelecommunicationsNanjingChina State Key Laboratory of Computer Science/Laboratory of Parallel Computing Institute of SoftwareChinese Academy of SciencesBeijingChina Department of Mathematics Wayne State UniversityDetroitUSA School of Mathematical Sciences Ocean University of ChinaQingdaoChina Beijing Computational Science Research Center BeijingChina

An efficient spectral-Galerkin method for eigenvalue problems of the integral fractional Laplacian on a unit ball of any dimension is proposed in this *** symmetric positive definite linear system is retained explicitly which plays an important role in the numerical *** a sharp estimate on the algebraic system's condition number is established which behaves as N4s with respect to the polynomial degree N,where 2s is the fractional derivative *** regularity estimate of solutions to source problems of the fractional Laplacian in arbitrary dimensions is firstly investigated in weighted Sobolev *** the regularity of eigenfunctions of the fractional Laplacian eigenvalue problem is readily ***,rigorous error estimates of the eigenvalues and eigenvectors are *** experiments are presented to demonstrate the accuracy and efficiency and to validate the theoretical results.

关键词： Integral fractional Laplacian Spectral method Eigenvalue problem Regularity analysis Error estimate

高职高专教学网站的建设与实践——以有机化学教学为例

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科技管理研究 2011年第7期31卷 184-186页

作者：何丽针江西医学院上饶分院江西上饶334000

以有机化学教学网站的建设和实践为案例,对高职高专教学网站建设和实践进行研究,分析教学网站建设的目的和意义,探讨教学网站建设的基本思路和制作方法,以其达到推动高职高专教育观念、教育模式和教学方式的改革。

关键词：高职高专网站建设与实践教学