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Chinese Chemical Letters 2019年第6期30卷 1273-1276页

作者： lizhen qiao Man Song Aifang Geng Shuang Yao School of Chemical and Environmental Engineering Changchun University of Science and Technology Changchun 130022 China School of Chemistry and Chemical Engineering Tianjin University of Technology Tianjin 300384 China

A high-nuclear Co-V-O cluster was firstly isolated by lacunary polyoxoanion, resulting in the high-nuclear mixed metal-oxo cluster-containing polyoxometalate (POM), K4Na28[{Co4(O-H)3(VO4)}4(SiW9O34)4]· 66H2O (1). In 1, the{Co4(O-H)3(VO4)}4{Co16-V4}core, composed of a{Co4O4}cubane, four{Co4(OH)3}qusi-cubanes and four VO4 units, was stabilized by four lacunary A-α-{SiW9O34} units. Photocatalytic study reveals that 1 exhibits excellent photocatalytic activity for CO2-to-CO conversion with high selectivity under visible light irradiation. The turnover number (TON) and turnover frequency (TOF) reaches as high as 10492 and 0.29 s^-1, respectively. Compound 1 represents the first high nuclear TM cluster-containing POM (TM=transition-metal) with efficient visible light catalytic activity for CO2 reduction, and its photocatalytic activity is much higher than those of most reported molecular catalysts. Photoluminescence spectroscopy study reveals that photoexcitation of Ru-photosensitizer is followed by an efficient electron transfer to POMs to reduce CO2.

关键词： Polyoxometalate High-nuclear cobalt cluster Photocatalysis CO2 reduction Photosensitizer

正念减压联合渐进式肌肉放松技术在幽闭恐惧症病人磁共振检查中的应用

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护理研究 2020年第14期34卷 2577-2580页

作者：周意肖运平乔丽珍柳州市人民医院广西545001

[目的]探讨正念减压和渐进式肌肉放松技术在幽闭恐惧症病人磁共振(MRI)检查中的应用效果。[方法]选择2017年10月—2019年10月在柳州市人民医院行磁共振检查中出现幽闭恐惧症的病人60例,按照抛硬币法随机分为两组各30例。对照组给予常规... 详细信息

[目的]探讨正念减压和渐进式肌肉放松技术在幽闭恐惧症病人磁共振(MRI)检查中的应用效果。[方法]选择2017年10月—2019年10月在柳州市人民医院行磁共振检查中出现幽闭恐惧症的病人60例,按照抛硬币法随机分为两组各30例。对照组给予常规心理护理;观察组在常规心理护理基础上给予正念减压与渐进式放松技术,比较两组干预前后焦虑自评量表(SAS)评分、情绪状态评定量表(POMS)评分及病人检查时严重自主神经症状出现情况、磁共振检查完成情况、病人对护士的满意度。[结果]干预后,观察组病人SAS评分、POMS量表情绪纷乱总分(TMD)低于对照组病人(P<0.05);观察组病人检查时严重自主神经症状发生情况少于对照组病人(P<0.05);观察组病人完成检查情况、对护士满意度高于对照组病人(P<0.05)。[结论]正念减压联合渐进式肌肉放松技术有助于缓解幽闭恐惧症病人的恐惧心理,使病人配合医护人员顺利完成MRI检查。

关键词：磁共振幽闭恐惧症正念减压渐进式肌肉放松焦虑情绪状态自主神经症状满意度

基于低共熔溶剂的悬浮固化分散液液微萃取测定水体中4种邻苯二甲酸酯

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分析试验室 2023年第7期42卷 910-916页

作者：姚旺徐若竹孙瑞婷乔利珍大连理工大学化工学院盘锦分院盘锦124221 大连理工大学精细化工国家重点实验室大连116023

设计并制备了6种可低温固化的疏水性低共熔溶剂(DESs)。将其作为萃取剂,建立了一种悬浮固化分散液液微萃取(SFO-DLLME)方法,结合气相色谱法(GC),对水体环境中4种邻苯二甲酸酯(PAEs)进行富集测定。最佳萃取条件为:50μL麝香草酚和癸酸以... 详细信息

设计并制备了6种可低温固化的疏水性低共熔溶剂(DESs)。将其作为萃取剂,建立了一种悬浮固化分散液液微萃取(SFO-DLLME)方法,结合气相色谱法(GC),对水体环境中4种邻苯二甲酸酯(PAEs)进行富集测定。最佳萃取条件为:50μL麝香草酚和癸酸以摩尔比2∶1形成的低共熔溶剂(DES-4)作为萃取剂,超声5 min,样品溶液中NaCl浓度为2%(w/V),pH 5。在优化条件下,4种PAEs在5~800μg/L范围内呈良好的线性关系,相关系数R^(2)为0.9921~0.9985,检出限为1~2.5μg/L。将建立的方法应用于市售塑料瓶装矿泉水、自来水和河水样品中4种PAEs的测定,3个浓度水平下加标回收率为75.5%~119.0%,相对标准偏差为0.43%~8.9%。该方法可用于水体环境中4种PAEs的富集测定。

关键词：低共熔溶剂分散液液微萃取悬浮固化邻苯二甲酸酯

5%复方利多卡因乳膏外用联合心理干预对造影剂渗出患者的临床观察

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国际护理学杂志 2019年第18期38卷 2916-2919页

作者：宋朝晖李惠平许晓蓉乔丽珍柳州市人民医院供应室广西柳州545006 柳州市人民医院门诊部广西柳州545006 柳州市人民医院放射科广西柳州545006

目的观察5%复方利多卡因乳膏外用联合心理干预对造影剂渗出疗效。方法对30例CT检查过程中造影剂渗出的患者给予5%复方利多卡因乳膏外用及心理干预。观察局部症状缓解有效率、显效率、焦虑缓解率、患者依从性变化。结果治疗后局部症状缓... 详细信息

目的观察5%复方利多卡因乳膏外用联合心理干预对造影剂渗出疗效。方法对30例CT检查过程中造影剂渗出的患者给予5%复方利多卡因乳膏外用及心理干预。观察局部症状缓解有效率、显效率、焦虑缓解率、患者依从性变化。结果治疗后局部症状缓解有效率、显效率分别为96.70%、53.30%;干预后患者状态焦虑缓解,其中低特质焦虑组患者状态焦虑缓解率高于高特质焦虑组;干预后患者依从性提高。结论5%复方利多卡因乳膏外用是治疗造影剂渗出有效的方法,联合心理干预进一步改善患者不良心理情绪与依从性,提高治疗效果;特质焦虑状态对心理干预的疗效有一定影响。

关键词：造影剂渗出 5%复方利多卡因乳膏状态-特质焦虑心理干预

Responses of osteoblasts under varied tensile stress types induced by stretching basement materials

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International Journal of Smart and Nano Materials 2024年第2期15卷 279-295页

作者： Xuezheng Geng qiao Li Yan Yao lizhen Wang Yubo Fan Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical EngineeringKey Laboratory of Biomechanics and Mechanobiology(Beihang University)Ministry of EducationBeijingChina School of Engineering Medicine Beihang UniversityBeijingChina

Osteoblasts are mechanosensitive *** stress with different conditions,including loading time,frequency,magnitude,*** cause varied responses in ***,it was not clarified that the effect of the loading types on the *** this study,we focused on the effect of varied tensile stress types on osteoblasts,including isotropic stretch,biaxial stretch,and uniaxial stretch with the negative ratio of transverse strain to axial strain(NR)-1,0,and 0.2 *** proliferation was determined to be most efficient when stimulated by 6%strain at a frequency of 1 Hz and a negative value of 0 for 1 h/*** varied strain resulted in a thickening of the F-actin cytoskeleton and a thinning of the *** flattening caused Yes-associated protein(YAP)to be transported to the *** was suggested that the influence of loading types on the mechanobiology responses must be *** mechanism of cell mechanical sensitivity under varied loading types was explored,which would provide good sugges-tions for designing microstructures to control deformation patterns in bone tissue engineering.

关键词： MC3T3-E1 tensile stress negative poisson’s ratio cell proliferation YAP

不同剂型利多卡因外用对碘造影剂外渗治疗效果的比较

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现代医学 2019年第4期47卷 411-414页

作者：宋朝晖李惠平许小蓉乔丽珍柳州市人民医院供应室广西柳州545006 柳州市人民医院门诊部广西柳州545006 柳州市人民医院放射科广西柳州545006

目的:观察不同剂型利多卡因局部外用治疗碘造影剂渗出的效果。方法:将80例CT检查过程中造影剂渗出的患者采用区组随机法分为A组(使用50%硫酸镁溶液)、B组(使用2%利多卡因溶液)、C组(使用2%利多卡因胶浆)、D组(使用5%复方利多卡因乳膏) ... 详细信息

目的:观察不同剂型利多卡因局部外用治疗碘造影剂渗出的效果。方法:将80例CT检查过程中造影剂渗出的患者采用区组随机法分为A组(使用50%硫酸镁溶液)、B组(使用2%利多卡因溶液)、C组(使用2%利多卡因胶浆)、D组(使用5%复方利多卡因乳膏) 4组外用药物治疗,每组20例。观察4组治疗有效率、显效率、起效时间及治愈时间。结果:A、B、C、D组有效率依次为85%、90%、90%、95%,显效率依次为15%、45%、50%、60%,起效时间依次为(7. 5±2. 5)、(6. 0±2. 1)、(4. 7±1. 8)、(3. 6±1. 5) h,治愈时间依次为(36. 5±5. 4)、(32. 6±4. 2)、(29. 2±3. 8)、(23. 6±4. 3) h;4组有效率差异无统计学意义(P> 0. 05),B、C、D组显效率均高于A组(P <0. 05),A、B、C、D组起效时间、治愈时间依次递减(P <0. 05)。结论:相比50%硫酸镁溶液及2%利多卡因溶液,5%复方利多卡因乳膏、2%利多卡因胶浆外用治疗碘造影剂渗出具有起效快、使用便利的优势,值得进一步研究及推广使用。

关键词：碘造影剂渗出利多卡因不同剂型

Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent

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Medicine in Novel Technology and Devices 2024年第2期22卷 19-28页

作者： Lin Zhu qiao Li Yuanming Gao lizhen Wang Yubo Fan Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing100083China School of Engineering Medicine Beihang UniversityBeijing100191China

Background:Mg alloys have attractive properties,including biocompatibility,biodegradability,and ideal mechanical ***,Mg alloys are regarded as one of the promising candidates for manufacturing ureteral *** study proposed a multi-objective optimization method based on the Kriging surrogate model,NSGA-III,and finite element analysis to improve the degradation performance of Mg alloy ureteral ***:The finite element model for the degradation of Mg alloy ureteral stents has been established to compare the degradation performance of the stents under different *** hypercube sampling was adopted to generate train sample points in the design ***,the Kriging surrogate model was constructed between strut parameters and stent degradation *** NSGA-III was utilized to determine the optimal solution in the global design ***:The optimized stent achieved 5.52degradation uniformity(M),10degradation time(DT),and 4work time(FT).The errors between the Kriging surrogate model and the finite element calculation results were less than 6%.Conclusion:The optimized stent achieved better degradation *** degradation behavior of stents was dependent on the design *** multi-objective optimization method based on the Kriging surrogate model and finite element analysis was effective in stent design optimization problems.

关键词： Mg alloys ureteral stent Kriging surrogate model NSGA-III Multi-objective optimization Degradation model

Gut microbiota remodeling drived by dietary millet protein prevents the metabolic syndrome

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Food Science and Human Wellness 2024年第4期13卷 1987-2001页

作者： Shuhua Shan Ruopeng Yin Jiangying Shi lizhen Zhang Jiaqi Zhou Qinqin qiao Xiushan Dong Wenjing Zhao Zhuoyu Li Institute of Biotechnology Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of EducationShanxi UniversityTaiyuan 030006China School of Life Science Shanxi UniversityTaiyuan 030006China Shanxi Bethune Hospital Shanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuan 030032China Department of Biology Biological Science and Technology CollegeTaiyuan Normal UniversityJinzhong 030619China

Metabolic syndrome(Met S)is a chronic disease associated with the disturbance of gut microbiota *** derived from gut microbes play essential roles in Met S prevention and ***,we focused on the inhibitory effect of the extract of millet bran protein(EMBP)on a high-fat diet(HFD)-induced Met S,aiming to identify gut microbiota and their metabolites that involve in the anti-Met S activity of *** obesity,chronic inflammation,insulin resistance in Met S mouse models were abolished after EMBP *** protective mechanism of EMBP against HFD-induced Met S may depend on improved gut barrier *** microbiome analysis,we found that EMBP supplementation improved gut microbiome dysbiosis in Met S mice,specifically upregulating Bacteroides *** fecal microbiota transplantation(FMT)also demonstrated this *** addition,metabolomic analysis showed that EMBP mediates metabolic profiling reprogramming in Met S ***,a microbiota-derived metabolite,gamma-aminobutyric acid(GABA),is enriched by *** addition,exogenous GABA treatment produced a similar protective effect to EMBP by improving NRF2-dependent gut barrier function to protect HFDinduced Met *** results suggest that EMBP suppress host Met S by remodeling of gut microbiota as an effective candidate for next-generation medicine food dual purpose dietary supplement to intervene in MetS.

关键词： Metabolic syndrome Gut microbiota Extract of millet bran protein Gamma-aminobutyric acid Gut barrier function

Progressive Kaposiform Hemangioendothelioma and Sirolimus-Related Severe Thrombocytopenia

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Progressive Kaposiform Hemangioendothelioma and Sirolimus-Re...

现场聚合制备锂离子电池用凝胶聚合物电解质研究进展

第十四届全国口腔病理学术会议

作者： Hanru Ying Congzhen qiao lizhen Wang Xiaoxi Lin Department of Plastic and Reconstructive Surgery Shanghai Ninth People's HospitalShanghai Jiao Tong University School of Medicine Department of Oral Pathology Shanghai Ninth People's HospitalShanghai Jiao Tong University School of Medicine

Objective:Kaposiform haemangioendothelioma is a locally invasive tumour with no reports of multifocal progression. Sirolimus,a mammalian target of rapamycin inhibitor,has been widely used to treat Kaposiform haemangioendothelioma. Here,we reported the first case of multifocal progressive Kaposiform haemangioendothelioma,wherein sirolimus treatment caused severe thrombocytopenia.

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硅酸盐学报 2013年第2期41卷 134-139页

作者：范欢欢周栋范丽珍石桥北京科技大学新材料技术研究院北京100083 深圳新宙邦科技股份有限公司广东深圳518118

高比能量锂离子电池是未来储能器件的发展方向。凝胶聚合物锂离子电池因易于加工并克服了以往液态锂离子电池因漏液而造成的安全性问题,成为近年来的研究热点。综述了目前凝胶聚合物电解质制备工艺中最受关注的现场聚合技术,介绍了反应... 详细信息

高比能量锂离子电池是未来储能器件的发展方向。凝胶聚合物锂离子电池因易于加工并克服了以往液态锂离子电池因漏液而造成的安全性问题,成为近年来的研究热点。综述了目前凝胶聚合物电解质制备工艺中最受关注的现场聚合技术,介绍了反应原理、工艺路线、成品性能等,并展望了现场聚合工艺作为新兴锂离子电池生产技术的发展趋势。

关键词：锂离子电池凝胶聚合物电解质现场聚合工艺