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Journal of Computational Mathematics 2006年第3期24卷 265-280页

作者： Qiang Du liyong zhu Department of Mathematics Pennsylvania State University University Park PA 16802 USA ICMSEC Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100080 China ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100080 China

In this paper, we study numerical approximations of a recently proposed phase field model for the vesicle membrane deformation governed by the variation of the elastic bending energy. To overcome the challenges of high order nonlinear differential systems and the nonlinear constraints associated with the problem, we present the phase field bending elasticity model in a nested saddle point formulation. A mixed finite element method is then employed to compute the equilibrium configuration of a vesicle membrane with prescribed volume and surface area. Coupling the approximation results for a related linearized problem and the general theory of Brezzi-Rappaz-Raviart, optimal order error estimates for the finite element approximations of the phase field model are obtained. Numerical results are provided to substantiate the derived estimates.

关键词： Bio-membrane Elastic bending energy Phase field Finite element Nestedmixed saddle point formulation Optimal error estimates.

Efficient and Stable Exponential Runge-Kutta Methods for Parabolic Equations

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Advances in Applied Mathematics and Mechanics 2017年第1期9卷 157-172页

作者： liyong zhu School of Mathematics and Systems Science Beihang UniversityXueyuan Road No.37Haidian DistrictBeijing 100191China

In this paper we develop explicit fast exponential Runge-Kutta methods for the numerical solutions of a class of parabolic *** incorporating the linear splitting technique into the explicit exponential Runge-Kutta schemes,we are able to greatly improve the numerical *** proposed numerical methods could be fast implemented through use of decompositions of compact spatial difference operators on a regular mesh together with discrete fast Fourier transform *** exponential Runge-Kutta schemes are easy to be adopted in adaptive temporal approximations with variable time step sizes,as well as applied to stiff nonlinearity and boundary conditions of different *** stabilities of the proposed schemes and their comparison with other schemes are *** also numerically demonstrate accuracy,stability and robustness of the proposed method through some typical model problems.

关键词： Exponential Runge-Kutta method explicit scheme linear splitting discrete fast Fourier transforms Allen-Cahn equation

An Explicit-Implicit Predictor-Corrector Domain Decomposition Method for Time Dependent Multi-Dimensional Convection Diffusion Equations

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Numerical Mathematics(Theory,Methods and Applications) 2009年第3期2卷 301-325页

作者： liyong zhu Guangwei Yuan Qiang Du Laboratory of Computational Physics Institute of Applied Physics andComputational Mathematics Beijing China. Division of Mathematical Sciences School of Physical and MathematicalSciences Nanyang Technological University Singapore 637371. Department of Mathematics Pennsylvania State University University ParkPA 16802 USA.

The numerical solution of large scale multi-dimensional convection diffusion equations often requires efficient parallel *** this work,we consider the extension of a recently proposed non-overlapping domain decomposition method for two dimensional time dependent convection diffusion equations with variable coefficients. By combining predictor-corrector technique,modified upwind differences with explicitimplicit coupling,the method under consideration provides intrinsic parallelism while maintaining good stability and ***,for multi-dimensional problems, the method can be readily implemented on a multi-processor system and does not have the limitation on the choice of subdomains required by some other similar predictor-corrector or stabilized *** properties of the method are demonstrated in this work through both rigorous mathematical analysis and numerical experiments.

关键词： Convection diffusion equation parallel algorithm domain decomposition modifiedupwind differences predictor-corrector explicit-implicit scheme convergence analysis.

The role of visceral adipose tissue on improvement in insulin sensitivity following Roux-en-Y gastric bypass:a study in Chinese diabetic patients with mild and central obesity

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Gastroenterology Report 2018年第4期6卷 298-303,I0002页

作者： Lei Zhao liyong zhu Zhihong Su Weizheng Li Pengzhou Li Yong Liu Shengping Liu Shaihong zhu Department of General Surgery Third Xiangya HospitalCentral South UniversityNo 138 Tongzipo RoadChangshaHunan 410013China Department of Gastrointestinal Surgery First Affiliated HospitalUniversity of South ChinaNo 69 Chuanshan RoadHengyangHunan 421001China

Background:Most Chinese patients with type 2 diabetes mellitus(T2DM)have mild obesity and central *** obesity is combined with insulin *** aim of this study was to assess the effect of abdominal adipose tissue on insulin-sensitivity improvement after Roux-en-Y gastric bypass(RYGB)in Chinese diabetic patients with mild and central ***:Seventeen T2DM patients with a mean body mass index of 30.3 kg/m^(2) were scheduled for laparoscopic RYGB.A hyperinsulinemic-euglycemic clamp and dual-energy X-ray absorptiometry were performed prior to surgery and 3 months after *** primary end points were the correlations between insulin sensitivity and abdominal adipose tissue,including visceral adipose tissue(VAT)and subcutaneous adipose tissue(SAT),before and 3 months after ***:Indices of peripheral insulin sensitivity,including glucose-disposal rate(M value)and glucose infusion rate,were significantly increased after ***-fat mass,VAT and SAT were significantly reduced after *** pre-operative M value was significantly correlated with VAT mass(r=–0.57,P=0.02),but not correlated with SAT mass.M value changes after RYGB were highly correlated with changes in VAT mass(r=–0.59,P=0.01),percentage of VAT mass(r=–0.66,P<0.01),VAT area(r=–0.56,P=0.02)and percentage of VAT area(r=–0.57,P=0.02).Conclusions:A significant correlation was observed between increased peripheral insulin sensitivity and decreased VAT following RYGB in Chinese patients with mild and central *** and SAT were significantly decreased with improved insulin sensitivity after *** mass may be considered as an indication for gastric bypass during patient selection.

关键词： Insulin sensitivity visceral adipose tissue gastric bypass hyperinsulinemic-euglycemic clamp type 2 diabetes mellitus non-morbid obesity

The Design and Construction of Jiangxi Red Tourism Resource E-C/C-E Bilingual Parallel Corpus

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International Journal of Technology Management 2015年第12期 63-66页

作者： Zhijuan zhu liyong zhu Jiangxi Science & Technology Normal University Nanchang 330013 China

On the basis of description of the necessity in construction of the Jiangxi red tourism resource E-C/C-E bilingual parallel corpus, this paper discusses the design and construction of the corpus. In its design, it describes the general design and the framework of the corpus, then it describes its construction including data collection, the standard for the sorted data, data selection, data digitalization, data tagging and data aligning. With the construction, it will not only realize purposes and functions of the corpus, but also provide others with ways or means to use the corpus and to establish such kind of corpus.

关键词： corpus construction Jiangxi red tourism resource bilingual parallel corpus

Construction of Jiangxi Tourism Resource E-C/C-E Parallel Corpus

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International Journal of Technology Management 2016年第11期 65-67页

作者： liyong zhu Zhijuan zhu Jiangxi Science & Technology Normal University Nanchang 330013 China

This paper discusses the construction of Jiangxi Tourism Resource E-C Parallel Courpus on the basis of description of the necessity in its construction. It first describes its framework, then its construction. In construction, it includes data collection, the standard for the sorted data, data selection, data digitalization, data tagging and data aligning. With the introduction of its construction, it realizes its purposes and functions of the corpus, but also provides others with ways or means to use the corpus and to establish such kind of corpus.

关键词： Jiangxi tourism resource parallel corpus E-C construction and application

The telomere-to-telomere gap-free reference genome of wild blueberry (Vaccinium duclouxii) provides its high soluble sugar and anthocyanin accumulation

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Horticulture Research 2023年第11期10卷 141-154页

作者： Tuo Zeng Zhijiao He Jiefang He Wei Lv Shixiang Huang Jiawen Li liyong zhu Shuang Wan Wanfei Zhou Zhengsong Yang Yatao Zhang Chong Luo Jiawei He Caiyun Wang Liangsheng Wang School of Life Sciences Guizhou Normal UniversityGuiyang 550000China Institute of Alpine Economic Plant Yunnan Academy of Agricultural SciencesLijiang 674199YunnanChina School of Advanced Agricultural Sciences Peking University100871 BeijingChina National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops College of Horticulture&Forestry SciencesHuazhong Agricultural UniversityWuhan 430070China Wuhan Benagen Technology Co. LtdWuhan 430070China Key Laboratory of Plant Resources Institute of BotanyChinese Academy of SciencesBeijing 100093China China National Botanical Garden Beijing 100093China University of Chinese Academy of Sciences Beijing 100049China

Vaccinium duclouxii,endemic to southwestern China,is a berry-producing shrub or small tree belonging to the Ericaceae family,with high nutritive,medicinal,and ornamental value,abundant germplasm resources,and good edible *** addition,*** exhibits strong tolerance to adverse environmental conditions,making it a promising candidate for research and offering wide-ranging possibilities for ***,the lack of *** genome sequence has hampered its development and ***,a high-quality telomere-to-telomere genome sequence of *** was de novo assembled and *** of 12 chromosomes were assembled into gap-free single contigs,providing the highest integrity and quality assembly reported so far for *** *** genome is 573.67 Mb,which encodes 41953 protein-coding *** transcriptomics and metabolomics analyses,we have uncovered the molecular mechanisms involved in sugar and acid accumulation and anthocyanin biosynthesis in *** provides essentialmolecular information for further research on the quality of ***,the high-quality telomere-to-telomere assembly of the *** genome will provide insights into the genomic evolution of Vaccinium and support advancements in blueberry genetics and molecular breeding.

关键词： sugar offering berry

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神经和体液调节在减重手术中的作用机制

中华消化外科杂志 2022年第11期21卷 1422-1427页

作者：朱利勇余芊芊朱晒红中南大学湘雅三医院减重代谢外科长沙410013

减重手术是目前已知能够持久治疗肥胖症及其相关并发症的有效措施。减重手术类型包括限制摄入型、吸收不良型和混合型,通过改变胃肠道解剖结构,减重手术可达到限制食物摄入、减少食物吸收、增加饱腹感、延长胃排空的效果以降低患者体质... 详细信息

减重手术是目前已知能够持久治疗肥胖症及其相关并发症的有效措施。减重手术类型包括限制摄入型、吸收不良型和混合型,通过改变胃肠道解剖结构,减重手术可达到限制食物摄入、减少食物吸收、增加饱腹感、延长胃排空的效果以降低患者体质量和调节代谢机制。减重手术可通过脑‑迷走神经‑味觉感受器的神经调节,使患者感觉特异性饱腹感,从而减少摄食;通过脑‑肠‑微生物轴即大脑、迷走神经、脊神经、肠神经系统的神经元通路以及信号通路,在维持体内平衡中发挥核心作用;通过脂肪因子、胆汁酸、激素等信号因子在体液调节中抑制高血压、糖尿病、非酒精性脂肪肝、心脑血管疾病的发展。因此,减重手术后代谢相关疾病的改善是神经、体液、微生物等多因素相互影响作用的结果。笔者回顾既往研究结果,探讨神经、体液因子调节在减重手术对体质量下降以及改善代谢相关疾病的机制。

关键词：肥胖症减重手术生理机制神经调节体液调节

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减重手术后复胖原因与治疗对策

中华消化外科杂志 2021年第9期20卷 943-948页

作者：朱晒红汤海波朱利勇中南大学湘雅三医院减重代谢外科长沙410013

减重手术是治疗肥胖症及其相关代谢疾病的有效方式,但病人术后复胖是常见和不容忽视的问题。术后复胖的原因复杂,需多学科团队全面评估和长期稳定随访:术后复胖病人的治疗方案应根据其解剖学情况、生活习惯、心理状态和依从性等方面给... 详细信息

减重手术是治疗肥胖症及其相关代谢疾病的有效方式,但病人术后复胖是常见和不容忽视的问题。术后复胖的原因复杂,需多学科团队全面评估和长期稳定随访:术后复胖病人的治疗方案应根据其解剖学情况、生活习惯、心理状态和依从性等方面给予个性化指导。笔者分析目前针对术后复胖影响因素的回顾性和前瞻性研究,总结关于术后复胖行为、药物和手术治疗效果的临床证据,提出需建立减重手术后复胖的统一诊断标准。通过前瞻性研究明确减重手术后病人复胖的预测因子、建立手术和非手术干预方式的最佳组合、探寻药物治疗的最佳时间节点,对于有效维持减重手术效果、防治术后复胖具有重要意义。

关键词：肥胖症减重手术复胖多学科协作修正手术

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腹腔镜袖状胃切除术规范化操作要点

中华消化外科杂志 2024年第8期23卷 1044-1048页

作者：朱利勇高祥李鹏洲朱晒红中南大学湘雅三医院胃肠疝与减重代谢外科长沙410013

肥胖是全球性公共健康问题,减重代谢手术是治疗肥胖症及相关并发症最有效的措施.随着减重代谢外科的发展,目前全国不同级别的医院相继开展减重代谢手术,尤其以腹腔镜袖状胃切除术最普及.由于手术操作的不规范导致术后并发症以及复胖等... 详细信息

肥胖是全球性公共健康问题,减重代谢手术是治疗肥胖症及相关并发症最有效的措施.随着减重代谢外科的发展,目前全国不同级别的医院相继开展减重代谢手术,尤其以腹腔镜袖状胃切除术最普及.由于手术操作的不规范导致术后并发症以及复胖等问题日益增加.笔者结合自身经验和中心特点,总结腹腔镜袖状胃切除术手术操作细节,以进一步规范腹腔镜袖状胃切除术操作,降低术后并发症发生率.

关键词：肥胖症减重代谢手术手术技巧规范化腹腔镜袖状胃切除术