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Stability of water yield in watersheds

Science China Earth Sciences 2024年第2期67卷 483-496页

作者： Yu YAN Zhiyong LIU Xiaohong CHEN liyan huang Center for Water Resources and Environment School of Civil EngineeringSun Yat-Sen UniversityGuangzhou510275China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai519082China

The hydrological system of a watershed is intricately influenced by both underlying characteristics and climate *** the variability in water yield is essential for effective water resources management and water security in the context of changing *** this study,we adopted the Budyko framework and leveraged simulations from the CMIP6 model to investigate the compensation effects of climate and underlying characteristics on watershed water *** on Taylor expansion and Budyko framework,we estimated the sensitivity of watershed water yield to climate and underlying characteristics(the first-and second-order partial derivatives).By combining external watershed characteristics(e.g.,water yield ratios and underlying characteristics)with internal sensitivity coefficients,this study further used vine copula and principal component analysis to quantify the stability of watershed water *** findings show:(1)Water-yield changes related to underlying characteristics could be offset by climate-related water-yield changes across all climate zones,maintaining the water yield ratio steady(i.e.,the compensation effects).(2)However,global watersheds will turn more sensitive to underlying characteristics and less sensitive to climate variation in the *** climate-and underlying-related sensitivities increase in watersheds with arid climates.(3)The stability of watershed water yield will gradually diminish in the *** 1901–1950to 2051–2100,the global stability of 280 watersheds drops from 0.054 to 0.021(i.e.,stability index identified by the joint probability).Particularly,the largest change in stability of water yield reaches-0.347±0.18 in arid *** semi-arid,semihumid,and humid regions,the changes are-0.039±0.010,-0.028±0.005,and-0.005±0.002,*** findings provide a reference for the future sustainable water resources development under climate change,highlighting the vulnerability of the water resources in ari

关键词： Hydrological system stability Compensation effects on water yield Sensitivities Budyko-Fu decomposition framework Global watersheds

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Reliability Growth Test Planning and Verification of Commercial Vehicles

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Automotive Innovation 2019年第4期2卷 328-337页

作者： Liu Jicheng huang liyan Zhou Renmin Markus Volmer Beiqi Foton Motor Co. Ltd.Beijing 102206China

Reliability and durability are two important technical indicators in automobile research and development.A research-and-design and testing organization can increase inherent quality attributes by adopting a systematic approach based on statistical tools and clearly defined *** process affects the design phase,validation through testing,and quality assurance in *** the basis of reliability growth theory and the Duane model,this study established an estimation method for the definition of the target mileage and specific test cycles in reliability growth testing.A construction method for defin-ing test conditions was proposed that adopts the theory of the design of *** simulation was conducted under a variety of typical test conditions including differing operation times,loads,and logistics modes to predict customer use and detect *** cases were then analyzed in *** the same time,a reliability growth prediction model was established on the basis of the initial test data and used for test process tracking and risk control.

关键词： Reliability Duane model Reliability growth prediction model Failure rate

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Secalonic acid D induces cell apoptosis in both sensitive and ABCG2-overexpressing multidrug resistant cancer cells through upregulating c-Jun expression

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Acta Pharmaceutica Sinica B 2019年第3期9卷 516-525页

作者： Hong Zhang liyan huang liyang Tao Jianye Zhang Fang Wang Xu Zhang Liwu Fu Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Esophageal Cancer InstituteGuangzhou510060China School of Pharmaceutical Sciences Guangzhou Medical UniversityGuangzhou511436China

Secalonic acid D(SAD) could inhibit cell growth in not only sensitive cells but also multidrug resistant(MDR) cells. However, the molecular mechanisms need to be elucidated. Here, we identified that SAD possessed potent cytotoxicity in 3 pairs of MDR and their parental sensitive cells including S1-MI-80 and S1,H460/MX20 and H460, MCF-7/ADR and MCF-7 cells. Furthermore, SAD induced cell G2/M phase arrest via the downregulation of cyclin B1 and the increase of CDC2 phosphorylation. Importantly, JNK pathway upregulated the expression of c-Jun in protein level and increased c-Jun phosphorylation induced by SAD, which was linked to cell apoptosis via c-Jun/Src/STAT3 pathway. To investigate the mechanisms of upregulation of c-Jun protein by SAD, the mR NA expression level and degradation of c-Jun were examined. We found that SAD did not alter the mR NA level of c-Jun but inhibited its proteasome-dependent degradation. Taken together, these results implicate that SAD induces cancer cell death through c-Jun/Src/STAT3 signaling axis by inhibiting the proteasome-dependent degradation of c-Jun in both sensitive cells and ATP-binding cassette transporter sub-family G member 2(ABCG2)-mediated MDR cells.

关键词： Multidrug resistance Secalonic acid D Apoptosis c-Jun ABCG2

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Vitamin D Status of Elite Athletes in Singapore and Its Associations With Muscle Function and Bone Health

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Journal of Science in Sport and Exercise 2021年第4期3卷 385-393页

作者： liyan huang Danny Lum Mohammad Haiyum Kirsty A.Fairbairn Sport Science and Sport Medicine Singapore Sport InstituteSport SingaporeSingaporeSingapore Physical Education and Sports Science National Institute of EducationNanyang Technological UniversitySingaporeSingapore School of Sports Health and LeisureRepublic PolytechnicSingaporeSingapore Performance Nutrition High Performance Sport New ZealandAucklandNew Zealand

Purpose The primary aim of this study is to determine the prevalence of vitamin D deficiency and insufficiency among Asian athletes participating in indoor and outdoor sports in equatorial *** aims are to examine the relationship between vitamin D status and skeletal muscle strength and performance,and bone *** Serum 25(OH)D concentrations were determined in 95 indoor and outdoor athletes across various *** muscle strength and performance were assessed using the isometric mid-thigh pull(IMTP),drop jump test and 30 m sprint *** Mineral Density(BMD)was measured using Dual-energy X-ray Absorptiometry(DXA).Results Mean serum 25(OH)D concentrations were 28.6±8.9 ng/mL among indoor,and 39.2±13.2 ng/mL among outdoor sport athletes respectively(P<0.05).More indoor sport athletes(62%)had insufficient vitamin D compared to outdoor sport athletes(30%)(P<0.05).Outdoor sport athletes exhibited significantly greater peak force generation than indoor sport athletes(2079±470 N vs.1869±546 N,P=0.027).Other markers of muscle function were not significantly different between *** and outdoor sport athletes did not have significantly different BMDs although none of the athletes studied presented with poor *** who were deficient in vitamin D had significantly lower BMD compared to athletes with sufficient vitamin D(P=0.01).Conclusion Forty-seven percent of Singaporean athletes studied had suboptimal vitamin D *** monitoring of vitamin D levels among indoor sport athletes should be in place to ensure optimal health and performance.

关键词： Vitamin D Athletes Sports Asia Muscle function

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Geophysical survey and geodynamic study of crust and upper mantle in the Qinghai-Tibet Plateau

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Episodes 2005年第4期28卷 263-273页

作者： Rui Gao Zhanwu Lu Qiusheng Li Ye Guan Jisheng Zhang Rizheng He liyan huang Lithosphere Research Centre Institute of Geology CAGS Beijing 100037 China.

The Qinghai-Tibet Plateau, covering a vast territory and characterized by an extremely complicated structure, is considered as the ideal region to study continentcontinent collision, convergence and subduction of plates, and formation of the plateau. Since 1958, a great number of geophysical surveys have been conducted on the crust and upper mantle of the Plateau, totaling about 45,000 km in line-length. Compilation and integration of the data from these surveys has provided new summary diagrams, enabling the authors to present a review of some of the remarkable achievements over the past 50 years.

关键词：青藏高原地质测量地球动力学地壳结构地幔大地构造

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Selection and Validation of Reference Genes for Normalization of RT-qPCR Analysis in Developing or Abiotic-Stressed Tissues of Loquat (Eriobotrya japonica)

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Phyton-International Journal of Experimental Botany 2023年第4期92卷 1185-1201页

作者： Shoukai Lin Shichang Xu liyan huang Fuxiang Qiu Yihong Zheng Qionghao Liu Shiwei Ma Bisha Wu Jincheng Wu Fujian Provincial Key Laboratory of Ecology-Toxicological Effects&Control for Emerging Contaminants College of Environmental and Biological EngineeringPutian UniversityPutian351100China Key Laboratory of Ecological Environment and Information Atlas(Putian University) Fujian Provincial UniversityPutian351100China

Loquat(Eriobotrya japonica Lindl.)is a subtropical evergreen fruit tree that produces fruits with abundant nutrients and medicinal *** suitable reference genes for a set of loquat samples before qRT-PCR experiments is essential for the accurate quantification of gene *** this study,eight candidate reference genes were selected from our previously published RNA-seq data,and primers for each candidate reference gene were designed and *** Cq values of the candidate reference genes were calculated by RT-qPCR in 31 different loquat samples,including 12 subgroups of developing or abiotic-stressed *** combinations of stable reference genes were screened according to a comprehensive rank,which was synthesized from the results of four algorithms,including the geNorm,NormFinder,BestKeeper andΔCt *** screened reference genes were verified by normalizing EjLGA1 in each *** obtained suitable combinations of reference genes for accurate normalization were GAPDH,EF1αand ACT for floral development;GAPDH,UBCE and ACT for fruit setting;EF1α,GAPDH and eIF2B for fruit ripening;ACT,EF1αand UBCE for leaves under heat stress;eIF2B,UBCE and EF1αfor leaves under freezing stress;EF1α,TUA and UBCE for leaves under salt stress;ACT,EF1αand eIF2B for immature pulp under freezing stress;ACT,UBCE and eIF2B for immature seeds under freezing stress;EF1α,eIF2B and UBCE for both immature pulp and seeds under freezing stress;UBCE,TUB and TUA for red-fleshed fruits under cold-storage stress;eIF2B,RPS3 and TUB for white-fleshed fruits under coldstorage stress;and eIF2B,UBCE and RPS3 for both red-and white-fleshed fruits under cold-storage *** study obtained different combinations of stable reference genes for accurate normalization in twelve subgroups of developing or abiotic-stressed tissues in *** our knowledge,this is the first report to obtain stable reference genes for normalizing gene expression of abiotic-stressed t

关键词： Loquat Eriobotrya japonica reference genes qRT-PCR gene expression normalization developing tissues abiotic-stressed tissues

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The Washback Effect of a High-stakes Oral Test

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山东师范大学外国语学院学报（基础英语教育） 2006年第5期8卷 30-39页

作者：黄丽燕广州市教育局教学研究室 510030

In 2004,Guangzhou Education Bureau introduced an English oral test into its existing Guangzhou Senior Secondary School Entrance Examination(hereafter,SSSEE)with the intention of shifting from grammar-based English teaching at junior secondary school to a communication-based teaching *** paper presents preliminary research findings related to the washback effects of the oral test on *** data were collected via focus groups and *** nature of the washback effects of the SSSEE English oral test is discussed from six *** study shows that washback is a complex phenomenon and it can be conceptualised via a multidimensional model.

关键词： washback English teaching high-stakes oral test

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Healthy lifestyles in relation to cardiometabolic diseases among schoolteachers:A cross-sectional study

Health Care Science

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Health Care Science 2023年第4期2卷 223-232页

作者： liyan huang Mengjie He Jie Shen Yiying Gong Hui Chen Xiaolin Xu Geng Zong Yan Zheng Chao Jiang Baohong Wang Ronghua Zhang Changzheng Yuan School of Public Health The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Institute of Nutrition and Food Safety Zhejiang Provincial Center for Disease Control and PreventionHangzhouChina The Key Laboratory of Nutrition Metabolism and Food SafetyShanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghaiChina Human Phenome Institute School of Life SciencesFudan UniversityShanghaiChina Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology Life Sciences InstituteZhejiang UniversityHangzhouChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of Nutrition Harvard T.H.Chan School of Public HealthBostonUSA

Background:We aimed to explore the associations of adherence to an overall healthy lifestyle with cardiometabolic diseases(CMDs)among schoolteachers in ***:We conducted a cross-sectional analysis among 2983 teachers(aged 39.8±9.3 years,73.8%women)in Zhejiang Province,China.A healthy lifestyle score(0–7)was constructed based on seven low-risk factors:healthy diet,noncurrent smoking,noncurrent drinking,regular exercise,normal body mass index(BMI),adequate sleep duration,and limited sedentary *** included self-reported hyperlipidemia,hypertension,diabetes,coronary heart disease,and ***-adjusted logistic regression models were used to evaluate the associations between healthy lifestyle and ***:A total of 493(16.5%)participants had at least one CMD,with hyperlipidemia,hypertension,and diabetes being the three leading *** point increment in a healthy lifestyle score was associated with 20%lower odds of having CMD(p-trend<0.001).Compared with 0–3 low-risk factors,the odds ratios(ORs)and 95%confidence intervals(CIs)were 0.66(0.50–0.88)for 4 low-risk factors and 0.51(0.39–0.67)for 5–7 low-risk *** observed independent associations for normal BMI(OR=0.50,95%CI=0.40–0.63),noncurrent drinking(OR=0.53,95%CI=0.36–0.77),and limited sedentary behavior(OR=0.77,95%CI=0.62–0.96)in relation to *** diet(OR=0.75,95%CI=0.55–1.01)exhibited marginally significant association with ***:Our findings suggest that adherence to an overall healthy lifestyle is associated with lower odds of CMD among schoolteachers.

关键词： healthy lifestyle cardiometabolic diseases schoolteachers cross-sectional study

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发展中国家发展贸易与保护环境的冲突与解决

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世界经济与政治论坛 2005年第3期 17-21页

作者：黄李焰陈少平福州大学法学院

发展中国家发展贸易与保护环境两者存在着冲突。然而,面对这一冲突,发展中国家可供选择的解决方法并不是很多,主要有加大对人力资源的整合与投入、积极参与国际贸易规则的谈判和制定以及在国内大力推行ISO14000系列标准等。

关键词：发展中国家对外贸易环境保护污染产品环境成本国际贸易

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文化创意产业对视觉传达设计教学改革的影响

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装饰 2010年第6期 143-144页

作者：黄丽燕仲恺农业工程学院艺术设计学院

文化创意产业化为视觉传达设计的未来提供了广阔的空间,而视觉传达教育则是文化创意人才培养最重要的途径,它们之间是相辅相成的。为了适应新时代对人才的新要求,从专业课程的设置、教学手段的改革、实习基地的建设,乃至师资力量的调配... 详细信息

文化创意产业化为视觉传达设计的未来提供了广阔的空间,而视觉传达教育则是文化创意人才培养最重要的途径,它们之间是相辅相成的。为了适应新时代对人才的新要求,从专业课程的设置、教学手段的改革、实习基地的建设,乃至师资力量的调配都需打破传统视觉传达设计的教学模式,探索视觉艺术教学改革的方向,从而改善和提高目前的教学质量。

关键词：文化创意产业视觉传达设计教学改革

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