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能谱纯化Sn 150 kV结合ADMIRE在腰椎CT检查中的价值

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CT理论与应用研究（中英文） 2024年第1期33卷 49-55页

作者：蒋东秦立新武汉市肺科医院放射科武汉430033

目的:研究能谱纯化(SPS)Sn 150 kV结合高级模拟迭代重建(ADMIRE)在腰椎CT检查中的可行性。方法:行腰椎CT检查的患者88例,年龄在25~65岁,BMI在18.5~25 kg/m^(2)的患者,分成对照组(A组)和试验组(B组),每组44例;A组管电压120 kV,B组管电压S... 详细信息

目的:研究能谱纯化(SPS)Sn 150 kV结合高级模拟迭代重建(ADMIRE)在腰椎CT检查中的可行性。方法:行腰椎CT检查的患者88例,年龄在25~65岁,BMI在18.5~25 kg/m^(2)的患者,分成对照组(A组)和试验组(B组),每组44例;A组管电压120 kV,B组管电压Sn 150 kV,其他扫描参数均一致,完成检查并比较两组的图像质量和辐射剂量。结果:A组和B组图像客观评价噪声存在统计学差异,A组图像噪声高于B组;主观评价3位诊断者的ICC为0.769,表示评价一致性较好;B组的辐射剂量低于A组30.31%。结论:采用能谱纯化Sn 150 kV结合ADMIRE,不但能有效减低辐射剂量,还可保证优质的图像质量,值得在成人腰椎CT中推广使用。

关键词：高级模拟迭代重建能谱纯化腰椎

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无砟轨道桩板结构路基设计计算

中国铁道科学 2007年第5期28卷 5-10页

作者：秦立新武汉大学土木建筑工程学院

鉴于无砟轨道桩板结构路基没有相应的设计规范,在分析其结构特点和使用要求的基础上,借鉴相关行业标准和研究成果,将荷载分为永久荷载、可变荷载和偶然荷载,提出按承载能力极限状态和正常使用极限状态分别进行荷载效应组合,取各自的最... 详细信息

鉴于无砟轨道桩板结构路基没有相应的设计规范,在分析其结构特点和使用要求的基础上,借鉴相关行业标准和研究成果,将荷载分为永久荷载、可变荷载和偶然荷载,提出按承载能力极限状态和正常使用极限状态分别进行荷载效应组合,取各自的最不利组合以分项系数形式的表达式进行桩板结构路基设计计算。对荷载分项系数、组合值系数、准永久值系数以及结构抗力设计值和正常使用规定限值提出建议值。建议：承载板长度宜取20-50 m、厚度宜取0.5-0.8 m,并按一定原则设置;桩间距纵向宜取5-10 m,横向宜与线间距相对应;设置过渡段以满足过渡衔接处差异沉降和竖向转角要求。

关键词：桩板结构路基无砟轨道荷载极限状态

Measurement of astrophysical S-factor for ^(9)Be(d, α_(0))^(7)Li and ^(9)Be(d, α_(1))^(7)Li^(*) reactions at low energies

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Chinese Physics C 2021年第2期45卷 394-397页

作者： Zhenglin Huang Bingjun Chen lixin qin Qian Zhang Fang Zhang Tieshan Wang Kaihong Fang School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China

The thick-target yield of the ^(9)Be(d,α0)7Li and ^(9)Be(d,α1)7Li*reactions has been first directly measured over deuteron energies from 66 to 94 *** obtained S(Ei)ofα0 andα1 have similar trends calculated by the thin-target yield,consistent with Yan’s report within the ***,the parametric expression of S(E)was obtained to calculate the theoretical thick target yield,and it roughly agrees with the experimental thick target yield.

关键词： astrophysical S-factor low energy d-^(9)Be reaction

子宫肌瘤患者行高强度聚焦超声消融术对妊娠的影响

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武警医学 2024年第2期35卷 157-160页

作者：董欣庞晓卿任鹏杨晓丹杜娟秦丽欣张亚琴石家庄市第六医院聚焦超声治疗科 050500

目的探讨子宫肌瘤患者行高强度聚焦超声消融术(FUAS)对妊娠的影响,并对影响妊娠的相关因素进行分析。方法回顾性分析2017-10至2021-01在石家庄市第六医院经FUAS治疗且有生育需求的子宫肌瘤患者136例。根据术后是否妊娠分为妊娠组和未妊... 详细信息

目的探讨子宫肌瘤患者行高强度聚焦超声消融术(FUAS)对妊娠的影响,并对影响妊娠的相关因素进行分析。方法回顾性分析2017-10至2021-01在石家庄市第六医院经FUAS治疗且有生育需求的子宫肌瘤患者136例。根据术后是否妊娠分为妊娠组和未妊娠组,对比患者一般资料,并对影响术后妊娠的因素进行分析。结果136例患者经FUAS治疗后,72例患者81次妊娠,妊娠率59.56%(81/136);已分娩72次(52.94%,72/136例),剖宫产46例,顺产26例,均未发生产后出血、子宫破裂等并发症。妊娠组与未妊娠组孕产史、肌瘤是否多发、肌瘤消融率、肌瘤缩小率及术后症状缓解方面,差异无统计学意义(P>0.05),两组间年龄、肌瘤类型及巨大肌瘤,差异有统计学意义(P<0.05),年龄小、浆膜下肌瘤、肌瘤<8 cm更容易妊娠。结论FUAS治疗后患者妊娠率较高,且分娩安全;患者的年龄、肌瘤类型及巨大肌瘤是影响术后妊娠的重要因素。

关键词：子宫肌瘤高强度聚焦超声妊娠分娩影响因素

5%苯醚·咯菌腈悬浮种衣剂的制备及其在半夏种子处理中的应用

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现代农药 2024年第2期23卷 58-61,90页

作者：文永超张海艳宋邦燕廖国会陈湘燕秦立新陈明贵何永福朱峰贵阳市南明区农业农村事业发展服务中心贵阳550002 贵州省农业科学院植物保护研究所贵州省农药风险监测中心贵阳550006

为探明成膜剂对悬浮种衣剂成膜效果的影响,采用湿法研磨法,对成膜剂进行筛选,研究5%苯醚·咯菌腈悬浮种衣剂配方的稳定性和对半夏种子安全性。确定5%苯醚·咯菌腈悬浮种衣剂的配方为:咯菌腈3%、苯醚甲环唑2%、脂肪醇聚氧乙烯醚1%、十二... 详细信息

为探明成膜剂对悬浮种衣剂成膜效果的影响,采用湿法研磨法,对成膜剂进行筛选,研究5%苯醚·咯菌腈悬浮种衣剂配方的稳定性和对半夏种子安全性。确定5%苯醚·咯菌腈悬浮种衣剂的配方为:咯菌腈3%、苯醚甲环唑2%、脂肪醇聚氧乙烯醚1%、十二烷基苯磺酸钠1%、环氧大豆油1%、乙二醇1%、黄原胶0.5%、壳聚糖0.5%、碱性玫瑰精0.5%,水补足100%。所制悬浮种衣剂各项指标均符合产品质量标准的要求,成膜效果良好,对半夏种子发芽率无影响。

关键词：成膜剂悬浮种衣剂苯醚甲环唑咯菌腈半夏发芽率

共享门诊管理模式在类风湿关节炎患者中的应用研究

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护士进修杂志 2024年第18期39卷 1989-1994页

作者：张彩虹成亚慧褚文玲樊鑫国严春华曾莉张培莉陆慧秦立新上海市光华中西医结合医院上海200052 同济大学附属同济医院上海200052

目的评价共享门诊管理模式在类风湿关节炎(rheumatoid arthritis,RA)患者中的应用效果。方法便利选取2023年2-6月在上海市光华中西医结合医院关节内科门诊就诊的94例RA患者,按随机数字表法分为观察组和对照组各47例。观察组采用共享门... 详细信息

目的评价共享门诊管理模式在类风湿关节炎(rheumatoid arthritis,RA)患者中的应用效果。方法便利选取2023年2-6月在上海市光华中西医结合医院关节内科门诊就诊的94例RA患者,按随机数字表法分为观察组和对照组各47例。观察组采用共享门诊管理模式,对照组采用常规门诊护理,比较实施前后2组患者疾病知识掌握水平、自我效能及抑郁水平。结果实施3个月后,观察组疾病知识掌握得分和自我效能得分均高于对照组(P<0.001),抑郁水平低于对照组(P<0.001),差异均有统计学意义。结论应用共享门诊管理模式可有效提高RA患者的疾病知识水平、自我效能,减轻患者的抑郁情绪。

关键词：类风湿关节炎共享门诊自我效能管理模式护理

Cretaceous integrative stratigraphy,biotas,and paleogeographical evolution of the qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1229-1289页

作者： Dangpeng XI Guobiao LI Shijun JIANG Xin RAO Tian JIANG Tianyang WANG Zuohuan qin Yasu WANG Jianzhong JIA Muhammad KAMRAN Zhongye SHI Yuyang WU Panxi WANG lixin SUN qinggao ZENG Xiaoqiao WAN State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing 100083China College of Oceanography Hohai UniversityNanjing 213200China Key Laboratory of Palaeobiology and Petroleum Stratigraphy Nanjing Institute of Geology and PaleontologyChinese Academy of SciencesNanjing 210008China State Key Laboratory of Tibetan Plateau Earth System Environmentand Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China China National Offshore Oil Corporation Limited Beijing 100028China Shanghai Science and Technology Museum Shanghai 200120China Xizang Bureau of Geological and Mineral Exploration and Development Lhasa 850000China Tianjin Geological Survey Center of China Geological Survey Tianjin 300170China

The Cretaceous Period is a vital time interval in deciphering the evolutionary history of the Neo-Tethys Ocean and the convergence of different plates and blocks across the qinghai-Tibetan Plateau.A detailed stratigraphic framework and paleogeographic patterns are the basis for understanding the evolution of the Neo-Tethys Ocean and the formation of the qinghaiTibetan ***,the Cretaceous stratigraphy,biota,paleogeography,and major geological events in the qinghai-Tibetan Plateau are analyzed to establish an integrative stratigraphic framework,reconstruct the paleogeography during the Cretaceous Period,and decode the history of the major geological *** Cretaceous rocks of the qinghai-Tibetan Plateau and its surrounding area are predominantly marine deposits,with a small amount of interbedded marine-terrestrial and terrestrial *** Indus-Yarlung Tsangpo Suture Zone was responsible for the deposition of deep marine sediments dominated by ophiolite suites and radiolarian *** the south,the Tethys Himalayas and Indus Basin received marine sediments of varying depths and lithology;to the north,the Xigaze and Ladakh forearc basins are also filled with marine *** Lhasa Block,Karakorum Block,western Tarim Basin,and West Burma block consist of shallow marine,interbedded marine-terrestrial,and terrestrial *** Qiangtang Basin and other areas are dominated by terrestrial *** Cretaceous strata of the qinghai-Tibetan Plateau and its surrounding areas are widely distributed and diversified,with abundant foraminifera,calcareous nannofossils,radiolarians,ammonites,bivalves,and *** the basis of integrated lithostratigraphic,biostratigraphic,geochronologic,and chemostratigraphic analyses,we proposed herein a comprehensive stratigraphic framework for the Cretaceous Period of the eastern *** analyzing the Cretaceous biota of different biogeographic zones from eastern Neo-Tethys and its surrounding a

关键词： qinghai-Tibetan Plateau Tethys Cretaceous Stratigraphy Biota Paleogeography

Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3543-3560页

作者： lixin Zhao Yuguang Zhu Hua Tao Xiying Chen Feng Yin Yingyi Zhang Jianfeng qin Yongyin Huang Bikun Cai Yonghao Lin Jiaxiang Wu Yu Zhang Lu Liang Ao Shen Xi-Yong Yu The Fifth Affiliated Hospital Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target and Clinical PharmacologyNMPA&State Key LaboratorySchool of Pharmaceutical SciencesGuangzhou Medical UniversityGuangzhou 511436China

Pulmonary fibrosis poses a significant health threat with very limited therapeutic options *** this study,we reported the enhanced expression of mesenchymal homobox 1(MEOX1)in pulmonary fibrosis patients,especially in their fibroblasts and endothelial cells,and confirmed MEOX1 as a central orchestrator in the activation of profibrotic *** high-throughput screening,we identified Ailanthone(AIL)from a natural compound library as the first small molecule capable of directly targeting and suppressing *** demonstrated the ability to inhibit both the activation of fibroblasts and endothelial-to-mesenchymal transition of endothelial cells when challenged by transforming growth factor-b1(TGF-b1).In an animal model of bleomycin-induced pulmonary fibrosis,AIL effectively mitigated the fibrotic process and restored respiratory ***,AIL acted as a suppressor of MEOX1 by disrupting the interaction between the transcription factor JUN and the promoter of MEOX1,thereby inhibiting MEOX1 expression and *** summary,our findings pinpointed MEOX1 as a cell-specific and clinically translatable target in ***,we demonstrated the potent anti-fibrotic effect of AIL in pulmonary fibrosis,specifically through the suppression of JUN-dependent MEOX1 activation.

关键词： Ailanthone MEOX1 Pulmonary fibrosis JUN TGF-b1 High-throughput screening Natural product

Miura origami based reconfigurable polarization converter for multifunctional control of electromagnetic waves

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Photonics Research 2024年第3期12卷 581-586页

作者： ZHIBIAO ZHU YONGFENG LI ZHE qin lixin JIANG WENJIE WANG HONGYA CHEN JIAFU WANG YONGQIANG PANG SHAOBO QU Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051China School of Electronic Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

Polarization is one of the basic characteristics of electromagnetic(EM)waves,and its flexible control is very important in many practical *** present,most of the multifunction polarization metasurfaces are electrically tunable based on PIN and varactor diodes,which are easy to operate and have strong real-time ***,there are still some problems in them,such as few degrees of freedom of planar structure control,complex circuit,bulky sample,and high *** view of these shortcomings,this paper proposes a Miura origami based reconfigurable polarization conversion metasurface for multifunctional control of EM *** interaction between the electric dipoles is changed by adjusting the folding angleθ,thereby tuning the operating frequency of the polarization conversion and the polarization state of the reflected *** mechanical control method brings more degrees of freedom to manipulate EM *** the processed sample is with lightweight and low *** verify the performance of the proposed origami polarization converter,a Miura origami structure loaded with metal split rings is designed and *** operating frequency of the structure can be tuned in different folding *** addition,by controlling the folding angleθ,linear-to-linear and linear-to-circular polarization converters can be realized at different folding *** proposed Miura origami polarization conversion metasurface provides a new idea for reconfigurable linear polarization conversion and multifunctional devices.

关键词： polarization reconfigurable tuning