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Stability and vibration of a helical rod constrained by a cylinder

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Acta Mechanica Sinica 2007年第2期23卷 215-219页

作者： Yanzhu liu liwei Sheng Department of Engineering Mechanics Shanghai Jiao Tong University Shanghai 200030 China

The stability and vibration of an elastic rod with a circular cross section under the constraint of a cylinder is discussed. The differential equations of dynamics of the constrained rod are established with Euler＇s angles as variables describing the attitude of the cross section. The existence conditions of helical equilibrium under constraint are discussed as a special configuration of the rod. The stability of the helical equilibrium is discussed in the realms of statics and dynamics, respectively. Necessary conditions for the stability of helical rod are derived in space domain and time domain, and the difference and relationship between Lyapunov＇s and Euler＇s stability concepts are discussed. The free frequency of flexural vibration of the helical rod with cylinder constraint is obtained in analytical form.

关键词： Thin elastic rod . Cylinder constraint Stability.Flexural vibration

The Probability Analysis for the Many-Versus-One Guerrilla War

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Journal of Systems Science & Complexity 2015年第3期28卷 645-660页

作者： liu liwei LI Jianjun QIAN Linfang School of Science Nanjing University of Science and Technology School of Mechanical Engineering Nanjing University of Science and Technology

This paper discusses a stochastic duel model between two forces. On one side is the guerrilla(or terrorists) which has only one weapon(or person), and on the other an organized force of some sort which has many weapons. The model is called the many-versus-one guerrilla war. The guerrilla side has a number of advantages such as choice of location and time of engagement, concealment by topography, observation of the intended target, and line of fire. The authors present these advantages in what they believe are a realistic scenario of a duel between the guerrilla force and the organized force. By the four suppositions coinciding with the practical duel background, the paper presents the formulas to calculate the satisfying probability, the weak satisfying probability, and the acceptable probability of the attack side.

关键词： Fokker-Planck equation guerrilla war Markov chains military operational research stochastic duel.

Introduction to the Special Issue on Fluorescence Lifetime Imaging Microscopy(FLIM)

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Journal of Innovative Optical Health Sciences 2019年第5期12卷 1-2页

作者： Junle Qu liwei liu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060P.R.China

Fluorescence Lifetime Imaging Microscopy(FLIM)is an advanced tool that enables the description of exponential decay rate distribution of fuorescent molecules in the *** technique has been broadly used in biomedicine,material science,chemistry,and other related research fields,due to its ability to illustrate both localization of specific fuorophores and fuorophores'local microenvironment,and it is superior to fluorescence intensity based imaging.

关键词： Fluorescence exponential enable

Application of in situ cultivation in marine microbial resource mining

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Marine Life Science & Technology 2021年第2期3卷 148-161页

作者： Dawoon Jung liwei liu Shan He Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center College of Food and Pharmaceutical SciencesNingbo UniversityNingbo315832China

Microbial communities in marine habitats are regarded as underexplored reservoirs for discovering new natural products with potential ***,only a few microbes in nature can be cultivated in the *** has led to the development of a variety of isolation and cultivation methods,and in situ cultivation is one of the most *** in situ cultivation methods,with the same basic principle,have been applied to a variety of environmental *** with conventional approaches,these new methods are able to cultivate previously uncultured and phylogenetically novel microbes,many with biotechnological *** review introduces the various in situ cultivation methods for the isolation of previously uncultured microbial species and their potential for marine microbial resource ***,studies that investigated the key and previously unidentified mechanisms of growing uncultivated microorganisms by in situ cultivation,which will shed light on the understanding of microbial uncultivability,were also reviewed.

关键词： Uncultured microorganism Marine microbial resource In situ cultivation Microbial diversity

Cloning of the kininogen gene from Lampetra japonica provides insights into its phylogeny in vertebrates

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Journal of Genetics and Genomics 2009年第2期36卷 109-115页

作者： liwei Zhou Xin liu Ping Jin Qingwei Li College of Life Sciences Liaoning Normal University Dalian 116029 China

Kininogens, the precursors of bradykinins, ubiquitously exist in vertebrates, including mammals, birds, amphibians, and fishes. To elucidate the phylogeny of kininogen genes in early vertebrates, we cloned the full-length cDNA of kininogen gene from the liver of Lampetra japonica. The open reading frame of this sequence contained 546 bp and encoded 181 amino acids, including a cystatin domain without the canonical binding site for cysteine proteinases and a bradykinin domain. Our results suggested that in lampreys and most of other vertebrates, there might be only one kininogen gene, which was fused by certain sequences during vertebrate evolution and encoded proteins with more functions; however, another special kininogen gene, only encoding the bradykinin domain with multiple copies in some species, arose only in amphibians for adapting themselves to the unique environment. Using reverse transcription PCR, kininogen mRNA was also detected in lamprey gut, kidney, and leukocyte, but absent in lamprey buccal gland. Our findings may provide insights into the phylogeny of kininogen genes as well as other gene families in vertebrates.

关键词： kininogen Lampetrajaponica phylogeny bradykinin domain cystatin domain tissue distribution

Development of a hydrogen peroxide-responsive and oxygen-carrying nanoemulsion for photodynamic therapy against hypoxic tumors using phase inversion composition method

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Journal of Innovative Optical Health Sciences 2021年第2期4卷 75-83页

作者： Liang Hong Jia Zhang Junxian Geng Junle Qu liwei liu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic Engineering Shenzhen University Shenzhen 518060P.R.China

Photodynamic therapy(PDT)has become an attractive tumor treatment modality because of its noninvasive feature and low side ***,extreme hypoxia inside solid tumors severely impedes PDT therapeutic *** overcome this obstacle,various strategies have been developed *** them,in situ oxygen generation,which relies on the decom-position of tumor endogenous H_(2)O_(2),and oxygen delivery tactic using high oxygen loading capacity of hemoglobin or perfluorocarbons,have been widely *** in situ oxygen generation strategy has high specificity to tumors,but its oxygen-generating efficiency is lim-ited by the intrinsically low tumor H_(2)O_(2)*** contrast,the oxygen delivery approach holds advantage of high oxygen loading efficiency,nevertheless lacks tumor *** this work,we prepared a nanoemulsion system containing H_(2)O_(2)-responsive catalase,highly efficient ox-ygen carrier perfiuoropolyether(PFPE),and a near-infrared(NIR)light activatable photo-sensitizer IR780,to combine the high tumor specificity of the in situ oxygen generation strategy and the high efficiency of the oxygen delivery *** concisely prepared nanoplatform exhibited enhanced and H_(2)O_(2)-controllable production of singlet oxygen under light excitation,satisfactory cytocompatibility,and ability to kill cancer cells under NIR light *** highlights the potential of this novel nanoplatform for highly efficient and selective NIR light mediated PDT against hypoxic *** research provides new insight into the design of intelligent nanoplatform for relieving tumor hypoxia and enhancing the oxygen-dependent PDT effects in hypoxic tumors.

关键词： Hypoxia catalase oxygen delivery perfluorocarbon near-infrared

Deep learning autofluorescence-harmonic microscopy

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Light(Science & Applications) 2022年第4期11卷 697-710页

作者： Binglin Shen Shaowen liu Yanping Li Ying Pan Yuan Lu Rui Hu Junle Qu liwei liu Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province and Ministry of Education College of Physics and Optoelectronic EngineeringShenzhen University518060 ShenzhenChina Shenzhen Meitu.Innovation Technology LTD 518060 ShenzhenChina. China-Japan Union Hospital of Jilin University 130033 ChangchunChina The Sixth People's Hospital of Shenzhen 518052 ShenzhenChina

Laser scanning microscopy has inherent tradeoffs between imaging speed,field of view(FOV),and spatial resolution due to the limitations of sophisticated mechanical and optical setups,and deep learning networks have emerged to overcome these limitations without changing the ***,we demonstrate deep learning autofluorescence-harmonic microscopy(DLAM)based on self-alignment attention-guided residual-in-residual dense generative adversarial networks to close the gap between speed,FOV;and *** the framework,we demonstrate label-free large-field multimodal imaging of clinicopathological tissues with enhanced spatial resolution and running time *** quality assessments show that the attention-guided residual dense conneaions minimize the persistent noise,distortions,and scanning fringes that degrade the autofluorescence-harmonic images and avoid reconstruction artifaas in the output *** the advantages of high contrast,high fidelity,and high speed in image reconstruction,DLAM can act as a powerful tool for the noninvasive evaluation of diseases,neural activity,and embryogenesis.

关键词： networks Deep harmonic

Fast fluorescence lifetime imaging techniques:A review on challenge and development

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Journal of Innovative Optical Health Sciences 2019年第5期12卷 3-29页

作者： Xiongbo liu Danying Lin Wolfgang Becker Jingjing Niu Bin Yu liwei liu Junle Qu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen University Shenzhen 518060 P.R.China Becker&Hickl GmbH Nunsdorfer Ring 7-9 Berlin 12277Germany

Fluorescence lifetime imaging microscopy(FLIM)is increasingly used in biomedicine,material science,chemistry,and other related research fields,because of its advantages of high specificity and sensitivity in monitoring cellular microenvironments,studying interaction between proteins,metabolic state,screening drugs and analyzing their efficacy,characterizing novel materials,and diagnosing early ***,there is a large interest in obtaining FLIM data within an acquisition time as short as ***,there is currently a technology that advances towards faster and faster FLIM ***,the maximum speed of a recording technique is only part of the *** acquisition time of a FLIM image is a complex function of many *** include the photon rate that can be obtained from the sample,the amount of information a technique extracts from the decay functions,the fficiency at which it determines fluorescence decay parameters from the recorded photons,the demands for the accuracy of these parameters,the number of pixels,and the lateral and axial resolutions that are obtained in biological *** from a discussion of the parameters which determine the acquisition time,this review will describe existing and emerging FLIM techniques and data analysis algo-rithms,and analyze their performance and recording speed in biological and biomedical applications.

关键词： Fluorescence lifetime imaging microscopy(FLIM) acquisitin time imaging speed dead time photon fficiency time domain frequency domain scanning wide-field imaging time-correlated single photon counting(TCSPC) gated detection gated image intensifer modulated inage intensifier SPAD array detector

Effect of Rapid Thermal Process on Oxygen Precipitates in Heavily Sb-Doped Silicon Wafer

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Journal of Rare Earths 2006年第Z1期24卷 104-106页

作者： Sun Shilong Hao Qiuyan Zhao liwei Teng Xiaoyun liu Caichi Xu Yuesheng Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China Institute of Information Functional Materials Hebei University of Technology Tianjin 300130 China

Oxygen precipitates in heavily Sb-doped silicon after rapid thermal process (RTP) in Ar ambient were investigated by RTP at high temperature following annealing at 800 ℃ for 4 h and 1000 ℃ for 16 h. RTP temperature and cooling rates were changed from 1200 to 1260 ℃ and from 10 to 100 ℃·s-1, respectively. The experiment results show that high density of oxygen precipitates is observed in heavily Sb-doped wafer. It is found that the oxygen precipitates in heavily Sb-doped silicon are enhanced at high cooling rate.

关键词： oxygen precipitates vacancy RTP, DZ heavily Sb-doped silicon