检索结果-南通市图书馆

Species-level Microbiota of Biting Midges and Ticks from Poyang Lake

Biomedical and Environmental Sciences 2024年第3期37卷 266-277,I0001-I0003页

作者： GONG Jian WANG Fei Fei liu yang qing PU Ji DONG Ling Zhi ZHANG Si Hui HUANG Zhen Zhou HUANG Yu Yuan LI Ya Ben yang Cai Xin TAO Yuan Meihui ZHAO Li Jun JIN Dong liu Li Yun yang Jing LU Shan Department of Epidemiology School of Public HealthShanxi Medical UniversityTaiyuan 030001ShanxiChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Jiangxi Provincial Key Laboratory of Animal-Origin and Vector-Borne Diseases Nanchang Center for Disease Control and PreventionNanchang 330038JiangxiChina Research Units of Discovery of Unknown Bacteria and Function Chinese Academy of Medical SciencesBeijing 100730China

Objective The purpose of this study was to investigate the bacterial communities of biting midges and ticks collected from three sites in the Poyang Lake area,namely,Qunlu Practice Base,Peach Blossom Garden,and Huangtong Animal Husbandry,and whether vectors carry any bacterial pathogens that may cause diseases to humans,to provide scientific basis for prospective pathogen discovery and disease prevention and *** Using a metataxonomics approach in concert with full-length 16S rRNA gene sequencing and operational phylogenetic unit(OPU)analysis,we characterized the species-level microbial community structure of two important vector species,biting midges and ticks,including 33 arthropod samples comprising 3,885 individuals,collected around Poyang *** A total of 662 OPUs were classified in biting midges,including 195 known species and 373 potentially new species,and 618 OPUs were classified in ticks,including 217 known species and 326 potentially new ***,OPUs with potentially pathogenicity were detected in both arthropod vectors,with 66 known species of biting midges reported to carry potential pathogens,including Asaia lannensis and Rickettsia bellii,compared to 50 in ticks,such as Acinetobacter lwoffii and Staphylococcus *** found that Proteobacteria was the most dominant group in both midges and ***,the outcomes demonstrated that the microbiota of midges and ticks tend to be governed by a few highly abundant *** sp7 was predominant in biting midges,while Coxiella sp1 was enriched in ***,Coxiella spp.,which may be essential for the survival of Haemaphysalis longicornis Neumann,were detected in all tick *** identification of dominant species and pathogens of biting midges and ticks in this study serves to broaden our knowledge associated to microbes of arthropod *** Biting midges and ticks carry large numbers of known and potentially novel bacteria,and carry a wide

关键词： Biting midge Tick Microbiota Pantoea Coxiella

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of dietary with Zhibai dihuang pills and gonadotropinreleasing-hormone-analogue on girls with precocious and rapidly progressive puberty

引用

World Journal of Clinical Cases 2024年第24期12卷 5534-5541页

作者： Xue-Mei Wang Wei Li liu-qing yang Rui Luo Chen-Chen Zhang Department of Pediatrics Ma’anshan Maternal and Child Health HospitalMa’anshan 243011Anhui ProvinceChina

BACKGROUND At present,the clinical mechanisms underlying precocious puberty remain unclear,making effective intervention for children experiencing this condition and rapidly progressive puberty *** To explore the effects of Zhibai dihuang pills and gonadotropin-releasing hormone analogue(GnRHa)on growth and ovarian function in girls with precocious *** The clinical data of 84 adolescent girls with precocious puberty and rapidly progressive puberty from February 2017 to August 2023 were retrospectively *** were divided into a control group and an observation group,with 42 cases in each *** control group received diet intervention combined with GnRHa treatment,while the observation group received diet intervention combined with Zhibai dihuang pills+GnRHa *** such as clinical efficacy,growth indicators,ovarian function,and adverse reactions were compared between the two *** The observation group showed superior clinical efficacy compared to the control group(P0.05).Post-intervention,the observation group exhibited significantly lower rates in growth,height,and bone age,along with reduced levels of progesterone,testosterone,estradiol,prolactin,luteinizing hormone,and follicle-stimulating hormone compared to the control group(P0.05).CONCLUSION Combining Zhibai dihuang pills with GnRHa and dietary intervention effectively improves growth,enhances ovarian function,and minimizes adverse reactions in adolescent girls with precocious and rapidly progressive puberty.

关键词： Zhibai dihuang pills Gonadotropin-releasing hormone analogue Dietary intervention Precocious puberty Rapidly progressive puberty Ovarian function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

长持时爆炸冲击波作用下钢梁动力响应分析

引用

科学技术与工程 2024年第4期24卷 1654-1661页

作者：杜晓庆费智达柳扬清邱涛上海大学力学与工程科学学院上海200444

大规模爆炸时引起的长持时平面爆炸波会造成结构的整体破坏,与接触爆炸或近场爆炸的破坏模式有显著差异,但相关研究不多。为研究长持时冲击波作用下钢梁的动力响应,首先基于耦合欧拉-拉格朗日方法建立了大型数值激波管模型,然后采用该... 详细信息

大规模爆炸时引起的长持时平面爆炸波会造成结构的整体破坏,与接触爆炸或近场爆炸的破坏模式有显著差异,但相关研究不多。为研究长持时冲击波作用下钢梁的动力响应,首先基于耦合欧拉-拉格朗日方法建立了大型数值激波管模型,然后采用该数值激波管得到作用在钢梁上的反射超压时程,最后通过显式动力学方法研究了冲击波入射方向、持时、超压等参数对钢梁破坏模式的影响规律。结果表明:本文提出的数值激波管模型能较好地模拟长持时爆炸波的绕射现象,可得到可靠的反射超压和冲量时程;随着冲击波入射角度的增加,简支钢梁跨中位移增大;冲击波超压峰值相同时,随着持时的增加,简支梁跨中的最大位移有增大的趋势,最大位移的增长速率则会变缓;简支钢梁在长持时爆炸冲击波作用下容易发生受弯破坏,梁跨中翼缘板会出现局部屈曲现象。

关键词：数值激波管长持时冲击波显式动力学动力响应

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

长效生长激素制剂研究现状及进展

引用

中国新药杂志 2024年第3期33卷 247-254页

作者：刘清扬张娟后子靖康琛刘鑫张波唐彦中国医学科学院北京协和医院北京100730 烟台毓璜顶医院烟台264000 北京中医药大学东直门医院北京100700 河北医科大学第二医院河北050000

生长激素缺乏症是一种生长激素分泌障碍所导致的内分泌疾病,主要特征是生长激素水平不足,无法维持正常的生长和代谢。其病因可能为先天性或后天性的,儿童生长激素缺乏症主要特征为身材矮小、生长障碍;成人生长激素缺乏症临床表现往往呈... 详细信息

生长激素缺乏症是一种生长激素分泌障碍所导致的内分泌疾病,主要特征是生长激素水平不足,无法维持正常的生长和代谢。其病因可能为先天性或后天性的,儿童生长激素缺乏症主要特征为身材矮小、生长障碍;成人生长激素缺乏症临床表现往往呈非特异性。目前标准治疗方案是使用外源性生长激素替代治疗,以短效重组人生长激素的使用最为常见,但需要每日皮下注射,会导致依从性差和疗效下降。长效生长激素制剂可减少给药注射频率,提高依从性和疗效,多种长效生长激素制剂目前处于不同的开发阶段。本文就长效生长激素制剂的研究现状和最新进展进行综述,以期为长效生长激素的使用提供参考。

关键词：生长激素缺乏症生长激素长效生长激素激素替代治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

糖尿病舌诊客观化研究进展

引用

中国现代药物应用 2024年第5期18卷 175-177页

作者：白雪刘庆阳辽宁中医药大学研究生学院中医内科学 110847 辽宁中医药大学附属医院内分泌科 110032

随着中医药现代化发展进程逐步加快,舌诊与现代科学技术的结合日益紧密,逐渐向规范化、客观化方向发展。近5年诸多研究者将舌图像输入计算机进行定量化的检测与分析,并将舌诊客观化参数应用于临床研究,初步实现舌诊客观化。本文从舌诊... 详细信息

随着中医药现代化发展进程逐步加快,舌诊与现代科学技术的结合日益紧密,逐渐向规范化、客观化方向发展。近5年诸多研究者将舌图像输入计算机进行定量化的检测与分析,并将舌诊客观化参数应用于临床研究,初步实现舌诊客观化。本文从舌诊客观化模型识别、糖尿病舌象分布特征、舌象与糖尿病的中医辨证分型、舌象与临床化验指标的相关性以及舌诊客观化研究现状方面进行梳理和综述,为舌诊研究的进一步发展提供参考依据。

关键词：糖尿病舌象客观化研究

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-Superelasticity NiTi Shape Memory Alloy by Directed Energy Deposition-Arc and Solution Heat Treatment

引用

Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 132-144页

作者： Junyi Ma Lin Yu qing yang Jie liu Lei yang State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430070China School of Transportation and Logistics Engineering Wuhan University of TechnologyWuhan430074China

Directed energy deposition-arc(DED-Arc)technology has the advantages of simple equipment,low manufacturing cost and high deposition rate,while the use of DED-Arc has problems of microstructure inhomogeneity,position dependence of macroscopic mechanical properties and ***,it is necessary to carry out a subsequent heat treatment to improve its microstructure uniformity,mechanical properties and *** this investigation,the DED-Arc 15-layer NiTi alloy thin-walled parts with the solution treatment at different process parameters were studied to analyze the effects of solution heat treatment on microstructure,phase composition,phase transformation,microhardness,tensile and *** temperature range of solution treatment is 800-1050℃,and the treatment time range is 1-5.5 *** results show that after solution treatment at 800℃/1 h,the content of precipitated phase decreases,the grain is refined,the microhardness increases,and the mechanical properties in the 0°direction are *** strain recovery rate after 10 tensile cycles has increased from 37.13%(as-built)to 49.25%(solid solution treatment).This research provides an effective post treatment method for high-performance DED-Arc NiTi shape memory alloys.

关键词： Directed energy deposition-arc(DED-Arc) Cold metal transfer(CMT) NiTi shape memory alloys Microstructure Phase transformation Solution heat treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

《第一批罕见病目录》孤儿药的国内外剂型差异及临床应用分析

引用

临床药物治疗杂志 2024年第1期22卷 31-36页

作者：刘清扬王少红后子靖左玮刘鑫唐彦张波中国医学科学院北京协和医学院北京协和医院药学部北京100730 北京中医药大学东直门医院药学部北京100700

目的比较《第一批罕见病目录》疾病孤儿药在美国FDA和我国国家药品监督管理局(NMPA)上市品种的剂型差异,为罕见病药物治疗和新剂型的研发提供参考。方法纳入美国FDA和我国NMPA均上市,并在《第一批罕见病目录》疾病治疗国存在剂型差异... 详细信息

目的比较《第一批罕见病目录》疾病孤儿药在美国FDA和我国国家药品监督管理局(NMPA)上市品种的剂型差异,为罕见病药物治疗和新剂型的研发提供参考。方法纳入美国FDA和我国NMPA均上市,并在《第一批罕见病目录》疾病治疗国存在剂型差异的孤儿药。对比美国FDA和我国NMPA均有相同通用名药物上市品种的剂型差异。分析国内暂无相关剂型的孤儿药在美国FDA孤儿药资格和获批上市时间、适应证和用法,以及在EMA获批上市情况和我国临床试验开展情况。结果截至2022年9月,《第一批罕见病目录》疾病中,有308种(43.5%,308/708)美国FDA上市的孤儿药在我国有相同通用名药物获批,其中55种(17.8%)与美国FDA存在剂型差异,8种孤儿药的11种剂型为美国FDA批准用于治疗《第一批罕见病目录》疾病的药物,涉及6种罕见病。结论与国外相比,我国罕见病治疗药物仍存在“药物可获得,但相关剂型不能满足临床需求”的现象,需进一步关注相同通用名药物的不同剂型能否满足罕见病治疗需求。

关键词：罕见病孤儿药剂型可及性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stress-assisted corrosion mechanism of 3Ni steel by using gradient boosting decision tree machining learning method

引用

International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1311-1321页

作者： Xiaojia yang Jinghuan Jia qing Li Renzheng Zhu Jike yang Zhiyong liu Xuequn Cheng Xiaogang Li Institute of Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China AECC Key Laboratory of Advanced Corrosion and Protection of Aeronautical Materials AECC Beijing Institute of Aeronautical MaterialsBeijing 100095China Shunde Innovation School University of Science and Technology BeijingFoshan 528399China

Traditional 3Ni weathering steel cannot completely meet the requirements for offshore engineering development,resulting in the design of novel 3Ni steel with the addition of microalloy elements such as Mn or Nb for strength enhancement becoming a *** stress-assisted corrosion behavior of a novel designed high-strength 3Ni steel was investigated in the current study using the corrosion big data *** information on the corrosion process was recorded using the galvanic corrosion current monitoring *** gradi-ent boosting decision tree(GBDT)machine learning method was used to mine the corrosion mechanism,and the importance of the struc-ture factor was *** exposure tests were conducted to verify the calculated results using the GBDT *** indic-ated that the GBDT method can be effectively used to study the influence of structural factors on the corrosion process of 3Ni ***-ferent mechanisms for the addition of Mn and Cu to the stress-assisted corrosion of 3Ni steel suggested that Mn and Cu have no obvious effect on the corrosion rate of non-stressed 3Ni steel during the early stage of *** the corrosion reached a stable state,the in-crease in Mn element content increased the corrosion rate of 3Ni steel,while Cu reduced this *** the presence of stress,the increase in Mn element content and Cu addition can inhibit the corrosion *** corrosion law of outdoor-exposed 3Ni steel is consistent with the law based on corrosion big data technology,verifying the reliability of the big data evaluation method and data prediction model selection.

关键词： weathering steel stress-assisted corrosion gradient boosting decision tree machining learning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Significantly Enhanced Energy Storage Performances of PEI-based Composites Utilizing Surface Functionalized ZrO_(2) Nanoparticles for High-Temperature Application

引用

Chinese Journal of Polymer Science 2024年第3期42卷 322-332,I0006页

作者： qing-qing liu Qiu-Hao Lin Xiao-Dong Qi Nan Zhang Ting Huang Jing-Hui yang Yong Wang School of Chemistry Southwest Jiaotong UniversityChengdu 610031China Key Laboratory of Advanced Technologies of Materials Ministry of Education of ChinaSouthwest Jiaotong UniversityChengdu 610031China

Polymer dielectrics with a high energy density and an available energy storage capacity have been playing an important role in advanced electronics and power systems. Nevertheless, the use of polymer dielectrics in harsh environments is limited by their low energy density at high temperatures. Herein, zirconium dioxide(ZrO_(2)) nanoparticles were decorated with amino group utilizing 4,4-methylenebis(phenyl isocyanate)(AMEO) and successfully incorporated into polyetherimide(PEI) matrix. The dielectric properties, breakdown strength, and energy storage performances of PEI/ZrO_(2)-AMEO nanocomposites were investigated from 25 ℃ to 150 ℃. It is found that the combination of moderate bandgap ZrO_(2) with modest dielectric constant and polar groups at interface with deep trap can offer an available strategy to simultaneously increase the dielectric constant and breakdown strength of polymer dielectrics. As a result, the composites containing ZrO_(2)-AMEO exhibit excellent energy storage performance at elevated temperatures. Specially, the PEI-based composites with 3 vol% ZrO_(2)-AMEO display a maximum discharged energy density(U_(d)) of 3.1 J/cm^(3) at 150 ℃, presenting 90% higher than that of neat PEI. This study may help to better develop the polymer-based dielectric composite applied at elevated temperatures.

关键词： Polyetherimide High temperature dielectric ZrO_(2) Interface

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of filler characteristics on particle removal in fluid catalytic cracking slurry under an alternating electric field

引用

Petroleum Science 2024年第3期21卷 2102-2111页

作者： Qiang Li Hui-Zhen yang Can yang qing-Zhu Qiu Wei-Wei Xu Zhao-Zeng liu College of New Energy China University of Petroleum(East China)Qingdao266580ShandongChina

The characteristics of the packing material under an alternating electric field are an important factor in the removal of FCCS *** this study,the electric field distribution of a separation unit consisting of packed spheres under an alternating electric field is simulated,and the movement mechanism of catalyst particles is ***"effective contact point"model is derived to predict the adsorption of filler contact points on catalyst particles under the alternating electric field,and the model is validated by simulations and *** numerical calculation and experimental results indicate that the electrical properties of the filler spheres,the filler angleθ,and the frequency f of the alternating electric field affect the adsorption of catalyst *** the frequency of the electric field increases,the particle removal efficiency of the high-conductivity filler(silicon carbide)increases and then settles,and the separation efficiency of the low-conductivity filler(glass,zirconia)is not sensitive to the change in electric field frequency.

关键词： Fluid catalyticcracking slurry(FCCS) Particle AC electric field Fillers Removal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：